RU2664691C2 - Стабильная фармацевтическая композиция на основе слитого белка tnfr:fc - Google Patents
Стабильная фармацевтическая композиция на основе слитого белка tnfr:fc Download PDFInfo
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- RU2664691C2 RU2664691C2 RU2015119603A RU2015119603A RU2664691C2 RU 2664691 C2 RU2664691 C2 RU 2664691C2 RU 2015119603 A RU2015119603 A RU 2015119603A RU 2015119603 A RU2015119603 A RU 2015119603A RU 2664691 C2 RU2664691 C2 RU 2664691C2
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- pharmaceutical composition
- etanercept
- stable pharmaceutical
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Classifications
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C—CHEMISTRY; METALLURGY
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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- C—CHEMISTRY; METALLURGY
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Landscapes
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- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Inorganic Chemistry (AREA)
Applications Claiming Priority (5)
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| IN1235KO2012 | 2012-10-26 | ||
| IN1235/KOL/2012 | 2012-10-26 | ||
| IN1236/KOL/2012 | 2012-10-26 | ||
| IN1236KO2012 | 2012-10-26 | ||
| PCT/IB2013/059612 WO2014064637A1 (en) | 2012-10-26 | 2013-10-24 | Stable pharmaceutical composition of tnfr:fc fusion protein |
Publications (2)
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| RU2015119603A RU2015119603A (ru) | 2016-12-20 |
| RU2664691C2 true RU2664691C2 (ru) | 2018-08-21 |
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| RU2015119603A RU2664691C2 (ru) | 2012-10-26 | 2013-10-24 | Стабильная фармацевтическая композиция на основе слитого белка tnfr:fc |
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| EP (1) | EP2919801B1 (enExample) |
| JP (1) | JP6431844B2 (enExample) |
| KR (1) | KR102132050B1 (enExample) |
| CN (1) | CN104936607A (enExample) |
| AU (1) | AU2013336279B2 (enExample) |
| BR (1) | BR112015009462A2 (enExample) |
| CA (1) | CA2889271A1 (enExample) |
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| PL (1) | PL2919801T3 (enExample) |
| PT (1) | PT2919801T (enExample) |
| RU (1) | RU2664691C2 (enExample) |
| WO (1) | WO2014064637A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
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| ES2776657T3 (es) | 2005-06-14 | 2020-07-31 | Amgen Inc | Formulaciones de proteínas autotamponantes |
| HK1221163A1 (zh) * | 2013-05-02 | 2017-05-26 | Mabxience, S.A. | Tnfr:fc融合多肽的替代配方 |
| JP6480154B2 (ja) * | 2014-11-06 | 2019-03-06 | 持田製薬株式会社 | エタネルセプトの凍結乾燥製剤 |
| MX389818B (es) * | 2015-08-13 | 2025-03-20 | Landsteiner Scient S A De C V | Composicion de estabilidad mejorada de etanercept. |
| ES2962373T3 (es) * | 2016-04-13 | 2024-03-18 | Medimmune Llc | Uso de aminoácidos como compuestos estabilizadores en composiciones farmacéuticas que contienen altas concentraciones de agentes terapéuticos basados en proteínas |
| EP3528787B1 (en) | 2016-10-21 | 2026-01-07 | Amgen Inc. | Pharmaceutical formulations and methods of making the same |
| CA3071930A1 (en) * | 2017-08-08 | 2019-02-14 | Csl Behring Ag | Hemopexin formulations |
| CA3042126A1 (en) | 2018-05-03 | 2019-11-03 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Methods of treating kawasaki disease |
| WO2022264097A1 (en) | 2021-06-17 | 2022-12-22 | Lupin Limited | Pharmaceutical composition of anti-tumour necrosis factor (anti-tnf) agent for management of infectious diseases caused by coronaviruses |
| WO2025245826A1 (zh) * | 2024-05-31 | 2025-12-04 | 荣昌生物制药(烟台)股份有限公司 | 环糊精及其衍生物作为保护剂在制备TACI-Fc融合蛋白液体药物制剂中的用途 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009133529A2 (en) * | 2008-04-30 | 2009-11-05 | Wockhardt Research Centre | Processes for refolding of insulin |
| WO2011141926A2 (en) * | 2010-05-10 | 2011-11-17 | Intas Biopharmaceuticals Limited | Liquid formulation of polypeptides containing an fc domain of an immunoglobulin |
