RU2316324C2 - Фармацевтические композиции - Google Patents

Фармацевтические композиции Download PDF

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Publication number
RU2316324C2
RU2316324C2 RU2003109606/15A RU2003109606A RU2316324C2 RU 2316324 C2 RU2316324 C2 RU 2316324C2 RU 2003109606/15 A RU2003109606/15 A RU 2003109606/15A RU 2003109606 A RU2003109606 A RU 2003109606A RU 2316324 C2 RU2316324 C2 RU 2316324C2
Authority
RU
Russia
Prior art keywords
methyl
chloro
fluoroanilino
phenylacetic acid
composition
Prior art date
Application number
RU2003109606/15A
Other languages
English (en)
Russian (ru)
Other versions
RU2003109606A (ru
Inventor
Саймон Дейвид БЕЙТМАН (US)
Саймон Дейвид БЕЙТМАН
Альберто ДЖИМОНА (CH)
Альберто Джимона
Юрий ХОЛИНЕЙ (US)
Юрий ХОЛИНЕЙ
Яспер ХЮЛЬС (FR)
Яспер ХЮЛЬС
Сумедха ЯЯВАРДЕНЕ (US)
Сумедха ЯЯВАРДЕНЕ
Аргерис Джерри КАРАБЕЛАС (US)
Аргерис Джерри КАРАБЕЛАС
Маха Й. КХАЛЕД (US)
Маха Й. КХАЛЕД
Анеес Абдулкудар КАРНАЧИ (US)
Анеес Абдулкудар КАРНАЧИ
Аймэр Майрин НИК-ЛОЧЛАЙНН (IE)
Аймэр Майрин НИК-ЛОЧЛАЙНН
Ричард МАСЕРАТА (US)
Ричард МАСЕРАТА
Виктор СЛОАН (US)
Виктор СЛОАН
Original Assignee
Новартис Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Новартис Аг filed Critical Новартис Аг
Publication of RU2003109606A publication Critical patent/RU2003109606A/ru
Application granted granted Critical
Publication of RU2316324C2 publication Critical patent/RU2316324C2/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2003109606/15A 2000-09-11 2001-09-10 Фармацевтические композиции RU2316324C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US23165500P 2000-09-11 2000-09-11
US60/231,655 2000-09-11
US23226100P 2000-09-14 2000-09-14
US60/232,261 2000-09-14

Publications (2)

Publication Number Publication Date
RU2003109606A RU2003109606A (ru) 2004-08-27
RU2316324C2 true RU2316324C2 (ru) 2008-02-10

Family

ID=26925315

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2003109606/15A RU2316324C2 (ru) 2000-09-11 2001-09-10 Фармацевтические композиции

Country Status (28)

Country Link
US (2) US20020061932A1 (enExample)
EP (1) EP1331972B1 (enExample)
JP (2) JP2004527458A (enExample)
KR (1) KR20030036730A (enExample)
CN (1) CN100490797C (enExample)
AR (1) AR030630A1 (enExample)
AT (1) ATE366128T1 (enExample)
AU (2) AU2002213900C1 (enExample)
BR (1) BR0113809A (enExample)
CA (1) CA2416771C (enExample)
CY (1) CY1107729T1 (enExample)
CZ (1) CZ2003673A3 (enExample)
DE (1) DE60129238T2 (enExample)
DK (1) DK1331972T3 (enExample)
ES (1) ES2290181T3 (enExample)
HU (1) HUP0301128A3 (enExample)
IL (2) IL154238A0 (enExample)
MX (1) MXPA03002105A (enExample)
MY (1) MY126117A (enExample)
NO (1) NO20031095D0 (enExample)
NZ (1) NZ524785A (enExample)
PE (1) PE20020351A1 (enExample)
PL (1) PL359721A1 (enExample)
PT (1) PT1331972E (enExample)
RU (1) RU2316324C2 (enExample)
SI (1) SI1331972T1 (enExample)
SK (1) SK2902003A3 (enExample)
WO (1) WO2002020090A2 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR036312A1 (es) * 2001-08-31 2004-08-25 Novartis Ag Composicion farmaceutica
GB0201520D0 (en) * 2002-01-23 2002-03-13 Novartis Ag Pharmaceutical uses
CA2476744A1 (en) * 2002-03-07 2003-09-12 Novartis Ag Solid pharmaceutical compositions comprising lumiracoxib
US7220749B2 (en) 2002-06-11 2007-05-22 Nitromed, Inc. Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
AR042206A1 (es) 2002-11-26 2005-06-15 Novartis Ag Acidos fenilaceticos y derivados
TWI327913B (en) * 2003-03-12 2010-08-01 Novartis Ag Pharmaceutical composition comprising 5-methyl-2-(2'-chloro-6'-fluoroanilino)phenylacetic acid
US20050131028A1 (en) * 2003-09-11 2005-06-16 Pharmacia Corporation Methods and compositions for the extended duration treatment of pain, inflammation and inflammation-related disorders
RU2423979C2 (ru) * 2005-06-17 2011-07-20 АФТ Фармасьютикалз Лимитед Новая фармацевтическая композиция и ее применение в способе лечения пациентов с гиперемией и отеком слизистой оболочки верхних дыхательных путей
FR2898492B1 (fr) * 2006-03-15 2008-06-06 Pierre Fabre Medicament Sa Comprimes orodispersibles de domperidone
US20080014228A1 (en) * 2006-07-14 2008-01-17 Olivia Darmuzey Solid form
WO2008086537A2 (en) * 2007-01-11 2008-07-17 Analog Devices, Inc. Aluminum based bonding of semiconductor wafers
AU2009282901A1 (en) * 2008-08-22 2010-02-25 Novartis Ag Use of a COX-2 inhibitor for the treatment of a COX-2 dependent disorder in a patient not carrying HLA alleles associated with hepatotoxicity
US8227451B2 (en) 2008-11-12 2012-07-24 Auspex Pharmaceuticals Phenylacetic acid inhibitors of cyclooxygenase
CN103773596B (zh) * 2013-12-31 2016-05-18 上海复力生物医药科技有限公司 磷虾油的制备方法
KR102557900B1 (ko) 2016-09-07 2023-07-19 트러스티즈 오브 터프츠 칼리지 면역-dash 억제제와 pge2 길항제를 이용한 병행 요법
EP3687505A1 (en) 2017-09-26 2020-08-05 Tesaro Inc. Niraparib formulations

