RU2283115C2 - Новые вещества, связывающиеся с helicobacter pylori, и их применение - Google Patents

Новые вещества, связывающиеся с helicobacter pylori, и их применение Download PDF

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Publication number
RU2283115C2
RU2283115C2 RU2002118703/15A RU2002118703A RU2283115C2 RU 2283115 C2 RU2283115 C2 RU 2283115C2 RU 2002118703/15 A RU2002118703/15 A RU 2002118703/15A RU 2002118703 A RU2002118703 A RU 2002118703A RU 2283115 C2 RU2283115 C2 RU 2283115C2
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binding
helicobacter pylori
substance
glycosphingolipids
lactotetraosylceramide
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RU2002118703/15A
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Russian (ru)
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RU2002118703A (ru
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Карл-Андерс КАРЛССОН (SE)
Карл-Андерс КАРЛССОН
Ирене ЛЕОНАРДССОН (SE)
Ирене ЛЕОНАРДССОН
Сусанн ТЕНЕБЕРГ (SE)
Сусанн ТЕНЕБЕРГ
Йонас ОНГСТРЕМ (SE)
Йонас ОНГСТРЕМ
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
RU2002118703/15A 1999-12-15 2000-12-15 Новые вещества, связывающиеся с helicobacter pylori, и их применение RU2283115C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9904581-7 1999-12-15
SE9904581A SE9904581D0 (sv) 1999-12-15 1999-12-15 A novel helicobacter pylori-binding substance and use thereof

Publications (2)

Publication Number Publication Date
RU2002118703A RU2002118703A (ru) 2004-02-20
RU2283115C2 true RU2283115C2 (ru) 2006-09-10

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RU2002118703/15A RU2283115C2 (ru) 1999-12-15 2000-12-15 Новые вещества, связывающиеся с helicobacter pylori, и их применение

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Country Link
US (1) US20040086514A1 (https=)
EP (1) EP1237558A1 (https=)
JP (1) JP2003517015A (https=)
CN (1) CN100389773C (https=)
AU (1) AU783876B2 (https=)
CA (1) CA2392766A1 (https=)
CZ (1) CZ20021989A3 (https=)
EE (1) EE200200312A (https=)
HU (1) HUP0204243A3 (https=)
IL (1) IL150247A0 (https=)
NO (1) NO20022890L (https=)
NZ (1) NZ520111A (https=)
PL (1) PL356329A1 (https=)
RU (1) RU2283115C2 (https=)
SE (1) SE9904581D0 (https=)
SK (1) SK8152002A3 (https=)
WO (1) WO2001043751A1 (https=)
ZA (1) ZA200204251B (https=)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
RU2462476C2 (ru) * 2006-10-10 2012-09-27 Юниверсите Де Нант Применение моноклональных антител, специфичных к о-ацетилированной форме ганглиозида gd2, для лечения некоторых форм рака

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SE9904581D0 (sv) * 1999-12-15 1999-12-15 A & Science Invest Ab A novel helicobacter pylori-binding substance and use thereof
FI20010118L (fi) * 2001-01-19 2002-07-20 Carbion Oy Uudet helicobacter pylori reseptorit ja niiden käyttö
EP1411952B1 (en) * 2001-06-29 2009-04-22 Glykos Finland Oy Use of at least one glycoinhibitor substance against infectious diseases
FI20011403L (fi) * 2001-06-29 2002-12-30 Carbion Oy Menetelmä ja koostumukset vatsan sairauksien hoitoon
AU2003201619A1 (en) * 2002-01-18 2003-07-30 Biotie Therapies Corporation Novel binding epitopes for helicobacter pylori and use thereof
EP1332759B1 (en) * 2002-02-04 2005-09-28 Kyowa Hakko Kogyo Co., Ltd. Pharmaceutical and nutritional compositions containing a di- or oligosaccharide as insulin secretion promoter
DK1531832T3 (da) * 2002-06-28 2009-07-27 Glykos Finland Oy Terapeutiske sammensætninger til anvendelse ved profylakse eller behandling af diarré
FI20021989A0 (fi) * 2002-11-06 2002-11-06 Halina Miller-Podraza Korkean affiniteetin Helicobacter pylori-reseptorit ja niiden käyttö
WO2006094267A2 (en) * 2005-03-03 2006-09-08 Indiana University Research And Technology Corporation Permethylation of oligosaccharides
JP4677525B2 (ja) * 2005-08-23 2011-04-27 国立大学法人 長崎大学 ヘリコバクター・ピロリの空胞化毒素の検出試薬および検出方法
JP5014018B2 (ja) * 2006-10-18 2012-08-29 旭化成ケミカルズ株式会社 ピロリ菌の抑制剤または静菌剤
JP4811953B2 (ja) * 2007-01-12 2011-11-09 公益財団法人野口研究所 α−Ｎ−アセチルグルコサミニル結合単糖誘導体を含有するピロリ菌増殖抑制剤
EP2060257A1 (en) 2007-11-08 2009-05-20 Nestec S.A. Prevention and treatment of secondary infections following viral infection
GB0817908D0 (en) 2008-10-01 2008-11-05 Univ Ghent Blood group a/b/h determinant on type 1 core glycosphinglipids chain as recognition point for the fedf protein of f18-fimbriated enterotoxigenic
US20110237788A1 (en) * 2008-10-10 2011-09-29 The Noguchi Institute Helicobacter pylori bacterium proliferation inhibitor
EP2844301A2 (en) * 2012-05-04 2015-03-11 Ineb-instituto de Engenharia Biomédica Microspheres for treating helicobacter pylori infections

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WO1981003175A1 (en) * 1980-05-09 1981-11-12 H Leffler Carbohydrate derivatives for inhibiting bacterial adherence
RU95118394A (ru) * 1993-02-26 1998-01-10 Стаффан Нормарк Ян Использование гликозидов олигосахаридов в качестве ингибиторов адгезии бактерий
RU2124729C1 (ru) * 1993-03-31 1999-01-10 Смит Клайн Дайагностикс, Инк. Устройство для хроматографического анализа для обнаружения и/или определения аналита в образце (варианты)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2462476C2 (ru) * 2006-10-10 2012-09-27 Юниверсите Де Нант Применение моноклональных антител, специфичных к о-ацетилированной форме ганглиозида gd2, для лечения некоторых форм рака

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PL356329A1 (en) 2004-06-28
CZ20021989A3 (cs) 2002-10-16
IL150247A0 (en) 2002-12-01
JP2003517015A (ja) 2003-05-20
AU2418801A (en) 2001-06-25
RU2002118703A (ru) 2004-02-20
NO20022890L (no) 2002-08-15
US20040086514A1 (en) 2004-05-06
NO20022890D0 (no) 2002-06-17
EP1237558A1 (en) 2002-09-11
AU783876B2 (en) 2005-12-15
NZ520111A (en) 2004-08-27
CN100389773C (zh) 2008-05-28
ZA200204251B (en) 2003-05-28
SK8152002A3 (en) 2002-11-06
SE9904581D0 (sv) 1999-12-15
CN1411376A (zh) 2003-04-16
HUP0204243A3 (en) 2003-08-28
HUP0204243A2 (hu) 2003-03-28
CA2392766A1 (en) 2001-06-21
EE200200312A (et) 2003-06-16
WO2001043751A1 (en) 2001-06-21

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