RU2394556C1 - Humic concentrate, containing humic acids, method of obtaining it and composition for head hair and skin care - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: invention relates to field of cosmetology, more specifically to composition for head hair and skin care based on humic concentrate which represents product of peat processing with sodium or potassium hydroxide solution with activation with air oxygen in process of barbotage and further neutralisation with citric or acetic acid solution, which contains absolutely dry substance, wt %: humic acids not less than 2.8, lipid fraction 2.7-2.9, ash components not less than 0.09%, - with pH 5.5-6.5.

EFFECT: invention allows to obtain composition for head hair and skin care with improved consumer properties, stimulating hair growth at the stage of alopecia and ensuring restoration of hair on sections with sparse or no hair with extended indications for application including endured chemical and radio therapy.

5 cl, 1 tbl, 18 ex

Description

The group of inventions relates to the cosmetics industry and relates to cosmetics for hair and scalp based on humic concentrates obtained from peat.

Humic substances are widespread in nature and make up a significant part of such natural humite as peat. A mixture of purified humic substances with a high content of humic acids is a complex of biologically active substances (BAS), the composition and effect of which depend on the method of preparation.

Known stimulator of plant growth from peat, obtained by countercurrent extraction of humic acids of peat with an aqueous solution of an alkaline agent in several stages in a multi-section extractor with periodic multi-stage extraction [Pat. 2078504 RF, 6 IPC A01N 61/00. A method of obtaining a plant growth stimulator].

The method is difficult to implement.

A known method of producing humic concentrate by electrolysis of an aqueous alkaline suspension [US Pat. 2175651 of the Russian Federation. A method of obtaining a humic-mineral concentrate].

The method is applicable to brown coals, but not to peat, where the percentage of initial humates is lower.

A known method of producing humic concentrate by electrolysis of an aqueous alkaline suspension with the provision of an acid module in the pH range of 9-12 [US Pat. 2319683 of the Russian Federation. A method of obtaining a humic-mineral concentrate].

Methods of producing humic concentrates, involving one or another use of electrochemical plants: electrolysis, low-frequency oscillation, cavitating vibrational jets, require large operating costs, are energy-intensive.

The above humic concentrates are obtained using technologies that imply further use of the product for agricultural needs (as a plant growth stimulator as a fertilizer). High pH values of the extracts limit their scope and make them toxic when used in the required amounts for cosmetic purposes.

A known method for the allocation of humic acids by acidification to a pH below 3 [A.S. No. 169112 USSR, MKI S07C 63/33].

The biological activity of such extracts decreases with the irreversible coagulation of colloids, and the toxicity of the product increases.

At the same time, the valuable properties of humic acids and their derivatives allow their use in medicine, cosmetology.

Humates - a mixture of highly purified humic substances with a high content of humic acids - have a bactericidal effect, the ability to positively change metabolic processes, increase the mitotic activity of cells [Pat. 2235548 RF, IPC. Wound healing agent].

Known cosmetic hair care product that contains an extract of humic acids (TU RB 100217-002-2000), camphor, menthol, water-alcohol plant extracts, preservatives, vitamins A, C, B ₆ , H, PP, B ₁ B ₅ , F, E, while preservatives contain nipagin, or nipazole, or a caton, and as plant materials, the product contains hops, calendula, chamomile, St. John's wort, sage, eucalyptus, burdock, nettle, calamus, plantain, juniper, green tea, birch leaves, kelp and fucus. The tool enhances the metabolism in the skin, helps strengthen and grow hair, prevents the formation of dandruff, has a tonic, healing, regenerating effect on the skin [Pat. 2180210 RF, 7 IPC A61K 7/06. Hair Care Cosmetic]. The composition is rubbed into the scalp before washing the hair or applied to washed and dried hair. Do a wrap (warm cap) for 30-60 minutes.

The disadvantage of this tool is its multicomponent nature and the fact that after its use, detergents are used, mainly shampoos, which are washed off the surface and washed off the applied skin from the scalp, drastically reducing their effectiveness.

