RU2527156C2 - Автоматический инструмент для введения жидких фармацевтических препаратов, в частности инсулина - Google Patents
Автоматический инструмент для введения жидких фармацевтических препаратов, в частности инсулина Download PDFInfo
- Publication number
- RU2527156C2 RU2527156C2 RU2012117569/14A RU2012117569A RU2527156C2 RU 2527156 C2 RU2527156 C2 RU 2527156C2 RU 2012117569/14 A RU2012117569/14 A RU 2012117569/14A RU 2012117569 A RU2012117569 A RU 2012117569A RU 2527156 C2 RU2527156 C2 RU 2527156C2
- Authority
- RU
- Russia
- Prior art keywords
- piston
- spring
- dose
- drive unit
- drug
- Prior art date
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- 239000007788 liquid Substances 0.000 title claims abstract description 7
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title claims description 46
- 102000004877 Insulin Human genes 0.000 title claims description 23
- 108090001061 Insulin Proteins 0.000 title claims description 23
- 229940125396 insulin Drugs 0.000 title claims description 23
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract description 3
- 239000003814 drug Substances 0.000 claims abstract description 25
- 229940079593 drug Drugs 0.000 claims abstract description 20
- 230000000903 blocking effect Effects 0.000 claims description 7
- 230000008878 coupling Effects 0.000 abstract description 6
- 238000010168 coupling process Methods 0.000 abstract description 6
- 238000005859 coupling reaction Methods 0.000 abstract description 6
- 238000001647 drug administration Methods 0.000 abstract description 2
- 239000000126 substance Substances 0.000 abstract 1
- 238000003780 insertion Methods 0.000 description 14
- 230000037431 insertion Effects 0.000 description 14
- 230000007246 mechanism Effects 0.000 description 8
- 238000002347 injection Methods 0.000 description 6
- 239000007924 injection Substances 0.000 description 6
- 241000282472 Canis lupus familiaris Species 0.000 description 5
- 229940126601 medicinal product Drugs 0.000 description 4
- 230000001681 protective effect Effects 0.000 description 3
- 230000002411 adverse Effects 0.000 description 1
- 239000003708 ampul Substances 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31543—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
-
- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31553—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe without axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2006—Having specific accessories
- A61M2005/202—Having specific accessories cocking means, e.g. to bias the main drive spring of an injector
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
- A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2485—Ampoule holder connected to rest of syringe
- A61M2005/2488—Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3114—Filling or refilling
- A61M2005/3115—Filling or refilling spring-assisted
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL389427A PL215310B1 (pl) | 2009-10-30 | 2009-10-30 | Automatyczny aplikator, zwlaszcza do insuliny |
| PLP.389427 | 2009-10-30 | ||
| PCT/EP2010/054128 WO2010089418A2 (en) | 2009-10-30 | 2010-03-29 | Automatic applicator for liquid pharmaceutical preparations, particularly for insulin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2012117569A RU2012117569A (ru) | 2013-12-10 |
| RU2527156C2 true RU2527156C2 (ru) | 2014-08-27 |
Family
ID=42542446
