AU2009230718B2 - Methods and compositions for oral administration of proteins - Google Patents

Methods and compositions for oral administration of proteins Download PDF

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Publication number
AU2009230718B2
AU2009230718B2 AU2009230718A AU2009230718A AU2009230718B2 AU 2009230718 B2 AU2009230718 B2 AU 2009230718B2 AU 2009230718 A AU2009230718 A AU 2009230718A AU 2009230718 A AU2009230718 A AU 2009230718A AU 2009230718 B2 AU2009230718 B2 AU 2009230718B2
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AU
Australia
Prior art keywords
another embodiment
amount
present
insulin
protein
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AU2009230718A
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English (en)
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AU2009230718A1 (en
Inventor
Miriam Kidron
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Oramed Ltd
Original Assignee
Oramed Ltd
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Filing date
Publication date
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Publication of AU2009230718A1 publication Critical patent/AU2009230718A1/en
Application granted granted Critical
Publication of AU2009230718B2 publication Critical patent/AU2009230718B2/en
Priority to AU2013237663A priority Critical patent/AU2013237663B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/60—Fish, e.g. seahorses; Fish eggs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/56—Protease inhibitors from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Botany (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2009230718A 2008-03-26 2009-02-26 Methods and compositions for oral administration of proteins Active AU2009230718B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2013237663A AU2013237663B2 (en) 2008-03-26 2013-10-02 Methods and compositions for oral administration of proteins

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6477908P 2008-03-26 2008-03-26
US61/064,779 2008-03-26
PCT/IL2009/000223 WO2009118722A2 (en) 2008-03-26 2009-02-26 Methods and compositions for oral administration of proteins

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2013237663A Division AU2013237663B2 (en) 2008-03-26 2013-10-02 Methods and compositions for oral administration of proteins

Publications (2)

Publication Number Publication Date
AU2009230718A1 AU2009230718A1 (en) 2009-10-01
AU2009230718B2 true AU2009230718B2 (en) 2013-07-11

Family

ID=41114402

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009230718A Active AU2009230718B2 (en) 2008-03-26 2009-02-26 Methods and compositions for oral administration of proteins

Country Status (10)

Country Link
US (3) US10058593B2 (enExample)
EP (2) EP2279244B1 (enExample)
JP (1) JP5395160B2 (enExample)
CN (1) CN102037121B (enExample)
AU (1) AU2009230718B2 (enExample)
CA (3) CA3083198A1 (enExample)
NZ (1) NZ588603A (enExample)
RU (1) RU2504373C2 (enExample)
WO (1) WO2009118722A2 (enExample)
ZA (1) ZA201007522B (enExample)

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AU2006288703B2 (en) * 2005-09-06 2011-09-22 Oramed Pharmaceuticals, Inc. Methods and compositions for oral administration of proteins
CA3083198A1 (en) 2008-03-26 2009-10-01 Oramed Ltd. Methods and compositions for oral administration of proteins
EP2300031B1 (en) * 2008-05-05 2017-09-20 Oramed Ltd. Methods and compositions for oral administration of exenatide
ES2561652T3 (es) 2010-02-25 2016-02-29 Evonik Röhm Gmbh Formulación farmacéutica o nutracéutica
NZ604805A (en) 2010-07-09 2014-09-26 Affibody Ab Polypeptides
ES2644962T3 (es) * 2012-01-03 2017-12-01 Oramed Ltd. Cápsulas que contiene composiciones líquidas basadas en aceite de agentes terapéuticos combinados para tratar la diabetes
EP4082530B1 (en) * 2012-02-01 2024-04-10 Oramed Ltd. Protease inhibitor-containing compositions, compositions comprising same, and methods for producing and using same
US20160009767A9 (en) * 2012-03-28 2016-01-14 Affibody Ab Oral administration
US10155792B2 (en) 2012-09-25 2018-12-18 Affibody Ab Albumin binding polypeptide
EP2941267B1 (en) * 2013-01-03 2022-11-16 Oramed Ltd. Compositions for use in treating nafld
WO2014191545A1 (en) * 2013-05-30 2014-12-04 Novo Nordisk A/S Novel oral pharmaceutical composition for treatment of diabetes
EP3083675B1 (en) 2013-12-20 2018-03-07 Affibody AB Engineered albumin binding polypeptide
CN104922682A (zh) * 2014-03-20 2015-09-23 中国科学院大连化学物理研究所 一种胰蛋白酶抑制剂及其应用
US10689460B2 (en) 2014-05-15 2020-06-23 Incube Labs, Llc PCSK9 antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
CA2949236C (en) 2014-05-15 2023-06-13 Incube Labs, Llc Pharmaceutical compositions and methods for fabrication of solid masses comprising polypeptides and/or proteins
US10265384B2 (en) 2015-01-29 2019-04-23 Novo Nordisk A/S Tablets comprising GLP-1 agonist and enteric coating
CN113230386B (zh) * 2021-03-07 2022-04-12 合肥天汇孵化科技有限公司 胸腺法新组合物及其用途
US20240366731A1 (en) * 2021-08-12 2024-11-07 Celagenex Research (India) Pvt. Ltd. Oral algal oil based gastro-intestinal tract permeable peptide composition
KR20230039783A (ko) * 2021-09-07 2023-03-21 ㈜ 디앤디파마텍 거대 생리활성 물질 및 부형제를 포함하는 약학 조성물
WO2025147459A1 (en) * 2024-01-04 2025-07-10 Nano Precision Medical, Inc. Stabilization of peptides and proteins in implantable devices and formulations
WO2025240494A1 (en) 2024-05-13 2025-11-20 Lumen Bioscience, Inc. Leptin compositions and methods of making and using the same to support weight loss and/or maintenance

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Also Published As

Publication number Publication date
CA2719272C (en) 2020-08-18
AU2009230718A1 (en) 2009-10-01
RU2010141292A (ru) 2012-05-10
CA2719272A1 (en) 2009-10-01
CA3083198A1 (en) 2009-10-01
US11660327B2 (en) 2023-05-30
EP3777831A1 (en) 2021-02-17
RU2504373C2 (ru) 2014-01-20
JP2011515458A (ja) 2011-05-19
JP5395160B2 (ja) 2014-01-22
US10881714B2 (en) 2021-01-05
US20110014247A1 (en) 2011-01-20
NZ588603A (en) 2012-03-30
BRPI0907077A2 (pt) 2016-07-26
CN102037121B (zh) 2013-07-10
EP2279244B1 (en) 2020-07-01
WO2009118722A2 (en) 2009-10-01
US20210113663A1 (en) 2021-04-22
WO2009118722A3 (en) 2010-03-11
US10058593B2 (en) 2018-08-28
EP3777831B1 (en) 2023-11-29
EP2279244A2 (en) 2011-02-02
CA3083698A1 (en) 2009-10-01
CN102037121A (zh) 2011-04-27
EP2279244A4 (en) 2013-11-20
ZA201007522B (en) 2012-12-27
US20180369339A1 (en) 2018-12-27

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