RU2648144C2 - КОМПОЗИЦИИ, СОДЕРЖАЩИЕ ГЕТЕРОГЕННЫЕ ПОПУЛЯЦИИ РЕКОМБИНАНТНЫХ БЕЛКОВ ЧЕЛОВЕЧЕСКОГО ФАКТОРА СВЕРТЫВАНИЯ КРОВИ Ха - Google Patents
КОМПОЗИЦИИ, СОДЕРЖАЩИЕ ГЕТЕРОГЕННЫЕ ПОПУЛЯЦИИ РЕКОМБИНАНТНЫХ БЕЛКОВ ЧЕЛОВЕЧЕСКОГО ФАКТОРА СВЕРТЫВАНИЯ КРОВИ Ха Download PDFInfo
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201361881834P | 2013-09-24 | 2013-09-24 | |
| US61/881,834 | 2013-09-24 | ||
| PCT/IB2014/064564 WO2015044836A1 (en) | 2013-09-24 | 2014-09-16 | Compositions comprising heterogeneous populations of recombinant human clotting factor xa proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2016108608A RU2016108608A (ru) | 2017-10-26 |
| RU2648144C2 true RU2648144C2 (ru) | 2018-03-22 |
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| Application Number | Title | Priority Date | Filing Date |
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| RU2016108608A RU2648144C2 (ru) | 2013-09-24 | 2014-09-16 | КОМПОЗИЦИИ, СОДЕРЖАЩИЕ ГЕТЕРОГЕННЫЕ ПОПУЛЯЦИИ РЕКОМБИНАНТНЫХ БЕЛКОВ ЧЕЛОВЕЧЕСКОГО ФАКТОРА СВЕРТЫВАНИЯ КРОВИ Ха |
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| HK1215196A1 (zh) | 2013-01-31 | 2016-08-19 | 辉瑞公司 | 用於抵消因子xa抑制的组合物和方法 |
| AU2014326257B2 (en) | 2013-09-24 | 2017-08-10 | Pfizer Inc. | Compositions comprising heterogeneous populations of recombinant human clotting factor Xa proteins |
| PE20190661A1 (es) * | 2016-06-17 | 2019-05-08 | Portola Pharm Inc | Preparacion de derivados del factor xa |
| EP3722418A1 (en) * | 2019-04-08 | 2020-10-14 | AB Enzymes Oy | Solution stable enzyme composition |
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| US20090175931A1 (en) * | 2005-11-15 | 2009-07-09 | Camire Rodney M | Compositions and methods for modulating hemostasis |
| RU2396347C2 (ru) * | 2004-08-17 | 2010-08-10 | Ксл Бехринг Гмбх | Модифицированные витамин к-зависимые полипептиды |
| WO2013049804A1 (en) * | 2011-09-30 | 2013-04-04 | The Children's Hospital Of Philadelphia | Compositions and methods for modulating hemostasis |
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| US5597799A (en) | 1990-09-04 | 1997-01-28 | Cor Therapeutics, Inc. | Recombinant agents affecting thrombosis |
| AT405517B (de) | 1997-02-27 | 1999-09-27 | Immuno Ag | Faktor x-deletionsmutanten und analoge davon |
| AT405516B (de) | 1997-02-27 | 1999-09-27 | Immuno Ag | Faktor x-analoge mit modifizierter proteasespaltstelle |
| AT410216B (de) | 1999-08-10 | 2003-03-25 | Baxter Ag | Faktor x-analogon mit verbesserter aktivierbarkeit |
| AU2001249389A1 (en) | 2000-03-22 | 2001-10-03 | The Children's Hospital Of Philadelphia | Modified blood clotting factors and methods of use |
| FR2831170B1 (fr) | 2001-10-19 | 2004-03-19 | Inst Nat Sante Rech Med | Proteines c modifiees activables directement par la thrombine |
| FR2841904B1 (fr) | 2002-07-03 | 2004-08-20 | Inst Nat Sante Rech Med | Analogues de facteurs x clivables par la thrombine |
| EP1728798A1 (en) | 2005-06-01 | 2006-12-06 | ZLB Behring GmbH | Coagulation factor X polypeptides with modified activation properties |
| EP1820508A1 (en) | 2006-02-21 | 2007-08-22 | CSL Behring GmbH | Coagulation factor X polypeptides with modified activation properties |
| DK2915564T3 (da) * | 2007-09-28 | 2021-02-08 | Alexion Pharma Inc | Antidoter mod faktor XA-inhibitorer og fremgangsmåder til anvendelse deraf |
| AU2009264282B2 (en) | 2008-06-24 | 2013-04-18 | Octapharma Ag | A process of purifying coagulation factor VIII |
| JP5709316B2 (ja) | 2008-11-14 | 2015-04-30 | ポートラ ファーマシューティカルズ， インコーポレイテッド | 第Ｘａ因子阻害剤のための解毒剤および血液凝固剤と組み合わせて該解毒剤を使用する方法 |
| US8436144B2 (en) | 2008-12-19 | 2013-05-07 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Serine protease derivatives and uses in the prevention or the treatment of blood coagulation disorders |
| EP2453910B1 (en) * | 2009-07-15 | 2016-08-31 | Portola Pharmaceuticals, Inc. | Unit dose formulation of antidote for factor xa inhibitors for use in preventing bleeding |
| EA201291482A1 (ru) * | 2010-07-09 | 2013-10-30 | Байоджен Айдек Хемофилия Инк. | Химерные факторы коагуляции |
| FR2972114B1 (fr) | 2011-03-01 | 2013-03-15 | Univ Grenoble 1 | Un nouveau leurre moleculaire procoagulant pour le traitement des hemophiles a ou b avec ou sans inhibiteur |
