CA2780704C - Drug combination with theobromine and its use in therapy - Google Patents

Drug combination with theobromine and its use in therapy Download PDF

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Publication number
CA2780704C
CA2780704C CA2780704A CA2780704A CA2780704C CA 2780704 C CA2780704 C CA 2780704C CA 2780704 A CA2780704 A CA 2780704A CA 2780704 A CA2780704 A CA 2780704A CA 2780704 C CA2780704 C CA 2780704C
Authority
CA
Canada
Prior art keywords
opiate
composition
codeine
day
theobromine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2780704A
Other languages
English (en)
French (fr)
Other versions
CA2780704A1 (en
Inventor
John Brew
Robin Mark Bannister
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Infirst Healthcare Ltd
Original Assignee
Infirst Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Infirst Healthcare Ltd filed Critical Infirst Healthcare Ltd
Publication of CA2780704A1 publication Critical patent/CA2780704A1/en
Application granted granted Critical
Publication of CA2780704C publication Critical patent/CA2780704C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CA2780704A 2009-11-13 2010-11-12 Drug combination with theobromine and its use in therapy Expired - Fee Related CA2780704C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0919893.8A GB0919893D0 (en) 2009-11-13 2009-11-13 Drug composition and its use in therapy
GB0919893.8 2009-11-13
PCT/GB2010/051896 WO2011058374A1 (en) 2009-11-13 2010-11-12 Drug combination with theobromine and its use in therapy

Publications (2)

Publication Number Publication Date
CA2780704A1 CA2780704A1 (en) 2011-05-19
CA2780704C true CA2780704C (en) 2018-07-17

Family

ID=41509327

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2780704A Expired - Fee Related CA2780704C (en) 2009-11-13 2010-11-12 Drug combination with theobromine and its use in therapy

Country Status (18)

Country Link
EP (1) EP2498776A1 (uk)
JP (2) JP2013510842A (uk)
CN (1) CN102740853B (uk)
AU (1) AU2010317668C1 (uk)
BR (1) BR112012011224A2 (uk)
CA (1) CA2780704C (uk)
CO (1) CO6551745A2 (uk)
EC (2) ECSP12011892A (uk)
GB (1) GB0919893D0 (uk)
IL (1) IL219769A0 (uk)
MX (1) MX2012005538A (uk)
NZ (1) NZ599957A (uk)
PE (1) PE20121472A1 (uk)
RU (1) RU2587329C2 (uk)
SG (1) SG10201407496SA (uk)
UA (1) UA105940C2 (uk)
WO (1) WO2011058374A1 (uk)
ZA (1) ZA201204247B (uk)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0910375D0 (en) 2009-06-16 2009-07-29 Biocopea Ltd Drug composition and its use in therapy
US9308211B2 (en) 2009-06-16 2016-04-12 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
US9314465B2 (en) 2009-06-16 2016-04-19 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
US10016437B2 (en) 2009-06-16 2018-07-10 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB201111485D0 (en) * 2011-07-05 2011-08-17 Biocopea Ltd Drug composition and its use in therapy

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2523588A (en) * 1987-10-08 1989-05-02 Andor Bilas Mixture of substances for stabilyzing metabolism
BR9407414A (pt) * 1993-09-07 1996-11-12 Procter & Gamble Composições contendo um sal de aminoácido de agente antiinflamatório não-esteroide de ácido propiônico e pelo menos um descongestionante um expectorante um anti-histamina e um antitussivo
HUP9700654A2 (hu) * 1997-03-26 1999-09-28 Dezső Korbonits Teobromin tartalmú köhögéscsillapító készítmények
US6608073B1 (en) * 1998-10-14 2003-08-19 New Millennium Pharmaceutical Research, Inc. Intranasal codeine for the rapid suppression of cough and rapid relief of pain
HUP9802716A3 (en) * 1998-11-25 2000-08-28 Chinoin Gyogyszer Es Vegyeszet Pharmaceutical composition of analgesic activity
DK1465634T3 (da) * 2001-12-12 2015-01-26 Us Government Fremgangsmåde til anvendelse af adenosinreceptorinhibitorer til at forstærke immunrespons og inflammation
PT1603533E (pt) * 2003-02-28 2009-07-23 Ym Biosciences Inc Sistema de administração de opióides
CN1593451A (zh) * 2003-09-12 2005-03-16 杨喜鸿 促进男性勃起的外用药物
WO2006064780A1 (ja) * 2004-12-14 2006-06-22 Shionogi & Co., Ltd. 便秘治療剤
US20080003280A1 (en) * 2006-06-26 2008-01-03 Levine Brian M Combination cough treatment compounds and method of treating common coughs
KR20080009994A (ko) * 2006-07-25 2008-01-30 안국약품 주식회사 기침 치료용 조성물

Also Published As

Publication number Publication date
CN102740853B (zh) 2015-04-08
PE20121472A1 (es) 2012-11-30
EP2498776A1 (en) 2012-09-19
RU2012124063A (ru) 2013-12-20
WO2011058374A1 (en) 2011-05-19
ECSP12011893A (es) 2012-10-30
UA105940C2 (uk) 2014-07-10
RU2587329C2 (ru) 2016-06-20
BR112012011224A2 (pt) 2017-03-01
AU2010317668C1 (en) 2016-02-11
CA2780704A1 (en) 2011-05-19
JP2016041748A (ja) 2016-03-31
ZA201204247B (en) 2013-02-27
CN102740853A (zh) 2012-10-17
GB0919893D0 (en) 2009-12-30
MX2012005538A (es) 2012-09-28
NZ599957A (en) 2014-05-30
AU2010317668A1 (en) 2012-06-07
ECSP12011892A (es) 2012-09-28
IL219769A0 (en) 2012-07-31
SG10201407496SA (en) 2015-02-27
JP2013510842A (ja) 2013-03-28
AU2010317668B2 (en) 2015-01-22
CO6551745A2 (es) 2012-10-31

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20151105

MKLA Lapsed

Effective date: 20191112