CN101056626B - 利用5-氨基乙酰丙酸衍生物治疗痤疮 - Google Patents

利用5-氨基乙酰丙酸衍生物治疗痤疮 Download PDF

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Publication number
CN101056626B
CN101056626B CN2005800384462A CN200580038446A CN101056626B CN 101056626 B CN101056626 B CN 101056626B CN 2005800384462 A CN2005800384462 A CN 2005800384462A CN 200580038446 A CN200580038446 A CN 200580038446A CN 101056626 B CN101056626 B CN 101056626B
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ester
ala
acne
photosensitizer
ala ester
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CN101056626A (zh
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阿斯莱克·戈戴尔
乔·克拉维内斯
希尔德·莫里斯
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Photocure ASA
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0616—Skin treatment other than tanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Semiconductor Lasers (AREA)
CN2005800384462A 2004-11-10 2005-11-04 利用5-氨基乙酰丙酸衍生物治疗痤疮 Expired - Fee Related CN101056626B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0424833.2 2004-11-10
GB0424833A GB0424833D0 (en) 2004-11-10 2004-11-10 Method
PCT/GB2005/004253 WO2006051269A1 (en) 2004-11-10 2005-11-04 Treatment of acne using derivatives of 5-aminolevulinic acid

Publications (2)

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CN101056626A CN101056626A (zh) 2007-10-17
CN101056626B true CN101056626B (zh) 2011-12-14

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US (2) US20080188558A1 (enExample)
EP (1) EP1814534B1 (enExample)
JP (1) JP5134370B2 (enExample)
CN (1) CN101056626B (enExample)
AT (1) ATE469674T1 (enExample)
AU (1) AU2005303565B2 (enExample)
CA (1) CA2586195C (enExample)
DE (1) DE602005021677D1 (enExample)
DK (1) DK1814534T3 (enExample)
ES (1) ES2344986T3 (enExample)
GB (1) GB0424833D0 (enExample)
PL (1) PL1814534T3 (enExample)
PT (1) PT1814534E (enExample)
RU (1) RU2385718C2 (enExample)
SI (1) SI1814534T1 (enExample)
WO (1) WO2006051269A1 (enExample)

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GB0823265D0 (en) * 2008-12-20 2009-01-28 Convatec Technologies Inc Antimicrobial Composition
GB0823472D0 (en) 2008-12-23 2009-01-28 Photocure Asa Product
GB0900461D0 (en) 2009-01-12 2009-02-11 Photocure Asa Photodynamic therapy device
CN102458388B (zh) 2009-06-11 2016-09-28 光治疗Asa公司 半固体组合物及药物制品
JP2013521251A (ja) 2010-03-01 2013-06-10 フォトキュア エイエスエイ 美容組成物
EP2585111A1 (en) 2010-06-23 2013-05-01 Photocure ASA Hyperosmotic preparations comprising 5 -amino levulinic acid or derivative as photosensitizing agent
BR112013000613A2 (pt) 2010-07-09 2016-06-28 Photocure Asa composições secas e dispositivos que contêm tais composições secas
US9572880B2 (en) 2010-08-27 2017-02-21 Sienna Biopharmaceuticals, Inc. Ultrasound delivery of nanoparticles
PL3222266T3 (pl) 2010-08-27 2018-10-31 Sienna Biopharmaceuticals, Inc. Kompozycje i sposoby do termomodulacji celowanej
GB201020236D0 (en) 2010-11-30 2011-01-12 Convatec Technologies Inc A composition for detecting biofilms on viable tissues
CN104152530B (zh) 2010-12-24 2017-09-19 爱科来株式会社 癌细胞的检测方法
KR101308652B1 (ko) * 2011-05-19 2013-09-13 제너럴바이오(주) Ｍａｌ을 이용한 여드름 치료 조성물
EP2779956A1 (en) 2011-10-14 2014-09-24 Photocure ASA Stent
US20140276107A1 (en) 2011-10-14 2014-09-18 Photocure Asa Photodynamic diagnosis
WO2013092505A1 (en) 2011-12-19 2013-06-27 Photocure Asa Irradiation apparatus
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WO2014020164A1 (en) * 2012-08-03 2014-02-06 Photocure Asa Compounds
CA2881439C (en) * 2012-08-10 2017-08-29 Dusa Pharmaceuticals, Inc. Method for the treatment of acne
US20140067024A1 (en) 2012-08-30 2014-03-06 Photocure Asa Dual panel photodynamic therapy lamp
EP2906286B1 (en) 2012-10-11 2017-06-14 Nanocomposix, Inc. Silver nanoplate compositions and methods
JP2016507663A (ja) 2012-12-20 2016-03-10 コンバテック・テクノロジーズ・インコーポレイテッドＣｏｎｖａｔｅｃ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ 化学修飾セルロース系繊維の加工
KR101623553B1 (ko) * 2013-07-23 2016-05-23 동성제약주식회사 여드름 치료, 예방 또는 개선에 유효한 클로린 e6
BR112016014073A2 (pt) 2013-12-20 2017-08-08 Galderma Res & Dev Tratamento fotodinâmico de pulso de pele fotodanificada
CA2935865A1 (en) 2014-01-10 2015-07-16 Sebacia, Inc. Treatment intervals for use of compositions comprising energy absorbing materials for dermatological applications
US9956426B2 (en) 2015-02-26 2018-05-01 Amol Punjabi Upconverting nanoparticles
US20160287615A1 (en) * 2015-04-03 2016-10-06 BioPharmX, Inc. Novel encapsulation of fluorescent, photo-sensitive, or oxygen-sensitive active ingredient for topical application
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CN106801037B (zh) * 2017-01-06 2021-01-19 中国人民解放军南京军区福州总医院 体外痤疮炎症模型的建立方法及其应用
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KR102171200B1 (ko) * 2018-11-20 2020-10-28 제너럴바이오(주) 5-아미노레불린산 수화염화물과 그 유도체를 유효성분으로 함유하는 여드름성 피부염 개선 또는 그의 조성물
KR102265592B1 (ko) * 2020-10-29 2021-06-17 김진왕 5-아미노레불린산 수화염화물을 포함하는 조성물
KR20250021825A (ko) 2023-08-07 2025-02-14 주식회사 아스트로젠 5-아미노레불린산 유도체 및 이를 포함하는 약학 조성물

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WO2002013788A1 (en) * 2000-08-16 2002-02-21 The General Hospital Corporation D/B/A Massachusetts General Hospital Topical aminolevulinic acid-photodynamic therapy for acne vulgaris
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Also Published As

Publication number Publication date
JP5134370B2 (ja) 2013-01-30
US20130066256A1 (en) 2013-03-14
CN101056626A (zh) 2007-10-17
US20080188558A1 (en) 2008-08-07
RU2007115601A (ru) 2008-12-20
ATE469674T1 (de) 2010-06-15
CA2586195C (en) 2013-12-31
EP1814534A1 (en) 2007-08-08
AU2005303565A1 (en) 2006-05-18
ES2344986T3 (es) 2010-09-13
JP2008519812A (ja) 2008-06-12
DE602005021677D1 (de) 2010-07-15
PL1814534T3 (pl) 2010-11-30
EP1814534B1 (en) 2010-06-02
SI1814534T1 (sl) 2010-09-30
PT1814534E (pt) 2010-06-15
RU2385718C2 (ru) 2010-04-10
AU2005303565B2 (en) 2011-04-14
GB0424833D0 (en) 2004-12-15
WO2006051269A1 (en) 2006-05-18
US8546447B2 (en) 2013-10-01
CA2586195A1 (en) 2006-05-18
DK1814534T3 (da) 2010-09-20

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