KR100376305B1 - Healthy food composition for protecting hepatic - Google Patents

Abstract

The present invention relates to a health food composition for liver protection, 8% by weight of phosphorus mugwort, 6% by weight of eggplant, 6% by weight of ganoderma lucidum, 4% by weight of lioness, 4% by weight of dead sandfish, 4% by weight of dalgi, 4% by weight of aloe, Bokbunja 4 Weight%, Cheongung 4%, Cinnamon 4%, Wolfberry 4%, Baekchul 4%, Cornus 4%, Wagyu 4%, Plum 4%, Ogalpi 4%, Vinegar 4%, Baekbongryeong It is composed of 4% by weight, 4% by weight of sewage, 4% by weight of effervescent vinegar, 4% by weight of dandelion, and 8% of honey.

Description

Healthy food composition for protecting hepatic

The present invention relates to a health food composition for liver protection. More specifically, Injin mugwort, situation, manor, mountain lion, lioness (origin), coriander, aloe, bokbunja, celestial, cinnamon, gojija, baekryu, cornus, gugyang, plum, ogalpi, vines, baekbongryeong, seoho, eoseongcho, It relates to a health food composition that is excellent in palatability by producing a mixture of dandelion and effective in protecting the liver.

The liver is one of the most important organs of the body in food metabolism. Soy makes up 2.5 to 3% of the body weight and is the largest organ in the body. The liver weight of adults is about 1 to 1.5 kg. It is located in the right upper abdomen below the diaphragm and is divided into left and right lobes by a sickle-shaped ligament.

In living organisms, the liver mainly has three functions listed below. That is, as a first function, the liver acts as a digestive gland and secretes 500-1000 cc of bile per day to help digest and absorb fat in the small intestine. In addition, as a second function, the liver is involved in chemical alteration, storage and utilization, that is, intermediate metabolism in the body of various nutrients. In addition, as a third function, the liver has a detoxification effect, and detoxification treatment such as oxidation, reduction, agglomeration, etc. is applied to harmful substances in the body, for example, poisons and toxic substances made in the body, or mixed with bile for disposal. Send it to the kidneys to excrete it in urine.

About 80% of the liver's blood flow is the portal to the nutrients absorbed by the intestine, and the remaining 20% is the hepatic artery that carries oxygen and nutrients to the liver. Therefore, in liver cirrhosis, when blood circulation of the liver is inhibited, hypertension of the portal vein causes congestion of the esophagus, stomach, intestine, spleen, and various symptoms. The liver plays important roles such as bile secretion, detoxification and excretion of toxic substances in addition to the decomposition, synthesis and storage of nutrients carried through the portal.

Hepatic function has a large target action (cutting 4/5 of the liver, there is no risk of life) and strong regeneration. Hepatic blood flow is not always constant and has some reserve and plays a large role in the storage of blood or the regulation of blood volume. Nutrients transported to the liver in the context are ultimately degraded in the liver cells to become energy sources or resynthesized, stored in the liver or released into the blood.

Soy affects the absorption, metabolism and storage of nutrients, bile production, urea formation, osmotic pressure control, metabolite transport and blood coagulation. Monosaccharides (glucose, etc.) are synthesized as glycogen (glycogen) in hepatic cells, stored in the liver, and are degraded to glucose as needed to contribute to blood sugar control. It also calculates energy in the TCA cycle of mitochondria.

Fatty acids undergo β oxidation in the mitochondria of hepatic cells to become acetyl CoA. This acetyl CoA is oxidized in the TCA cycle and becomes an energy source that releases large amounts of ATP. Fatty acids are also synthesized in cholesterol and triglycerides and phospholipids are synthesized as fatty acids bind to glycerol. Fat stored in the liver (3-5%) is actively metabolized, and the action of anti-fatty liver factors (methionine, cholin, lecithin, etc.) does not always increase more than a certain amount of fat.

