RU2504373C2 - Способы и композиции для перорального введения протеинов - Google Patents

Способы и композиции для перорального введения протеинов Download PDF

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Publication number
RU2504373C2
RU2504373C2 RU2010141292/10A RU2010141292A RU2504373C2 RU 2504373 C2 RU2504373 C2 RU 2504373C2 RU 2010141292/10 A RU2010141292/10 A RU 2010141292/10A RU 2010141292 A RU2010141292 A RU 2010141292A RU 2504373 C2 RU2504373 C2 RU 2504373C2
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Russia
Prior art keywords
another embodiment
protein
present
insulin
oral administration
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RU2010141292/10A
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English (en)
Russian (ru)
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RU2010141292A (ru
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Мириам КИДРОН
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ОРАМЕД Лтд.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2278Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/60Fish, e.g. seahorses; Fish eggs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/56Protease inhibitors from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/57Protease inhibitors from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Botany (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RU2010141292/10A 2008-03-26 2009-02-26 Способы и композиции для перорального введения протеинов RU2504373C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6477908P 2008-03-26 2008-03-26
US61/064,779 2008-03-26
PCT/IL2009/000223 WO2009118722A2 (en) 2008-03-26 2009-02-26 Methods and compositions for oral administration of proteins

Publications (2)

Publication Number Publication Date
RU2010141292A RU2010141292A (ru) 2012-05-10
RU2504373C2 true RU2504373C2 (ru) 2014-01-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU2010141292/10A RU2504373C2 (ru) 2008-03-26 2009-02-26 Способы и композиции для перорального введения протеинов

Country Status (10)

Country Link
US (3) US10058593B2 (enExample)
EP (2) EP2279244B1 (enExample)
JP (1) JP5395160B2 (enExample)
CN (1) CN102037121B (enExample)
AU (1) AU2009230718B2 (enExample)
CA (3) CA3083198A1 (enExample)
NZ (1) NZ588603A (enExample)
RU (1) RU2504373C2 (enExample)
WO (1) WO2009118722A2 (enExample)
ZA (1) ZA201007522B (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2826190C2 (ru) * 2018-06-11 2024-09-05 ОРАМЕД Лтд. Композиции, содержащие рекомбинантный ингибитор протеазы, способы их получения и их применение

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EP2300031B1 (en) * 2008-05-05 2017-09-20 Oramed Ltd. Methods and compositions for oral administration of exenatide
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ES2644962T3 (es) * 2012-01-03 2017-12-01 Oramed Ltd. Cápsulas que contiene composiciones líquidas basadas en aceite de agentes terapéuticos combinados para tratar la diabetes
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US20160009767A9 (en) * 2012-03-28 2016-01-14 Affibody Ab Oral administration
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2826190C2 (ru) * 2018-06-11 2024-09-05 ОРАМЕД Лтд. Композиции, содержащие рекомбинантный ингибитор протеазы, способы их получения и их применение

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CA2719272C (en) 2020-08-18
AU2009230718A1 (en) 2009-10-01
RU2010141292A (ru) 2012-05-10
CA2719272A1 (en) 2009-10-01
AU2009230718B2 (en) 2013-07-11
CA3083198A1 (en) 2009-10-01
US11660327B2 (en) 2023-05-30
EP3777831A1 (en) 2021-02-17
JP2011515458A (ja) 2011-05-19
JP5395160B2 (ja) 2014-01-22
US10881714B2 (en) 2021-01-05
US20110014247A1 (en) 2011-01-20
NZ588603A (en) 2012-03-30
BRPI0907077A2 (pt) 2016-07-26
CN102037121B (zh) 2013-07-10
EP2279244B1 (en) 2020-07-01
WO2009118722A2 (en) 2009-10-01
US20210113663A1 (en) 2021-04-22
WO2009118722A3 (en) 2010-03-11
US10058593B2 (en) 2018-08-28
EP3777831B1 (en) 2023-11-29
EP2279244A2 (en) 2011-02-02
CA3083698A1 (en) 2009-10-01
CN102037121A (zh) 2011-04-27
EP2279244A4 (en) 2013-11-20
ZA201007522B (en) 2012-12-27
US20180369339A1 (en) 2018-12-27

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