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2131423C1 (ru) * 1993-06-24 1999-06-10 Мерк Фросст Кэнада Инк. Дизамещенные фураноны, тиазолы и пентеноны в качестве ингибиторов циклооксигеназы, способ их получения, фармацевтическая композиция и способ лечения

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0701449T3 (da) * 1993-06-08 2003-11-10 Novartis Ag Fremgangsmåde til fremstilling af en oral fast dosisform indeholdende diclofenac
EP0910368A1 (en) * 1996-05-17 1999-04-28 Merck & Co., Inc. Compositions for a once a day treatment of cyclooxygenase-2 mediated diseases
CO4960662A1 (es) * 1997-08-28 2000-09-25 Novartis Ag Ciertos acidos 5-alquil-2-arilaminofenilaceticos y sus derivados
SA99191255B1 (ar) * 1998-11-30 2006-11-25 جي دي سيرل اند كو مركبات سيليكوكسيب celecoxib
AR036312A1 (es) * 2001-08-31 2004-08-25 Novartis Ag Composicion farmaceutica

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2131423C1 (ru) * 1993-06-24 1999-06-10 Мерк Фросст Кэнада Инк. Дизамещенные фураноны, тиазолы и пентеноны в качестве ингибиторов циклооксигеназы, способ их получения, фармацевтическая композиция и способ лечения

Also Published As

Publication number Publication date
SI1331972T1 (sl) 2007-12-31
CA2416771A1 (en) 2002-03-14
WO2002020090A9 (en) 2003-10-30
WO2002020090A3 (en) 2003-05-30
CY1107729T1 (el) 2013-04-18
CZ2003673A3 (cs) 2003-06-18
HUP0301128A3 (en) 2005-04-28
AU2002213900B2 (en) 2006-02-16
US20040186179A1 (en) 2004-09-23
PT1331972E (pt) 2007-10-16
CN1455691A (zh) 2003-11-12
CA2416771C (en) 2010-11-02
MXPA03002105A (es) 2003-06-19
US20020061932A1 (en) 2002-05-23
AR030630A1 (es) 2003-08-27
AU2002213900C1 (en) 2006-07-27
EP1331972B1 (en) 2007-07-04
DE60129238T2 (de) 2008-03-06
MY126117A (en) 2006-09-29
CN100490797C (zh) 2009-05-27
IL154238A (en) 2008-11-26
WO2002020090A2 (en) 2002-03-14
JP2011144194A (ja) 2011-07-28
DE60129238D1 (de) 2007-08-16
JP2004527458A (ja) 2004-09-09
NZ524785A (en) 2005-10-28
ES2290181T3 (es) 2008-02-16
AU1390002A (en) 2002-03-22
IL154238A0 (en) 2003-09-17
EP1331972A2 (en) 2003-08-06
DK1331972T3 (da) 2007-11-05
HUP0301128A2 (hu) 2003-10-28
KR20030036730A (ko) 2003-05-09
PE20020351A1 (es) 2002-06-14
PL359721A1 (en) 2004-09-06
NO20031095L (no) 2003-03-10
SK2902003A3 (en) 2003-10-07
NO20031095D0 (no) 2003-03-10
BR0113809A (pt) 2003-07-29
ATE366128T1 (de) 2007-07-15

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20120911