Amino acids are biosynthesized into proteins in hepatic cells, such as albumin, globulin, fibrinogen, prothrombin, lipoprotein, and stored in the liver (protein pool) or released into the blood. Fibrinogen and prothrombin are essential for blood coagulation, and lipoprotein is essential for the transport of fat in the blood. Amino acids in hepatic cells are metabolized by deamination or trans-amination of amine groups. Keto acids produced during deamination are oxidized in the Krebs cycle to provide energy. It is used for the production of ketone bodies or for the production of sugar. The ammonia produced by the deaminoation acts as a urea in the ornithin cycle and is excreted in the urine. Gluconeogenesis in the liver is when sugar is made from non-sugar substances such as amino acids, such as alanine, lactic acid and glycerol.

Hepatic cells store and activate various vitamins, especially A, D, B ₁ , B ₂ , folic acid, and B ₁₂ , and produce bile acids necessary for fat metabolism in the small intestine. Detoxication In addition, the fibrin is hydrophilic by binding to glucuronic acid in the liver, excreted into the intestine, and reduced by the intestinal bacteria to become urobilirubin. It is then oxidized to urobilins and excreted in the urine.

If liver abnormalities occur, metabolic disorders such as carbohydrate metabolism, lipid metabolism, protein and nitrogen metabolism, amino acid metabolism, protein metabolism, hepatic brain disease, vitamin metabolism, and malabsorption occur, and hepatic disease is caused by hepatitis, fatty liver and cirrhosis. Can get worse.

Hepatic disease refers to liver dysfunction due to metabolic dysfunction and biosynthetic dysfunction, for example, acute hepatitis caused by drugs or the like, or chronic hepatitis caused by chronic acute hepatitis, drinking fatty liver, or chronic hepatitis caused by these chronic diseases, It refers to the disease which shows various liver dysfunctions, such as viral infection caused by viral infection, or chronic infection which has become chronic, and cirrhosis of each intestinal remedy.

Similarly, as a method for treating hepatic disease, therapies for preserving hepatic function, for example, stable therapy, diet therapy and pharmacotherapy are known. Among these therapies, pharmacotherapy is specifically used in amino acids such as peptides such as aspartic acid, thioctic acid, methionine, thioproline, glycine and glutathione, soy extract extract, hepatic lysates, placental lysates, glucuronic acid derivatives and licorice. There is a therapy using extracted and purified glytilinine. Among these drugs, although glycitritin is known to be effective for improving hepatic function due to chronic hepatitis, the glycitritin has an administration problem that it is invalid for oral administration.

In addition, the pathogenesis of hepatic disease is not elucidated except by viral infection and addictive hepatitis, and the treatment of liver disease has been mainly used for stabilization therapy and diet therapy. In recent years, however, malotilate has been developed, which has the effect of inhibiting the progress of hepatic fibrosis by reactivating protein synthesis and RNA synthesis of hepatocytes. However, it is only recognized that such malolate is applied only to the treatment of cirrhosis.

In addition, Cyanidanool has been developed as an immune activator with unknown mechanism of action, and is said to be effective for the treatment of hepatitis B virus. However, in Italy and Portugal, the sale of cyanidanool is currently banned in Japan because a death accident occurred in a patient who administered cyanidinol. In addition, for these reasons, the development of drugs and foods effective in the treatment and prevention of a wide range of hepatic diseases, and excellent in stability is desired.

As a result of focusing on research on foods that can protect the liver, the inventors found natural herbs such as Injin mugwort, Situary, Ganoderma lucidum, Sansa, Hosa (origin), Dalbi, Aloe, Bokbunja, Cheongung, Cinnamon, Gugija, Baekchul, Cornus, Kwakhyang, The present invention was completed by discovering that the hepatoprotective effect can be obtained by ingesting a mixture of plum, ogalpi, vine, baekbongnyeong, eoseongcho, and dandelion.

Accordingly, an object of the present invention is to provide a health food composition excellent in hepatoprotective effect.

