RU2473359C2 - Composition for increasing working performance of sportsmen (versions) - Google Patents

Abstract

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pharmaceutical industry, namely functional compositions necessary for sportsmen specialized in strength sport and for individuals occupied in physically demanding job. The first version of the composition contains ginseng root extract, eleuterococcus root extract, orange skin extract, propolis, L-carnitine, L-citrulline, L-methionine, liquid licorice root and rhizome extract, fructose, preserving agent, sweetening agent, aromatising agent and water. The second version of the composition contains ginseng root extract, eleuterococcus root extract, orange skin extract, propolis, native royal bee, L-carnitine, vitamin B5, vitamin B12, inositol, magnesium gluconate, zinc gluconate, taurine, liquid licorice root and rhizome extract, fructose, preserving agent and water. The third version of the composition contains ginseng root extract, orange skin extract, native royal bee, vitamin B5, vitamin B12, inositol, magnesium gluconate, zinc gluconate, liquid licorice root and rhizome extract, fructose, citric acid, preserving agent, sweetening agent, aromatising agent and water.

EFFECT: said compositions extend the range of products improving working performance and body tolerance.

3 cl, 3 ex

Description

The invention relates to the pharmaceutical industry, and in particular to compositions of a functional purpose, necessary for athletes specializing in power sports, and for people engaged in heavy physical labor. It is known that intense physical labor, including sports, stimulate various body systems. However, the sport of top achievements due to high physical and emotional overload negatively affects the human immune system. It is shown that it is the weakening of the immune system of athletes during peak overloads during intense training and in competitions that leads to a decrease in sports results in competitions.

Known dry nutritional mixture for nutritional nutrition, characterized in that it contains at least one vegetable protein, one water-soluble fat, one carbohydrate, one emulsifier, one flavoring, as well as dietary fiber, succinic acid, L-carnitine and / or its derivatives, selenium on an organic carrier and vitamin mineral premix, (patent RU No. 2306715).

Known in particular are Pectosol pharmaceuticals, a prophylactic containing pectin and microelements, characterized in that it additionally contains pollen, lactose, licorice, nettle, propolis, and calcium stearate and magnesium oxide as a source of microelements. The use of the drug is limited by the presence of pollen - a sufficiently strong allergen.

In addition, the drug is effective only when used in large doses and for a long time. The latter condition makes the use of the drug for athletes undesirable.

This invention is the closest to the proposed technical essence and is taken by us as a prototype.

The technical task of the invention is to increase the pharmacological activity of variants of compositions for use in persons engaged in heavy physical labor, and athletes.

The stated technical problem is solved by creating concentrated solutions with high pharmacological activity and bioavailability, which makes it possible to overcome the state of immunodeficiency in athletes during peak loads on his body due to the optimally selected ratio of components and their properties:

The first version of the composition contains, in addition to licorice, eleutherococcus and propolis, also ginseng root extract, orange peel extract, L-carnitine, L-citrulline, L-methionine, fructose, preservative, sweetener, flavor in the following ratio in wt.%:

Ginseng Root Extract 0.1-7.0

Eleutherococcus root extract 0.1-8

Orange Peel Extract 0.1-18

Propolis 0.5-2

L-carnitine 0.5-6

L-citrulline 0.1-2

L- methionine 0.05-5

Root extract with licorice rhizomes 0.1-2

Fructose 5-28

Preservative 0.01-1.0

Sweetener 0.001-1.5

Fragrance 0.001-0.5

Water rest

The second version of the solution composition contains, in addition to licorice, eleutherococcus and propolis, additionally ginseng root extract, orange peel extract, native royal jelly, L-carnitine, vitamin B5, vitamin B12, inositol, magnesium gluconate, zinc gluconate, taurine, fructose, preservative, sweetener, flavoring in the following ratios in wt.%:

Ginseng Root Extract 0.1-5

Eleutherococcus root extract 0.1-8

Orange Peel Extract 0.1-22

Propolis 0.1-5

Native royal jelly 0.1-3

L-Carnitine 0.5-8

Vitamin B5 0.01-0.1

Vitamin B12 0.0001-0.1

Inositol 0.05-2

Magnesium Gluconate 0.5-18

Zinc Gluconate 0.05-1

Taurine 0.1-3

Root extract with licorice rhizomes 0.05-5

Fructose 1-27

Preservative 0.01-1.0

Sweetener 0.001-1.5

Fragrance 0.001-0.5

Water rest

The third solution composition contains, in addition to licorice, additionally ginseng root extract, orange peel extract, native royal jelly, vitamin B5, vitamin B 12, inositol, magnesium gluconate, zinc gluconate, fructose, preservative, sweetener, flavoring in the following ratios in wt. %:

Ginseng Root Extract 0.1-5

Orange Peel Extract 0.1-22

Native royal jelly 0.1-3

Vitamin B5 0.01-0.1

Vitamin B12 0.0001-0.1

Inositol 0.05-2

Magnesium Gluconate 0.5-18

Zinc Gluconate 0.05-1

Root extract with licorice rhizomes 0.05-5

Fructose 1-27

Citric acid 0.1-10

Preservative 0.01-1.0

Sweetener 0.001-1.5

Fragrance 0.001-0.5

Water rest

Composition No. 1 may contain royal jelly in a lyophilized form, the amount of which is recalculated taking into account the solids content.

As extracts may contain either a thick, or dry, or liquid extract.

The advantages of the present invention include the fact that:

- the activity of the composition is due to the maximum concentration of active compounds in the minimum volume of solvent;

- the subject is a composition that can be used for direct consumption;

- concentrations of active components allow the composition to be used in a minimum volume calculated for a single dose;

- the convenience of the possibility of a single dose of the entire dose (excludes the possibility of skipping the next dose during the day or overdose due to repeated use;

- the composition is designed for the use of a small amount (11 ml) to achieve maximum effect before increased physical activity or playing sports (11 ml bottles are produced). Shelf life 3 years;

- allows you to expand the range of drugs for athletes;

- the composition does not contain doping substances included in the list of WADA, psychotropic substances;

- the concentration of the composition is convenient for inclusion in more diluted preparations (for example, drinks, sprays, syrups, mashed potatoes). Concentrations of active substances are justified by the average daily norm of the physiological needs of the body for concentration and increase the working capacity of the body, improve adaptogenic properties;

- the presence of a polar solvent in the composition allows to increase the bioavailability of active components characterized by hydrophilic properties.

The water used as a solvent can be deionized, purified, injectable and of other quality that is approved for oral use.

Instead of fructose, it is allowed to use other sugar approved for use in the food industry.

The invention is illustrated by the following examples of industrial implementation in a production environment.

An example of a specific implementation of the composition No. 1

Example No. 1

Under sterile conditions, 20% of water is measured, in which the exact amounts of ingredients, 8% fructose, 0.1% orange peel extract, 0.1% eleutherococcus root extract, 0.5% L-carnitine, 0.5% are dissolved in the following sequence propolis, triturated in 0.1% root extract with licorice rhizomes, 0.1% ginseng root extract, 0.1% L-citrulline, 0.05% L-methionine, 01% preservative (0.005% potassium sorbate, 0.005% sodium benzoate), 0.001% sweetener (0.0003% potassium acetyl sulfate, 0.0006% sodium cyclomat, 0.0001% sodium saccharin), 0.001% flavor (natural lemon). They thoroughly homogenize, adjust the volume with water to 100%, mix the resulting solution thoroughly, pass the mixture through a homogenizer under high pressure, filter it and pour it into containers.

Example No. 2

Under sterile conditions, 12% of water is measured, in which the exact amounts of ingredients are dissolved in the following sequence, 28% fructose, 18% orange peel extract, 8% eleutherococcus root extract, 6% L-carnitine, 2% propolis, triturated in 2% liquid extract roots with rhizomes of licorice; 7% ginseng root extract, 2% L-citrulline, 5% L-methionine, 1.0% preservative (0.5% potassium sorbate, 0.5% sodium benzoate), 1.5% sweetener (0.5% potassium acetyl sulfate, 0.5% sodium cyclomat, 0.5% sodium saccharin), 0.5% flavor (natural lemon). Thoroughly homogenize, adjust the volume with water to 100%. The resulting solution is re-mixed thoroughly, the mixture is passed through a homogenizer under high pressure, filtered and poured into containers.