The closest analogues to the proposed solutions are humic concentrate - a biostimulator from peat (BST), allowed as a stimulator of hair growth in a concentration of not more than 0.6%, a method for producing this concentrate and a composition based on BST.

The technology of such a humic concentrate suitable for cosmetology purposes (TU 214-1-801-809) includes a method for the production of feed additives for livestock and poultry developed at the All-Union Research Institute of Peat Industry [Peat Handbook / Ed. A.V. Lazareva and S.S. Korchunova. - M .: Nedra, 1982. - S.555-556]. This feed additive after additional treatment with alcohol is used in cosmetology [Patent No. 2045948 of the Russian Federation, 6 IPC 7/06. Hair Growth Stimulator].

Thus, the method for producing humic concentrate consists of two labor-intensive stages:

1. peat processing to obtain a feed additive;

2. processing feed additives to obtain BLS.

Stage 1. Oxidation of air with oxygen at elevated temperature (200-225 ° C) and pressure (3.5 MPa) for 3 hours in an aqueous-alkaline medium, repeated washing of the resulting mass from chemicals (alkali), drying of the washed mass.

During long-term processing of peat under harsh conditions, the natural bioactive components of the initial peat are partially destroyed - the humic complex, phytosterols, polysaccharides, lipids, but low molecular weight acids, secondary products of decomposition, oxidation and polymerization are formed, which deteriorate the quality of the blasting agent. Due to the high content of secondary products, the amount of BLS in a final lotion type product is limited. The low content of BST in the composition for strengthening hair - not more than 0.6 wt.% - reduces the effectiveness of the drug when it affects the scalp. Repeated washing with water of hydrolyzed mass leads to the formation of a large amount of wastewater.

Stage 1 technology is multi-stage, energy-intensive, water-intensive, environmentally inappropriate (95% of waste). The total yield of the product does not exceed 5% (on a dry matter basis), and the feed additive obtained by this method is expensive and cannot be sold. All this led to the fact that the production of the additive was discontinued, as did the previously produced BST.

Stage 2. The feed additive is loaded into a flask under reflux at a ratio of product (wt.): 96% ethanol (vol.) = 1: 100 and boiled in a water bath for 1 hour. The resulting suspension of dark brown color is defended, the upper layer - liquid - is decanted from the precipitate and filtered at 20-30 ° C, the filtrate is diluted with water 2 times.

The disadvantages of the second stage include multistage and large losses of BLS and alcohol during the filtration of fine sediment. The filtrate yield does not exceed 20% (in terms of dry matter).

Thus, the total loss of feedstock is more than 99%: the yield of the feed additive is up to 5%, the dry matter yield for the lotion is 20% of 5%, total - 1%.

As follows from the above description, the method itself and each of its stages are laborious and multi-stage. The yield of humic concentrate is low - about 1%.

The concentrate itself, due to hard processing, includes secondary products of decomposition, oxidation and polymerization, which degrade quality.

Lotion - a stimulator of hair growth from peat is used for round-shaped, androgen and seborrheic alopecia and has the following composition, wt.%: BST (peat biostimulator) - 0.015-0.600; rectified ethyl alcohol (90-96%) - 40.0-50.0; water - the rest [Patent No. 2045948 of the Russian Federation, 6 IPC 7/06. Hair Growth Stimulator].

Due to the high content of harmful secondary products, the amount of BLS in the final lotion type product is limited - not more than 0.6 wt.%.

The objective of the proposed group of inventions is to obtain from peat a technologically simple method of humic concentrate suitable for use in cosmetology. Improving the yield and quality of the humic concentrate, the maximum preservation of the native humic complex. Creating a product (composition) for simple hair and scalp care, expanding the range of such products, expanding indications for their use.

The problem is solved in that the humic concentrate containing humic acids is a product of treating peat with a solution of sodium hydroxide or potassium when activated with oxygen in the process of bubbling and subsequent neutralization with a solution of weak organic acid, containing on a completely dry substance, wt.%: Humic acids are not less than 2.8, lipid fraction 2.7-2.9, ash components not less than 0.09%, having a pH of 5.5-6.5 and suitable as an active ingredient for hair and scalp care products.

