IL237810B - Topical oil-in-water emulsion composition and use of a therapeutically effective amount of the composition for treating pain and migraine - Google Patents

Topical oil-in-water emulsion composition and use of a therapeutically effective amount of the composition for treating pain and migraine

Info

Publication number
IL237810B
IL237810B IL237810A IL23781015A IL237810B IL 237810 B IL237810 B IL 237810B IL 237810 A IL237810 A IL 237810A IL 23781015 A IL23781015 A IL 23781015A IL 237810 B IL237810 B IL 237810B
Authority
IL
Israel
Prior art keywords
preparation
migraine
pain
treatment
effective amount
Prior art date
Application number
IL237810A
Other languages
English (en)
Hebrew (he)
Original Assignee
Achelios Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Achelios Therapeutics Inc filed Critical Achelios Therapeutics Inc
Publication of IL237810B publication Critical patent/IL237810B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
IL237810A 2012-09-27 2015-03-18 Topical oil-in-water emulsion composition and use of a therapeutically effective amount of the composition for treating pain and migraine IL237810B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261706163P 2012-09-27 2012-09-27
US13/826,706 US8822537B2 (en) 2012-09-27 2013-03-14 Topical ketoprofen composition
PCT/US2013/061403 WO2014052313A1 (en) 2012-09-27 2013-09-24 Topical ketoprofen composition

Publications (1)

Publication Number Publication Date
IL237810B true IL237810B (en) 2018-06-28

Family

ID=50339476

Family Applications (1)

Application Number Title Priority Date Filing Date
IL237810A IL237810B (en) 2012-09-27 2015-03-18 Topical oil-in-water emulsion composition and use of a therapeutically effective amount of the composition for treating pain and migraine

Country Status (13)

