RU2560431C2 - Пептиды foxm1 и вакцины, содержащие их - Google Patents

Пептиды foxm1 и вакцины, содержащие их Download PDF

Info

Publication number
RU2560431C2
RU2560431C2 RU2011138160/10A RU2011138160A RU2560431C2 RU 2560431 C2 RU2560431 C2 RU 2560431C2 RU 2011138160/10 A RU2011138160/10 A RU 2011138160/10A RU 2011138160 A RU2011138160 A RU 2011138160A RU 2560431 C2 RU2560431 C2 RU 2560431C2
Authority
RU
Russia
Prior art keywords
cancer
present
foxm1
peptides
peptide
Prior art date
Application number
RU2011138160/10A
Other languages
English (en)
Russian (ru)
Other versions
RU2011138160A (ru
Inventor
Такуя Цунода
Рюдзи Осава
Сатико Йосимура
Томохиса Ватанабе
Original Assignee
Онкотерапи Сайенс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Онкотерапи Сайенс, Инк. filed Critical Онкотерапи Сайенс, Инк.
Publication of RU2011138160A publication Critical patent/RU2011138160A/ru
Application granted granted Critical
Publication of RU2560431C2 publication Critical patent/RU2560431C2/ru

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4242—Transcription factors, e.g. SOX or c-MYC
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
RU2011138160/10A 2009-02-18 2010-02-17 Пептиды foxm1 и вакцины, содержащие их RU2560431C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15340809P 2009-02-18 2009-02-18
US61/153,408 2009-02-18
PCT/JP2010/001005 WO2010095428A1 (en) 2009-02-18 2010-02-17 Foxm1 peptides and vaccines containing the same

Publications (2)

Publication Number Publication Date
RU2011138160A RU2011138160A (ru) 2013-03-27
RU2560431C2 true RU2560431C2 (ru) 2015-08-20

Family

ID=42633716

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2011138160/10A RU2560431C2 (ru) 2009-02-18 2010-02-17 Пептиды foxm1 и вакцины, содержащие их

Country Status (15)

Country Link
US (1) US8617562B2 (https=)
EP (1) EP2408912B1 (https=)
JP (1) JP5728717B2 (https=)
KR (1) KR101713586B1 (https=)
CN (1) CN102405285B (https=)
BR (1) BRPI1008887A2 (https=)
CA (1) CA2752560C (https=)
DK (1) DK2408912T3 (https=)
ES (1) ES2618896T3 (https=)
IL (1) IL214435A0 (https=)
MX (1) MX2011008763A (https=)
RU (1) RU2560431C2 (https=)
SG (1) SG173751A1 (https=)
TW (1) TWI469791B (https=)
WO (1) WO2010095428A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12195559B2 (en) 2018-08-02 2025-01-14 Oncotherapy Science, Inc. CDCA1-derived peptide and vaccine containing same

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8569244B2 (en) 2007-08-20 2013-10-29 Oncotherapy Science, Inc. FOXM1 peptide and medicinal agent comprising the same
US20150359864A1 (en) 2012-03-09 2015-12-17 Oncotherapy Science, Inc. Pharmaceutical composition containing peptides
GB201410686D0 (en) * 2014-06-16 2014-07-30 Immunocore Ltd & Adaptimmune Ltd Peptides
BR112018005581A2 (pt) 2015-10-08 2018-10-16 Oncotherapy Science, Inc. peptídeo derivado de foxm1 e vacina incluindo o mesmo
CN105524159B (zh) * 2015-11-16 2021-04-09 西南交通大学 具有癌细胞选择性杀伤和迁移抑制作用的多肽分子与用途
CN105999227B (zh) * 2016-08-12 2019-08-06 湖南大学 FOXM1蛋白氮端（1-234 aa）的表达及其用途
JP2020503840A (ja) 2016-10-07 2020-02-06 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム Ｈｌａ拘束性ｖｇｌｌ１ペプチドおよびその使用
EP3691662A4 (en) * 2017-10-06 2021-05-12 The University of Chicago SCREENING OF T LYMPHOCYTE FOR CANCER SPECIFIC ANTIGENS
HRP20230007T1 (hr) * 2018-04-11 2023-03-03 Enterome S.A. Antigenski peptidi, namijenjeni sprječavanju i liječenju raka
CN109055327B (zh) * 2018-07-23 2021-04-06 浙江工业大学 醛酮还原酶突变体及其应用
AU2021275239A1 (en) 2020-05-21 2022-12-15 Board Of Regents, The University Of Texas System T cell receptors with VGLL1 specificity and uses thereof
CN114591400B (zh) * 2022-03-29 2022-10-21 西南交通大学 一组靶向FoxM1-DBD多肽及其应用