The problem is also solved by the fact that the method for producing a humic concentrate containing humic acids consists in wetting peat in a ratio of 1: (4-6), using a 10% solution of NaOH or KOH as an alkaline agent, processing is carried out at at a temperature not lower than 60 ° C, activation is carried out with oxygen in the process of bubbling with a total alkaline hydrolysis of 2 to 4 hours, the liquid fraction is separated and neutralized with an aqueous solution of citric (L) or acetic (U) acid to a pH of 5.5-6, 5.

The problem is also solved in that the composition for hair and scalp based on bioactive peat product, including an aqueous solution of the humic complex, as a humic complex contains a humic concentrate according to claim 1 in an amount of 1.5-50.0 wt.%, Having on absolutely dry matter, wt.%: humic acids not less than 2.8, lipid fraction 2.7-2.9, ash components not less than 0.09%, - having a pH of 5.5-6.5 and representing a product treating peat with sodium or potassium hydroxide upon activation with atmospheric oxygen and subsequent neutralization of the solution m citric or acetic acid.

The problem is also solved by the fact that the composition additionally includes a preservative, perfume (both according to the manufacturer’s ND or import) and water (GOST 6709 or SanPiN 2.1.4.1074-01, GOST R 51232) with the preferred ratio of components, wt.%:

Humic concentrate according to claim 1 1,5-5,0 Preservative 0.3 Perfume 0.1 Distilled or Drinking Water up to 100.

The problem is also solved by the fact that the composition, additionally comprising a preservative, perfume and water, contains ethyl alcohol as a preservative in the preferred ratio of components, wt.%:

Humic concentrate according to claim 1 - 1.5-5.0 Ethanol - 20.0 Perfume - 0.1 Distilled or Drinking Water - up to 100.

Examples 1-12. Peat (TU 0392-003-40830869-03 or TU 0391-002-49017785-2003) in an amount of 30 kg is loaded into a reactor equipped with a bottom fitting, a stirrer, a heating jacket and a bubbler.

150 l of water are poured into the reactor at a temperature of 15-20 ° C and stirred for 20 minutes. 3 l of a 10% aqueous solution of sodium or potassium hydroxide are added to the contents of the reactor with stirring and alkaline hydrolysis is carried out for 40-60 minutes at a temperature not lower than 60 ° C, the process is continued at the same temperature and activated with oxygen in the process of bubbling to 2-4 hours. Then the contents of the reactor through the lower fitting is fed to the filter. The filtrate is neutralized with an aqueous solution of citric or acetic acid to a pH of 5.5-6.5.

The yield of humic concentrate is 10-67% of peat.

Examples of the method are summarized in table 1.

Humic concentrate is a product used in the form of lotion.

From the data given in the table it is seen that the humic concentrate is obtained under mild conditions: the long and energy-intensive stage of high-temperature oxidation is excluded; alkaline hydrolysis and activation of the process are combined due to the supply of oxygen during bubbling; alkaline hydrolysis is carried out at atmospheric pressure; It is not necessary to carry out multiple washing (waste water), drying, additional processing of solid residue. Mild process conditions allow the preservation of biologically active substances in humic concentrate; the yield of the target product is significantly increased. Salts of humic and other natural high molecular weight acids of the lipid fraction, along with macro- and microelements, nourish the hair cuticles and have a beneficial effect on hair growth and strengthening.

Example 13. According to the invention, a composition such as a lotion is prepared as follows. The humic concentrate isolated from peat according to the proposed technology is mixed with other components of the lotion in the formulation ratios in a reactor with a stirrer at a temperature of 10-30 ° C.

Unlike the closest analogue, the humic concentrate does not require additional alcohol treatment (see stage 2).

Up to 50% of humic concentrate can be introduced into the composition, however, 1.5-5.0% in terms of the dry matter of the concentrate is necessary and preferred.

Lotion with humic concentrate is applied to the scalp and hair after washing the head, it is not required to rinse.