| RU2460518C2 (ru) * | 2007-04-20 | 2012-09-10 | Институто Сьентифико И Текнолохико Де Наварра, С.А. | Наночастицы, включающие циклодекстрин и биологически активную молекулу, и их применение |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5215743A (en) | 1988-04-13 | 1993-06-01 | Maninder Singh | Tumor necrosis factor formulations |
| US5997856A (en) * | 1988-10-05 | 1999-12-07 | Chiron Corporation | Method and compositions for solubilization and stabilization of polypeptides, especially proteins |
| DE4239877C1 (de) * | 1992-11-27 | 1994-03-17 | Boehringer Ingelheim Int | Stabilisierte Superoxid-Dismutase (SOD)-Zusammensetzung |
| DE59805732D1 (de) * | 1997-09-23 | 2002-10-31 | Rentschler Biotech Gmbh | Flüssige interferon-beta-formulierungen |
| PL215168B1 (pl) * | 2002-02-27 | 2013-10-31 | Immunex Corp | Formulacja polipeptydowa |
| US20040033228A1 (en) * | 2002-08-16 | 2004-02-19 | Hans-Juergen Krause | Formulation of human antibodies for treating TNF-alpha associated disorders |
| ES2304602T3 (es) | 2003-02-28 | 2008-10-16 | Ares Trading S.A. | Formulaciones liquidas de la proteina de union al factor de necrosis tumoral tbp-1. |
| RU2560701C2 (ru) * | 2009-05-04 | 2015-08-20 | Эббви Байотекнолоджи Лтд. | Стабильные композиции с высокими концентрациями белков антител человека против tnf-альфа |
| AU2011325974B2 (en) * | 2010-11-11 | 2016-10-27 | Abbvie Biotechnology Ltd. | Improved high concentration anti-TNFalpha antibody liquid formulations |
| EP2699265B1 (en) * | 2011-04-20 | 2019-10-16 | Sandoz AG | STABLE PHARMACEUTICAL LIQUID FORMULATIONS OF THE FUSION PROTEIN TNFR:Fc |
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- 2013-10-24 EP EP13795585.2A patent/EP2919801B1/en active Active
- 2013-10-24 PL PL13795585T patent/PL2919801T3/pl unknown
- 2013-10-24 PT PT137955852T patent/PT2919801T/pt unknown
- 2013-10-24 ES ES13795585T patent/ES2806946T3/es active Active
- 2013-10-24 CA CA2889271A patent/CA2889271A1/en not_active Abandoned
- 2013-10-24 JP JP2015538612A patent/JP6431844B2/ja not_active Expired - Fee Related
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- 2013-10-24 US US14/438,404 patent/US10058589B2/en active Active
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- 2013-10-24 AU AU2013336279A patent/AU2013336279B2/en active Active
- 2013-10-24 RU RU2015119603A patent/RU2664691C2/ru active
- 2013-10-24 KR KR1020157012856A patent/KR102132050B1/ko not_active Expired - Fee Related
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2018
- 2018-04-23 US US15/959,650 patent/US20180236030A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2460518C2 (ru) * | 2007-04-20 | 2012-09-10 | Институто Сьентифико И Текнолохико Де Наварра, С.А. | Наночастицы, включающие циклодекстрин и биологически активную молекулу, и их применение |
| WO2009133529A2 (en) * | 2008-04-30 | 2009-11-05 | Wockhardt Research Centre | Processes for refolding of insulin |
| WO2011141926A2 (en) * | 2010-05-10 | 2011-11-17 | Intas Biopharmaceuticals Limited | Liquid formulation of polypeptides containing an fc domain of an immunoglobulin |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2919801A1 (en) | 2015-09-23 |
| CA2889271A1 (en) | 2014-05-01 |
| JP6431844B2 (ja) | 2018-11-28 |
| KR20150074069A (ko) | 2015-07-01 |
| US10058589B2 (en) | 2018-08-28 |
| AU2013336279A1 (en) | 2015-05-14 |
| MX2015005231A (es) | 2015-10-29 |
| US20150283241A1 (en) | 2015-10-08 |
| RU2015119603A (ru) | 2016-12-20 |
| WO2014064637A1 (en) | 2014-05-01 |
| BR112015009462A2 (pt) | 2017-07-04 |
| MX366622B (es) | 2019-07-16 |
| PL2919801T3 (pl) | 2021-01-25 |
| KR102132050B1 (ko) | 2020-07-10 |
| AU2013336279B2 (en) | 2018-07-19 |
| ES2806946T3 (es) | 2021-02-19 |
| CN104936607A (zh) | 2015-09-23 |
| JP2015535237A (ja) | 2015-12-10 |
| PT2919801T (pt) | 2020-07-30 |
| US20180236030A1 (en) | 2018-08-23 |
| EP2919801B1 (en) | 2020-04-29 |
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