RU2587329C2 - Лекарственная комбинация с теобромином и ее использование в лечении - Google Patents

Лекарственная комбинация с теобромином и ее использование в лечении Download PDF

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Publication number
RU2587329C2
RU2587329C2 RU2012124063/15A RU2012124063A RU2587329C2 RU 2587329 C2 RU2587329 C2 RU 2587329C2 RU 2012124063/15 A RU2012124063/15 A RU 2012124063/15A RU 2012124063 A RU2012124063 A RU 2012124063A RU 2587329 C2 RU2587329 C2 RU 2587329C2
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RU
Russia
Prior art keywords
cough
codeine
theobromine
treatment
combination
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RU2012124063/15A
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English (en)
Russian (ru)
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RU2012124063A (ru
Inventor
Джон Брю
Робин Марк Баннистер
Original Assignee
ИнФёрст Хэлткэр Лимитед
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Application filed by ИнФёрст Хэлткэр Лимитед filed Critical ИнФёрст Хэлткэр Лимитед
Publication of RU2012124063A publication Critical patent/RU2012124063A/ru
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Publication of RU2587329C2 publication Critical patent/RU2587329C2/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
RU2012124063/15A 2009-11-13 2010-11-12 Лекарственная комбинация с теобромином и ее использование в лечении RU2587329C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0919893.8A GB0919893D0 (en) 2009-11-13 2009-11-13 Drug composition and its use in therapy
GB0919893.8 2009-11-13
PCT/GB2010/051896 WO2011058374A1 (en) 2009-11-13 2010-11-12 Drug combination with theobromine and its use in therapy

Publications (2)

Publication Number Publication Date
RU2012124063A RU2012124063A (ru) 2013-12-20
RU2587329C2 true RU2587329C2 (ru) 2016-06-20

Family

ID=41509327

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2012124063/15A RU2587329C2 (ru) 2009-11-13 2010-11-12 Лекарственная комбинация с теобромином и ее использование в лечении

Country Status (18)

Country Link
EP (1) EP2498776A1 (uk)
JP (2) JP2013510842A (uk)
CN (1) CN102740853B (uk)
AU (1) AU2010317668C1 (uk)
BR (1) BR112012011224A2 (uk)
CA (1) CA2780704C (uk)
CO (1) CO6551745A2 (uk)
EC (2) ECSP12011892A (uk)
GB (1) GB0919893D0 (uk)
IL (1) IL219769A0 (uk)
MX (1) MX2012005538A (uk)
NZ (1) NZ599957A (uk)
PE (1) PE20121472A1 (uk)
RU (1) RU2587329C2 (uk)
SG (1) SG10201407496SA (uk)
UA (1) UA105940C2 (uk)
WO (1) WO2011058374A1 (uk)
ZA (1) ZA201204247B (uk)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2805751C2 (ru) * 2022-03-01 2023-10-23 Федеральное государственное бюджетное образовательное учреждение высшего образования "Самарский государственный медицинский университет" Министерства здравоохранения Российской Федерации Со-кристаллические формы теобромина

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0910375D0 (en) 2009-06-16 2009-07-29 Biocopea Ltd Drug composition and its use in therapy
US9308211B2 (en) 2009-06-16 2016-04-12 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
US9314465B2 (en) 2009-06-16 2016-04-19 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
US10016437B2 (en) 2009-06-16 2018-07-10 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB201111485D0 (en) * 2011-07-05 2011-08-17 Biocopea Ltd Drug composition and its use in therapy

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2362559C2 (ru) * 2003-02-28 2009-07-27 ЙЭм БАЙОСАЙЕНСИЗ ИНК. Система доставки опиоидов

