RU2636460C2 - Системы и способы применения зависящего от вращения транскрипционного секвенирования - Google Patents

Системы и способы применения зависящего от вращения транскрипционного секвенирования Download PDF

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RU2636460C2
RU2636460C2 RU2013142965A RU2013142965A RU2636460C2 RU 2636460 C2 RU2636460 C2 RU 2636460C2 RU 2013142965 A RU2013142965 A RU 2013142965A RU 2013142965 A RU2013142965 A RU 2013142965A RU 2636460 C2 RU2636460 C2 RU 2636460C2
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nucleic acid
rna polymerase
interest
sequencing
rotation
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RU2013142965A
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RU2013142965A (ru
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Теофилос КОТСЕРОГЛОУ
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Ив Байомедикал, Инк.
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
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  • Wood Science & Technology (AREA)
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  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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RU2013142965A 2011-02-23 2012-02-23 Системы и способы применения зависящего от вращения транскрипционного секвенирования RU2636460C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161463850P 2011-02-23 2011-02-23
US61/463,850 2011-02-23
US201161574270P 2011-07-30 2011-07-30
US61/574,270 2011-07-30
PCT/US2012/026339 WO2012116191A1 (en) 2011-02-23 2012-02-23 Rotation-dependent transcriptional sequencing systems and methods of using

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RU2013142965A RU2013142965A (ru) 2015-03-27
RU2636460C2 true RU2636460C2 (ru) 2017-11-23

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US (2) US8574840B2 (cg-RX-API-DMAC10.html)
EP (1) EP2678444B1 (cg-RX-API-DMAC10.html)
JP (1) JP6018092B2 (cg-RX-API-DMAC10.html)
KR (1) KR101924665B1 (cg-RX-API-DMAC10.html)
CN (1) CN103534357B (cg-RX-API-DMAC10.html)
AU (1) AU2012220546B2 (cg-RX-API-DMAC10.html)
CA (1) CA2827880A1 (cg-RX-API-DMAC10.html)
RU (1) RU2636460C2 (cg-RX-API-DMAC10.html)
WO (1) WO2012116191A1 (cg-RX-API-DMAC10.html)

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AU2014218911B2 (en) * 2013-02-20 2018-07-12 Eve Biomedical, Inc. Methods and compositions for nanostructure-based nucleic acid sequencing
US20160309068A1 (en) * 2014-01-06 2016-10-20 The Regents Of The University Of California Spatial frequency domain imaging using custom patterns
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WO2016174271A1 (en) * 2015-04-30 2016-11-03 Curevac Ag Immobilized poly(n)polymerase
CN106991224A (zh) * 2017-03-27 2017-07-28 蔡彤� 一种芯片引线键合定位的建模方法及系统
US11499962B2 (en) 2017-11-17 2022-11-15 Ultima Genomics, Inc. Methods and systems for analyte detection and analysis
US10267790B1 (en) 2017-11-17 2019-04-23 Ultima Genomics, Inc. Systems for biological sample processing and analysis
US10885772B2 (en) * 2017-12-21 2021-01-05 Lumileds Llc Road lighting
US11798406B2 (en) * 2018-03-21 2023-10-24 Lumileds Llc Road lighting
US10704094B1 (en) 2018-11-14 2020-07-07 Element Biosciences, Inc. Multipart reagents having increased avidity for polymerase binding
US10512911B1 (en) 2018-12-07 2019-12-24 Ultima Genomics, Inc. Implementing barriers for controlled environments during sample processing and detection
US12239980B2 (en) 2018-12-07 2025-03-04 Ultima Genomics, Inc. Implementing barriers for controlled environments during sample processing and detection
US10852518B1 (en) 2019-03-14 2020-12-01 Ultima Genomics, Inc. Methods, devices, and systems for analyte detection and analysis
US10830703B1 (en) 2019-03-14 2020-11-10 Ultima Genomics, Inc. Methods, devices, and systems for analyte detection and analysis
US10900078B2 (en) 2019-03-14 2021-01-26 Ultima Genomics, Inc. Methods, devices, and systems for analyte detection and analysis
US11118223B2 (en) 2019-03-14 2021-09-14 Ultima Genomics, Inc. Methods, devices, and systems for analyte detection and analysis
WO2020210370A1 (en) * 2019-04-12 2020-10-15 Roche Sequencing Solutions, Inc. Nucleic acid sequencing by synthesis using magnetic sensor arrays
US11327073B2 (en) 2019-04-12 2022-05-10 Western Digital Technologies, Inc. Thermal sensor array for molecule detection and related detection schemes
US11609208B2 (en) 2019-04-12 2023-03-21 Western Digital Technologies, Inc. Devices and methods for molecule detection based on thermal stabilities of magnetic nanoparticles
US11112468B2 (en) 2019-04-12 2021-09-07 Western Digital Technologies, Inc. Magnetoresistive sensor array for molecule detection and related detection schemes
CN110376171B (zh) * 2019-07-15 2021-11-19 上海理工大学 应用于dPCR检测仪的透射式荧光检测成像系统
US11208682B2 (en) 2019-09-13 2021-12-28 Western Digital Technologies, Inc. Enhanced optical detection for nucleic acid sequencing using thermally-dependent fluorophore tags
US11408032B2 (en) * 2020-01-17 2022-08-09 Element Biosciences, Inc. Tube lens design for improved depth-of-field
WO2022084748A1 (en) * 2020-10-23 2022-04-28 Spindle Biotech, Inc. Compositions and methods for rna synthesis
CN119061125A (zh) 2021-07-21 2024-12-03 元素生物科学公司 用于核酸测序的方法
EP4627115A1 (en) 2022-11-29 2025-10-08 Element Biosciences, Inc. Flow cell devices and optical systems for nucleic acid sequencing

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US8574840B2 (en) 2013-11-05
KR101924665B1 (ko) 2018-12-03
AU2012220546B2 (en) 2017-02-23
CN103534357A (zh) 2014-01-22
RU2013142965A (ru) 2015-03-27
US20140162275A1 (en) 2014-06-12
EP2678444A1 (en) 2014-01-01
WO2012116191A1 (en) 2012-08-30
US20120214171A1 (en) 2012-08-23
CN103534357B (zh) 2016-05-18
KR20140089308A (ko) 2014-07-14
AU2012220546A1 (en) 2013-09-12
CA2827880A1 (en) 2012-08-30
HK1187959A1 (zh) 2014-04-17
JP2014506485A (ja) 2014-03-17
JP6018092B2 (ja) 2016-11-02
US9657343B2 (en) 2017-05-23
EP2678444B1 (en) 2016-02-17

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