RU2442576C2 - Фармацевтическая комбинация, содержащая 3-(3-диметиламино-1-этил-2-метилпропил)фенол и парацетамол - Google Patents

Фармацевтическая комбинация, содержащая 3-(3-диметиламино-1-этил-2-метилпропил)фенол и парацетамол Download PDF

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Publication number
RU2442576C2
RU2442576C2 RU2008146816/15A RU2008146816A RU2442576C2 RU 2442576 C2 RU2442576 C2 RU 2442576C2 RU 2008146816/15 A RU2008146816/15 A RU 2008146816/15A RU 2008146816 A RU2008146816 A RU 2008146816A RU 2442576 C2 RU2442576 C2 RU 2442576C2
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RU
Russia
Prior art keywords
pain
combination
components
paracetamol
methylpropyl
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RU2008146816/15A
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English (en)
Russian (ru)
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RU2008146816A (ru
Inventor
Петра БЛОМС-ФУНКЕ (DE)
Петра Бломс-Функе
Клаус ШИНЕ (DE)
Клаус ШИНЕ
Original Assignee
Грюненталь Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Грюненталь Гмбх filed Critical Грюненталь Гмбх
Publication of RU2008146816A publication Critical patent/RU2008146816A/ru
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Publication of RU2442576C2 publication Critical patent/RU2442576C2/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2008146816/15A 2006-04-28 2007-04-25 Фармацевтическая комбинация, содержащая 3-(3-диметиламино-1-этил-2-метилпропил)фенол и парацетамол RU2442576C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06008851.5 2006-04-28
EP06008851 2006-04-28

Publications (2)

Publication Number Publication Date
RU2008146816A RU2008146816A (ru) 2010-06-10
RU2442576C2 true RU2442576C2 (ru) 2012-02-20

Family

ID=37025148

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2008146816/15A RU2442576C2 (ru) 2006-04-28 2007-04-25 Фармацевтическая комбинация, содержащая 3-(3-диметиламино-1-этил-2-метилпропил)фенол и парацетамол

Country Status (25)

Country Link
EP (1) EP2012764B1 (no)
JP (2) JP5496653B2 (no)
KR (1) KR101396166B1 (no)
CN (1) CN101431990B (no)
AT (1) ATE494889T1 (no)
AU (1) AU2007247481B2 (no)
BR (1) BRPI0710682B8 (no)
CA (1) CA2650423C (no)
CY (1) CY1111369T1 (no)
DE (1) DE602007011913D1 (no)
DK (1) DK2012764T3 (no)
EC (2) ECSP088793A (no)
ES (1) ES2356093T3 (no)
HK (1) HK1127289A1 (no)
HR (1) HRP20110076T1 (no)
IL (1) IL194883A (no)
MX (1) MX2008013779A (no)
NO (2) NO341602B1 (no)
NZ (1) NZ571442A (no)
PL (1) PL2012764T3 (no)
PT (1) PT2012764E (no)
RU (1) RU2442576C2 (no)
SI (1) SI2012764T1 (no)
WO (1) WO2007128413A1 (no)
ZA (1) ZA200810124B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007012165A1 (de) 2007-03-12 2008-09-18 Grünenthal GmbH Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie des Neuropathieschmerzes
EP2219633A2 (en) * 2007-11-23 2010-08-25 Nectid, Inc. Tapentadol compositions
KR101831616B1 (ko) 2010-06-15 2018-04-04 그뤼넨탈 게엠베하 통증 치료용 약제학적 병용물
MX351584B (es) 2011-03-04 2017-10-20 Gruenenthal Gmbh Formulacion farmaceutica acuosa de tapentadol para administracion oral.
US20120225951A1 (en) * 2011-03-04 2012-09-06 Gruenenthal Gmbh Parenteral Administration of Tapentadol
EP2680834B1 (en) 2011-03-04 2017-10-18 Grünenthal GmbH Semisolid aqueous pharmaceutical composition containing tapentadol
US9320729B2 (en) 2012-05-18 2016-04-26 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-flouro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative
US20130310435A1 (en) 2012-05-18 2013-11-21 Gruenenthal Gmbh Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4,9' -dihydro-3'H-spiro[cyclohexane-1,1' -pyrano[3,4,b]indol]-4-amine and Paracetamol or Propacetamol
US9855286B2 (en) 2012-05-18 2018-01-02 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-di methyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a salicylic acid component
US20130310385A1 (en) 2012-05-18 2013-11-21 Gruenenthal Gmbh Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine and Antidepressants
EP2808319A1 (en) 2013-05-31 2014-12-03 Arevipharma GmbH 3-[3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol resin complex
LT3273953T (lt) 2015-03-27 2019-02-25 Grünenthal GmbH Stabili kompozicija, skirta tapentadolio skyrimui parenteriniu būdu
EP3515412A1 (en) 2016-09-23 2019-07-31 Grünenthal GmbH Stable formulation for parenteral administration of tapentadol
EP3585370A1 (en) 2017-02-23 2020-01-01 Grünenthal GmbH Tapentadol as local anesthetic