The object of the present invention is the natural medicinal herbs 8% by weight, situation 6% by weight, Ganoderma 6% by weight, hawthorn 4% by weight, 4% by weight of starfish, 4% by weight of arachnids, 4% by weight of aloe, 4% by weight of bokbunja, Cheongung 4%, Cinnamon 4%, Wolfberry 4%, Baekchul 4%, Cornus 4%, Wagyu 4%, Plum 4%, Ogalpi 4%, Vinegar 4%, Baekbongryeong 4% , 4% by weight of sewage, 4% by weight of eoseongcho, 4% by weight of dandelion, 8% of honey to prepare a health food composition for the protection of the liver, animal experiments were carried out using the composition to achieve the liver protection effect.

Hereinafter, the specific configuration and effects of the present invention will be described with reference to examples, but the selection of food types and the change in composition ratio may deteriorate the effects of health foods and intentionally and intentionally change the scope of rights among those skilled in the art. Of course, such a change in numerical range is within the scope of the present invention.

According to a preferred embodiment of the present invention, 8% by weight of phosphorus mugwort, 6% by weight of velvet, 6% by weight of ganoderma lucidum, 4% by weight of lioness, 4% by weight of starfish, 4% by weight of arachnids, 4% by weight of aloe, 4% by weight of bokbunja, Cheongung 4%, Cinnamon 4%, Wolfberry 4%, Baekchul 4%, Cornus 4%, Wagyu 4%, Plum 4%, Ogalpi 4%, Vinegar 4%, Baekbongryeong 4% , 4% by weight of sewage, 4% by weight of eoseongcho, 4% by weight of dandelion, 8% of honey finely pulverized into a powder and then mixed to process the powder in the form of a ring.

Artemisia Messerschmidtiana Besser, also called raw mugwort, is a perennial plant from 1 to 1.5m high. The outposts of Injin mugwort include essential oils (pinene, terpinene, limonene, terpineol, cineol), aromatic oxycarboxylic acids (chlorogenic acid, caffeic acid, perolanic acid), flavonoids and oxycoumarins (scopolline, scopoline). Nowadays, Umbelliferon has also been isolated. In motion therapy, it is used for inflammatory medicine, fever lowering medicine, urinary medicine, and fever tingling medicine, such as fever jaundice, hepatitis and cholecystitis.

The hawthorn is diuretic because it contains quercetin and oleanoic acid like quince, and it contains vitamin B, C, carotene and chlorogenic acid, which is effective for postpartum abdominal pain, hangover, dryness, indigestion and chronic diarrhea. It also helps regulate gastrointestinal activity and treat indigestion.

Hosa is also called perilla, a perennial herb of the genusaceae. The roots are thick and long, and several stalks come out at the ends and grow to around 30 cm and have almost no hair. Flowers bloom in July-August, purple, sparsely hanging in inflorescences. Calyxes are 5, 2 at the rear and 2 at the bottom, linear and 2 like petals. Petals are open at the top, attached at the bottom, and chopped like a brush. The fruit is flat and split into two. In oriental medicine, the root is called Wonji, and it is used as expectorant, tonic and gangjeong.

It is a perennial flower attached to the chickweed grass family and is also called chickweed grass. It is 15-50cm tall and can eat young leaves and stems with medicine.

Aloe sp. Contains 16-20% of Aloe C ₂₀ H ₁₈ O ₉ , Aloe-Emodine, Nataloine, Labarberon, 12% Resin, and is a bitter tonic, digestive and appetite, and diarrhea. In motion therapy, children's markers, constipation 1 ~ 2g is used a day.