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AU2523588A (en) * 1987-10-08 1989-05-02 Andor Bilas Mixture of substances for stabilyzing metabolism
BR9407414A (pt) * 1993-09-07 1996-11-12 Procter & Gamble Composições contendo um sal de aminoácido de agente antiinflamatório não-esteroide de ácido propiônico e pelo menos um descongestionante um expectorante um anti-histamina e um antitussivo
HUP9700654A2 (hu) * 1997-03-26 1999-09-28 Dezső Korbonits Teobromin tartalmú köhögéscsillapító készítmények
US6608073B1 (en) * 1998-10-14 2003-08-19 New Millennium Pharmaceutical Research, Inc. Intranasal codeine for the rapid suppression of cough and rapid relief of pain
HUP9802716A3 (en) * 1998-11-25 2000-08-28 Chinoin Gyogyszer Es Vegyeszet Pharmaceutical composition of analgesic activity
DK1465634T3 (da) * 2001-12-12 2015-01-26 Us Government Fremgangsmåde til anvendelse af adenosinreceptorinhibitorer til at forstærke immunrespons og inflammation
CN1593451A (zh) * 2003-09-12 2005-03-16 杨喜鸿 促进男性勃起的外用药物
WO2006064780A1 (ja) * 2004-12-14 2006-06-22 Shionogi & Co., Ltd. 便秘治療剤
US20080003280A1 (en) * 2006-06-26 2008-01-03 Levine Brian M Combination cough treatment compounds and method of treating common coughs
KR20080009994A (ko) * 2006-07-25 2008-01-30 안국약품 주식회사 기침 치료용 조성물

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2362559C2 (ru) * 2003-02-28 2009-07-27 ЙЭм БАЙОСАЙЕНСИЗ ИНК. Система доставки опиоидов

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ANTONIADES N. et al. Topical lidocaine through the bronchoscope cough rate during bronchoscopy. Respirology 2009 Aug; 14(6): 873-6 Реферат [он-лайн] [найдено 24.10.2014] (Найдено из Интернет:www.ncbi.nlm.nih.gov/pubmed/19703068). USMANI OS et al. Theobromine inhibits sensory nerve activation and cough.FASEB J. 2005 Feb;19(2):231-3 [он-лайн] [найдено 24.10.2014] (Найдено из Интернет:www.ncbi.nlm.nih.gov/pubmed/15548587). И.Б.МИХАЙЛОВ Настольная книга врача по клинической фармакологии СП-Б Фолиант 2001 с.513 глава 17.3 раздел Синтетические заменители морфина. ЭНЦИКЛОПЕДИЯ ЛЕКАРСТВ М., РЛС 2001 8-е изд с.431 статья кодеин, с.496 статья Лоперамид. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2805751C2 (ru) * 2022-03-01 2023-10-23 Федеральное государственное бюджетное образовательное учреждение высшего образования "Самарский государственный медицинский университет" Министерства здравоохранения Российской Федерации Со-кристаллические формы теобромина

Also Published As

Publication number Publication date
CN102740853B (zh) 2015-04-08
PE20121472A1 (es) 2012-11-30
EP2498776A1 (en) 2012-09-19
RU2012124063A (ru) 2013-12-20
WO2011058374A1 (en) 2011-05-19
ECSP12011893A (es) 2012-10-30
UA105940C2 (uk) 2014-07-10
BR112012011224A2 (pt) 2017-03-01
AU2010317668C1 (en) 2016-02-11
CA2780704A1 (en) 2011-05-19
CA2780704C (en) 2018-07-17
JP2016041748A (ja) 2016-03-31
ZA201204247B (en) 2013-02-27
CN102740853A (zh) 2012-10-17
GB0919893D0 (en) 2009-12-30
MX2012005538A (es) 2012-09-28
NZ599957A (en) 2014-05-30
AU2010317668A1 (en) 2012-06-07
ECSP12011892A (es) 2012-09-28
IL219769A0 (en) 2012-07-31
SG10201407496SA (en) 2015-02-27
JP2013510842A (ja) 2013-03-28
AU2010317668B2 (en) 2015-01-22
CO6551745A2 (es) 2012-10-31

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20171113