RU2500389C2 - Слой для защиты твердых дозированных форм от механического воздействия - Google Patents

Слой для защиты твердых дозированных форм от механического воздействия Download PDF

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Publication number
RU2500389C2
RU2500389C2 RU2010117391/15A RU2010117391A RU2500389C2 RU 2500389 C2 RU2500389 C2 RU 2500389C2 RU 2010117391/15 A RU2010117391/15 A RU 2010117391/15A RU 2010117391 A RU2010117391 A RU 2010117391A RU 2500389 C2 RU2500389 C2 RU 2500389C2
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RU
Russia
Prior art keywords
layer
mechanical stress
protection against
against mechanical
polyethylene glycol
Prior art date
Application number
RU2010117391/15A
Other languages
English (en)
Russian (ru)
Other versions
RU2010117391A (ru
Inventor
РАНСАНИ Луис СОЛЕР
ПУХАЛС Хемма КАСАДЕВАЛЬ
Original Assignee
Лабораторьос Дель Др. Эстеве, С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Лабораторьос Дель Др. Эстеве, С.А. filed Critical Лабораторьос Дель Др. Эстеве, С.А.
Publication of RU2010117391A publication Critical patent/RU2010117391A/ru
Application granted granted Critical
Publication of RU2500389C2 publication Critical patent/RU2500389C2/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Optical Filters (AREA)
  • Paints Or Removers (AREA)
RU2010117391/15A 2007-10-04 2008-10-03 Слой для защиты твердых дозированных форм от механического воздействия RU2500389C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07380270A EP2044932A1 (en) 2007-10-04 2007-10-04 Mechanical protective layer for solid dosage forms
EP07380270.4 2007-10-04
PCT/EP2008/063279 WO2009043929A1 (en) 2007-10-04 2008-10-03 Mechanical protective layer for solid dosage forms

Publications (2)

Publication Number Publication Date
RU2010117391A RU2010117391A (ru) 2011-11-10
RU2500389C2 true RU2500389C2 (ru) 2013-12-10

Family

ID=39154060

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2010117391/15A RU2500389C2 (ru) 2007-10-04 2008-10-03 Слой для защиты твердых дозированных форм от механического воздействия

Country Status (16)

Country Link
US (1) US20100247641A1 (es)
EP (2) EP2044932A1 (es)
JP (1) JP5442620B2 (es)
KR (1) KR20100091956A (es)
CN (1) CN101820866B (es)
AU (1) AU2008306846B2 (es)
BR (1) BRPI0817863A2 (es)
CA (1) CA2701556A1 (es)
ES (1) ES2507079T3 (es)
HK (1) HK1144180A1 (es)
IL (1) IL204815A0 (es)
MX (1) MX2010003591A (es)
NZ (1) NZ584453A (es)
RU (1) RU2500389C2 (es)
WO (1) WO2009043929A1 (es)
ZA (1) ZA201002257B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2949062B1 (fr) * 2009-08-12 2011-09-02 Debregeas Et Associes Pharma Nouvelles formulations pharmaceutiques contre le mesusage des medicaments
EP2468263A1 (en) * 2010-12-23 2012-06-27 Laboratorios Del. Dr. Esteve, S.A. Compressed solid dosage forms
EP3288556A4 (en) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
JP7064683B2 (ja) * 2017-01-27 2022-05-11 日本ケミファ株式会社 腸溶層破損防止用組成物
CN116270514A (zh) * 2023-03-22 2023-06-23 北京恒创星远医药科技有限公司 一种微丸片剂及其制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2166935C2 (ru) * 1994-07-08 2001-05-20 Астра Актиеболаг Таблетированная многоединичная лекарственная форма, способ ее получения, способ ингибирования секреции желудочной кислоты или лечения желудочно-кишечных заболеваний у млекопитающих и человека

