RU2680801C2 - Композиции и способы для лечения хронического воспаления и воспалительных заболеваний - Google Patents

Композиции и способы для лечения хронического воспаления и воспалительных заболеваний Download PDF

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RU2680801C2
RU2680801C2 RU2015137659A RU2015137659A RU2680801C2 RU 2680801 C2 RU2680801 C2 RU 2680801C2 RU 2015137659 A RU2015137659 A RU 2015137659A RU 2015137659 A RU2015137659 A RU 2015137659A RU 2680801 C2 RU2680801 C2 RU 2680801C2
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pharmaceutical composition
weight
peg
disease
therapeutic compound
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RU2015137659A
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RU2015137659A (ru
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Робин Марк Баннистер
Джон Брю
Уилсон КАПАРОС-УОНДЕРЛИ
Сьюзанн Джейн ДИЛЛИ
Матео Ольга ПЛЕГЕСУЭЛОС
Грегори Алан Столофф
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ИнФерст Хэлткэр Лимитед
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
RU2015137659A 2013-02-04 2014-01-14 Композиции и способы для лечения хронического воспаления и воспалительных заболеваний RU2680801C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361752309P 2013-02-04 2013-02-04
US61/752,309 2013-02-04
PCT/EP2014/050627 WO2014117999A1 (en) 2013-02-04 2014-01-14 Compositions and methods for treating chronic inflammation and inflammatory diseases

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RU2015137659A RU2015137659A (ru) 2017-03-10
RU2680801C2 true RU2680801C2 (ru) 2019-02-27

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EP (1) EP2950821A1 (enExample)
JP (1) JP6474352B2 (enExample)
KR (1) KR20150129664A (enExample)
CN (1) CN105120900A (enExample)
AU (1) AU2014211715B2 (enExample)
BR (1) BR112015015870B1 (enExample)
CA (1) CA2898017A1 (enExample)
HK (1) HK1218621A1 (enExample)
IL (1) IL239920A0 (enExample)
MX (1) MX366317B (enExample)
RU (1) RU2680801C2 (enExample)
SG (1) SG11201505243PA (enExample)
WO (1) WO2014117999A1 (enExample)
ZA (1) ZA201505006B (enExample)

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RU2749857C1 (ru) * 2019-12-23 2021-06-17 Псарева Нелли Александровна Способ борьбы со средним и наружным отитом
RU2774778C1 (ru) * 2021-07-16 2022-06-22 федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр имени В.А. Алмазова" Министерства здравоохранения Российской Федерации Способ лечения системной формы болезни Стилла взрослых с применением колхицина

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US9271950B2 (en) 2010-10-29 2016-03-01 Infirst Healthcare Limited Compositions for treating chronic inflammation and inflammatory diseases
US11224659B2 (en) 2010-10-29 2022-01-18 Infirst Healthcare Limited Solid solution compositions and use in severe pain
US8895537B2 (en) 2010-10-29 2014-11-25 Infirst Healthcare Ltd. Compositions and methods for treating cardiovascular diseases
US9744132B2 (en) 2010-10-29 2017-08-29 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
US11202831B2 (en) 2010-10-29 2021-12-21 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US9308213B2 (en) 2010-10-29 2016-04-12 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
US10695431B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US11730709B2 (en) 2010-10-29 2023-08-22 Infirst Healthcare Limited Compositions and methods for treating severe pain
US10695432B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in severe pain
US9504664B2 (en) 2010-10-29 2016-11-29 Infirst Healthcare Limited Compositions and methods for treating severe pain
WO2017004142A1 (en) 2015-06-29 2017-01-05 Children's Medical Center Corporation Treatment for myopathy
CN108283637A (zh) * 2018-04-04 2018-07-17 无锡市儿童医院 辛伐他汀的应用
WO2019195943A1 (en) * 2018-04-13 2019-10-17 Urban Juve Provisions Inc. Cannabis root extract, method of manufacture, method of use
WO2020247385A1 (en) * 2019-06-03 2020-12-10 Immunolux International Corp. Smallpox vaccine and stem cells for treatment of disease
AU2020379828A1 (en) * 2019-11-06 2022-04-28 Smartech Topical, Inc. Topical formulations of cyclooxygenase inhibitors and their use
RU2752764C1 (ru) * 2020-12-14 2021-08-03 Общество с ограниченной ответственностью "Тривиум-ХХI" (ООО "Тривиум-ХХI") Фармацевтическая композиция, обладающая противовоспалительным действием
KR20240021751A (ko) 2021-03-27 2024-02-19 티알엑스 바이오사이언시스 리미티드 치료제의 생체 이용률이 향상된 조성물
RU2760220C1 (ru) * 2021-06-02 2021-11-22 Федеральное государственное бюджетное научное учреждение «Научно-исследовательский институт ревматологии имени В.А. Насоновой» (ФГБНУ НИИР им. В.А. Насоновой) Способ определения клинически значимой усталости у больного ревматоидным артритом на фоне 5-летней терапии базисными противовоспалительными препаратами или базисными противовоспалительными препаратами в комплексе с генно-инженерными биологическими препаратами и/или психофармакотерапией и сопутствующего расстройства тревожно-депрессивного спектра
WO2025122472A1 (en) * 2023-12-04 2025-06-12 Primus Pharmaceuticals, Inc. Emollient compositions comprising linoleic acid and conjugated linoleic acid and methods of use

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Cited By (6)

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Publication number Priority date Publication date Assignee Title
RU2810508C2 (ru) * 2019-04-30 2023-12-27 Паэн Байотекнолоджи Инк. Фармацевтическая композиция для профилактики или лечения миозита, содержащая выделенные митохондрии в качестве активного ингредиента
RU2749857C1 (ru) * 2019-12-23 2021-06-17 Псарева Нелли Александровна Способ борьбы со средним и наружным отитом
RU2774778C1 (ru) * 2021-07-16 2022-06-22 федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр имени В.А. Алмазова" Министерства здравоохранения Российской Федерации Способ лечения системной формы болезни Стилла взрослых с применением колхицина
RU2792058C1 (ru) * 2022-07-18 2023-03-16 Нина Александровна Горлова Крем для лечения воспалительных заболеваний кожи
RU2817050C1 (ru) * 2023-06-20 2024-04-09 Федеральное Государственное Бюджетное Учреждение "Национальный Медицинский Исследовательский Центр Оториноларингологии Федерального Медико-Биологического Агентства" (Фгбу Нмицо Фмба России) Способ комплексного восстановительного лечения хронического ларингита у пациентов с болезнью Шегрена
RU2824403C1 (ru) * 2024-06-06 2024-08-07 федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный аграрный университет" Гастропротектор для лечения гастрита у собак и кошек

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CN105120900A (zh) 2015-12-02
BR112015015870A2 (pt) 2017-07-11
RU2015137659A (ru) 2017-03-10
IL239920A0 (en) 2015-08-31
AU2014211715A1 (en) 2015-07-23
EP2950821A1 (en) 2015-12-09
MX366317B (es) 2019-07-03
WO2014117999A1 (en) 2014-08-07
JP2016506941A (ja) 2016-03-07
ZA201505006B (en) 2016-03-30
SG11201505243PA (en) 2015-08-28
CA2898017A1 (en) 2014-08-07
BR112015015870A8 (pt) 2018-01-16
BR112015015870B1 (pt) 2022-09-27
JP6474352B2 (ja) 2019-02-27
KR20150129664A (ko) 2015-11-20
MX2015009058A (es) 2016-01-08
AU2014211715B2 (en) 2016-08-25
HK1218621A1 (zh) 2017-03-03

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