Example No. 3

Under sterile conditions, 25% of deionized water is measured, in which the exact amounts of ingredients are dissolved in the following sequence, 28% fructose, 18% liquid extract of orange peel, 5% dry extract of eleutherococcus root, 5% L-carnitine, 1% propolis, ground in 1 % liquid root extract with licorice rhizomes; 1% thick ginseng root extract, 1% L-citrulline, 1% L-methionine, 0.1%, then 0.1% preservative (potassium sorbate), 0.15% sweetener (stevioside), 0.05% flavor ( natural orange), carefully homogenized, bring the volume of deionized water to 100%. The resulting solution is re-mixed thoroughly, the mixture is passed through a homogenizer under high pressure, filtered and poured into containers.

Example No. 4

Under sterile conditions, 25% of purified water is measured, in which the exact amounts of ingredients are dissolved in the following sequence, 28% sucrose, 18% thick extract of orange peel, 5% liquid extract of eleutherococcus root, 5% L-carnitine, 1% propolis, ground in 1 % liquid root extract with licorice rhizomes; 1% dry ginseng root extract, 1% L-citrulline, 1% L-methionine, 0.1% preservative (sorbic acid), 0.15% sweetener (sucralose), 0.05% flavor (natural raspberry). Thoroughly homogenize, bring the volume of purified water to 100%. The resulting solution is re-mixed thoroughly, the mixture is passed through a homogenizer under high pressure, filtered and poured into containers.

Example No. 5

Under sterile conditions, 25% of injection water is measured, in which the exact amounts of ingredients are dissolved in the following sequence, 28% sucrose, 18% orange peel extract, 5% eleutherococcus root extract, 5% L-carnitine, 1% propolis, triturated in 1% liquid root extract with licorice rhizomes; 1% dry ginseng root extract, 1% L-citrulline, 1% L-methionine, 0.1% magnesium lactate, 0.1% preservative (0.05% potassium sorbate, 0.05% sodium benzoate), 0.15 % sweetener (0.05% potassium acetylsulfate, 0.05% sucralose, 0.05% saccharin sodium), 0.05% flavor (natural orange). Thoroughly homogenize, bring the volume of injection water to 100%. The resulting solution is re-mixed thoroughly, the mixture is passed through a homogenizer under high pressure, filtered and poured into containers.

An example of a specific implementation of the composition No. 2

Example No. 1

Under sterile conditions, water is measured in an amount of 36%, in which the substances are dissolved in the following sequence: 5% fructose, 0.1% extract of orange peel, 0.1% extract of eleutherococcus roots, 0.5% L-carnitine, native royal jelly 0 , 1%, 0.1% taurine, stirred, add 0.1% propolis extract to the main solution with stirring. Add 0.05% inositol, 0.1% ginseng root extract, 0.05% liquid root extract with licorice rhizomes, 0.5% magnesium gluconate, 0.05% zinc gluconate, 0.01% calcium pantothenate (vitamin B5) , 0.0001% cyanocobalamin (vitamin B12), 0.01% preservative (0.005% potassium sorbate, 0.005% sodium benzoate), 0.001% sweetener (0.0003% potassium acetyl sulfate, 0.0006% sodium cyclomat, 0.0001% sodium saccharin), 0.001% flavor (natural lemon). They thoroughly homogenize, adjust the volume with water to 100%, mix the resulting solution thoroughly, pass the mixture through a homogenizer under high pressure, filter it and pour it into containers.