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57171428A (en) * 1981-04-13 1982-10-22 Sankyo Co Ltd Preparation of coated solid preparation
US4684516A (en) * 1983-08-01 1987-08-04 Alra Laboratories, Inc. Sustained release tablets and method of making same
JPH07106989B2 (ja) * 1988-09-27 1995-11-15 武田薬品工業株式会社 腸溶性被膜
US5464632C1 (en) * 1991-07-22 2001-02-20 Prographarm Lab Rapidly disintegratable multiparticular tablet
US5447729A (en) * 1994-04-07 1995-09-05 Pharmavene, Inc. Multilamellar drug delivery systems
US6699885B2 (en) * 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
SE512835C2 (sv) * 1996-01-08 2000-05-22 Astrazeneca Ab Doseringsform innehållande en mångfald enheter alla inneslutande syralabil H+K+ATPas-hämmare
ES2274625T3 (es) * 1998-05-18 2007-05-16 Takeda Pharmaceutical Company Limited Comprimidos desintegrables en la boca que comprenden un bencimidazol.
US6322819B1 (en) * 1998-10-21 2001-11-27 Shire Laboratories, Inc. Oral pulsed dose drug delivery system
US6835750B1 (en) * 2000-05-01 2004-12-28 Accera, Inc. Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II
US6565873B1 (en) * 2000-10-25 2003-05-20 Salvona Llc Biodegradable bioadhesive controlled release system of nano-particles for oral care products
US6673373B2 (en) * 2001-02-01 2004-01-06 Carlsbad Technology Inc. Antifungal formulation and the methods for manufacturing and using the same
JP5138856B2 (ja) * 2001-06-20 2013-02-06 武田薬品工業株式会社 錠剤の製造方法
US6766817B2 (en) * 2001-07-25 2004-07-27 Tubarc Technologies, Llc Fluid conduction utilizing a reversible unsaturated siphon with tubarc porosity action
FR2837100B1 (fr) * 2002-03-18 2004-07-23 Flamel Tech Sa Comprimes a bases de microcapsules a liberation modifiee
CN1674877A (zh) * 2002-06-07 2005-09-28 兰贝克赛实验室有限公司 控释的多单位药物释放系统
US7285255B2 (en) * 2002-12-10 2007-10-23 Ecolab Inc. Deodorizing and sanitizing employing a wicking device
GB0302673D0 (en) * 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
ES2261006B1 (es) 2004-06-10 2007-11-01 Laboratorios Rubio, S.A. Pellet multicapa de liberacion controlada de metilfenidato.
US20060051462A1 (en) * 2004-09-03 2006-03-09 Wang Jimmy X Self emulsifying compositions for delivering lipophilic coenzyme Q10 and other dietary ingredients
BRPI0614545B8 (pt) * 2005-08-15 2021-05-25 Abbott Products Gmbh composição farmacêutica de liberação controlada, seu processo de produção, forma de dosagem oral com revestimento entérico de pacreatina e uso da mesma
EP2044929A1 (en) * 2007-10-04 2009-04-08 Laboratorios del Dr. Esteve S.A. Oral fast distintegrating tablets

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2166935C2 (ru) * 1994-07-08 2001-05-20 Астра Актиеболаг Таблетированная многоединичная лекарственная форма, способ ее получения, способ ингибирования секреции желудочной кислоты или лечения желудочно-кишечных заболеваний у млекопитающих и человека

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
V.S.N. MURTHY DWIBHASHYAM «Key formulation variables in tableting of coated pellets», Indian J Pharm Sci., 2008. КНУНЯНЦ И.Л. Химическая энциклопедия в 5 т., т.1, 1988, с.425. *
ЧУЕШОВ В.И. Промышленная технология лекарств, 2002, т.2. с.332, табл.14.4. КОРЖАВЫХ Э.А. Таблетки и их разновидности. - Российские аптеки, 2003, №12. HEINAMAKI J.M. «The mechanical and moisture permeability properties of aqueous-based hydroxypropyl methylcellulose coating systems plasticized with polyethylene glycol». International journal of pharmaceutics, 1994, vol.112, №2. *

Also Published As

Publication number Publication date
ZA201002257B (en) 2011-06-29
AU2008306846B2 (en) 2013-09-05
BRPI0817863A2 (pt) 2015-03-31
AU2008306846A1 (en) 2009-04-09
JP2010540596A (ja) 2010-12-24
KR20100091956A (ko) 2010-08-19
CA2701556A1 (en) 2009-04-09
HK1144180A1 (en) 2011-02-02
EP2207534B1 (en) 2014-07-09
WO2009043929A1 (en) 2009-04-09
EP2044932A1 (en) 2009-04-08
NZ584453A (en) 2012-06-29
JP5442620B2 (ja) 2014-03-12
CN101820866A (zh) 2010-09-01
CN101820866B (zh) 2012-12-05
MX2010003591A (es) 2010-04-21
US20100247641A1 (en) 2010-09-30
RU2010117391A (ru) 2011-11-10
ES2507079T3 (es) 2014-10-14
EP2207534A1 (en) 2010-07-21
IL204815A0 (en) 2010-11-30

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Effective date: 20211207