RU2595717C2 - Производные трисахаридов и их применение в качестве адъювантов - Google Patents
Производные трисахаридов и их применение в качестве адъювантов Download PDFInfo
- Publication number
- RU2595717C2 RU2595717C2 RU2013100945/04A RU2013100945A RU2595717C2 RU 2595717 C2 RU2595717 C2 RU 2595717C2 RU 2013100945/04 A RU2013100945/04 A RU 2013100945/04A RU 2013100945 A RU2013100945 A RU 2013100945A RU 2595717 C2 RU2595717 C2 RU 2595717C2
- Authority
- RU
- Russia
- Prior art keywords
- trisaccharide
- acid ester
- groups
- fatty acid
- ester
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C07H13/06—Fatty acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10165707A EP2397484A1 (en) | 2010-06-11 | 2010-06-11 | Trisaccharide derivates, and their use as adjuvants |
| EP10165707.0 | 2010-06-11 | ||
| PCT/NL2011/050393 WO2011155822A1 (en) | 2010-06-11 | 2011-06-03 | Trisaccharide derivates, and their use as adjuvants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2013100945A RU2013100945A (ru) | 2014-07-20 |
| RU2595717C2 true RU2595717C2 (ru) | 2016-08-27 |
Family
ID=43734127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2013100945/04A RU2595717C2 (ru) | 2010-06-11 | 2011-06-03 | Производные трисахаридов и их применение в качестве адъювантов |
Country Status (25)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2397484A1 (en) * | 2010-06-11 | 2011-12-21 | Immunovo B.V. | Trisaccharide derivates, and their use as adjuvants |
| HRP20192113T1 (hr) | 2014-07-24 | 2020-02-21 | Litevax B.V. | Adjuvanti |
| KR20250052985A (ko) | 2023-10-11 | 2025-04-21 | 세종대학교산학협력단 | 삼당류의 제조방법 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4232150A (en) * | 1979-07-09 | 1980-11-04 | American Cyanamid Company | Oligosaccharide precursors to substituted O-α-D and O-β-D-multigalactopyranosyl and glucopyranosyl 1→4 and 1→6 galactopyranosyl 1→6α-D-glucopyranoses |
| WO1988006143A1 (en) * | 1987-02-11 | 1988-08-25 | Donmarn Limited | Anti-scaling compounds |
| EP1104767A1 (en) * | 1999-11-30 | 2001-06-06 | Stichting Dienst Landbouwkundig Onderzoek | Mono- and disaccharide derivatives containing both fatty acid ester and sulfate ester groups |
| EP1792607A1 (en) * | 2005-12-01 | 2007-06-06 | Wella Aktiengesellschaft | Use of di- or oligosaccharide polyester in hair styling products |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5543505A (en) * | 1993-03-15 | 1996-08-06 | Sloan-Kettering Institute For Cancer Research | Synthetic compounds which bind to H. pylori, and uses thereof |
| US6303120B1 (en) * | 1994-03-15 | 2001-10-16 | Memorial Sloan-Kettering Institute For Cancer Research | Synthesis of glycoconjugates of the lewis y epitope and uses thereof |
| US5708163A (en) * | 1994-03-15 | 1998-01-13 | Sloan-Kettering Institute Of Cancer Research | Synthesis of the breast tumor-associated antigen defined by monoclonalantibody MBRL and uses thereof |
| CZ297431B6 (cs) * | 1994-08-04 | 2006-12-13 | Quadrant Holdings Cambridge Limited | Prostredek obsahující dodávací systém pevné dávkypro prímou aplikaci v pevné forme a zpusob jeho výroby |
| BE1008978A5 (fr) | 1994-12-27 | 1996-10-01 | Solvay | Adjuvants pour vaccins. |
| US6517860B1 (en) * | 1996-12-31 | 2003-02-11 | Quadrant Holdings Cambridge, Ltd. | Methods and compositions for improved bioavailability of bioactive agents for mucosal delivery |
| US6352722B1 (en) * | 1997-12-23 | 2002-03-05 | Quadrant Holdings Cambridge Limited | Derivatized carbohydrates, compositions comprised thereof and methods of use thereof |
| JP3041799B1 (ja) * | 1998-09-29 | 2000-05-15 | 株式会社微生物化学研究所 | 新規なアジュバント及びそれを用いたワクチン |
| GB0124710D0 (en) * | 2001-10-15 | 2001-12-05 | Quadrant Healthcare Uk Ltd | Therapeutic composition |
