RU2652345C2 - Кетопрофеновая композиция для местного применения - Google Patents

Кетопрофеновая композиция для местного применения Download PDF

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Publication number
RU2652345C2
RU2652345C2 RU2015115723A RU2015115723A RU2652345C2 RU 2652345 C2 RU2652345 C2 RU 2652345C2 RU 2015115723 A RU2015115723 A RU 2015115723A RU 2015115723 A RU2015115723 A RU 2015115723A RU 2652345 C2 RU2652345 C2 RU 2652345C2
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RU
Russia
Prior art keywords
ketoprofen
composition
percent
carbopol
polyacrylic acid
Prior art date
Application number
RU2015115723A
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English (en)
Russian (ru)
Other versions
RU2015115723A (ru
Inventor
Сервет Буюктимкин
Надир Буюктимкин
Джеймс Л. Йиджер
Original Assignee
Ахелиос Терапьютикс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Ахелиос Терапьютикс, Инк. filed Critical Ахелиос Терапьютикс, Инк.
Publication of RU2015115723A publication Critical patent/RU2015115723A/ru
Application granted granted Critical
Publication of RU2652345C2 publication Critical patent/RU2652345C2/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
RU2015115723A 2012-09-27 2013-09-24 Кетопрофеновая композиция для местного применения RU2652345C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261706163P 2012-09-27 2012-09-27
US61/706,163 2012-09-27
US13/826,706 2013-03-14
US13/826,706 US8822537B2 (en) 2012-09-27 2013-03-14 Topical ketoprofen composition
PCT/US2013/061403 WO2014052313A1 (en) 2012-09-27 2013-09-24 Topical ketoprofen composition

Publications (2)

Publication Number Publication Date
RU2015115723A RU2015115723A (ru) 2016-11-20
RU2652345C2 true RU2652345C2 (ru) 2018-04-25

Family

ID=50339476

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2015115723A RU2652345C2 (ru) 2012-09-27 2013-09-24 Кетопрофеновая композиция для местного применения

Country Status (13)

Country Link
US (1) US8822537B2 (enExample)
EP (1) EP2900231B1 (enExample)
JP (1) JP6238991B2 (enExample)
KR (1) KR102184245B1 (enExample)
AU (1) AU2013323766B2 (enExample)
BR (1) BR112015006790B1 (enExample)
CA (1) CA2885619C (enExample)
ES (1) ES2902850T3 (enExample)
IL (1) IL237810B (enExample)
MX (1) MX373916B (enExample)
NZ (1) NZ706108A (enExample)
RU (1) RU2652345C2 (enExample)
WO (1) WO2014052313A1 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2767646C (en) 2009-07-10 2019-01-29 President And Fellows Of Harvard College Permanently charged sodium and calcium channel blockers as anti-inflammatory agents
JP2017536421A (ja) * 2014-12-01 2017-12-07 アケリオス セラピューティクス，インコーポレーテッド 片頭痛及び疼痛に関連する状態を処置するための方法及び組成物
CN108348774A (zh) 2015-08-03 2018-07-31 哈佛大学校长及研究员协会 带电离子通道阻断剂及其应用
WO2017106714A1 (en) * 2015-12-16 2017-06-22 Achelios Therapeutics, Inc. Methods and compositions for treating peripheral neuropathy
KR20190003535A (ko) * 2016-03-31 2019-01-09 스마테크 토피칼, 인코포레이티드 전달 시스템
CA3079530A1 (en) * 2017-11-30 2019-06-06 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Stable liquid composition of ketoprofen, salts and enantiomers thereof
US10786485B1 (en) 2019-03-11 2020-09-29 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
CA3129131A1 (en) 2019-03-11 2020-09-17 Bridget Mccarthy Cole Charged ion channel blockers and methods for use
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
CN113924094A (zh) 2019-03-11 2022-01-11 诺西恩医疗公司 酯取代的离子通道阻滞剂及其使用方法
JP7678757B2 (ja) 2019-03-11 2025-05-16 ノシオン セラピューティクス，インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
AU2020379828A1 (en) * 2019-11-06 2022-04-28 Smartech Topical, Inc. Topical formulations of cyclooxygenase inhibitors and their use
EP4054586A4 (en) 2019-11-06 2023-11-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10842798B1 (en) 2019-11-06 2020-11-24 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US12162851B2 (en) 2020-03-11 2024-12-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
JP7708777B2 (ja) 2020-03-11 2025-07-15 ノシオン セラピューティクス，インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6423697B1 (en) * 1999-01-14 2002-07-23 Mark Friedman Intraoral topical anti-inflammatory treatment for relief of migraine, tension-type headache, post-traumatic headache, facial pain, and cervical-muscle spasm
US7235230B2 (en) * 2001-10-24 2007-06-26 Clariant Finance (Bvi) Limited Leave-on compositions for personal care
WO2007118605A1 (en) * 2006-04-18 2007-10-25 Dsm Ip Assets B.V. Cosmetic compositions comprising salicylic acid and ascorbic acid
RU2340335C2 (ru) * 2003-03-18 2008-12-10 Менарини Ричерке С.П.А. Стабилизированные композиции для местного применения, содержащие кетопрофен
US20110028555A1 (en) * 2004-06-15 2011-02-03 Hisamitsu Pharmaceutical Co., Inc. Antiinflammatory and Analgesic Preparation for External Use