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2012117569/14A RU2527156C2 (ru) | 2009-10-30 | 2010-03-29 | Автоматический инструмент для введения жидких фармацевтических препаратов, в частности инсулина |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US9566386B2 (enExample) |
| EP (3) | EP3235531A1 (enExample) |
| JP (3) | JP5802211B2 (enExample) |
| KR (2) | KR101988582B1 (enExample) |
| CN (1) | CN102573962B (enExample) |
| AU (1) | AU2010210090B2 (enExample) |
| BR (1) | BR112012005853B8 (enExample) |
| CA (1) | CA2773242C (enExample) |
| DK (2) | DK2913075T3 (enExample) |
| ES (2) | ES2536838T3 (enExample) |
| PL (1) | PL215310B1 (enExample) |
| RU (1) | RU2527156C2 (enExample) |
| WO (1) | WO2010089418A2 (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6663602B2 (en) | 2000-06-16 | 2003-12-16 | Novo Nordisk A/S | Injection device |
| RU2389514C2 (ru) | 2004-10-21 | 2010-05-20 | Ново Нордиск А/С | Механизм установки дозы для шприца-ручки |
| BRPI0712028A2 (pt) | 2006-05-18 | 2011-12-20 | Novo Nordisk As | dispositivo de injenção com um meio de travamento de modo |
| US7959598B2 (en) | 2008-08-20 | 2011-06-14 | Asante Solutions, Inc. | Infusion pump systems and methods |
| GB0918145D0 (en) | 2009-10-16 | 2009-12-02 | Owen Mumford Ltd | Injector apparatus |
| PL215310B1 (pl) * | 2009-10-30 | 2013-11-29 | Kappa Medilab Spolka Z Ograniczona Odpowiedzialnoscia | Automatyczny aplikator, zwlaszcza do insuliny |
| GB201018827D0 (en) | 2010-11-08 | 2010-12-22 | Owen Mumford Ltd | Injection device |
| EP2468329A1 (en) * | 2010-12-21 | 2012-06-27 | Sanofi-Aventis Deutschland GmbH | Auto injector with a torsion spring |
| CN103517729B (zh) * | 2011-05-12 | 2016-06-08 | Shl集团有限责任公司 | 药剂输送装置 |
| CN103998077B (zh) | 2011-12-29 | 2017-05-31 | 诺沃—诺迪斯克有限公司 | 具有向上拨动/向下拨动定量机构的基于扭力弹簧的卷紧自动注射器笔 |
| PL220720B1 (pl) * | 2012-02-08 | 2015-12-31 | Copernicus Spółka Z Ograniczoną Odpowiedzialnością | Urządzenie wstrzykujące z mechanizmem resetu dawki |
| ES2988610T3 (es) | 2012-03-30 | 2024-11-21 | Insulet Corp | Dispositivo de administración de fluido con herramienta de acceso transcutáneo, mecanismo de inserción y monitorización de glucemia para su uso con el mismo |
| GB2501897B (en) | 2012-05-09 | 2014-09-03 | Owen Mumford Ltd | Injection devices |
| US9675760B2 (en) * | 2012-05-30 | 2017-06-13 | Sanofi-Aventis Deutschland Gmbh | Drive mechanism for a drug delivery device and drug delivery device |
| CA2874564A1 (en) | 2012-05-31 | 2013-12-05 | Simon Munch Pedersen | Dial-down mechanism for wind-up pen |
| WO2014180744A1 (en) | 2013-05-07 | 2014-11-13 | Sanofi-Aventis Deutschland Gmbh | A supplemental device for attachment to an injection device |
| DK3003439T3 (da) * | 2013-05-27 | 2021-09-13 | Sanofi Aventis Deutschland | Enhed til en anordning til indgivelse af lægemidler samt anordning til indgivelse af lægemidler |
| US20160144128A1 (en) * | 2013-07-17 | 2016-05-26 | Sanofi | Counting mechanism for a drug delivery device |
| US9561324B2 (en) | 2013-07-19 | 2017-02-07 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
| US10569015B2 (en) | 2013-12-02 | 2020-02-25 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
| EP3094361B1 (en) * | 2014-01-13 | 2018-03-14 | Novo Nordisk A/S | Transmission arrangement for motorized drug delivery device |
| US20170296748A1 (en) | 2014-10-08 | 2017-10-19 | Novo Nordisk A/S | Torsion Spring for an Injection Device and an Injection Device Comprising Such Torsion Spring |
| DK3223884T3 (da) * | 2014-11-24 | 2023-07-31 | Sanofi Sa | Lægemiddeladministrationsanordning med variabel stempelkraft |
