RU2385718C2 - Лечение угрей с использованием производных 5-аминолевулиновой кислоты - Google Patents
Лечение угрей с использованием производных 5-аминолевулиновой кислоты Download PDFInfo
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- RU2385718C2 RU2385718C2 RU2007115601/15A RU2007115601A RU2385718C2 RU 2385718 C2 RU2385718 C2 RU 2385718C2 RU 2007115601/15 A RU2007115601/15 A RU 2007115601/15A RU 2007115601 A RU2007115601 A RU 2007115601A RU 2385718 C2 RU2385718 C2 RU 2385718C2
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- Prior art keywords
- ala
- acne
- photosensitizer
- ester
- ether
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/0616—Skin treatment other than tanning
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
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- A61P17/00—Drugs for dermatological disorders
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Semiconductor Lasers (AREA)
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| GB0525504D0 (en) | 2005-12-14 | 2006-01-25 | Bristol Myers Squibb Co | Antimicrobial composition |
| US20110224598A1 (en) * | 2010-03-12 | 2011-09-15 | Daniel Barolet | Radiant near infrared light emitting diode exposure as skin preparation |
| GB0609809D0 (en) * | 2006-05-17 | 2006-06-28 | Photocure Asa | Product |
| KR100796450B1 (ko) | 2006-06-29 | 2008-01-22 | 전남대학교산학협력단 | 5-아미노레불린산의 불포화 알킬 에스터 및 약학적으로허용되는 그의 염, 이의 제조방법 및 이의 용도 |
| GB0700580D0 (en) * | 2007-01-11 | 2007-02-21 | Photocure Asa | Use |
| WO2009003173A1 (en) | 2007-06-27 | 2008-12-31 | The General Hospital Corporation | Method and apparatus for optical inhibition of photodymanic therapy |
| JP2011506425A (ja) * | 2007-12-14 | 2011-03-03 | フォトデルマ エスアー | 治療的及び美容的方法に有用な新規化合物 |
| GB0823265D0 (en) * | 2008-12-20 | 2009-01-28 | Convatec Technologies Inc | Antimicrobial Composition |
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| GB0900461D0 (en) | 2009-01-12 | 2009-02-11 | Photocure Asa | Photodynamic therapy device |
| CN102458388B (zh) | 2009-06-11 | 2016-09-28 | 光治疗Asa公司 | 半固体组合物及药物制品 |
| JP2013521251A (ja) | 2010-03-01 | 2013-06-10 | フォトキュア エイエスエイ | 美容組成物 |
| EP2585111A1 (en) | 2010-06-23 | 2013-05-01 | Photocure ASA | Hyperosmotic preparations comprising 5 -amino levulinic acid or derivative as photosensitizing agent |
| BR112013000613A2 (pt) | 2010-07-09 | 2016-06-28 | Photocure Asa | composições secas e dispositivos que contêm tais composições secas |
| US9572880B2 (en) | 2010-08-27 | 2017-02-21 | Sienna Biopharmaceuticals, Inc. | Ultrasound delivery of nanoparticles |
| PL3222266T3 (pl) | 2010-08-27 | 2018-10-31 | Sienna Biopharmaceuticals, Inc. | Kompozycje i sposoby do termomodulacji celowanej |
| GB201020236D0 (en) | 2010-11-30 | 2011-01-12 | Convatec Technologies Inc | A composition for detecting biofilms on viable tissues |
| CN104152530B (zh) | 2010-12-24 | 2017-09-19 | 爱科来株式会社 | 癌细胞的检测方法 |
| KR101308652B1 (ko) * | 2011-05-19 | 2013-09-13 | 제너럴바이오(주) | Ｍａｌ을 이용한 여드름 치료 조성물 |
| EP2779956A1 (en) | 2011-10-14 | 2014-09-24 | Photocure ASA | Stent |
| US20140276107A1 (en) | 2011-10-14 | 2014-09-18 | Photocure Asa | Photodynamic diagnosis |
| WO2013092505A1 (en) | 2011-12-19 | 2013-06-27 | Photocure Asa | Irradiation apparatus |
| WO2013092936A2 (en) * | 2011-12-20 | 2013-06-27 | Galderma Research & Development | Use of 5-aminolevulinic acid and esters, in combination with a vitamin d derivative or analog in photochemotherapy, and their uses in treating acne |