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4722848A (en) 1982-12-08 1988-02-02 Health Research, Incorporated Method for immunizing animals with synthetically modified vaccinia virus
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5804566A (en) 1993-08-26 1998-09-08 The Regents Of The University Of California Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides
US5679647A (en) 1993-08-26 1997-10-21 The Regents Of The University Of California Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides
US5739118A (en) 1994-04-01 1998-04-14 Apollon, Inc. Compositions and methods for delivery of genetic material
US5736524A (en) 1994-11-14 1998-04-07 Merck & Co.,. Inc. Polynucleotide tuberculosis vaccine
US5922687A (en) 1995-05-04 1999-07-13 Board Of Trustees Of The Leland Stanford Junior University Intracellular delivery of nucleic acids using pressure
WO1997005900A1 (en) 1995-08-03 1997-02-20 Rijksuniversiteit Te Leiden Cell derived antigen presenting vesicles
US5853719A (en) 1996-04-30 1998-12-29 Duke University Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA
JP2000516090A (ja) 1996-07-26 2000-12-05 スローン―ケッタリング インスティチュート フォー キャンサー リサーチ 遺伝子的免疫化のための方法と試薬
US5861278A (en) 1996-11-01 1999-01-19 Genetics Institute, Inc. HNF3δ compositions
EP0846761A1 (en) * 1996-12-09 1998-06-10 Introgene B.V. A novel transcription factor expressed in cycling cells, nucleic acid molecules encoding said transcription factor and its promoter region and uses thereof
FR2766205B1 (fr) 1997-07-16 2002-08-30 Inst Nat Sante Rech Med Nouveau procede de sensibilisation de cellules presentatrices d'antigene et nouveaux moyens pour la mise en oeuvre du procede
US6747137B1 (en) 1998-02-13 2004-06-08 Genome Therapeutics Corporation Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics
JP4413429B2 (ja) 1998-06-25 2010-02-10 株式会社グリーンペプタイド サイクロフィリンｂ由来の腫瘍抗原ペプチド
US20030235557A1 (en) 1998-09-30 2003-12-25 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
WO2002099076A2 (en) 2001-06-04 2002-12-12 Basf Plant Science Gmbh Sugar and lipid metabolism regulators in plants ii
US20040142325A1 (en) 2001-09-14 2004-07-22 Liat Mintz Methods and systems for annotating biomolecular sequences
AU2002349543A1 (en) 2001-12-10 2003-06-23 Kyogo Itoh Tumor antigens
WO2004019761A2 (en) * 2002-08-28 2004-03-11 The Board Of Trustees Of The University Of Illinois Methods of treating age-related defects and diseases
JP4679149B2 (ja) 2002-09-30 2011-04-27 オンコセラピー・サイエンス株式会社 ヒト膵癌に関連する遺伝子およびポリペプチド
US20060024692A1 (en) 2002-09-30 2006-02-02 Oncotherapy Science, Inc. Method for diagnosing non-small cell lung cancers
TW200413725A (en) 2002-09-30 2004-08-01 Oncotherapy Science Inc Method for diagnosing non-small cell lung cancers
US20050260639A1 (en) 2002-09-30 2005-11-24 Oncotherapy Science, Inc. Method for diagnosing pancreatic cancer
US7635673B2 (en) 2003-03-25 2009-12-22 The Board Of Trustees Of The University Of Illinois Methods of inhibiting tumor cell proliferation
WO2005029067A2 (en) 2003-09-24 2005-03-31 Oncotherapy Science, Inc. Method of diagnosing breast cancer
EP1697399B1 (en) 2003-12-12 2016-11-23 GOVERNMENT OF THE UNITED STATES OF AMERICA, as repr. by THE SECR. OF THE DEPT. OF HEALTH AND HUMAN SERVICES AND HIS SUCCESSORS A human cytotoxic t-lymphocyte epitope and its agonist epitope from the non-variable number of tandem repeat sequence of muc-1
CA2555145A1 (en) 2004-02-06 2005-08-25 Wyeth Diagnosis and therapeutics for cancer
US7700573B2 (en) 2004-03-23 2010-04-20 Oncotherapy Science, Inc. Method for diagnosing non-small lung cancer
EP1730533A1 (en) 2004-03-24 2006-12-13 Oncotherapy Science, Inc. Adam8 as tumor marker and therapeutic target for non-small cell lung cancer
WO2006031221A1 (en) 2004-09-13 2006-03-23 Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Compositions comprising t cell receptors and methods of use thereof
JP2006141208A (ja) 2004-11-16 2006-06-08 Univ Of Tokushima 多発性骨髄腫、白血病、悪性リンパ腫、肺癌等の免疫療法剤
CN101175862A (zh) 2005-02-10 2008-05-07 肿瘤疗法科学股份有限公司 诊断膀胱癌的方法
EP2295570A1 (en) 2005-07-27 2011-03-16 Oncotherapy Science, Inc. Method of diagnosing small cell lung cancer
EP2311985A1 (en) 2005-07-27 2011-04-20 Oncotherapy Science, Inc. Sirna for treating esophageal cancer
JP5276846B2 (ja) 2005-09-13 2013-08-28 国立大学法人三重大学 Ｔ細胞レセプターをコードする核酸が挿入されてなるベクター及び該レセプターを発現する細胞
EP1806413A1 (en) 2006-01-06 2007-07-11 Oligene GmbH An in-vitro-method and means for determination of different tumor types and predicting success of surgical procedures in ovarian cancer
JP2009536516A (ja) 2006-04-20 2009-10-15 オンコセラピー・サイエンス株式会社 肺癌の治療標的としてのＮＭＵ−ＧＨＳＲ１ｂ／ＮＴＳＲ１発癌シグナル伝達経路
PT2186889E (pt) 2007-08-20 2015-06-17 Oncotherapy Science Inc Péptido cdca1 e agente farmacêutico que o compreende
US8569244B2 (en) 2007-08-20 2013-10-29 Oncotherapy Science, Inc. FOXM1 peptide and medicinal agent comprising the same
ES2617434T3 (es) 2009-03-18 2017-06-19 Oncotherapy Science, Inc. Péptidos NEIL3 y vacunas que incluyen los mismos