| JP6637062B2 (ja) | 2015-02-27 | 2020-01-29 | ノボ・ノルデイスク・エー/エス | 用量リセット機構を有する薬剤送達装置 |
| EP3064239A1 (en) * | 2015-03-05 | 2016-09-07 | Carebay Europe Ltd. | Medicament delivery device with information provider system |
| JP6932644B2 (ja) | 2015-04-29 | 2021-09-08 | ノボ・ノルデイスク・エー/エス | ばね機構を有する薬剤送達装置 |
| US9878097B2 (en) | 2015-04-29 | 2018-01-30 | Bigfoot Biomedical, Inc. | Operating an infusion pump system |
| CN106259891A (zh) * | 2015-05-28 | 2017-01-04 | 上海旺旺食品集团有限公司 | 一种益生菌口含片及其制备方法 |
| PL414382A1 (pl) | 2015-10-15 | 2017-04-24 | Copernicus Spółka Z Ograniczoną Odpowiedzialnością | Mechanizm nastawczy, w szczególności do dozowania |
| PL227678B1 (pl) | 2015-12-22 | 2018-01-31 | Copernicus Spolka Z Ograniczona Odpowiedzialnoscia | Układ sterująco-napędowy dla urządzenia do iniekcji oraz urządzenie do iniekcji zaopatrzone w taki układ |
| CN114053517A (zh) | 2016-01-05 | 2022-02-18 | 比格福特生物医药公司 | 操作多模式药物输送系统 |
| US10449294B1 (en) | 2016-01-05 | 2019-10-22 | Bigfoot Biomedical, Inc. | Operating an infusion pump system |
| WO2017123703A2 (en) | 2016-01-14 | 2017-07-20 | Bigfoot Biomedical, Inc. | Occlusion resolution in medication delivery devices, systems, and methods |
| CN106039475B (zh) * | 2016-05-18 | 2019-08-02 | 苏州鹏烨医疗科技有限公司 | 一种注射笔 |
| EP3108914B1 (en) | 2016-07-07 | 2019-02-27 | Copernicus SP. Z O.O. | Injection device for delivering a defined number of equal doses of a liquid substance |
| WO2018041899A1 (en) | 2016-08-31 | 2018-03-08 | Novo Nordisk A/S | Drug delivery device with over-torque protection mechanism |
| US10302598B2 (en) | 2016-10-24 | 2019-05-28 | General Electric Company | Corrosion and crack detection for fastener nuts |
| PL232651B1 (pl) | 2017-07-18 | 2019-07-31 | Copernicus Spolka Z Ograniczona Odpowiedzialnoscia | Sprzęgło z systemem blokowania dla medycznego urządzenia wstrzykującego |
| CN107308523A (zh) * | 2017-08-08 | 2017-11-03 | 甘肃成纪生物药业有限公司 | 微调注射笔 |
| PL237295B1 (pl) * | 2018-11-28 | 2021-04-06 | Copernicus Spolka Z Ograniczona Odpowiedzialnoscia | Mechanizm sterujący aplikatora i sposób jego montażu |
| RU2729432C1 (ru) * | 2019-10-23 | 2020-08-06 | Общество с ограниченной ответственностью «НЭКСТ БИО» | Устройство для доставки лекарственного средства |
| CN111558102B (zh) * | 2020-05-25 | 2020-12-15 | 宋娜 | 一种带自动上药装置的胰岛素注射盒 |
| CN115252094A (zh) * | 2021-04-30 | 2022-11-01 | 张任贤 | 一种注射器推进器 |
| CN113730729B (zh) * | 2021-09-13 | 2023-08-18 | 郑州瑞宇科技有限公司 | 一种手电动一体胰岛素注射笔及其注射方法 |
| KR102726943B1 (ko) * | 2022-01-04 | 2024-11-07 | 이오플로우(주) | 약액 주입 장치 |
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- 2010-03-29 KR KR1020187014935A patent/KR101988582B1/ko not_active Expired - Fee Related
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- 2010-03-29 KR KR1020127011308A patent/KR101863938B1/ko active Active
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- 2010-03-29 JP JP2012535690A patent/JP5802211B2/ja not_active Expired - Fee Related
- 2010-03-29 BR BR112012005853A patent/BR112012005853B8/pt active IP Right Grant
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- 2010-03-29 WO PCT/EP2010/054128 patent/WO2010089418A2/en not_active Ceased
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- 2010-03-29 CN CN201080046137.0A patent/CN102573962B/zh active Active
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2012
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2015
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2016
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