Country Link
US (1) US8822537B2 (enExample)
EP (1) EP2900231B1 (enExample)
JP (1) JP6238991B2 (enExample)
KR (1) KR102184245B1 (enExample)
AU (1) AU2013323766B2 (enExample)
BR (1) BR112015006790B1 (enExample)
CA (1) CA2885619C (enExample)
ES (1) ES2902850T3 (enExample)
IL (1) IL237810B (enExample)
MX (1) MX373916B (enExample)
NZ (1) NZ706108A (enExample)
RU (1) RU2652345C2 (enExample)
WO (1) WO2014052313A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2995303A1 (en) 2009-07-10 2016-03-16 President and Fellows of Harvard College Permanently charged sodium and calcium channel blockers as anti-inflammatory agents
EP3226972A4 (en) * 2014-12-01 2018-08-08 Achelios Therapeutics, Inc. Methods and compositions for treating migraine and conditions associated with pain
WO2017024037A1 (en) 2015-08-03 2017-02-09 President And Fellows Of Harvard College Charged ion channel blockers and methods for use
US20180369174A1 (en) * 2015-12-16 2018-12-27 Achelios Therapeutics, Inc. Methods and compositions for treating peripheral neuropathy
JP2019510824A (ja) * 2016-03-31 2019-04-18 スマーテック・トピカル・インコーポレイテッドSMARTECH TOPICAL,Inc. 送達システム
EA202091229A1 (ru) * 2017-11-30 2020-08-19 Ацьенде Кимике Рьюните Анджелини Франческо А.К.Р.А.Ф. С.П.А. Стабильная жидкая композиция кетопрофена, его солей и энантиомеров
EP3937945A4 (en) 2019-03-11 2023-01-04 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10786485B1 (en) 2019-03-11 2020-09-29 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
MA55307A (fr) 2019-03-11 2022-01-19 Nocion Therapeutics Inc Bloqueurs de canaux ioniques chargés et procédés d'utilisation
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
BR112021017809A2 (pt) 2019-03-11 2021-11-23 Nocion Therapeutics Inc Bloqueadores de canais iônicos substituídos por éster e métodos para uso
CA3139559A1 (en) 2019-05-09 2020-11-12 Apkarian Technologies Llc Methods and compositions for treating pain
WO2021091585A1 (en) 2019-11-06 2021-05-14 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10933055B1 (en) 2019-11-06 2021-03-02 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US20220378729A1 (en) * 2019-11-06 2022-12-01 Smartech Topical, Inc. Topical formulations of cyclooxygenase inhibitors and their use
US12162851B2 (en) 2020-03-11 2024-12-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
JP7708777B2 (ja) 2020-03-11 2025-07-15 ノシオン セラピューティクス,インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60155111A (ja) * 1983-10-20 1985-08-15 Hisamitsu Pharmaceut Co Inc 安定なケトプロフェン含有外用経皮製剤
US5863527A (en) * 1996-09-04 1999-01-26 The Proctor & Gamble Company Personal care compositions
US6423697B1 (en) * 1999-01-14 2002-07-23 Mark Friedman Intraoral topical anti-inflammatory treatment for relief of migraine, tension-type headache, post-traumatic headache, facial pain, and cervical-muscle spasm
FR2804024B1 (fr) 2000-01-21 2002-09-13 Menarini France Nouvelles compositions pharmaceutiques a action anti- inflammatoire et leur procede de preparation
WO2005039531A1 (en) * 2003-10-10 2005-05-06 Antares Pharma Ipl Ag Transdermal pharmaceutical formulation for minimizing skin residues
CA2448065A1 (en) * 2001-05-30 2002-12-05 The Procter & Gamble Company Topical cosmetic composition comprising an alpha-beta-unsaturated ester as bonding agent
DE10141258B4 (de) * 2001-08-23 2004-09-23 Beiersdorf Ag Kosmetische und dermatologische Zubereitung und ihre Verwendung
US7235230B2 (en) * 2001-10-24 2007-06-26 Clariant Finance (Bvi) Limited Leave-on compositions for personal care
ITFI20030070A1 (it) * 2003-03-18 2004-09-19 Berlin Chemie Ag Formulazioni topiche stabilizzate contenenti ketoprofene
EP1488787A1 (en) * 2003-06-20 2004-12-22 Berlin-Chemie Ag Topical stabilized formulations containing ketoprofen
ES2590258T3 (es) * 2004-06-15 2016-11-21 Hisamitsu Pharmaceutical Co., Inc. Preparación antiinflamatoria y analgésica para uso externo
WO2006090833A1 (ja) * 2005-02-25 2006-08-31 Hisamitsu Pharmaceutical Co., Inc. 非ステロイド系消炎鎮痛剤を含有する外用経皮製剤
US8080237B2 (en) * 2005-09-15 2011-12-20 Benjamin Sredni Use of tellurium compounds for protection from ultra-violet radiation
US20090263340A1 (en) * 2006-04-18 2009-10-22 Dsm Ip Assets B.V. Cosmetic compositions
WO2009139817A2 (en) * 2008-04-15 2009-11-19 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
US8409600B2 (en) * 2009-01-23 2013-04-02 J&E Solutions, Llc Methods for prevention and/or treatment of capsular contracture
WO2011075688A1 (en) * 2009-12-18 2011-06-23 Exodos Life Sciences Limited Partnership Methods and compositions for treating and preventing trigeminal autonomic cephalgias, migraine, and vascular conditions

Also Published As

Publication number Publication date
BR112015006790A2 (pt) 2017-07-04
EP2900231B1 (en) 2021-11-03
AU2013323766B2 (en) 2017-08-17
EP2900231A1 (en) 2015-08-05
RU2015115723A (ru) 2016-11-20
RU2652345C2 (ru) 2018-04-25
JP2015531374A (ja) 2015-11-02
NZ706108A (en) 2018-03-23
CA2885619A1 (en) 2014-04-03
JP6238991B2 (ja) 2017-11-29
MX373916B (es) 2020-07-10
ES2902850T3 (es) 2022-03-30
AU2013323766A1 (en) 2015-04-09
US20140088195A1 (en) 2014-03-27
US8822537B2 (en) 2014-09-02
MX2015004006A (es) 2015-10-29
EP2900231A4 (en) 2016-03-02
KR20150074009A (ko) 2015-07-01
KR102184245B1 (ko) 2020-11-30
BR112015006790B1 (pt) 2022-05-31
CA2885619C (en) 2020-09-08
WO2014052313A1 (en) 2014-04-03
HK1212898A1 (en) 2016-06-24

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