| MX365612B (es) | 2012-07-25 | 2019-06-07 | Catalyst Biosciences Inc | Polipeptidos de factor x modificados y usos de los mismos. |
| HK1215196A1 (zh) | 2013-01-31 | 2016-08-19 | 辉瑞公司 | 用於抵消因子xa抑制的组合物和方法 |
| AU2014326257B2 (en) | 2013-09-24 | 2017-08-10 | Pfizer Inc. | Compositions comprising heterogeneous populations of recombinant human clotting factor Xa proteins |
| CA2928762A1 (en) | 2013-11-01 | 2015-05-07 | The Children's Hospital Of Philadelphia | Compositions and methods for increasing the half-life of factor xa |
| MX375355B (es) | 2014-01-24 | 2025-03-04 | Pfizer | Una variante del factor xa para usarse en el tratamiento de la hemorragia cerebral. |
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2014
- 2014-09-16 AU AU2014326257A patent/AU2014326257B2/en not_active Ceased
- 2014-09-16 BR BR112016005899A patent/BR112016005899A8/pt not_active IP Right Cessation
- 2014-09-16 CN CN201480052212.2A patent/CN105579468A/zh active Pending
- 2014-09-16 RU RU2016108608A patent/RU2648144C2/ru active
- 2014-09-16 HK HK16106674.2A patent/HK1218760A1/zh unknown
- 2014-09-16 KR KR1020167007373A patent/KR101988705B1/ko not_active Expired - Fee Related
- 2014-09-16 CN CN202011112690.1A patent/CN112195169A/zh active Pending
- 2014-09-16 EP EP14792595.2A patent/EP3049434A1/en not_active Withdrawn
- 2014-09-16 MY MYPI2016700985A patent/MY173548A/en unknown
- 2014-09-16 PE PE2016000398A patent/PE20160877A1/es unknown
- 2014-09-16 MX MX2016003871A patent/MX373466B/es active IP Right Grant
- 2014-09-16 CA CA2924981A patent/CA2924981C/en not_active Expired - Fee Related
- 2014-09-16 SG SG11201601221XA patent/SG11201601221XA/en unknown
- 2014-09-16 JP JP2016543477A patent/JP6429885B2/ja not_active Expired - Fee Related
- 2014-09-16 WO PCT/IB2014/064564 patent/WO2015044836A1/en not_active Ceased
- 2014-09-23 AR ARP140103512A patent/AR097732A1/es unknown
- 2014-09-23 TW TW103132803A patent/TWI631134B/zh not_active IP Right Cessation
- 2014-09-24 US US14/495,478 patent/US9757434B2/en not_active Expired - Fee Related
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2016
- 2016-02-23 IL IL244258A patent/IL244258A0/en unknown
- 2016-03-17 SA SA516370751A patent/SA516370751B1/ar unknown
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2017
- 2017-08-04 US US15/669,340 patent/US10660946B2/en active Active
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2020
- 2020-05-25 US US16/882,598 patent/US20210106658A1/en not_active Abandoned
- 2020-12-13 IL IL279396A patent/IL279396A/en unknown
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| RU2396347C2 (ru) * | 2004-08-17 | 2010-08-10 | Ксл Бехринг Гмбх | Модифицированные витамин к-зависимые полипептиды |
| US20090175931A1 (en) * | 2005-11-15 | 2009-07-09 | Camire Rodney M | Compositions and methods for modulating hemostasis |
| WO2013049804A1 (en) * | 2011-09-30 | 2013-04-04 | The Children's Hospital Of Philadelphia | Compositions and methods for modulating hemostasis |
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Also Published As
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| BR112016005899A8 (pt) | 2018-02-06 |
| KR20160044034A (ko) | 2016-04-22 |
| CN105579468A (zh) | 2016-05-11 |
| US20150182604A1 (en) | 2015-07-02 |
| TWI631134B (zh) | 2018-08-01 |
| AU2014326257A1 (en) | 2016-03-10 |
| IL244258A0 (en) | 2016-04-21 |
| BR112016005899A2 (pt) | 2017-09-26 |
| TW201524996A (zh) | 2015-07-01 |
| JP6429885B2 (ja) | 2018-11-28 |
| AU2014326257B2 (en) | 2017-08-10 |
| KR101988705B1 (ko) | 2019-06-12 |
| EP3049434A1 (en) | 2016-08-03 |
| CA2924981A1 (en) | 2015-04-02 |
| WO2015044836A1 (en) | 2015-04-02 |
| US20170333535A1 (en) | 2017-11-23 |
| MX2016003871A (es) | 2016-08-04 |
| IL279396A (en) | 2021-01-31 |
| PE20160877A1 (es) | 2016-09-11 |
| MX373466B (es) | 2020-05-25 |
| CA2924981C (en) | 2020-03-31 |
| MY173548A (en) | 2020-02-04 |
| RU2016108608A (ru) | 2017-10-26 |
| CN112195169A (zh) | 2021-01-08 |
| SG11201601221XA (en) | 2016-04-28 |
| US20210106658A1 (en) | 2021-04-15 |
| AR097732A1 (es) | 2016-04-13 |
| HK1218760A1 (zh) | 2017-03-10 |
| JP2016535071A (ja) | 2016-11-10 |
| US9757434B2 (en) | 2017-09-12 |
| US10660946B2 (en) | 2020-05-26 |
| SA516370751B1 (ar) | 2018-04-05 |
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