Example No. 2

Under sterile conditions, water is measured in an amount of 12%, in which the substances are dissolved in the following sequence: 5% fructose, 22% orange peel extract, ginseng root extract 0.1%, 8% eleutherococcus root extract, 8% L-carnitine, 3% native royal jelly, 3% taurine, mix, add 5% propolis extract to the main solution with stirring. Add 2% inositol, 5% ginseng root extract, 5% liquid root extract with licorice rhizomes, 18% magnesium gluconate, 1% zinc gluconate, 0.1% calcium pantothenate (vitamin B5), 0.1% cyanocobalamin (vitamin B12) , 1.0% preservative (0.5% potassium sorbate, 0.5% sodium benzoate), 1.5% sweetener (0.5% potassium acetyl sulfate, 0.5% sodium cyclomat, 0.5% sodium saccharin), 0.5% flavor (natural lemon). They thoroughly homogenize, adjust the volume with water to 100%, mix the resulting solution thoroughly, pass the mixture through a homogenizer under high pressure, filter it and pour it into containers.

Example No. 3

Under sterile conditions, deionized water is measured in an amount of 10%, in which the substances are dissolved in the following sequence: 15% fructose, 15% dry extract of orange peel, 3% thick extract of eleutherococcus roots, 0.5% L-carnitine, 0.5% lyophilized royal jelly, 1% taurine, mix, add 5% liquid propolis extract to the main solution with stirring. Add 2% inositol, 5% ginseng root extract, 5% liquid root extract with licorice rhizomes, 10% magnesium gluconate, 1% zinc gluconate, 0.1% calcium pantothenate (vitamin B5), 0.1% cyanocobalamin (vitamin B 12 ), 01% preservative (0.05% potassium sorbate, 0.05% sodium benzoate), 0.15% sweetener (0.05% potassium acetyl sulfate, 0.05% sodium cyclomat, 0.05% saccharin sodium), 0 , 5% flavor (natural orange). They thoroughly homogenize, adjust the volume with deionized water to 100%, mix the resulting solution thoroughly, pass the mixture through a homogenizer under high pressure, filter it and pour it into containers.

Example No. 4

In sterile conditions, injection water is measured in an amount of 30%, in which the substances are dissolved in the following sequence: 15% fructose, 15% orange peel extract, 3% eleutherococcus root extract, 0.5% L-carnitine, 1.0% native royal jelly , 1% L-taurine, stirred, add 5% propolis extract to the main solution with stirring. Add 2% inositol, 5% ginseng root extract, 5% liquid root extract with licorice rhizomes, 10% magnesium gluconate, 1% zinc gluconate, 0.1% calcium pantothenate (vitamin B5), 0.1% cyanocobalamin (vitamin B12) , 0.1% preservative (0.05% potassium sorbate, 0.05% sodium benzoate), 0.15% sweetener (0.05% potassium acetyl sulfate, 0.05% sodium cyclomat, 0.05% sodium saccharin), 0.5% flavor (natural strawberry), thoroughly homogenize, adjust the volume of the solution with injection water to 100%, the resulting solution is thoroughly mixed again, pass the mixture through th ogenizator under high pressure, is filtered and poured into the container.

Example No. 5

Under sterile conditions, purified water is measured in an amount of 20%, in which the substances are dissolved in the following sequence: 15% sucrose, 15% orange peel extract, 3% eleutherococcus root extract, 0.5% L-carnitine, 1.0% native royal jelly , 1% L-taurine, stirred, add 5% propolis extract to the main solution with stirring. Add 2% inositol, 5% ginseng root extract, 5% liquid root extract with licorice rhizomes, 10% magnesium gluconate, 1% zinc gluconate, 0.1% calcium pantothenate (vitamin B5), 0.1% cyanocobalamin (vitamin B12) , 0.1% preservative (0.05% potassium sorbate, 0.05% sodium benzoate), 0.15% sweetener (0.05% potassium acetyl sulfate, 0.05% sodium cyclomat, 0.05% sodium saccharin), 0.5% flavor (natural lemon). Thoroughly homogenize, adjust the volume of the solution with purified water to 100%, mix the resulting solution thoroughly, pass the mixture through the homogenizer under high pressure, filter and pour into containers.

