RU2311905C2 - 2-аминобензотиазолилмочевины в качестве модуляторов аденозина - Google Patents
2-аминобензотиазолилмочевины в качестве модуляторов аденозина Download PDFInfo
- Publication number
- RU2311905C2 RU2311905C2 RU2004121166/15A RU2004121166A RU2311905C2 RU 2311905 C2 RU2311905 C2 RU 2311905C2 RU 2004121166/15 A RU2004121166/15 A RU 2004121166/15A RU 2004121166 A RU2004121166 A RU 2004121166A RU 2311905 C2 RU2311905 C2 RU 2311905C2
- Authority
- RU
- Russia
- Prior art keywords
- methoxy
- morpholin
- ylbenzothiazol
- carboxylic acid
- amide
- Prior art date
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- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
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Applications Claiming Priority (2)
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| EP01129228.1 | 2001-12-10 | ||
| EP01129228 | 2001-12-10 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| RU2696278C2 (ru) * | 2012-07-18 | 2019-08-01 | Юниверсити Оф Нотр Дам Дю Лак | 5,5-гетероароматические противоинфекционные соединения |
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| US6727247B2 (en) * | 2001-12-10 | 2004-04-27 | Hoffman-La Roche Inc. | Substituted benzothiazole amide derivatives |
| JPWO2004002531A1 (ja) * | 2002-06-26 | 2005-10-27 | 小野薬品工業株式会社 | 血管の収縮または拡張による疾患治療剤 |
| EP1622569B1 (en) | 2003-04-24 | 2015-12-02 | Incyte Corporation | Aza spiro alkane derivatives as inhibitors of metallproteases |
| PT1636223E (pt) | 2003-05-19 | 2008-05-06 | F Hoffmann-La Roche Ag | Derivados de benzotiazole como ligandos de receptores da adenosina |
| RU2348629C2 (ru) * | 2003-05-30 | 2009-03-10 | Ф.Хоффманн-Ля Рош Аг | Производные бензотиазола и их применение при лечении заболеваний, связанных с аденозиновыми a2a-рецепторами |
| RU2006112847A (ru) | 2003-09-19 | 2007-11-10 | Ф. Хоффманн-Ля Рош Аг (Ch) | Производные тиазолопиридина в качестве лигандов аденозинового рецептора |
| EP1677791A4 (en) | 2003-10-31 | 2007-08-15 | Takeda Pharmaceutical | NITROGENIC CONDENSED HETEROCYCLIC COMPOUNDS |
| EP1720873B1 (en) | 2004-01-08 | 2011-02-23 | F. Hoffmann-La Roche AG | Diaza-spiropiperidine derivatives |
| KR100834179B1 (ko) * | 2004-05-24 | 2008-05-30 | 에프. 호프만-라 로슈 아게 | 4-하이드록시-4-메틸-피페리딘-1-카복실산(4-메톡시-7-모폴린-4-일-벤조티아졸-2-일)-아마이드 |
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| JP5202946B2 (ja) * | 2004-07-22 | 2013-06-05 | エフ．ホフマン−ラ ロシュ アーゲー | ベンゾチアゾール誘導体 |
| CN1989117B (zh) * | 2004-07-22 | 2011-01-19 | 弗·哈夫曼-拉罗切有限公司 | 取代的苯并噻唑 |
| NZ590148A (en) | 2004-12-30 | 2012-04-27 | Janssen Pharmaceutica Nv | Piperazinyl and piperidinyl ureas as modulators of fatty acid amide hydrolase |
| WO2006099972A1 (en) | 2005-03-23 | 2006-09-28 | F. Hoffmann-La Roche Ag | Acetylenyl-pyrazolo-pvrimidine derivatives as mglur2 antagonists |
| JP5048675B2 (ja) | 2005-09-27 | 2012-10-17 | エフ．ホフマン−ラ ロシュ アーゲー | ｍＧｌｕＲ２アンタゴニストとしてのオキサジアゾリルピラゾロ−ピリミジン類 |
| US8841334B2 (en) | 2006-05-31 | 2014-09-23 | Abbvie Inc. | Compounds as cannabinoid receptor ligands and uses thereof |
| WO2007140439A2 (en) * | 2006-05-31 | 2007-12-06 | Abbott Laboratories | Compounds as cannabinoid receptor ligands and uses thereof |
| US7910108B2 (en) * | 2006-06-05 | 2011-03-22 | Incyte Corporation | Sheddase inhibitors combined with CD30-binding immunotherapeutics for the treatment of CD30 positive diseases |
| CA2655310A1 (en) * | 2006-06-22 | 2008-05-29 | Cv Therapeutics, Inc. | Use of a2a adenosine receptor agonists in the treatment of ischemia |
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| TW200833328A (en) * | 2006-12-28 | 2008-08-16 | Actelion Pharmaceuticals Ltd | 2-aza-bicyclo[3.1.0]hexane derivatives |
| JP2010522760A (ja) | 2007-03-28 | 2010-07-08 | アボット・ラボラトリーズ | カンナビノイド受容体リガンドとしての１，３−チアゾール−２（３ｈ）−イリデン化合物 |
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| MX2009012374A (es) | 2007-05-18 | 2009-12-01 | Abbott Lab | Compuestos novedosos como ligandos del receptor de canabinoides. |
| AU2008263166A1 (en) * | 2007-05-25 | 2008-12-18 | Janssen Pharmaceutica N.V. | Heteroaryl-substituted urea modulators of fatty acid amide hydrolase |
| US8455520B2 (en) | 2007-07-17 | 2013-06-04 | Merck Sharp & Dohme Corp. | Soluble epoxide hydrolase inhibitors, compositions containing such compounds and methods of treatment |
| US9193713B2 (en) | 2007-10-12 | 2015-11-24 | Abbvie Inc. | Compounds as cannabinoid receptor ligands |
| US9226907B2 (en) | 2008-02-01 | 2016-01-05 | Abbvie Inc. | Extended release hydrocodone acetaminophen and related methods and uses thereof |
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| ES2283652T3 (es) | 2007-11-01 |
| US20040229893A1 (en) | 2004-11-18 |
| US20030149036A1 (en) | 2003-08-07 |
| EP1455792B1 (en) | 2007-04-18 |
| ATE359792T1 (de) | 2007-05-15 |
| EP1455792A1 (en) | 2004-09-15 |
| CA2469596A1 (en) | 2003-06-19 |
| DE60219682D1 (de) | 2007-05-31 |
| JP4245483B2 (ja) | 2009-03-25 |
| PA8559901A1 (es) | 2003-09-05 |
| AU2002356626A1 (en) | 2003-06-23 |
| US7019001B2 (en) | 2006-03-28 |
| US6727247B2 (en) | 2004-04-27 |
| RU2004121166A (ru) | 2005-05-10 |
| AU2002356626B2 (en) | 2007-11-29 |
| BR0214825A (pt) | 2004-09-14 |
| KR100659793B1 (ko) | 2006-12-19 |
| KR20040065576A (ko) | 2004-07-22 |
| DE60219682T2 (de) | 2008-01-17 |
| CN1602196A (zh) | 2005-03-30 |
| WO2003049741A1 (en) | 2003-06-19 |
| PL371063A1 (en) | 2005-06-13 |
| MXPA04005444A (es) | 2004-10-11 |
| TW200409628A (en) | 2004-06-16 |
| PE20030759A1 (es) | 2003-09-05 |
| JP2005516006A (ja) | 2005-06-02 |
| AR037731A1 (es) | 2004-12-01 |
| GT200200266A (es) | 2003-07-03 |
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