RU2531348C2 - Пептиды ттк и вакцины, их содержащие - Google Patents
Пептиды ттк и вакцины, их содержащие Download PDFInfo
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- RU2531348C2 RU2531348C2 RU2011150283/04A RU2011150283A RU2531348C2 RU 2531348 C2 RU2531348 C2 RU 2531348C2 RU 2011150283/04 A RU2011150283/04 A RU 2011150283/04A RU 2011150283 A RU2011150283 A RU 2011150283A RU 2531348 C2 RU2531348 C2 RU 2531348C2
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Classifications
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- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Molecular Biology (AREA)
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- Veterinary Medicine (AREA)
- Public Health (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Plant Pathology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21601709P | 2009-05-11 | 2009-05-11 | |
| US61/216,017 | 2009-05-11 | ||
| PCT/JP2010/003166 WO2010131452A1 (en) | 2009-05-11 | 2010-05-10 | Ttk peptides and vaccines including the same |
Publications (2)
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|---|---|
| RU2011150283A RU2011150283A (ru) | 2013-06-20 |
| RU2531348C2 true RU2531348C2 (ru) | 2014-10-20 |
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| EP (1) | EP2430039A4 (enExample) |
| JP (1) | JP5786178B2 (enExample) |
| KR (1) | KR20120029394A (enExample) |
| CN (1) | CN102459314B (enExample) |
| AU (1) | AU2010248702A1 (enExample) |
| BR (1) | BRPI1013938A2 (enExample) |
| CA (1) | CA2761393A1 (enExample) |
| MX (1) | MX2011012013A (enExample) |
| RU (1) | RU2531348C2 (enExample) |
| SG (1) | SG175998A1 (enExample) |
| TW (1) | TW201102081A (enExample) |
| WO (1) | WO2010131452A1 (enExample) |
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| US10092634B2 (en) * | 2012-09-11 | 2018-10-09 | Oncotherapy Science, Inc. | UBE2T peptides and vaccines containing the same |
| WO2018090257A1 (zh) * | 2016-11-16 | 2018-05-24 | 深圳华大基因研究院 | 多肽及其应用 |
| WO2018098636A1 (zh) * | 2016-11-29 | 2018-06-07 | 深圳华大基因研究院 | 多肽及其应用 |
| ES2940087T3 (es) * | 2017-07-12 | 2023-05-03 | Nouscom Ag | Una vacuna universal basada en neoantígenos tumorales compartidos para la prevención y el tratamiento de cánceres con inestabilidad microsatelital (MSI) |
| CN120712104A (zh) * | 2022-10-14 | 2025-09-26 | 广东天科雅生物医药科技有限公司 | 针对神经胶质瘤的肽疫苗及其用途 |
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| RU2464275C2 (ru) * | 2007-02-21 | 2012-10-20 | Онкотерапи Сайенс, Инк. | Пептидные вакцины для раков, экспрессирующих опухолеспецифические антигены |
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| US6187548B1 (en) * | 1993-05-23 | 2001-02-13 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Methods using human calcium sensor protein, fragments thereof and DNA encoding same |
| US20030045491A1 (en) | 2001-02-23 | 2003-03-06 | Christoph Reinhard | TTK in diagnosis and as a therapeutic target in cancer |
| ATE553112T1 (de) | 2001-02-21 | 2012-04-15 | Novartis Vaccines & Diagnostic | Ttk in der diagnose und als therapeutisches target bei krebs |
| US7501243B2 (en) * | 2001-02-21 | 2009-03-10 | Novartis Vaccines And Diagnostics, Inc. | Detection of colon or breast cancer by measuring TTK polypeptide expression |
| JP2005527180A (ja) | 2001-04-18 | 2005-09-15 | プロテイン デザイン ラブス， インコーポレイテッド | 肺がんの診断方法、肺がんの修飾因子の組成及びスクリーニングの方法 |
| WO2003073374A2 (en) * | 2002-02-27 | 2003-09-04 | Brands Michael Rik Frans | A data integration and knowledge management solution |