Bokbun is a fruit of Rubus sachalinensis Lev., Organic acid including 2.2% lemon acid, salinic acid, capronic acid, formic acid and salts thereof, large amount of pectin, carotene (0.3mg%), vitamin B group, glucose 4.3%, fructose 8%, sucrose 6.5%, tannins 0.3%, thianidine chloride C ₂₇ H ₃₁ O ₆ , acetoin C ₄ H ₈ O ₂ , β-yonone, benzaldehyde. Bokbunja decoction is a fever lowering effect and cardiac diuresis in animal experiments. In motion therapy, Bokbunja antipyretic fever is used as cold, febrile disease, pneumonia, cough, and gangjeong tonic.

Cheongung is the root of Sangusti (Ligusticum jeholense Kitag.) And contains essential oils, coumarins, and soothing functions.

Cinnamon [Zanthoxylum piperitum (L.) DC. ] The fruit peel to the fruit peel and fruit of the Japanese pepper tree, the refinery there is 2-4%, the main component is dipentene _{C 10 H 16 (54%)} , blackbird Trojan nelral C ₁₀ H ₁₈ (8%), l-β-phellandrene C ₁₀ H ₁₆ (54%), geraniol and chitronellol. In addition, the fruit contains 5-8% of Sansol Ⅰ and Ⅱ as a spicy ingredient, which has local paralysis effect and the stronger the fruit, the more bactericidal activity against various pathogenic bacteria. In motion therapy, it is an aromatic dry placebo inflammatory drug used for gastroenteritis, gastric dilatation and stomach and sewage. It is also used as a urinary medicine, topical excitement medicine, insect repellent medicine.

Phellinus linteus is a white fungus belonging to the genus Phellinus of the family Hymenochaetaceae, and has a very strong tumor inhibition rate of 96.7% in fruiting body extracts. Regulation is known.

Gojija (Lycium chinense Miller) is a fruit of Goji berries, vitamins of 0.1%, carotenoids zeaxanthin, and recently identified the biologically active scoplatin. In addition, carotenoids and sterins were also isolated, which are pisalien and β-cytosterin. Gojija has the effect of lowering blood pressure and reducing the amount of cholesterol in the blood is used to prevent and treat atherosclerosis. In motion therapy, the fruit is used as a supplement to lower back pain, helplessness, dizziness, head pain, and oxal, and it is said that if you eat it for a long time, it will strengthen your bones, lighten your body, darken your gray hair, brighten your eyes, and live long without cold and heat. .

It is also known as the root or root stem of Atractylodes japonica (Koidz.) Kitag, a perennial herb, about 80 m high. Casseroles in spring or autumn are washed with water to make fine roots and dried in the sun. Root stem contains about 1.5% of essential oils, carotene, inulin, gum and alkaloids. Essential oils have sedation, central nerve palsy, blood pressure lowering, and urinary action, and they are widely used for dyspepsia as a directional placebo. In motion therapy, extra water in the body is released out of the body. It is a very important medicine that is formulated in the synergistic prescription as urinary and sweating medicines in the digestive tract or subcutaneous tissues. It also stops diarrhea and vomiting. It is used for diabetes, pulmonary tuberculosis and cough, rheumatism, gout, febrile disease, cold, liver disease, spleen disease, and malignant tumors.

Cornus (Macrocarpium officinale Sieb. Et Zucc.) Is a fruit bark of the hawthorn tree, which includes crystalline organic acids, glutinous assets, malic acid, and grape acids, and the fruit shells include iridonide glycosides such as moronisides and loganins. In motion therapy, nourishment tonic and astringents are used to see the kidneys, and when sweating frequently and urine comes out little by little, it is used when the back pain and the moon are uneven.

Called Agastache rugosa (Fisher et Meyer) O. Kuntze, the perennial herb is 1-1.5m high, essential oil is about 0.3% for outpost, 0.2-2.3% for leaves, 5% for flowers, 0.1% on the stem. The main components of essential oils are methylcarbigol, anisealdehyde, anetol, d-limonene, sesquiterpene, α-pinene, β-pinene, α-limonene, oxanone, P-chimol, linalol, and acachettin as flavonoid , Tilianin, linarin, and agathacoside were isolated. In motion therapy, it is used for cold, head pain and vomiting diarrhea when eating or eating heat with dry stomach medicine, old wind medicine, digestive medicine, heat lowering medicine. It is also rarely used as a drug for the treatment of cortex and tumors, and is an important medicine especially for the spleen and gastrointestinal diseases.

Plums rule the liver and the phlegm, strengthen the cells, make the blood normal, reduce heat and stop limb pain. It also controls the heat of the intestines, controls thirst, eliminates cold and stops diarrhea. And menstrual irregularity, inflammation, stool irritation, stool bleeding, pissing, palsy, is used in the game.

Ogalpi is a bark of the Acanthopanax sessiliflorum Seeman, which contains glycosides, acanthosides, tanyls, essential oils, vitamins A and C, and oil. Ogalpi has polysaccharides that are soluble in water, which helps to loosen and absorb the ingredients in herbs. In motion therapy, it is used to strengthen the body, torture, roughness, pain and weakness, arthritis, neuropathy, anorexia, individual pain, cold, back pain, pregnancy pain, and stomach.

The vine is a yearly vine plant of the chickweed family and grows in damp areas at the foot of the mountain. Stems are clustered, branched, light, about 80 cm long, leaves alternate, long petioles, heart-shaped, with sharp tips and flat edges. In July-August, 2 ~ 3 white flowers bloom at the end of branches and stems, 5 ~ 6 mm in diameter. Calyxes have 1 to 3 veins, about 4 mm long, with curly hairs on the operating table, and fruit has three ridges with oak, oval, 8-11 mm long, without hairs. Seeds are contained in 2-6 pieces, and the outer surface has small bumps. Young stems and leaves are edible.

The content of Poria cocos (Schw.) Wolf. Consists of about 94% of the polysaccharide pakiman, triterpenic acid, sugars, minerals, and ergosterol. When not, swelling, bite, eat when things go down and have no appetite, gastric constant, heart swelling, sleep can not be used. It is also used for muscle hepatic cramps and dizziness.

Sewage is the root of a red gourd (polygonum multiflorum Thunb.) Containing 1.8% oxymethylanthraquinone derivatives, about 45% horses, about 3% oil, 3.7% lecithin, and about 26% loosening material. In motion therapy, sewage is used for skin diseases such as postpartum and senile constipation, scabies and eczema. Tonic, blood is said to be stronger than Chihwang Root or Astronomical Dong.

Hottuynia cordata Thunb. Is a perennial herb, also known as weak wheat, 15-30 cm high. Outpost is an inflammatory drug and diuretic poisoning agent, which is used for gonorrhea, urethritis, cystitis, uterus, pneumonia, bronchitis, bite, athlete's foot, browning, and swelling.

Ganoderma lucidum is a fungus that is also called Bulchocho. It occurs in the roots of hardwoods in summer and also sprouts on the ground. In oriental medicine, it is effective in tonic, Jinhae, and small sarcoma. Ganoderma lucidum is covered with a hard skin and has a glossy appearance like varnish. It is used as an herbal medicine in Japan as a mushroom in Japan and as a territory in China.

Dandelion (Taraxacum Platycarpum H.dahlsi.) Is a medicine for treating hepatobiliary diseases, peptic digestion, and rice flavoring. In motion therapy, it is a placebo, urinary medicine, puff medicine, indigestion, gastritis, stomach pain, lactation, stiffness and squeezing of the urine, which is used to stop colds, sore throat, and eye disease.

The present invention is not harmful to the human body as a food at all, we are always edible food raw materials that grow in the field of edible edible (edible) raw materials, the situation, ganoderma lucidum, hawthorn, lions (origin), coriander, aloe, bokbunja Finely pulverized, Cheongung, Cinnamon, Wolfberry, Baekchul, Cornus, Kwakhyang, Plum, Ogalpi, Vinegar, Baekbongryeong, Shouo, Echochocho, and Dandelion, and then dried and mixed with powder. It is useful because some of them are involved in metabolic action such as liver protection.