Example No. 6

In sterile conditions, deionized water is measured in an amount of 20%, in which the substances are dissolved in the following sequence: 15% sucrose, 15% orange peel extract, 3% eleutherococcus root extract, 0.5% L-carnitine, 1.0% native royal jelly , 1% L-taurine, stirred, add 5% propolis extract to the main solution with stirring. Add 2% inositol, 5% ginseng root extract, 5% liquid root extract with licorice rhizomes, 10% magnesium gluconate, 1% zinc gluconate, 0.1% calcium pantothenate (vitamin B5), 0.1% cyanocobalamin (vitamin B 12 ), 0.1% preservative (0.05% potassium sorbate, 0.05% sodium benzoate), 0.15% sweetener (0.05% potassium acetyl sulfate, 0.05% sodium cyclomat, 0.05% sodium saccharin) , 0.5% flavor (natural lemon). They thoroughly homogenize, bring the solution volume to 100% with deionized water, mix the resulting solution thoroughly, pass the mixture through a homogenizer under high pressure, filter it and pour it into containers.

An example of a specific implementation of the composition No. 3

Example No. 1

Under sterile conditions, water is measured in an amount of 36%, in which the substances are dissolved in the following sequence: 1% fructose, 0.1% orange peel extract, native royal jelly 0.1%, mixed, 0.05% inositol, 0.1 added % ginseng root extract, 0.05% licorice root extract, 0.5% magnesium gluconate, 0.05% zinc gluconate, 0.01% calcium pantothenate (vitamin B5), 0.0001% cyanocobalamin (vitamin B 12) , 0.01% preservative (0.005% potassium sorbate, 0.005% sodium benzoate), 0.001% sweetener (0.0003% potassium acetyl sulfate, 0.0006% sodium cyclomat, 0.0001% atria saccharin), citric acid 0.1%, 0.001% flavor (lemon natural), thoroughly homogenized, volume adjusted with water to 100%. The resulting solution is re-mixed thoroughly, the mixture is passed through a homogenizer under high pressure, filtered and poured into containers.

Example No. 2

Under sterile conditions, water is measured in an amount of 20%, in which the substances are dissolved in the following sequence: 27% fructose, 22% orange peel extract, 3.0% native royal jelly, add 2% inositol, 5% ginseng root extract, 5% extract roots with licorice rhizomes, 18% magnesium gluconate, 1% zinc gluconate, 0.1% calcium pantothenate (vitamin B5), 0.1% cyanocobalamin (vitamin B 12), 1.0% preservative (0.5% potassium sorbate, 0.5% sodium benzoate), 1.5% sweetener (0.5% potassium acetyl sulfate, 0.5% sodium cyclomat, 0.5% sodium saccharin), 10% citric acid lots, 0.5% flavor (natural lemon), thoroughly homogenize, bring the volume of the solution with water to 100%. The resulting solution is re-mixed thoroughly, the mixture is passed through a homogenizer under high pressure, filtered and poured into containers.

Example No. 3

Under sterile conditions, purified water is measured in an amount of 36%, in which the substances are dissolved in the following sequence: 20% fructose, 10% dry extract of orange peel, native royal jelly 0.2%, mix, add 0.1% inositol, 1% liquid ginseng root extract, 1% thick root extract with licorice rhizomes, 1% magnesium gluconate, 1% zinc gluconate, 0.05% calcium pantothenate (vitamin B5), 0.001% cyanocobalamin (vitamin B12), 0.01% preservative (sorbic acid ), 0.001% sweetener (stevioside), citric acid 0.3%, 0.001% aroma ora (natural orange), thoroughly homogenized, volume adjusted with purified water to 100%. The resulting solution is re-mixed thoroughly, the mixture is passed through a homogenizer under high pressure, filtered and poured into containers.

Example No. 4

In sterile conditions, injection water is measured in an amount of 36%, in which the substances are dissolved in the following sequence: 20% fructose, 10% dry extract of the peel of an orange, native royal jelly 0.2%, mix, add 0.1% inositol, 1% liquid ginseng root extract, 1% dry root extract with licorice rhizomes, 1% magnesium gluconate, 1% zinc gluconate, 0.05% calcium pantothenate (vitamin B5), 0.001% cyanocobalamin (vitamin B12), 0.01% preservative (sorbic acid ), 0.001% sweetener (sucralose), citric acid 0.3%, 0.001% aroma Ator (strawberry natural), thoroughly homogenized, volume adjusted with water injection to 100%, the resulting solution was again thoroughly stirred, the mixture was passed through a homogenizer under high pressure, is filtered and poured into the container.

