IL237810B - Topical oil-in-water emulsion composition and use of a therapeutically effective amount of the composition for treating pain and migraine - Google Patents
Topical oil-in-water emulsion composition and use of a therapeutically effective amount of the composition for treating pain and migraineInfo
- Publication number
- IL237810B IL237810B IL237810A IL23781015A IL237810B IL 237810 B IL237810 B IL 237810B IL 237810 A IL237810 A IL 237810A IL 23781015 A IL23781015 A IL 23781015A IL 237810 B IL237810 B IL 237810B
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- migraine
- pain
- treatment
- effective amount
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261706163P | 2012-09-27 | 2012-09-27 | |
| US13/826,706 US8822537B2 (en) | 2012-09-27 | 2013-03-14 | Topical ketoprofen composition |
| PCT/US2013/061403 WO2014052313A1 (en) | 2012-09-27 | 2013-09-24 | Topical ketoprofen composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL237810B true IL237810B (en) | 2018-06-28 |
Family
ID=50339476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL237810A IL237810B (en) | 2012-09-27 | 2015-03-18 | Topical oil-in-water emulsion composition and use of a therapeutically effective amount of the composition for treating pain and migraine |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8822537B2 (enExample) |
| EP (1) | EP2900231B1 (enExample) |
| JP (1) | JP6238991B2 (enExample) |
| KR (1) | KR102184245B1 (enExample) |
| AU (1) | AU2013323766B2 (enExample) |
| BR (1) | BR112015006790B1 (enExample) |
| CA (1) | CA2885619C (enExample) |
| ES (1) | ES2902850T3 (enExample) |
| IL (1) | IL237810B (enExample) |
| MX (1) | MX373916B (enExample) |
| NZ (1) | NZ706108A (enExample) |
| RU (1) | RU2652345C2 (enExample) |
| WO (1) | WO2014052313A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2767646C (en) | 2009-07-10 | 2019-01-29 | President And Fellows Of Harvard College | Permanently charged sodium and calcium channel blockers as anti-inflammatory agents |
| JP2017536421A (ja) * | 2014-12-01 | 2017-12-07 | アケリオス セラピューティクス,インコーポレーテッド | 片頭痛及び疼痛に関連する状態を処置するための方法及び組成物 |
| CN108348774A (zh) | 2015-08-03 | 2018-07-31 | 哈佛大学校长及研究员协会 | 带电离子通道阻断剂及其应用 |
| WO2017106714A1 (en) * | 2015-12-16 | 2017-06-22 | Achelios Therapeutics, Inc. | Methods and compositions for treating peripheral neuropathy |
| KR20190003535A (ko) * | 2016-03-31 | 2019-01-09 | 스마테크 토피칼, 인코포레이티드 | 전달 시스템 |
| CA3079530A1 (en) * | 2017-11-30 | 2019-06-06 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. | Stable liquid composition of ketoprofen, salts and enantiomers thereof |
| US10786485B1 (en) | 2019-03-11 | 2020-09-29 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| CA3129131A1 (en) | 2019-03-11 | 2020-09-17 | Bridget Mccarthy Cole | Charged ion channel blockers and methods for use |
| US10780083B1 (en) | 2019-03-11 | 2020-09-22 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| CN113924094A (zh) | 2019-03-11 | 2022-01-11 | 诺西恩医疗公司 | 酯取代的离子通道阻滞剂及其使用方法 |
| JP7678757B2 (ja) | 2019-03-11 | 2025-05-16 | ノシオン セラピューティクス,インコーポレイテッド | 荷電したイオンチャンネル遮断薬および使用方法 |
| AU2020379828A1 (en) * | 2019-11-06 | 2022-04-28 | Smartech Topical, Inc. | Topical formulations of cyclooxygenase inhibitors and their use |
| EP4054586A4 (en) | 2019-11-06 | 2023-11-22 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| US10842798B1 (en) | 2019-11-06 | 2020-11-24 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| US12162851B2 (en) | 2020-03-11 | 2024-12-10 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| JP7708777B2 (ja) | 2020-03-11 | 2025-07-15 | ノシオン セラピューティクス,インコーポレイテッド | 荷電したイオンチャンネル遮断薬および使用方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60155111A (ja) * | 1983-10-20 | 1985-08-15 | Hisamitsu Pharmaceut Co Inc | 安定なケトプロフェン含有外用経皮製剤 |
| US5863527A (en) * | 1996-09-04 | 1999-01-26 | The Proctor & Gamble Company | Personal care compositions |
| US6423697B1 (en) * | 1999-01-14 | 2002-07-23 | Mark Friedman | Intraoral topical anti-inflammatory treatment for relief of migraine, tension-type headache, post-traumatic headache, facial pain, and cervical-muscle spasm |