Ingredients contained in the health food composition of the present invention are all used as herbal medicines, food ingredients and foods, it is excellent in safety to the human body when taking or ingesting.

On the other hand, the operation according to the configuration of the present invention will be described. If there is a disease, the face is yellowish, urine is not discharged, edema occurs, and in order to protect the liver, an organ that does not like moisture and heat, phosphorus mugwort is added as a main medicine. It removes moisture and removes jaundice to help the liver. The situation and ganoderma play a role to strengthen and bolster blood vessels. It acts to release, Sansa, Baekchul, Gwakhyang, Baekbokyeong serves to help the digestion of the drug, Bokbunja, plum, and cornus milk to prevent the drug is not absorbed and excreted outside the body while tonic, Aloe It has the effect of clearing, celestial, cinnamon, and porridge help to circulate Qi, and goji and sewage help to produce blood. The blood acts to strengthen the musculature while removing moisture, and the cochlea and vines assist the action of fish and dandelion, and the honey is used as a base in the manufacture of pills. Is powdered according to a conventional method, but may be extracted with hot water or an organic solvent, put in a carrier, dried and encapsulated, or may be formulated in the form of other tablets, granules, powders, beverages, porridge and the like.

Examples of the health food composition for protecting the liver of the present invention are as follows. Meanwhile, honey added in Example 1 is known in the art as an ingredient added to prepare a medicinal herb in a cyclic form.

Example 1 Composition for Hepatoprotection in Ring Form (Unit: 100% by weight)

Injin mugwort 8% by weight

Situation 6% by weight

Ganoderma lucidum 6 wt%

Sun Lion 4% by weight

Dead lion (raw) 4% by weight

4% by weight

Aloe 4 wt%

Bokbunja 4% by weight

Cheongung 4% by weight

Cinnamon 4 wt%

Wolfberry 4 wt%

4 wt%

Cornus 4% by weight

Outline 4% by weight

4% by weight of plum

Ogalpi 4 wt%

4% by weight of vines

Baekbong-ryeong 4 wt%

Sewage 4 wt%

Eoseongcho 4% by weight

Dandelion 4% by weight honey 8%

Hereinafter, an animal experiment for measuring the hepatoprotective effect according to an embodiment of the present invention and the results are presented.

Experimental Example 1 Effect of the Hepatoprotective Health Food Composition of the Invention on Acute Hepatic Injury by Carbon Tetrachloride

As experimental animals, Sprague-Dawley rats with a body weight of about 200 g were allowed to adapt to the animal breeding room where constant temperature and humidity were maintained for at least one week. It was used for the experiment.

The 50 rats selected as above were divided into 5 groups of 10 rats each, and were administered at different doses of the hepatoprotective health food composition of the present invention. Carbon tetrachloride (CCl4) and corn oil are mixed at 1: 4 (v / v%) and orally administered by 0.2 mL per 100 g of body weight, and saline is administered to the normal control group (A) and carbon tetrachloride control group (B). In the experimental group, the health food composition of the present invention was suspended in 0.9% saline solution and injected intravenously at 1 mg / kg / day (C), 20 mg / kg / day (D) and 100 mg / kg / day (E), respectively. It was administered, the administration period is four days as shown in Table 1 below.

Dosing schedule Dosing schedule 1 day 2 days 3 days 4th 6pm 9th 4pm A Saline Saline Saline Saline Corn oil B Saline Saline Saline Saline Carbon tetrachloride C Health Food Composition 1mg / ㎏ / day Health Food Composition 1mg / ㎏ / day Health Food Composition 1mg / ㎏ / day Health Food Composition 1mg / ㎏ / day Carbon tetrachloride D Health Food Composition 20mg / ㎏ / day Health Food Composition 20mg / ㎏ / day Health Food Composition 20mg / ㎏ / day Health Food Composition 20mg / ㎏ / day Carbon tetrachloride E Health food composition 100mg / ㎏ / day Health food composition 100mg / ㎏ / day Health food composition 100mg / ㎏ / day Health food composition 100mg / ㎏ / day Carbon tetrachloride [Note] 1. Saline: 0.9% 2. Carbon tetrachloride: 2.5 mL / kg / day 3. Carbon tetrachloride is orally administered in combination with corn oil 4. The health food composition of the present invention hepatoprotective and liver disease treatment is suspended orally administered in 0.9% saline

On day 5 after the drug was administered as described above, blood was collected from the heart under anesthesia after 12 hours of fasting, and the activity of serum enzymes was measured as shown in Table 2 below.

Activity Levels of Serum Enzymes S-AST and S-ALT S-AST S-ALT Numerical value (U / L) ratio Numerical value (U / L) ratio A 85 ± 5 - 46 ± 3 - B 4879 ± 652 100.0 1381 ± 386 100.0 C 2613 ± 989 53.6 564 ± 169 408 D 352 ± 52 7.2 115 ± 22 8.3 E 161 ± 27 3.2 67 ± 12 4.8

Experimental results showed that the hepatoprotective effect is remarkably improved as the dose of the present invention is increased.

Experimental Example 2: Comparison of the hepatoprotective effect of the present liver food health care composition and alpha tocopherol

In order to compare the hepatoprotective effect of the alpha-tocopherol known to have a hepatoprotective effect and the hepatoprotective health food composition of the present invention using the rat as in Experiment 1, the hepatoprotective health food composition of the present invention is 20 mg / kg / day Tocopherol was administered at a dose of 350 mg / kg / day, and blood of each experimental group was collected to compare S-AST and A-ALT.

Experimental results As shown in Table 3 it can be seen that the administration of the present invention, hepatoprotective health food composition showed a better hepatoprotective effect than tocopherol.

S-AST S-ALT Numerical value (U / L) ratio Numerical value (U / L) ratio Normal control 100 ± 4 4.1 38 ± 1 2.6 Carbon tetrachloride control group 2439 ± 148 100.0 1482 ± 44 100.0 Health food composition administration group of the present invention 1251 ± 117 50.9 276 ± 19 18.6 Experimental Example 3 Experimental Effect Test for Epilepsy and Poor Development (Human Clinical Trial) Yonsei Univ. To Lee Soo-yeon (Heo, Resident Registration No. 981002-2038010) 5 months in pediatrics, Sinchon Severance Hospital, medical school affiliated to the medical school did not have the effect of the soy sauce protective composition of the present invention prepared in Example 1 was suspended orally administered in 0.9% saline based on 100mg / kg every 30 minutes after 3 times a day As a result, after 7 days, the walking became stable and high fever (38.5 ℃) began to be resolved. After 3 months, epilepsy was treated and development progressed to normal.

According to the present invention as described in the above Examples and Experimental Examples, the above-described hepatoprotective health foods are used, and when used, there is an excellent effect of satisfying the user without side effects, and is very useful in the health food industry because it has an excellent effect on the protection of the liver. It is an invention.

Claims (1)

Injin mugwort 8% by weight, Situary 6% by weight, Ganoderma lucidum 6% by weight, Mountain Lion 4% by weight, Red Lion 4% by weight, Whaling Bee 4% by weight, Aloe 4% by weight, Bokbunja 4% by weight, Cheongung 4% by weight, Cinnamon 4% by weight , 4% by weight of Goji, 4% by weight of corn, 4% by weight of cornus oil, 4% by weight of plum, 4% by weight of plum, 4% by weight of vinegar, 4% by weight of Baekbyeongyeong, 4% by weight of Baekbyeong, 4% by weight of sewage Health food composition for liver protection, characterized in that consisting of%, dandelion 4% by weight, honey 8%.