RU2312143C2 - ВЕКТОРЫ ДЛЯ ДОСТАВКИ МОЛЕКУЛ К ЭКСПРЕССИРУЮЩИМ CD11b КЛЕТКАМ - Google Patents

ВЕКТОРЫ ДЛЯ ДОСТАВКИ МОЛЕКУЛ К ЭКСПРЕССИРУЮЩИМ CD11b КЛЕТКАМ Download PDF

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RU2312143C2
RU2312143C2 RU2003110574/13A RU2003110574A RU2312143C2 RU 2312143 C2 RU2312143 C2 RU 2312143C2 RU 2003110574/13 A RU2003110574/13 A RU 2003110574/13A RU 2003110574 A RU2003110574 A RU 2003110574A RU 2312143 C2 RU2312143 C2 RU 2312143C2
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adenylcyclase
cells
antigen
molecule
cd11b
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RU2003110574/13A
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Russian (ru)
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RU2003110574A (ru
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Клод ЛЕКЛЕРК (FR)
Клод ЛЕКЛЕРК
Пьер ГЕРМОНПРЕ (FR)
Пьер ГЕРМОНПРЕ
Даниель ЛАДАН (FR)
Даниель ЛАДАН
Николь ГЮИЗО (FR)
Николь ГЮИЗО
Нади КЕЛЕФ (FR)
Надия КЕЛЕФ
Сесиль БОШ (FR)
Сесиль БОШ
Катрин ФАЙОЛЛЬ (FR)
Катрин ФАЙОЛЛЬ
ЭЛЬ-ИДРИССИ Мохаммед ЭЛЬ-АЗАМИ (FR)
ЭЛЬ-ИДРИССИ Мохаммед ЭЛЬ-АЗАМИ
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Энститю Пастеэр
Сантр Насьональ Де Ля Решерш Сьентифик
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    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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    • A61P35/00—Antineoplastic agents
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y406/00—Phosphorus-oxygen lyases (4.6)
    • C12Y406/01—Phosphorus-oxygen lyases (4.6.1)
    • C12Y406/01001—Aodenylate cyclase (4.6.1.1)
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K2039/10—Brucella; Bordetella, e.g. Bordetella pertussis; Not used, see subgroups
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    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2003110574/13A 2000-09-15 2001-09-14 ВЕКТОРЫ ДЛЯ ДОСТАВКИ МОЛЕКУЛ К ЭКСПРЕССИРУЮЩИМ CD11b КЛЕТКАМ RU2312143C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00402562.3 2000-09-15
EP00402562A EP1188446B1 (en) 2000-09-15 2000-09-15 Proteinaceous vectors for molecule delivery to CD11b expressing cells

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RU2003110574A RU2003110574A (ru) 2004-12-10
RU2312143C2 true RU2312143C2 (ru) 2007-12-10

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US (4) US20040001867A1 (enExample)
EP (2) EP1188446B1 (enExample)
JP (1) JP2004508065A (enExample)
KR (2) KR100879151B1 (enExample)
AT (2) ATE438409T1 (enExample)
AU (2) AU9385501A (enExample)
BR (1) BR0113915A (enExample)
CA (1) CA2422603A1 (enExample)
CZ (1) CZ2003726A3 (enExample)
DE (1) DE60042687D1 (enExample)
ES (1) ES2331348T3 (enExample)
HU (1) HUP0303126A3 (enExample)
PL (1) PL208864B1 (enExample)
PT (1) PT1188446E (enExample)
RU (1) RU2312143C2 (enExample)
WO (1) WO2002022169A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2585216C2 (ru) * 2009-03-23 2016-05-27 Институт Пастор Мутантные полипептиды суаа и производные полипептидов, подходящие для доставки иммуногенных молекул в клетку
RU2668795C2 (ru) * 2011-01-24 2018-10-02 Женкиотекс ПОЛИПЕПТИД, ПЕРЕНОСИМЫЙ CyaA (ВАРИАНТЫ), И ПРИМЕНЕНИЕ ДЛЯ ИНДУЦИРОВАНИЯ КАК ТЕРАПЕВТИЧЕСКОГО, ТАК И ПРОФИЛАКТИЧЕСКОГО ИММУННОГО ОТВЕТА