The effect of using the Compound is confirmed by examples of testing in a clinic in St. Petersburg (allowed by the Federal Service for Supervision of Consumer Rights Protection and Human Welfare).

Example 14. Androgenic and seborrheic alopecia.

The lotion prepared as shown in the recipe was tested on 22 patients aged 21 to 55 years. Presence of baldness from 3 months to 15 years, in most patients 3-4 years. Of the 22 people, 15 are practically healthy, the rest have a different psychological pathology. A positive effect was observed in 82% of patients (18 people), in the rest (4 people) - no effect.

Example 15. Fatty seborrhea, hair loss.

The lotion was tested on 15 patients aged 18 to 55 years. In all cases, patients noted an improvement in the condition of the hair, a decrease in their loss, lack of dandruff, and after a two-week course of application, an improvement in the condition of the scalp and hair strengthening. All patients noted the ability of the lotion to fix the hair for a long time (up to 7 days).

Example 16. Circular baldness.

The lotion was tested on 10 women and 4 men of various ages suffering from circular baldness. The duration of the disease ranged from 3 months to 15 years. A positive effect after a month of applying the lotion was observed in 80% of patients, which was expressed in the following: in the places of application of the lotion a cosmetically satisfactory growth of cannon hair of natural or gray color appeared.

Example 17. Patients (30 people) aged 18 to 40 years, suffering from increased hair loss and the presence of dandruff associated with prolonged use of drugs, nervous overload, smoking or malnutrition.

A lotion was used to strengthen the hair for 2 weeks - one month. All patients noted a positive effect from the use of the lotion: severe hair loss stopped, dandruff disappeared. Patients noted rapid hair growth, good fixation of hairstyles when using lotion, the effect of "thicker hair" - a more voluminous mass of hair.

Example 18. Patients (6 people) who have lost scalp after a course of chemical (3 people) or radiation (3 people) therapy.

Used lotion for 2 weeks. At the same time, the scalp was not only restored, but, as the patients noted, “the hair became thicker” in 100% of cases. Patients noted a good fixation of hairstyles.

The results of the studies showed that the composition shows a pronounced effect in all tests. The increased content of the humic complex against the well-known biostimulant from peat allows you to additionally obtain the effect of fixing the hairstyle and cosmetic effect - the state of "splendor and increase in hair mass." The lotion is well tolerated by all patients, does not cause allergies, does not have an irritating effect and sensitizing properties, does not cause visible changes in the skin, and is easy to use.

The proposed inventions meet the characteristic “inventive step”, since the effectiveness of the proposed soft method for producing a new humic complex from plant materials for cosmetology is not obvious; the possibility of creating an independent product - humic concentrate (TU 9154-023-79774070-2008); as well as high efficiency when expanding indications for the use of a new lotion produced using the created humic complex, an additional effect of fixing the hairstyle.

It can be assumed that the composition additionally exhibits the properties of an immunostimulant and antioxidant.

The proposed invention meets the sign of "industrial applicability", as evidenced by examples of implementation.

The proposed inventions meet the sign of “novelty”, since a humic concentrate with a humic acid content of at least 2.8% was not previously known and described for cosmetology purposes, the method for its preparation and the composition proposed in the solutions.

To obtain humic concentrate from peat, a newly created soft technology is used, which consists in alkaline hydrolysis of peat product in an aqueous medium with simultaneous activation of atmospheric oxygen and subsequent neutralization of the composition by acidification to pH 5.5-6.5. The remainder of peat after hydrolysis and filtration is not a waste product, but is used as fertilizer or mulch, as it does not contain harmful components, i.e. the technology is environmentally friendly.

The humic concentrate contains not only the humic complex, but also all the active substances of the original peat: lipids (including salts of high molecular fatty acids and phytosterol), minerals. When treated with acetic or citric acid, additional useful acetates or citrates are formed.

Minimized due to the mild conditions of hydrolysis of the amount of secondary products of degradation of peat can significantly increase the content of the humic complex and other biologically active substances in the proposed composition and increase its effectiveness.