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4426245A1 (de) 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
PE20030527A1 (es) * 2001-10-24 2003-07-26 Gruenenthal Chemie Formulacion farmaceutica con liberacion retardada que contiene 3-(3-dimetilamino-1-etil-2-metil-propil) fenol o una sal farmaceuticamente aceptable del mismo y tabletas para administracion oral que la contienen
EP1685829B1 (de) * 2002-11-22 2008-04-09 Grünenthal GmbH Verwendung von (1RS,3RS,6RS)-6-dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexan-1,3-diol zur Behandlung von Entzündungsschmerz

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
РЛС Энциклопедия лекарств 2004-11. - М.: ООО "РЛС-2004", с.678. БЕЛИКОВ В.Г. Фармацевтическая химия в двух частях, 1 Общая фармацевтическая химия. - М.: Высшая школа, 1993, с.43-47. *

Also Published As

Publication number Publication date
BRPI0710682A2 (pt) 2011-08-23
PL2012764T3 (pl) 2011-04-29
ES2356093T3 (es) 2011-04-04
HRP20110076T1 (hr) 2011-02-28
KR101396166B1 (ko) 2014-05-27
EP2012764A1 (en) 2009-01-14
JP2009535313A (ja) 2009-10-01
KR20090006219A (ko) 2009-01-14
PT2012764E (pt) 2011-02-02
JP5496653B2 (ja) 2014-05-21
AU2007247481B2 (en) 2013-02-14
MX2008013779A (es) 2008-11-14
CN101431990A (zh) 2009-05-13
AU2007247481A1 (en) 2007-11-15
CY1111369T1 (el) 2015-08-05
ZA200810124B (en) 2009-08-26
NO341602B1 (no) 2017-12-11
HK1127289A1 (en) 2009-09-25
CN101431990B (zh) 2011-08-03
DK2012764T3 (da) 2011-02-28
SI2012764T1 (sl) 2011-03-31
CA2650423A1 (en) 2007-11-15
NO20171831A1 (no) 2008-10-28
EP2012764B1 (en) 2011-01-12
BRPI0710682B1 (pt) 2020-09-24
ECSP17000643A (es) 2018-06-30
IL194883A (en) 2012-10-31
NO343505B1 (no) 2019-03-25
IL194883A0 (en) 2009-08-03
CA2650423C (en) 2014-08-12
JP2013213045A (ja) 2013-10-17
ATE494889T1 (de) 2011-01-15
NZ571442A (en) 2011-09-30
RU2008146816A (ru) 2010-06-10
BRPI0710682B8 (pt) 2021-05-25
WO2007128413A1 (en) 2007-11-15
DE602007011913D1 (de) 2011-02-24
NO20084542L (no) 2008-10-28
ECSP088793A (es) 2008-11-27

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