| US9045516B2 (en) * | 2007-04-16 | 2015-06-02 | Suri Saranathan Iyer | Synthetic ligands for the differentiation of closely related toxins and pathogens |
| WO2009140683A1 (en) * | 2008-05-16 | 2009-11-19 | Research Foundation Of The City University Of New York | Living copolymer protein/peptide hybrids for biomedical applications |
| EP2392579B1 (en) * | 2009-02-02 | 2016-11-23 | Otsuka Chemical Co., Ltd. | Low-molecular polysulfated hyaluronic acid derivative and medicine containing same |
| EP2397484A1 (en) * | 2010-06-11 | 2011-12-21 | Immunovo B.V. | Trisaccharide derivates, and their use as adjuvants |
-
2010
- 2010-06-11 EP EP10165707A patent/EP2397484A1/en not_active Withdrawn
-
2011
- 2011-06-03 PT PT117252171T patent/PT2580226T/pt unknown
- 2011-06-03 NO NO11725217A patent/NO2580226T3/no unknown
- 2011-06-03 CN CN201180034937.5A patent/CN103154013B/zh not_active Expired - Fee Related
- 2011-06-03 HU HUE11725217A patent/HUE035187T2/hu unknown
- 2011-06-03 ES ES11725217.1T patent/ES2654156T3/es active Active
- 2011-06-03 DK DK11725217.1T patent/DK2580226T3/en active
- 2011-06-03 SI SI201131368T patent/SI2580226T1/en unknown
- 2011-06-03 HR HRP20171947TT patent/HRP20171947T1/hr unknown
- 2011-06-03 PL PL11725217T patent/PL2580226T3/pl unknown
- 2011-06-03 BR BR112012031440A patent/BR112012031440A2/pt not_active Application Discontinuation
- 2011-06-03 JP JP2013514126A patent/JP6004586B2/ja not_active Expired - Fee Related
- 2011-06-03 SM SM20170603T patent/SMT201700603T1/it unknown
- 2011-06-03 LT LTEP11725217.1T patent/LT2580226T/lt unknown
- 2011-06-03 KR KR1020137000623A patent/KR101929973B1/ko not_active Expired - Fee Related
- 2011-06-03 CA CA2802023A patent/CA2802023C/en not_active Expired - Fee Related
- 2011-06-03 AU AU2011262606A patent/AU2011262606B2/en not_active Ceased
- 2011-06-03 US US13/703,329 patent/US9327020B2/en not_active Expired - Fee Related
- 2011-06-03 WO PCT/NL2011/050393 patent/WO2011155822A1/en not_active Ceased
- 2011-06-03 RS RS20171307A patent/RS56690B1/sr unknown
- 2011-06-03 RU RU2013100945/04A patent/RU2595717C2/ru active
- 2011-06-03 MX MX2012014422A patent/MX342946B/es active IP Right Grant
- 2011-06-03 EP EP17204140.2A patent/EP3312188A1/en not_active Withdrawn
- 2011-06-03 EP EP11725217.1A patent/EP2580226B1/en active Active
-
2012
- 2012-12-11 IL IL223570A patent/IL223570A/en active IP Right Grant
- 2012-12-11 ZA ZA2012/09395A patent/ZA201209395B/en unknown
-
2016
- 2016-04-05 US US15/090,853 patent/US20170057987A1/en not_active Abandoned
- 2016-06-15 JP JP2016119032A patent/JP2016216471A/ja active Pending
-
2017
- 2017-12-21 CY CY20171101340T patent/CY1119704T1/el unknown
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4232150A (en) * | 1979-07-09 | 1980-11-04 | American Cyanamid Company | Oligosaccharide precursors to substituted O-α-D and O-β-D-multigalactopyranosyl and glucopyranosyl 1→4 and 1→6 galactopyranosyl 1→6α-D-glucopyranoses |
| WO1988006143A1 (en) * | 1987-02-11 | 1988-08-25 | Donmarn Limited | Anti-scaling compounds |
| EP1104767A1 (en) * | 1999-11-30 | 2001-06-06 | Stichting Dienst Landbouwkundig Onderzoek | Mono- and disaccharide derivatives containing both fatty acid ester and sulfate ester groups |
| EP1792607A1 (en) * | 2005-12-01 | 2007-06-06 | Wella Aktiengesellschaft | Use of di- or oligosaccharide polyester in hair styling products |
Non-Patent Citations (1)
| Title |
|---|
| Yag G. et al, Organic Letters, 2006, vol. 8, N6, 911-914. P. Arndt et al, Cellulose, Kluwer Academic publishers, DO, 2005, vol. 12, N3, 317-326. Casmir C. Akoh et al, Journal of Food Science, 1987, vol. 52, N6, 1570-1575. Mogemark M et al, Organic & Biomolecular Chemistry, 2003, vol. 1, 2003, 2063-2069. * |
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