RU2674995C2 - Фармацевтические комбинации - Google Patents
Фармацевтические комбинации Download PDFInfo
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- RU2674995C2 RU2674995C2 RU2015124954A RU2015124954A RU2674995C2 RU 2674995 C2 RU2674995 C2 RU 2674995C2 RU 2015124954 A RU2015124954 A RU 2015124954A RU 2015124954 A RU2015124954 A RU 2015124954A RU 2674995 C2 RU2674995 C2 RU 2674995C2
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- compound
- melanoma
- inhibitor compound
- pharmaceutically acceptable
- combination
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| WO2003077914A1 (en) * | 2002-03-13 | 2003-09-25 | Array Biopharma, Inc | N3 alkylated benzimidazole derivatives as mek inhibitors |
| US20050009767A1 (en) * | 2003-07-10 | 2005-01-13 | Icn Pharmaceuticals Switzerland Ag | Use of ribofuranose derivatives against inflammatory bowel diseases |
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| US5489608A (en) | 1989-12-21 | 1996-02-06 | Goedecke Aktiengesellschaft | Indolocarbazole derivatives and the use thereof |
| US5475085A (en) | 1991-02-07 | 1995-12-12 | Molecumetics, Ltd. | Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same |
| PT657458E (pt) | 1993-12-07 | 2002-02-28 | Lilly Co Eli | Inibidores de proteina cinase c |
| US5545636A (en) | 1993-12-23 | 1996-08-13 | Eli Lilly And Company | Protein kinase C inhibitors |
| CA2179650C (en) | 1993-12-23 | 2007-10-30 | William Francis Heath, Jr. | Bisindolemaleimides and their use as protein kinase c inhibitors |
| SI0776895T1 (en) | 1995-11-20 | 1999-04-30 | Eli Lilly And Company | Protein kinase C inhibitor |
| JP3811775B2 (ja) | 2000-07-19 | 2006-08-23 | ワーナー−ランバート カンパニー リミティド ライアビリティー カンパニー | ４−ヨードフェニルアミノベンズヒドロキサム酸の酸素化エステル |
| US6645970B2 (en) | 2000-11-07 | 2003-11-11 | Novartis Ag | Indolylmaleimide derivatives |
| TW200918046A (en) | 2002-04-03 | 2009-05-01 | Novartis Ag | Indolylmaleimide derivatives |
| SI1761528T1 (sl) | 2004-06-11 | 2008-06-30 | Japan Tobacco Inc | 5-amino-2,4,7-triokso-3,4,7,8-tetrahidro-2H-pirido(2,3-D)pirimidinski derivati in sorodne spojine za zdravljenje raka |
| ES2405785T3 (es) | 2005-05-18 | 2013-06-03 | Array Biopharma Inc. | Inhibidores heterocíclicos de MEK y métodos de uso de los mismos |
| MX2008000463A (es) | 2005-07-11 | 2008-03-11 | Novartis Ag | Derivados de indolil-maleimida. |
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2013
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- 2013-11-26 EP EP13802815.4A patent/EP2925366B1/en active Active
- 2013-11-26 PL PL13802815T patent/PL2925366T3/pl unknown
- 2013-11-26 CA CA2892578A patent/CA2892578C/en active Active
- 2013-11-26 ES ES13802815.4T patent/ES2669248T3/es active Active
- 2013-11-26 US US14/647,939 patent/US9446043B2/en active Active
- 2013-11-26 CN CN201380061889.8A patent/CN104812415A/zh active Pending
- 2013-11-26 RU RU2015124954A patent/RU2674995C2/ru active
- 2013-11-26 NZ NZ70880213A patent/NZ708802A/en unknown
- 2013-11-26 DK DK13802815.4T patent/DK2925366T3/en active
- 2013-11-26 AU AU2013352379A patent/AU2013352379B2/en active Active
- 2013-11-26 TR TR2018/06682T patent/TR201806682T4/tr unknown
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- 2013-11-26 JP JP2015545170A patent/JP6437444B2/ja active Active
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002038561A1 (en) * | 2000-11-07 | 2002-05-16 | Novartis Ag | Indolylmaleimide derivatives as protein kinase c inhibitors |
| WO2003077914A1 (en) * | 2002-03-13 | 2003-09-25 | Array Biopharma, Inc | N3 alkylated benzimidazole derivatives as mek inhibitors |
| US20050009767A1 (en) * | 2003-07-10 | 2005-01-13 | Icn Pharmaceuticals Switzerland Ag | Use of ribofuranose derivatives against inflammatory bowel diseases |
Non-Patent Citations (3)
| Title |
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| CAMPILLO N.E. In silico ADME Approaches // Frontiers in Drug Design & Discovery 4, 2009, стр. 320. PHENEGER J. et al. Characterization of ARRY-438162, a potent MEK inhibitor in combination with Methotreaxate or Ibuprofen in vivo modls of arthritis // American College of Rheumatology, Annual Scientific Meeting, 2006. U0126 Bis[amino[(2-aminophenyl)thio]methylene] butanedinitrile // Life Technolodies, 09.09.2011. Приказ 82 Министерства Здравоохранения Российской Федерации, 29.02.2000, стр. 4. * |
| WU X. et al. The protein kinase C inhibitor Enzastaurin exhibits antitumor activity against uveal melanoma // PLoS * |
| WU X. et al. The protein kinase C inhibitor Enzastaurin exhibits antitumor activity against uveal melanoma // PLoS ONE 12.01.2012 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2892578C (en) | 2021-01-12 |
| ES2669248T3 (es) | 2018-05-24 |
| UA115250C2 (uk) | 2017-10-10 |
| AU2013352379A1 (en) | 2015-06-11 |
| TR201806682T4 (tr) | 2018-06-21 |
| BR112015012497B1 (pt) | 2022-05-17 |
| AU2013352379B2 (en) | 2018-09-06 |
| HK1215789A1 (en) | 2016-09-15 |
| BR112015012497A8 (pt) | 2019-10-01 |
| US20150306101A1 (en) | 2015-10-29 |
| BR112015012497A2 (pt) | 2017-07-11 |
| NZ708802A (en) | 2019-09-27 |
| US9446043B2 (en) | 2016-09-20 |
| EP2925366B1 (en) | 2018-02-21 |
| JP6437444B2 (ja) | 2018-12-12 |
| JP2016501222A (ja) | 2016-01-18 |
| DK2925366T3 (en) | 2018-06-06 |
| EP2925366A1 (en) | 2015-10-07 |
| WO2014085381A1 (en) | 2014-06-05 |
| HUE037618T2 (hu) | 2018-09-28 |
| CA2892578A1 (en) | 2014-06-05 |
| RU2015124954A (ru) | 2017-01-11 |
| CN104812415A (zh) | 2015-07-29 |
| PL2925366T3 (pl) | 2018-08-31 |
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