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60155111A (ja) * 1983-10-20 1985-08-15 Hisamitsu Pharmaceut Co Inc 安定なケトプロフェン含有外用経皮製剤
US5863527A (en) * 1996-09-04 1999-01-26 The Proctor & Gamble Company Personal care compositions
FR2804024B1 (fr) * 2000-01-21 2002-09-13 Menarini France Nouvelles compositions pharmaceutiques a action anti- inflammatoire et leur procede de preparation
JP2004532254A (ja) * 2001-05-30 2004-10-21 ザ プロクター アンド ギャンブル カンパニー 結合剤としてアルファ−ベータ−不飽和エステルを含む局所化粧品用組成物
DE10141258B4 (de) * 2001-08-23 2004-09-23 Beiersdorf Ag Kosmetische und dermatologische Zubereitung und ihre Verwendung
EP1488787A1 (en) * 2003-06-20 2004-12-22 Berlin-Chemie Ag Topical stabilized formulations containing ketoprofen
ATE534373T1 (de) * 2003-10-10 2011-12-15 Antares Pharma Ipl Ag Transdermale pharmazeutische formulierung zur minimierung von rückständen auf der haut
PL1872796T3 (pl) * 2005-02-25 2012-01-31 Hisamitsu Pharmaceutical Co Preparat przezskórny do stosowania zewnętrznego zawierający niesteroidowy lek przeciwzapalny/przeciwbólowy
US8080237B2 (en) * 2005-09-15 2011-12-20 Benjamin Sredni Use of tellurium compounds for protection from ultra-violet radiation
WO2009139817A2 (en) * 2008-04-15 2009-11-19 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
US8409600B2 (en) * 2009-01-23 2013-04-02 J&E Solutions, Llc Methods for prevention and/or treatment of capsular contracture
WO2011075688A1 (en) * 2009-12-18 2011-06-23 Exodos Life Sciences Limited Partnership Methods and compositions for treating and preventing trigeminal autonomic cephalgias, migraine, and vascular conditions

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6423697B1 (en) * 1999-01-14 2002-07-23 Mark Friedman Intraoral topical anti-inflammatory treatment for relief of migraine, tension-type headache, post-traumatic headache, facial pain, and cervical-muscle spasm
US7235230B2 (en) * 2001-10-24 2007-06-26 Clariant Finance (Bvi) Limited Leave-on compositions for personal care
RU2340335C2 (ru) * 2003-03-18 2008-12-10 Менарини Ричерке С.П.А. Стабилизированные композиции для местного применения, содержащие кетопрофен
US20110028555A1 (en) * 2004-06-15 2011-02-03 Hisamitsu Pharmaceutical Co., Inc. Antiinflammatory and Analgesic Preparation for External Use
WO2007118605A1 (en) * 2006-04-18 2007-10-25 Dsm Ip Assets B.V. Cosmetic compositions comprising salicylic acid and ascorbic acid

Also Published As

Publication number Publication date
CA2885619A1 (en) 2014-04-03
ES2902850T3 (es) 2022-03-30
KR102184245B1 (ko) 2020-11-30
HK1212898A1 (en) 2016-06-24
MX373916B (es) 2020-07-10
CA2885619C (en) 2020-09-08
BR112015006790A2 (pt) 2017-07-04
JP6238991B2 (ja) 2017-11-29
MX2015004006A (es) 2015-10-29
US20140088195A1 (en) 2014-03-27
IL237810B (en) 2018-06-28
EP2900231B1 (en) 2021-11-03
BR112015006790B1 (pt) 2022-05-31
EP2900231A1 (en) 2015-08-05
US8822537B2 (en) 2014-09-02
AU2013323766B2 (en) 2017-08-17
JP2015531374A (ja) 2015-11-02
RU2015115723A (ru) 2016-11-20
AU2013323766A1 (en) 2015-04-09
KR20150074009A (ko) 2015-07-01
EP2900231A4 (en) 2016-03-02
NZ706108A (en) 2018-03-23
WO2014052313A1 (en) 2014-04-03

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20200925

NF4A Reinstatement of patent

Effective date: 20211013