Example No. 5

Under sterile conditions, 36% deionized water is measured, in which the substances are dissolved in the following sequence: 20% fructose, 10% dry extract of orange peel, native royal jelly 0.2%, mixed, 0.1% inositol, 1% liquid ginseng root extract, 1% dry root extract with licorice rhizomes, 1% magnesium gluconate, 1% zinc gluconate, 0.05% calcium pantothenate (vitamin B5), 0.001% cyanocobalamin (vitamin B12), 0.01% preservative (0.005% potassium sorbate, 0.005% sodium benzoate), 0.001% sweetener (sodium saccharin), limo acid, 0.3%, 0.001% flavor (natural lemon), thoroughly homogenize, adjust the volume with deionized water to 100%, the resulting solution is thoroughly mixed, the mixture is passed through the homogenizer under high pressure, filtered and poured into containers.

In practice, you can make changes and modify the described preferred embodiments of the present invention, without departing from the subject and objectives of the present invention, within the scope of the claimed claims.

L-carnitine and / or its derivatives (for example, propionylcarnitine, acetylcarnitine, palmitoylcarnitine) play an important role in providing energy to the myocardium. They are an indispensable factor in the metabolism of fatty acids, binding to free fatty acids, ensure their transfer through the mitochondrial membrane, inside of which beta-oxidation of fatty acids occurs with the formation of substrates of the Krebs cycle, which is the main source of energy for the myocardium, and also prevent excessive accumulation of free and esterified fatty acids in the cytoplasm of a cell. It has been reliably established that L-carnitine protects the myocardium from ischemia, maintains a sufficient level of ATP in the heart muscle and increases its contractility, and is also an important factor in reducing the risk of developing atherosclerosis and other cardiovascular diseases.

Orange peel extract affects the cardiovascular system, strengthens the walls of blood vessels. It has a cardiotonic effect, activates coronary blood flow, eliminates neurotic and functional disturbances in the rhythm of heart contractions.

Taurine plays a large role in lipid metabolism, helps to normalize the function of cell membranes, optimizes energy and metabolic processes, preserves the electrolyte composition of the cytoplasm (due to the accumulation of potassium and calcium ions), and is part of paired bile acids (taurocholic, taurodeoxycholic), which contribute to the emulsification of fats in intestines. In the brain, it performs the function of a neurotransmitter inhibiting synaptic transmission, has anticonvulsant and cardiotonic activity.

Studies have been conducted on the effects of the compositions on the physical performance of volunteers using the example of running at medium and long distances. The bench experiment consisted in determining the time (duration) of running on a treadmill with a stepwise increasing load to failure, as well as the speed of recovery after it and the state of lipid peroxidation processes of unsaturated fatty acids in the process of performing this work in the experimental and control groups (18 people each each).

Volunteers were selected for approximately the same parameters (gender, age, sports qualifications and other characteristics).

A total of 18 men aged 19 to 26 years were examined. The control group received a placebo 2 times a day for 20 days. The experimental group took the proposed composition according to the composition of examples No. 2 for each option.

Before and after the experiment, the state of working capacity, recovery, the concentration of glucose, protein and urea in the blood, as well as the processes of spontaneous chemiluminescence in the urine and the concentration of malondialdehyde by conventional methods were determined.

Studies were performed in the initial state on the 10th and 20th day of administration, as well as 5 days after stopping the drug. Studies have shown an increase in performance and endurance when taking the proposed compositions on the third day. When taking the composition in no case was an allergic reaction noted.

Example 1

Athlete V. 26 years old, long-distance running, took the composition No. 2, option 1, 1 bottle (11 ml) once a day at night for 3 days. The value of the urea level in the control and after taking the composition was determined. Control 17.1 mg%, after taking 15.2 mg%. A faster recovery of heart rate and blood pressure was noted. The study of ECG and biochemical blood parameters (lactic acid content, ATP, ADP, AMP balance) showed the absence of overfatigue and overvoltage.

A quick recovery of the athlete’s performance, increase of his endurance, acceleration of adaptation to physical activity and extreme environmental factors, increase of the body’s immune resistance were noted.