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
LAOUKILI J. et al., "FoxM1: At the crossroads of ageing and cancer", Biochimica et Biophysica Acta, 2007 (available online 30 August 2006); 1775: 92"102. KIM I.-M. et al., "The Forkhead Box m1 Transcription Factor Stimulates the Proliferation of Tumor Cells during Development of Lung Cancer", Cancer Res 2006 (published online 17 February 2006); 66:2153-2161. KOMORI H. et al. "Identification of HLA-A2- or HLA-A24-Restricted CTL Epitopes Possibly Useful for Glypican-3-Specific Immunotherapy of Hepatocellular Carcinoma", Clin Cancer Res, 2006; 12: 2689-2697. АБЕЛЕВ Г.И., "Иммунология опухолей человека", Природа, 2000; 2:20-25 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12195559B2 (en) 2018-08-02 2025-01-14 Oncotherapy Science, Inc. CDCA1-derived peptide and vaccine containing same

Also Published As

Publication number Publication date
US8617562B2 (en) 2013-12-31
CN102405285B (zh) 2015-04-22
KR101713586B1 (ko) 2017-03-08
US20120156231A1 (en) 2012-06-21
IL214435A0 (en) 2011-09-27
TW201032821A (en) 2010-09-16
BRPI1008887A2 (pt) 2016-03-01
CA2752560A1 (en) 2010-08-26
CN102405285A (zh) 2012-04-04
ES2618896T3 (es) 2017-06-22
SG173751A1 (en) 2011-09-29
AU2010216980A1 (en) 2011-08-25
TWI469791B (zh) 2015-01-21
RU2011138160A (ru) 2013-03-27
MX2011008763A (es) 2011-09-09
EP2408912B1 (en) 2017-01-18
CA2752560C (en) 2017-01-24
KR20110117241A (ko) 2011-10-26
WO2010095428A1 (en) 2010-08-26
EP2408912A4 (en) 2013-04-17
DK2408912T3 (en) 2017-03-20
JP5728717B2 (ja) 2015-06-03
EP2408912A1 (en) 2012-01-25
JP2012517799A (ja) 2012-08-09

Similar Documents

Publication Publication Date Title
RU2560431C2 (ru) Пептиды foxm1 и вакцины, содержащие их
RU2550695C2 (ru) Олигопептиды imp-3 и содержащие их вакцины
JP5564730B2 (ja) Ｍｐｈｏｓｐｈ１ペプチドおよびそれを含むワクチン
US20140199335A1 (en) C1orf59 peptides and vaccines including the same
RU2514386C2 (ru) Пептиды эпитопа wdrpuh и вакцины, содержащие их
WO2010070877A1 (en) Elovl7 epitope peptides and vaccines containing the same
AU2010216980B2 (en) FOXM1 peptides and vaccines containing the same
HK1165460B (en) Foxm1 peptides and vaccines containing the same
HK1165460A (en) Foxm1 peptides and vaccines containing the same

Legal Events

Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20180218