| CA2881439C (en) * | 2012-08-10 | 2017-08-29 | Dusa Pharmaceuticals, Inc. | Method for the treatment of acne |
| US20140067024A1 (en) | 2012-08-30 | 2014-03-06 | Photocure Asa | Dual panel photodynamic therapy lamp |
| EP2906286B1 (en) | 2012-10-11 | 2017-06-14 | Nanocomposix, Inc. | Silver nanoplate compositions and methods |
| JP2016507663A (ja) | 2012-12-20 | 2016-03-10 | コンバテック・テクノロジーズ・インコーポレイテッドＣｏｎｖａｔｅｃ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ | 化学修飾セルロース系繊維の加工 |
| KR101623553B1 (ko) * | 2013-07-23 | 2016-05-23 | 동성제약주식회사 | 여드름 치료, 예방 또는 개선에 유효한 클로린 e6 |
| BR112016014073A2 (pt) | 2013-12-20 | 2017-08-08 | Galderma Res & Dev | Tratamento fotodinâmico de pulso de pele fotodanificada |
| CA2935865A1 (en) | 2014-01-10 | 2015-07-16 | Sebacia, Inc. | Treatment intervals for use of compositions comprising energy absorbing materials for dermatological applications |
| US9956426B2 (en) | 2015-02-26 | 2018-05-01 | Amol Punjabi | Upconverting nanoparticles |
| US20160287615A1 (en) * | 2015-04-03 | 2016-10-06 | BioPharmX, Inc. | Novel encapsulation of fluorescent, photo-sensitive, or oxygen-sensitive active ingredient for topical application |
| US10603508B2 (en) | 2015-10-15 | 2020-03-31 | Dusa Pharmaceuticals, Inc. | Adjustable illuminators and methods for photodynamic therapy and diagnosis |
| EP3851161A1 (en) | 2015-10-15 | 2021-07-21 | DUSA Pharmaceuticals, Inc. | Adjustable illuminator for photodynamic therapy and diagnosis |
| CN106801037B (zh) * | 2017-01-06 | 2021-01-19 | 中国人民解放军南京军区福州总医院 | 体外痤疮炎症模型的建立方法及其应用 |
| US10632324B2 (en) | 2017-04-27 | 2020-04-28 | 9127-4910 Quebec Inc. | Method for the treatment of skin tissues |
| AU2018302103B2 (en) * | 2017-07-17 | 2024-03-07 | Sun Pharmaceutical Industries, Inc. | Photodynamic therapy method for skin disorders |
| US10357567B1 (en) | 2018-01-12 | 2019-07-23 | Dusa Pharmaceuticals, Inc. | Methods for photodynamic therapy |
| KR102171200B1 (ko) * | 2018-11-20 | 2020-10-28 | 제너럴바이오(주) | 5-아미노레불린산 수화염화물과 그 유도체를 유효성분으로 함유하는 여드름성 피부염 개선 또는 그의 조성물 |
| KR102265592B1 (ko) * | 2020-10-29 | 2021-06-17 | 김진왕 | 5-아미노레불린산 수화염화물을 포함하는 조성물 |
| KR20250021825A (ko) | 2023-08-07 | 2025-02-14 | 주식회사 아스트로젠 | 5-아미노레불린산 유도체 및 이를 포함하는 약학 조성물 |
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| WO1996028412A1 (en) * | 1995-03-10 | 1996-09-19 | Photocure As | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy |
| RU2128506C1 (ru) * | 1993-12-30 | 1999-04-10 | Л'Ореаль | Композиция против угрей с одновременным лечением поверхностных и глубоких слоев кожи и ее применение |
| WO2002013788A1 (en) * | 2000-08-16 | 2002-02-21 | The General Hospital Corporation D/B/A Massachusetts General Hospital | Topical aminolevulinic acid-photodynamic therapy for acne vulgaris |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US5234940A (en) | 1989-07-28 | 1993-08-10 | Queen's University | Photochemotherapeutic method using 5-aminolevulinic acid and precursors thereof |
| US6710066B2 (en) * | 1989-07-28 | 2004-03-23 | Queen's University At Kingston | Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins |
| US5079262A (en) * | 1989-07-28 | 1992-01-07 | Queen's University At Kingston | Method of detection and treatment of malignant and non-malignant lesions utilizing 5-aminolevulinic acid |