| TW200413725A (en) | 2002-09-30 | 2004-08-01 | Oncotherapy Science Inc | Method for diagnosing non-small cell lung cancers |
| US20060024692A1 (en) | 2002-09-30 | 2006-02-02 | Oncotherapy Science, Inc. | Method for diagnosing non-small cell lung cancers |
| CA2511907A1 (en) | 2003-01-06 | 2004-07-22 | Wyeth | Compositions and methods for diagnosing and treating colon cancers |
| WO2004070062A2 (en) | 2003-02-04 | 2004-08-19 | Wyeth | Compositions and methods for diagnosing and treating cancers |
| AU2003224132A1 (en) | 2003-04-24 | 2004-11-19 | Galapagos Genomics N.V. | Effective sirna knock-down constructs |
| US20050181385A1 (en) | 2003-09-22 | 2005-08-18 | Linsley Peter S. | Synthetic lethal screen using RNA interference |
| WO2005073374A1 (ja) * | 2004-01-29 | 2005-08-11 | Dainippon Sumitomo Pharma Co., Ltd. | 新規腫瘍抗原蛋白質及びその利用 |
| GB0426393D0 (en) | 2004-12-01 | 2005-01-05 | Cancer Rec Tech Ltd | Materials and methods relating to modulators of spindle checkpoint kinases |
| RU2403574C2 (ru) | 2004-12-08 | 2010-11-10 | Авентис Фармасьютикалз Инк. | Способ измерения резистентности или чувствительности к доцетакселу |
| JP5109131B2 (ja) | 2005-02-10 | 2012-12-26 | オンコセラピー・サイエンス株式会社 | 膀胱癌を診断する方法 |
| DK2325306T3 (en) | 2005-02-25 | 2014-03-03 | Oncotherapy Science Inc | Peptide vaccines against lung cancers expressing TTK, URLC10 or KOC1 polypeptide |
| EP2305811A1 (en) | 2005-07-27 | 2011-04-06 | Oncotherapy Science, Inc. | Method of diagnosing smal cell lung cancer |
| EP2311986B1 (en) | 2005-07-27 | 2015-04-15 | Oncotherapy Science, Inc. | Method of diagnosing esophageal cancer |
| JP2010512730A (ja) | 2006-12-13 | 2010-04-30 | オンコセラピー・サイエンス株式会社 | 肺癌の腫瘍マーカーおよび治療標的としてのｔｔｋ |
| CA2708686A1 (en) | 2007-12-21 | 2009-07-02 | University Health Network | Methods of inhibiting tumor growth using ttk antagonists |
| TW201008574A (en) | 2008-08-19 | 2010-03-01 | Oncotherapy Science Inc | INHBB epitope peptides and vaccines containing the same |
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Patent Citations (1)
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|---|---|---|---|---|
| RU2464275C2 (ru) * | 2007-02-21 | 2012-10-20 | Онкотерапи Сайенс, Инк. | Пептидные вакцины для раков, экспрессирующих опухолеспецифические антигены |
Non-Patent Citations (1)
| Title |
|---|
| SUDA T. ET AL.: 'Identification of human leukocyte antigen-A24-restricted epitope peptides derived from gene products upregulated in lung and esophageal cancers as novel targets for immunotherapy' CANCER SCIENCE,2007, vol. 98, no. 11, pages 1803 - 1808 . MILLS G B ET AL: "EXPRESSION OF TTK A NOVEL HUMAN PROTEIN KINASE IS ASSOCIATED WITH CELL PROLIFERATION", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1992, vol. 267, no. 22, pages 16000-16006 * |
Also Published As
| Publication number | Publication date |
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| JP5786178B2 (ja) | 2015-09-30 |
| CA2761393A1 (en) | 2010-11-18 |
| EP2430039A1 (en) | 2012-03-21 |
| WO2010131452A1 (en) | 2010-11-18 |
| EP2430039A4 (en) | 2012-12-05 |
| TW201102081A (en) | 2011-01-16 |
| AU2010248702A1 (en) | 2011-11-17 |
| US20120135020A1 (en) | 2012-05-31 |
| RU2011150283A (ru) | 2013-06-20 |
| SG175998A1 (en) | 2011-12-29 |
| CN102459314A (zh) | 2012-05-16 |
| US8530430B2 (en) | 2013-09-10 |
| BRPI1013938A2 (pt) | 2019-09-24 |
| CN102459314B (zh) | 2016-01-20 |
| MX2011012013A (es) | 2012-02-23 |
| KR20120029394A (ko) | 2012-03-26 |
| JP2012526519A (ja) | 2012-11-01 |
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