Example 2

Athlete K., 26 years old, Honored Master of Sports in Athletics (running.), Took the composition No. 2, option 2, 1 bottle (11 ml) once a day at night for 3 days. The value of the urea level in the control and after taking the composition was determined. Control 16.9 mg%, after taking 15.8 mg%. A rapid restoration of efficiency, as well as a gradual increase in its limit, was noted.

Example 3

Athlete E., 24 years old, Honored Master of Sports in Athletics (running), took the composition No. 2, option 3, 1 bottle (11 ml) once a day at night for 3 days. The value of the urea level in the control and after taking the composition was determined. Control 18.9 mg%, after taking 17.8 mg%. Rapid recovery of performance was noted, as well as a gradual increase in the limit of physical activity after taking the composition. Thus, the claimed composition has good taste, is easy to take, the volume and method of use are convenient for swallowing, the amount of active ingredients included in the composition allows a single dose to ensure that the active substance complex enters the body in an amount sufficient to achieve maximum effect. The drug has shown its effectiveness to increase the health of the body. Based on the foregoing, it can be concluded that the proposed composition has several advantages in comparison with the prototype. The technical task is achieved by reducing the time of admission to achieve results and reduce the dose of admission.

Thus, the claimed composite mixture has an effect that increases the efficiency, endurance of the human body.

Claims (3)

1. Composition for improving the performance of athletes, containing propolis, characterized in that it further contains root extract with licorice rhizomes, Eleutherococcus root extract, ginseng root extract, orange peel extract, L-carnitine, L-citrulline, L-methionine, fructose, preservative , sweetener, flavoring and water in the following ratio of components, wt.%:
Ginseng Root Extract 0.1-7.0 Eleutherococcus Root Extract 0.1-8 Orange Peel Extract 0,1-18 Propolis 0.5-2 L-carnitine 0.5-6 L-citrulline 0.1-2 L-methionine 0.05-5 Licorice Root Extract 0.1-2 Fructose 5-28 Preservative 0.01-1.0 Sweetener 0.001-1.5 Flavoring 0.001-0.5 Water Rest 2. A composition for increasing the athletes' working capacity, containing propolis, characterized in that it additionally contains licorice root and root extract extract, Eleutherococcus root extract, ginseng root extract, orange peel extract, native royal jelly, L-carnitine, vitamin B5, vitamin B12, inositol , magnesium gluconate, zinc gluconate, taurine fructose, potassium sorbate, sodium benzoate, potassium acetyl sulfate, sodium cyclomat, sodium saccharin, flavoring, and water in the following ratio, wt.%:
Ginseng Root Extract 0.1-5 Eleutherococcus Root Extract 0.1-8 Orange Peel Extract 0.1-22 Propolis 0.1-5 Native royal jelly 0.1-3 L-carnitine 0.5-8 Vitamin B5 0.01-0.1 Vitamin B12 0.0001-0.1 Inositol 0.05-2 Magnesium Gluconate 0.5-18 Zinc Gluconate 0.05-1 Taurine 0.1-3 Licorice Root Extract 0.05-5 Fructose 1-27 Preservative 0.01-1.0 Sweetener 0.001-1.5 Flavoring 0.001-0.5 Water Rest 3. A composition for increasing the athletes' health, containing root extract with licorice rhizomes, ginseng root extract, orange peel extract, native royal jelly, vitamin B5, vitamin B12, inositol, magnesium gluconate, zinc gluconate, fructose, preservative, sweetener, citric acid, flavoring and water in the following ratio, wt.%:
Ginseng Root Extract 0.1-5 Orange Peel Extract 0.1-22 Native royal jelly 0.1-3 Vitamin B5 0.01-0.1 Vitamin B12 0.0001-0.1 Inositol 0.05-2 Magnesium Gluconate 0.5-18 Zinc Gluconate 0.05-1 Licorice Root Extract 0.05-5 Fructose 1-27 Lemon acid 0.1-10 Preservative 0.01-1.0 Sweetener 0.001-1.5 Flavoring 0.001-0.5 Water Rest