| FR2804024B1 (fr) * | 2000-01-21 | 2002-09-13 | Menarini France | Nouvelles compositions pharmaceutiques a action anti- inflammatoire et leur procede de preparation |
| JP2004532254A (ja) * | 2001-05-30 | 2004-10-21 | ザ プロクター アンド ギャンブル カンパニー | 結合剤としてアルファ−ベータ−不飽和エステルを含む局所化粧品用組成物 |
| DE10141258B4 (de) * | 2001-08-23 | 2004-09-23 | Beiersdorf Ag | Kosmetische und dermatologische Zubereitung und ihre Verwendung |
| US7235230B2 (en) * | 2001-10-24 | 2007-06-26 | Clariant Finance (Bvi) Limited | Leave-on compositions for personal care |
| ITFI20030070A1 (it) * | 2003-03-18 | 2004-09-19 | Berlin Chemie Ag | Formulazioni topiche stabilizzate contenenti ketoprofene |
| EP1488787A1 (en) * | 2003-06-20 | 2004-12-22 | Berlin-Chemie Ag | Topical stabilized formulations containing ketoprofen |
| ATE534373T1 (de) * | 2003-10-10 | 2011-12-15 | Antares Pharma Ipl Ag | Transdermale pharmazeutische formulierung zur minimierung von rückständen auf der haut |
| US7928144B2 (en) * | 2004-06-15 | 2011-04-19 | Hisamitsu Pharmaceutical Co., Inc. | Antiinflammatory and analgesic preparation for external use |
| PL1872796T3 (pl) * | 2005-02-25 | 2012-01-31 | Hisamitsu Pharmaceutical Co | Preparat przezskórny do stosowania zewnętrznego zawierający niesteroidowy lek przeciwzapalny/przeciwbólowy |
| US8080237B2 (en) * | 2005-09-15 | 2011-12-20 | Benjamin Sredni | Use of tellurium compounds for protection from ultra-violet radiation |
| EP2010132A1 (en) * | 2006-04-18 | 2009-01-07 | DSMIP Assets B.V. | Cosmetic compositions comprising salicylic acid and ascorbic acid |
| WO2009139817A2 (en) * | 2008-04-15 | 2009-11-19 | Sarcode Corporation | Crystalline pharmaceutical and methods of preparation and use thereof |
| US8409600B2 (en) * | 2009-01-23 | 2013-04-02 | J&E Solutions, Llc | Methods for prevention and/or treatment of capsular contracture |
| WO2011075688A1 (en) * | 2009-12-18 | 2011-06-23 | Exodos Life Sciences Limited Partnership | Methods and compositions for treating and preventing trigeminal autonomic cephalgias, migraine, and vascular conditions |
-
2013
- 2013-03-14 US US13/826,706 patent/US8822537B2/en active Active
- 2013-09-24 NZ NZ706108A patent/NZ706108A/en not_active IP Right Cessation
- 2013-09-24 MX MX2015004006A patent/MX373916B/es active IP Right Grant
- 2013-09-24 JP JP2015534599A patent/JP6238991B2/ja active Active
- 2013-09-24 CA CA2885619A patent/CA2885619C/en active Active
- 2013-09-24 KR KR1020157010840A patent/KR102184245B1/ko active Active
- 2013-09-24 ES ES13842525T patent/ES2902850T3/es active Active
- 2013-09-24 RU RU2015115723A patent/RU2652345C2/ru active IP Right Revival
- 2013-09-24 AU AU2013323766A patent/AU2013323766B2/en not_active Ceased
- 2013-09-24 EP EP13842525.1A patent/EP2900231B1/en active Active
- 2013-09-24 WO PCT/US2013/061403 patent/WO2014052313A1/en not_active Ceased
- 2013-09-24 BR BR112015006790-5A patent/BR112015006790B1/pt not_active IP Right Cessation
-
2015
- 2015-03-18 IL IL237810A patent/IL237810B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CA2885619A1 (en) | 2014-04-03 |
| ES2902850T3 (es) | 2022-03-30 |
| KR102184245B1 (ko) | 2020-11-30 |
| HK1212898A1 (en) | 2016-06-24 |
| MX373916B (es) | 2020-07-10 |
| CA2885619C (en) | 2020-09-08 |
| BR112015006790A2 (pt) | 2017-07-04 |
| JP6238991B2 (ja) | 2017-11-29 |
| MX2015004006A (es) | 2015-10-29 |
| US20140088195A1 (en) | 2014-03-27 |
| EP2900231B1 (en) | 2021-11-03 |
| BR112015006790B1 (pt) | 2022-05-31 |
| EP2900231A1 (en) | 2015-08-05 |
| US8822537B2 (en) | 2014-09-02 |
| AU2013323766B2 (en) | 2017-08-17 |
| JP2015531374A (ja) | 2015-11-02 |
| RU2015115723A (ru) | 2016-11-20 |
| AU2013323766A1 (en) | 2015-04-09 |
| RU2652345C2 (ru) | 2018-04-25 |
| KR20150074009A (ko) | 2015-07-01 |
| EP2900231A4 (en) | 2016-03-02 |
| NZ706108A (en) | 2018-03-23 |
| WO2014052313A1 (en) | 2014-04-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |