ES2507079T3 - Capa protectora mecánica para formas de dosificación sólidas - Google Patents

Capa protectora mecánica para formas de dosificación sólidas Download PDF

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Publication number
ES2507079T3
ES2507079T3 ES08835025.1T ES08835025T ES2507079T3 ES 2507079 T3 ES2507079 T3 ES 2507079T3 ES 08835025 T ES08835025 T ES 08835025T ES 2507079 T3 ES2507079 T3 ES 2507079T3
Authority
ES
Spain
Prior art keywords
protective layer
mechanical protective
dosage forms
solid dosage
polyethylene glycol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES08835025.1T
Other languages
English (en)
Inventor
Luis Soler Ranzani
Gemma Casadevall Pujals
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esteve Pharmaceuticals SA
Original Assignee
Laboratorios del Dr Esteve SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios del Dr Esteve SA filed Critical Laboratorios del Dr Esteve SA
Application granted granted Critical
Publication of ES2507079T3 publication Critical patent/ES2507079T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Paints Or Removers (AREA)
  • Optical Filters (AREA)

Abstract

Una capa protectora mecánica para una forma de dosificación que comprende dos o más agentes plastificantes, en la que un primer agente plastificante es un primer polietilenglicol con un peso molecular promedio menor de 6000 y un segundo agente plastificante es un segundo polietilenglicol diferente del primer polietilenglicol y en la que dicha capa protectora mecánica está presente sobre un gránulo o pella con recubrimiento entérico y en la que ella comprende al menos el 80 % p/p de agentes plastificantes.

Description

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Claims (1)

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    imagen2
ES08835025.1T 2007-10-04 2008-10-03 Capa protectora mecánica para formas de dosificación sólidas Active ES2507079T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07380270A EP2044932A1 (en) 2007-10-04 2007-10-04 Mechanical protective layer for solid dosage forms
EP07380270 2007-10-04
PCT/EP2008/063279 WO2009043929A1 (en) 2007-10-04 2008-10-03 Mechanical protective layer for solid dosage forms

Publications (1)

Publication Number Publication Date
ES2507079T3 true ES2507079T3 (es) 2014-10-14

Family

ID=39154060

Family Applications (1)

Application Number Title Priority Date Filing Date
ES08835025.1T Active ES2507079T3 (es) 2007-10-04 2008-10-03 Capa protectora mecánica para formas de dosificación sólidas

Country Status (16)

Country Link
US (1) US20100247641A1 (es)
EP (2) EP2044932A1 (es)
JP (1) JP5442620B2 (es)
KR (1) KR20100091956A (es)
CN (1) CN101820866B (es)
AU (1) AU2008306846B2 (es)
BR (1) BRPI0817863A2 (es)
CA (1) CA2701556A1 (es)
ES (1) ES2507079T3 (es)
HK (1) HK1144180A1 (es)
IL (1) IL204815A0 (es)
MX (1) MX2010003591A (es)
NZ (1) NZ584453A (es)
RU (1) RU2500389C2 (es)
WO (1) WO2009043929A1 (es)
ZA (1) ZA201002257B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2949062B1 (fr) * 2009-08-12 2011-09-02 Debregeas Et Associes Pharma Nouvelles formulations pharmaceutiques contre le mesusage des medicaments
EP2468263A1 (en) * 2010-12-23 2012-06-27 Laboratorios Del. Dr. Esteve, S.A. Compressed solid dosage forms
EP3288556A4 (en) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
JP7064683B2 (ja) * 2017-01-27 2022-05-11 日本ケミファ株式会社 腸溶層破損防止用組成物
CN116270514A (zh) * 2023-03-22 2023-06-23 北京恒创星远医药科技有限公司 一种微丸片剂及其制备方法

Family Cites Families (23)

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Publication number Priority date Publication date Assignee Title
JPS57171428A (en) * 1981-04-13 1982-10-22 Sankyo Co Ltd Preparation of coated solid preparation
US4684516A (en) * 1983-08-01 1987-08-04 Alra Laboratories, Inc. Sustained release tablets and method of making same
JPH07106989B2 (ja) * 1988-09-27 1995-11-15 武田薬品工業株式会社 腸溶性被膜
US5464632C1 (en) * 1991-07-22 2001-02-20 Prographarm Lab Rapidly disintegratable multiparticular tablet
US5447729A (en) * 1994-04-07 1995-09-05 Pharmavene, Inc. Multilamellar drug delivery systems
SE9402431D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New tablet formulation
US6699885B2 (en) * 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
SE512835C2 (sv) * 1996-01-08 2000-05-22 Astrazeneca Ab Doseringsform innehållande en mångfald enheter alla inneslutande syralabil H+K+ATPas-hämmare
ES2274625T3 (es) * 1998-05-18 2007-05-16 Takeda Pharmaceutical Company Limited Comprimidos desintegrables en la boca que comprenden un bencimidazol.
US20010055613A1 (en) * 1998-10-21 2001-12-27 Beth A. Burnside Oral pulsed dose drug delivery system
US6835750B1 (en) * 2000-05-01 2004-12-28 Accera, Inc. Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II
US6565873B1 (en) * 2000-10-25 2003-05-20 Salvona Llc Biodegradable bioadhesive controlled release system of nano-particles for oral care products
US6673373B2 (en) * 2001-02-01 2004-01-06 Carlsbad Technology Inc. Antifungal formulation and the methods for manufacturing and using the same
JP5138856B2 (ja) * 2001-06-20 2013-02-06 武田薬品工業株式会社 錠剤の製造方法
US6766817B2 (en) * 2001-07-25 2004-07-27 Tubarc Technologies, Llc Fluid conduction utilizing a reversible unsaturated siphon with tubarc porosity action
FR2837100B1 (fr) * 2002-03-18 2004-07-23 Flamel Tech Sa Comprimes a bases de microcapsules a liberation modifiee
CN1674877A (zh) * 2002-06-07 2005-09-28 兰贝克赛实验室有限公司 控释的多单位药物释放系统
US7285255B2 (en) * 2002-12-10 2007-10-23 Ecolab Inc. Deodorizing and sanitizing employing a wicking device
GB0302673D0 (en) * 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
ES2261006B1 (es) 2004-06-10 2007-11-01 Laboratorios Rubio, S.A. Pellet multicapa de liberacion controlada de metilfenidato.
US20060051462A1 (en) * 2004-09-03 2006-03-09 Wang Jimmy X Self emulsifying compositions for delivering lipophilic coenzyme Q10 and other dietary ingredients
UA92030C2 (ru) * 2005-08-15 2010-09-27 Солвей Фармасьютикалс Гмбх Фармацевтические композиции регулированного высвобождения нестабильных в кислой среде лекарственных средств
EP2044929A1 (en) * 2007-10-04 2009-04-08 Laboratorios del Dr. Esteve S.A. Oral fast distintegrating tablets

Also Published As

Publication number Publication date
EP2044932A1 (en) 2009-04-08
US20100247641A1 (en) 2010-09-30
NZ584453A (en) 2012-06-29
CN101820866B (zh) 2012-12-05
EP2207534B1 (en) 2014-07-09
RU2500389C2 (ru) 2013-12-10
AU2008306846B2 (en) 2013-09-05
JP5442620B2 (ja) 2014-03-12
RU2010117391A (ru) 2011-11-10
HK1144180A1 (en) 2011-02-02
CN101820866A (zh) 2010-09-01
BRPI0817863A2 (pt) 2015-03-31
IL204815A0 (en) 2010-11-30
ZA201002257B (en) 2011-06-29
JP2010540596A (ja) 2010-12-24
EP2207534A1 (en) 2010-07-21
MX2010003591A (es) 2010-04-21
AU2008306846A1 (en) 2009-04-09
KR20100091956A (ko) 2010-08-19
CA2701556A1 (en) 2009-04-09
WO2009043929A1 (en) 2009-04-09

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