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PT1188446E (pt) 2000-09-15 2009-11-10 Pasteur Institut Vectores proteinácios para a distribuição da molécula a células que expressam cd11b
EP1489092A1 (en) * 2003-06-18 2004-12-22 Institut Pasteur Modified Bordetella adenylate cyclase comprising or lacking CD11b/CD18 interaction domain and uses thereof
JP2008500271A (ja) * 2003-10-14 2008-01-10 ザ・プロウボウスト・フェロウズ・アンド・スカラーズ・オブ・ザ・カレッジ・オブ・ザ・ホリー・アンド・アンデバイデッド・トリニティ・オブ・クイーン・エリザベス・ニア・ダブリン 免疫介在性疾患の治療および／または予防におけるアデニル酸シクラーゼ
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RU2517719C2 (ru) * 2008-05-29 2014-05-27 Трансжене Са Биомаркер для отбора пациентов и соответствующие способы
PL2233569T3 (pl) 2009-03-23 2015-02-27 Pasteur Institut Zmutowane polipeptydy cyaa i pochodne polipeptydu odpowiednie do dostarczania cząsteczek immunogennych do komórki
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EP2690172A1 (en) * 2012-07-23 2014-01-29 Genticel CYAA-based chimeric proteins comprising a heterologous polypeptide and their uses in the induction of immune responses
EP2975120A1 (en) 2014-07-17 2016-01-20 Institut Pasteur Monomeric and functional adenylate cyclase CyaA toxin
EP3323426A1 (en) 2016-11-17 2018-05-23 Ecole Nationale Vétérinaire de Toulouse Immunogenic and vaccine compositions for use against bordetella bronchiseptica infection
WO2018091613A1 (en) 2016-11-17 2018-05-24 Ecole Nationale Vétérinaire de Toulouse Immunogenic and vaccine compositions for use against bordetella bronchiseptica infection
EP3342421A1 (en) 2016-12-27 2018-07-04 Genticel Immunogenic composition comprising cyaa-derived polypeptide promoting a th1/th17-oriented immune response
WO2019177669A1 (en) * 2017-11-03 2019-09-19 Mackay Memorial Hospital Method for modulation of tumor associated myeloid cells and enhancing immune checkpoint blockade

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2585216C2 (ru) * 2009-03-23 2016-05-27 Институт Пастор Мутантные полипептиды суаа и производные полипептидов, подходящие для доставки иммуногенных молекул в клетку
RU2668795C2 (ru) * 2011-01-24 2018-10-02 Женкиотекс ПОЛИПЕПТИД, ПЕРЕНОСИМЫЙ CyaA (ВАРИАНТЫ), И ПРИМЕНЕНИЕ ДЛЯ ИНДУЦИРОВАНИЯ КАК ТЕРАПЕВТИЧЕСКОГО, ТАК И ПРОФИЛАКТИЧЕСКОГО ИММУННОГО ОТВЕТА

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HUP0303126A2 (hu) 2003-12-29
AU9385501A (en) 2002-03-26
PT1188446E (pt) 2009-11-10
WO2002022169A3 (en) 2002-11-21
JP2004508065A (ja) 2004-03-18
PL365743A1 (en) 2005-01-10
US20040001867A1 (en) 2004-01-01
DE60042687D1 (de) 2009-09-17
US10004794B2 (en) 2018-06-26
WO2002022169A2 (en) 2002-03-21
US9370564B2 (en) 2016-06-21
EP1317282B1 (en) 2011-08-03
EP1188446A1 (en) 2002-03-20
KR100953364B1 (ko) 2010-04-20
ES2331348T3 (es) 2009-12-30
US20120214206A1 (en) 2012-08-23
HUP0303126A3 (en) 2004-10-28
KR20080059684A (ko) 2008-06-30
CA2422603A1 (en) 2002-03-21
US20050238637A1 (en) 2005-10-27
BR0113915A (pt) 2003-07-01
AU2001293855B2 (en) 2007-04-26
EP1317282A2 (en) 2003-06-11
EP1188446B1 (en) 2009-08-05
PL208864B1 (pl) 2011-06-30
HK1057989A1 (en) 2004-04-30
ATE518880T1 (de) 2011-08-15
CZ2003726A3 (cs) 2003-09-17
ATE438409T1 (de) 2009-08-15
KR20030055265A (ko) 2003-07-02
KR100879151B1 (ko) 2009-01-19
US20160375119A1 (en) 2016-12-29

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