| US5955490A (en) * | 1989-07-28 | 1999-09-21 | Queen's University At Kingston | Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins |
| US5422093A (en) * | 1989-07-28 | 1995-06-06 | Queen's University | Photochemotherapeutic method using 5-aminolevulinic acid and precursors thereof |
| US5713845A (en) * | 1991-10-29 | 1998-02-03 | Thermolase Corporation | Laser assisted drug delivery |
| EP0660712B1 (en) | 1992-09-21 | 2001-05-30 | Quadra Logic Technologies Inc. | Transcutaneous in vivo activation of photosensitive agents in blood |
| GB9700396D0 (en) * | 1997-01-10 | 1997-02-26 | Photocure As | Photochemotherapeutic compositions |
| JPH1112197A (ja) | 1997-06-18 | 1999-01-19 | Cosmo Sogo Kenkyusho:Kk | 悪性腫瘍診断剤及び治療剤 |
| US6183773B1 (en) * | 1999-01-04 | 2001-02-06 | The General Hospital Corporation | Targeting of sebaceous follicles as a treatment of sebaceous gland disorders |
| DE10003620A1 (de) * | 2000-01-28 | 2001-08-02 | Asat Ag Applied Science & Tech | 5-Aminolävulinsäure-Formulierung in nichtwässrigen Lösungsmitteln |
| GB0018528D0 (en) * | 2000-07-27 | 2000-09-13 | Photocure Asa | Compounds |
| GB0118251D0 (en) * | 2001-07-26 | 2001-09-19 | Photocure Asa | Method |
| WO2003039597A1 (en) * | 2001-11-09 | 2003-05-15 | Qlt Inc. | Compositions comprising a photosensitizer and a skin-penetration enhancer and their use in photodynamic treatment |
| US20040048842A1 (en) * | 2002-09-10 | 2004-03-11 | Mcmillan Kathleen | Method of treating skin disorders |
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| US20050209330A1 (en) * | 2004-03-22 | 2005-09-22 | Syneron Medical Ltd. | Method of treatment of skin |
| GB0406917D0 (en) | 2004-03-26 | 2004-04-28 | Photocure Asa | Compounds |
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- 2005-11-04 JP JP2007540703A patent/JP5134370B2/ja not_active Expired - Fee Related
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| RU2128506C1 (ru) * | 1993-12-30 | 1999-04-10 | Л'Ореаль | Композиция против угрей с одновременным лечением поверхностных и глубоких слоев кожи и ее применение |
| WO1996028412A1 (en) * | 1995-03-10 | 1996-09-19 | Photocure As | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy |
| WO2002013788A1 (en) * | 2000-08-16 | 2002-02-21 | The General Hospital Corporation D/B/A Massachusetts General Hospital | Topical aminolevulinic acid-photodynamic therapy for acne vulgaris |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2635563C2 (ru) * | 2012-08-03 | 2017-11-14 | ФотоКьюэр АСА | Соединения |
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| US20130066256A1 (en) | 2013-03-14 |
| CN101056626A (zh) | 2007-10-17 |
| US20080188558A1 (en) | 2008-08-07 |
| RU2007115601A (ru) | 2008-12-20 |
| ATE469674T1 (de) | 2010-06-15 |
| CA2586195C (en) | 2013-12-31 |
| EP1814534A1 (en) | 2007-08-08 |
| AU2005303565A1 (en) | 2006-05-18 |
| ES2344986T3 (es) | 2010-09-13 |
| JP2008519812A (ja) | 2008-06-12 |
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| PL1814534T3 (pl) | 2010-11-30 |
| EP1814534B1 (en) | 2010-06-02 |
| SI1814534T1 (sl) | 2010-09-30 |
| PT1814534E (pt) | 2010-06-15 |
| CN101056626B (zh) | 2011-12-14 |
| AU2005303565B2 (en) | 2011-04-14 |
| GB0424833D0 (en) | 2004-12-15 |
| WO2006051269A1 (en) | 2006-05-18 |
| US8546447B2 (en) | 2013-10-01 |
| CA2586195A1 (en) | 2006-05-18 |
| DK1814534T3 (da) | 2010-09-20 |
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