RU2393224C2 - Полипептиды с противомикробной активностью и кодирующие их полинуклеотиды - Google Patents

Полипептиды с противомикробной активностью и кодирующие их полинуклеотиды Download PDF

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Publication number
RU2393224C2
RU2393224C2 RU2007121712/13A RU2007121712A RU2393224C2 RU 2393224 C2 RU2393224 C2 RU 2393224C2 RU 2007121712/13 A RU2007121712/13 A RU 2007121712/13A RU 2007121712 A RU2007121712 A RU 2007121712A RU 2393224 C2 RU2393224 C2 RU 2393224C2
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RU
Russia
Prior art keywords
polypeptide
sequence
antimicrobial
amino acids
seq
Prior art date
Application number
RU2007121712/13A
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English (en)
Russian (ru)
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RU2007121712A (ru
Inventor
Пер Хольсе МЮГИНН (DK)
Пер Хольсе Мюгинн
Могенс Триер ХАНСЕН (DK)
Могенс Триер ХАНСЕН
Марианна Винн СЕРЕНСЕН (DK)
Марианна Винн СЕРЕНСЕН
Дорте САНВАНГ (DK)
Дорте Санванг
Original Assignee
Новозимс Эдениум Байотек А/С
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of RU2007121712A publication Critical patent/RU2007121712A/ru
Application granted granted Critical
Publication of RU2393224C2 publication Critical patent/RU2393224C2/ru

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Botany (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
RU2007121712/13A 2004-11-12 2005-11-11 Полипептиды с противомикробной активностью и кодирующие их полинуклеотиды RU2393224C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200401744 2004-11-12
DKPA200401744 2004-11-12

Publications (2)

Publication Number Publication Date
RU2007121712A RU2007121712A (ru) 2008-12-20
RU2393224C2 true RU2393224C2 (ru) 2010-06-27

Family

ID=35559391

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2007121712/13A RU2393224C2 (ru) 2004-11-12 2005-11-11 Полипептиды с противомикробной активностью и кодирующие их полинуклеотиды

Country Status (17)

Country Link
EP (1) EP1812571A1 (pt)
JP (1) JP5038144B2 (pt)
KR (1) KR20070086065A (pt)
CN (1) CN101098964B (pt)
AP (1) AP2007003991A0 (pt)
AR (1) AR051489A1 (pt)
AU (1) AU2005304115B2 (pt)
BR (1) BRPI0517477A (pt)
CA (1) CA2587449A1 (pt)
IL (1) IL183057A0 (pt)
MX (1) MX2007005520A (pt)
NO (1) NO20072966L (pt)
NZ (1) NZ555039A (pt)
RU (1) RU2393224C2 (pt)
TW (1) TW200621284A (pt)
WO (1) WO2006050737A1 (pt)
ZA (1) ZA200704620B (pt)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012102645A2 (en) 2011-01-27 2012-08-02 «Garmonia», Ltd. Peptide pharmaceutical composition, means for treatment of helicobacter pylori induced gastroduodenal diseases on the basis thereof, and a method of use thereof
RU2803121C2 (ru) * 2018-03-29 2023-09-06 Контрафект Корпорейшн Полипептидные конструкции лизин-противомикробный пептид (amp), лизины, выделенные полинуклеотиды, кодирующие их, а также варианты их применения
US11773140B2 (en) 2018-03-29 2023-10-03 Contrafect Corporation Gram-negative lysin-antimicrobial peptide (AMP) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof in human serum

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008532533A (ja) * 2005-03-16 2008-08-21 ノボザイムス アクティーゼルスカブ 糸状菌におけるデフェンシンの組換え発現
CA2720380A1 (en) * 2008-04-04 2009-10-08 Novozymes Adenium Biotech A/S Use of defensins against meningitis
GB201016733D0 (en) * 2010-10-05 2010-11-17 Novabiotics Ltd Compounds and their use
US8958867B2 (en) * 2011-08-29 2015-02-17 Infraredx, Inc. Detection of lipid core plaque cap thickness
WO2019016043A1 (en) 2017-07-17 2019-01-24 Adenium Biotech Aps PEPTIDES HAVING ANTIBIOTIC POWERS AGAINST MYCOBACTERIUM TUBERCULOSIS
CN112794892B (zh) * 2019-11-13 2022-09-09 中国科学院动物研究所 一种抗真菌肽突变体及其制备方法和应用
CN112724212B (zh) * 2020-12-30 2022-03-18 山西大学 藜麦蛋白在抗植物病菌中的应用
CN114703166B (zh) * 2022-04-29 2023-07-28 西北农林科技大学 一种假结核耶尔森氏菌抗真菌蛋白、应用及分离纯化方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2695392B1 (fr) * 1992-09-04 1994-10-14 Centre Nat Rech Scient Peptides possédant notamment des propriétés antibactériennes, leur procédé d'obtention, et leurs applications biologiques.
WO1999065506A2 (en) * 1998-06-12 1999-12-23 Micrologix Biotech Inc. Cancer therapy with indolicidin or cationic peptides and their polymer conjugates
US6777592B2 (en) * 2000-04-14 2004-08-17 E.I. Du Pont Denemours And Company Arthropod defensins of Scolopendra canidens, Vaejovis carolinianus, and Argiope spp.
JP2004505360A (ja) * 2000-07-25 2004-02-19 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ Uiベースのホームネットワークのブリッジング
CN1177055C (zh) * 2001-01-19 2004-11-24 山东大学 家蝇抗菌肽基因及其克隆方法
US7319087B2 (en) * 2001-05-04 2008-01-15 Novozymes A/S Antimicrobial polypeptide from Aspergillus niger

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EUROPEAN JOURNAL OF BIOCHEMISTRY, vol.209, no.3, 1992, p.977-984. *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012102645A2 (en) 2011-01-27 2012-08-02 «Garmonia», Ltd. Peptide pharmaceutical composition, means for treatment of helicobacter pylori induced gastroduodenal diseases on the basis thereof, and a method of use thereof
RU2803121C2 (ru) * 2018-03-29 2023-09-06 Контрафект Корпорейшн Полипептидные конструкции лизин-противомикробный пептид (amp), лизины, выделенные полинуклеотиды, кодирующие их, а также варианты их применения
US11773140B2 (en) 2018-03-29 2023-10-03 Contrafect Corporation Gram-negative lysin-antimicrobial peptide (AMP) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof in human serum
RU2804774C2 (ru) * 2018-03-29 2023-10-05 Контрафект Корпорейшн Происходящие из бактериофагов противомикробные полипептиды и их применение против грамотрицательных бактерий

Also Published As

Publication number Publication date
EP1812571A1 (en) 2007-08-01
RU2007121712A (ru) 2008-12-20
AR051489A1 (es) 2007-01-17
KR20070086065A (ko) 2007-08-27
AU2005304115B2 (en) 2010-11-18
ZA200704620B (en) 2008-09-25
CN101098964B (zh) 2013-03-20
IL183057A0 (en) 2007-09-20
MX2007005520A (es) 2007-07-09
AP2007003991A0 (en) 2007-06-30
NZ555039A (en) 2009-09-25
BRPI0517477A (pt) 2008-10-07
JP5038144B2 (ja) 2012-10-03
WO2006050737A1 (en) 2006-05-18
CN101098964A (zh) 2008-01-02
NO20072966L (no) 2007-08-10
CA2587449A1 (en) 2006-05-18
JP2008519585A (ja) 2008-06-12
TW200621284A (en) 2006-07-01
AU2005304115A1 (en) 2006-05-18

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Effective date: 20141112