RU2287303C1 - Biologically active additive for improving functional state of gastrointestinal tract - Google Patents

Abstract

FIELD: phytotherapy.

SUBSTANCE: the present innovation deals with reconstructing normal body functions in complex therapy in case of obesity, particularly for normalizing functional state of gastrointestinal tract. The suggested food biologically active additive contains an active substance, caffeine, ascorbic acid, citric acid, sodium benzoate, a sweetening agent and water. As active substance one should apply concentrated aqueous extract of vegetable raw material mixture at the following ratio of components, weight%: concentrated aqueous extract of vegetable raw material mixture 2.8-3.2; caffeine 1.06-1.08; ascorbic acid 0.1-0.3; citric acid 0.1-0.3, sodium benzoate 0.06-0.1; a sweetening agent 0.02-0.06; water - the rest. Moreover, concentrated aqueous extract of vegetable raw material mixture should be prepared based upon the following constituents taken at equal quantities: origanum grass, dandelion root, prostrate knotweed grass, dogrose fruit, common bearberry leaf, mountain ash-tree fruit, hawthorn fruit and flowers. The innovation enables to normalize functional state of gastrointestinal tract and decrease appetite. Moreover, the additive suggested is of high tolerance value.

EFFECT: higher efficiency.

Description

The invention relates to the field of herbal medicine, namely to biologically active additives (BAA), and can be used to restore normal body functions in the treatment of obesity, in particular to normalize the functional state of the gastrointestinal tract.

It is known to use a remedy for healing the body, which contains oregano grass, dandelion root, knotweed (birdlance) grass, rose hips, rowan fruits, hawthorn, bearberry and several other components (RF Patent 2099410, 1997).

The disadvantage of this tool is the presence in its composition of scarce and expensive herbs and plants, which complicates the mass production of funds. In addition, the composition of the drug includes alcohol, which is not always beneficial for the treatment of certain diseases of the gastrointestinal tract.

It is known to use the fruits and flowers of hawthorn, oregano grass, dandelion root, grass of the mountaineer bird (knotweed) and rose hips as part of a fortifying agent (RF Patent 2171284, 2000).

A disadvantage of the known drug is the presence of alcohol in its composition. Not all people suffering from a disease of the gastrointestinal tract tolerate drugs made with the addition of alcohol.

The problem to which the claimed invention is directed is to create a means (biologically active food supplement), which, in addition to general strengthening and immunomodulating effects on the body, has a complex effect on the gastrointestinal tract, with good tolerance.

The technical result consists in normalizing the functional state of the gastrointestinal tract and reducing appetite.

The technical result is achieved due to the fact that in the tool for improving the functional state of the gastrointestinal tract containing the active substance, caffeine, ascorbic acid, citric acid, sodium benzoate, sweetener and water, a concentrated aqueous extract of a mixture of plant materials is used as the active substance, in the following ratio of components, wt.%:

concentrated aqueous extract of a mixture of plant materials - 2.8-3.2, caffeine - 1.06-1.08, ascorbic acid - 0.1-0.3, citric acid - 0.1-0.3, sodium benzoate - 0.06-0.1, sweetener 0.02-0.06, water - the rest, while a concentrated aqueous extract of a mixture of plant materials is prepared on the basis of equal quantities of oregano grass, dandelion root, bird of the mountaineer (knotweed), rose hips, bearberry leaf (bear ears), fruits of mountain ash, fruits and flowers of hawthorn.

The components that make up the tool are selected in the ratio that most effectively mobilizes the body's defenses. The proposed tool has a positive effect on carbohydrate and lipid metabolism, has a restorative effect on intestinal motility, has antispasmodic, choleretic, antimicrobial, analgesic and anti-inflammatory effects, which makes it preferred for use in diseases of the gastrointestinal tract.

The drug has been clinically tested. The study included 30 patients with metabolic syndrome (moderate arterial hypertension, obesity III-IV art., Type II diabetes mellitus or impaired carbohydrate tolerance) aged 30 to 48 years, 20 of them women and 10 men. The average weight of patients before treatment was 98.4 kg with an average height of 165.7 cm.

All patients were divided into two groups (15 people each), comparable in all studied parameters.

During clinical testing (3 weeks), all patients received a hypocaloric diet (1400 kcal / day) with two fasting days per week (600-700 kcal / day).

In this case, patients of the first group received only diet therapy, patients of the second group were additionally prescribed a tested dietary supplement with the following ratio of components, wt.%: Concentrated aqueous extract of a mixture of plant materials - 3.0, caffeine - 1.07, ascorbic acid - 0.1-0 , 3, citric acid - 0.2, sodium benzoate - 0.08, sweetener - 0.04, water - the rest. At the same time, to prepare a concentrated aqueous extract, plant material mixtures were taken in equal amounts of oregano, dandelion root, bird of the mountaineer (knotweed), rosehips, bearberry leaf (bear ears), fruits of mountain ash, fruits and flowers of hawthorn.

The test supplement was prescribed in 5-8 doses 3 times a day under the tongue half an hour before a meal.

While taking the proposed dietary supplement to food, none of the examined patients showed signs of intolerance to the drug. On the contrary, patients noted a pleasant sweet-grassy taste of the spray with a 10-minute “aftertaste”. No dyspeptic symptoms were detected.

In 85% of patients suffering from constipation, the function of the gastrointestinal tract improved, which was manifested by the appearance of regular (daily) stool.

Most patients receiving dietary supplements noted the appearance of an anorectic effect at the end of the first week of dietary supplement intake, which was expressed both in a decrease in the desire to eat and in a decrease in the intake of food consumed. This effect increased with further administration of the drug.

In the group of patients who received only diet therapy, at the end of the first week, stool normalization and loss of appetite were not observed.

The average weight of patients after treatment was 94.5 kg, which is 3.9 kg less than the average weight of patients before treatment. Moreover, the decrease occurred mainly due to patients taking dietary supplements.

In addition, in patients taking dietary supplements, there was a decrease in glycemia, normalization of lipid metabolism and a decrease in blood pressure.

Thus, the results of clinical trials indicate good tolerance, mild anorectic effect and hypotensive effect of the proposed tool (dietary supplement for food). The proposed dietary supplement has a positive effect on carbohydrate and lipid metabolism and can be successfully used not only as an independent tool for normalizing the functional state of the gastrointestinal tract, but also in complex therapy along with other drugs, for example, in the treatment of obesity.

Claims (1)

A dietary supplement to improve the functional state of the gastrointestinal tract, characterized in that it contains an active substance, caffeine, ascorbic acid, citric acid, sodium benzoate, a sweetener and water, and a concentrated aqueous extract of a mixture of plant materials is used as the active substance. in the following ratio of components, wt.%: Concentrated water herbal extract 2.8-3.2 Caffeine 1.06-1.08 Vitamin C 0.1-0.3 Lemon acid 0.1-0.3 Sodium benzoate 0.06-0.1 Sweetener 0.02-0.06 Water Rest at the same time, a concentrated aqueous extract of a mixture of plant materials is prepared on the basis of equal amounts of oregano, dandelion root, perennial grass, rose hips, bearberry leaf, common rowan fruits, hawthorn fruits and flowers.