The proposed group of inventions allows to obtain a composition for hair and scalp care with improved consumer properties, to expand the range of products for the care of the scalp, stimulating hair growth at the stage of baldness and providing restoration of hair in areas of rarefaction or lack of hair with extended indications for use , including after chemical or radiation therapy.

Bioactive additives from biomass of wood, algae and / or other plant materials can be additionally introduced into the composition.

The composition is obtained from available domestic raw materials.

As a raw material for the production of humic concentrate, various peat products, sapropel or bottom sludge can be used.

Table 1 Examples of practical implementation of the method and characteristics of the humic concentrate Options Experiment Number one 2 3 four 5 6 7 8 9 10 eleven 12 The ratio of the number of peat and water 1: 5 1: 6 1: 5 1: 4 1: 5 1: 5 1: 5 1: 6 1: 5 1: 4 1: 5 1: 5 Temperature ° C 80 80 one hundred 80 60 80 80 80 one hundred 80 60 80 Time, hour. 3 3 3,5 3 four 2 3 3 3,5 3 four 2 The yield of HA to the initial peat,% 60 67 61 10 61 62 60 67 61 10 61 62 Mass fraction of humic acids,% 4.8 3.9 4.7 3.2 4,5 2,8 4.8 3.9 4.7 3.2 4,5 2,8 Mass fraction of ash substances,% 1,6 0.6 1.4 0.09 1,2 0.7 1,6 0.6 1.4 0.1 1,2 0.7 Mass fraction of lipid fraction,% 2.9 2,8 2,8 2.7 2.7 2,8 2,8 2.9 2,8 2.7 2,8 2.7 Acid L L L L L L L At At At At At pH 5.5 5.8 5,6 5.8 5.5 5,6 5.5 5.8 5,6 5.8 6.5 5,6

Claims (5)

1. Humic concentrate containing humic acids, suitable as a hair and scalp care product and obtained as a result of peat treatment with an alkaline agent, characterized in that the humic concentrate is a product of peat treatment with a solution of sodium or potassium hydroxide when activated with atmospheric oxygen the process of bubbling and subsequent neutralization with a solution of citric or acetic acid, containing on absolutely dry matter, wt.%: humic acids not less than 2.8, lipid fraction 2.7-2.9, ash to mponentov not less than 0.09%, - having a pH of 5.5-6.5. 2. A method of obtaining a humic concentrate containing humic acids, suitable as a means for hair and scalp care, by treating peat with an alkaline agent, characterized in that peat is poured with water at a temperature of (15-20) ° C in a ratio of 1 :( 4-6) and stirred for 20 minutes, 10% NaOH or KOH solution is used as the alkaline agent, the treatment is carried out at atmospheric pressure for 40-60 minutes at a temperature not lower than 60 ° C, the process is continued at the same temperature and oxygen activation in Processes bubbling at a total current of alkali hydrolysis of from 2 to 4 hours, the liquid fraction is separated and neutralized with aqueous citric or acetic acid to pH 5.5-6.5. 3. Composition for hair and scalp care based on a humic concentrate containing humic acids, suitable as a means for hair and scalp care, characterized in that it contains humic concentrate according to claim 1 in an amount of (1.5-50 , 0) wt.%, Which is a product of peat treatment with a solution of sodium or potassium hydroxide when activated with oxygen in the process of bubbling and subsequent neutralization with a solution of citric or acetic acid, containing absolutely dry matter, wt.%: Humic acids not m She 2.8, 2.7-2.9 lipid fractions, ash components is not less than 0.09%, - having a pH of 5.5-6.5. 4. The composition according to claim 3, characterized in that it further includes a preservative, perfume and water with a preferred ratio of components, wt.%:
Humic concentrate according to claim 1 1,5-5,0 Preservative 0.3 Perfume 0.1 Distilled or Drinking Water up to 100 5. The composition according to claim 3, characterized in that it further includes a preservative, perfume and water, and as a preservative contains ethyl alcohol with a preferred ratio of components, wt.%:
Humic concentrate according to claim 1 1,5-5,0 Ethanol 20,0 Perfume 0.1 Distilled or Drinking Water up to 100