RU2200041C2 - Method for treating patients for sclerosus multiplexus by means of laser radiation - Google Patents

Abstract

FIELD: medicine. SUBSTANCE: method involves carrying out transcutaneous irradiation of injured spinal cord segments projections from the back side with infrared radiation of 700-1000 nm and mean power of 20-150 mW in scanning mode during 10-120 min. Brain is irradiated through occipital and temporal foramens during 5-60 min per each foramen and axillary and inguinal lymph nodes are treatment during 1-10 min per each node. The mentioned sites are irradiated in sequentially during one session. The sessions are given daily with pauses made on holidays during 3-6 months. EFFECT: prevented disease progressive development; restored work of injured organs and systems.

Description

 The invention relates to laser medicine and is intended for the treatment of patients with multiple sclerosis (PC) by irradiating parts of their body with infrared laser radiation.

 Currently, in the absence of the etiological treatment of multiple sclerosis, the basis of known methods of treatment is the impact on known pathogenetic mechanisms of the disease; the impact on individual symptoms at various stages of the disease is also of certain importance [1].

 According to modern ideas, lesions of the pyramidal pathways, cerebellum, visual analyzer and pelvic organs constitute a “critical mass” of patient disability [2, 3]. In turn, their functional characteristics under conditions of a multiple demyelinating process depend on the state of the segmental and suprasegmental autonomic nervous system [4]. Recently, symptoms of lymphostasis were found in patients with PC and their relationship with the clinic of lower paraparesis was established. [5].

 The main method of treating MS is the use of narrowly targeted drugs that should restore the myelin sheath [1], as well as drugs that stimulate blood supply, lymphodynamics [3].

 Known methods of transcutaneous (percutaneous) irradiation of the body with infrared laser radiation for the treatment of various diseases, in particular, the "Laser method for the treatment of AIDS" [6]. This method is intended for the treatment of HIV-infected patients.

 In this method, a laser effect on the immune zones of the body is performed to stimulate the immune system, and with multiple sclerosis there are no significant immunity disorders. If this method is used to treat patients with multiple sclerosis, then positive results will not be possible.

 Closest to the claimed method is a method for the treatment of pelvic disorders in multiple sclerosis using laser puncture and acupuncture [7]. The specified method includes either the isolated use of laser puncture - irradiation of biologically active points "according to the standard selection of points of the anterior-median meridian, meridians passing through the anterior abdominal wall and genital area, as well as general strengthening points", or the use of laeropuncture in combination with acupuncture. Irradiation is carried out with a "helium-neon laser (wavelength 633 nm) with a power of 10 mW per square cm. With an exposure of 25 s." This method is used to treat patients with "cerebro-spinal form of multiple sclerosis, in which as a result of the disease there were difficulties in emptying the bladder or lack of peremptory urination." The use of this method in the variant of complex treatment with acupuncture and laser puncture led to a clinical improvement in the condition of patients. When using laser puncture alone, the effect of clinical improvement is not expressed [7].

 The disadvantage of this method is its limited capabilities - the temporary restoration of individual body functions, as well as the need for its combination with the method of treatment of acupuncture. In this method, there is no laser effect on the affected nerve tissue, since the radiation of a helium-neon laser does not penetrate deeper than 1-2 mm into the tissues and, at the intensities used, it cannot produce a therapeutic effect on subcutaneous tissues and organs. And with multiple sclerosis, all disorders in the functioning of individual organs and systems of the body are associated with damage to nerve tissues and the spinal cord and brain.

 The objectives of the invention is to stop the progression of the disease and, depending on the initial condition of the patient, improve his condition, increase or partially restore mobility of the limbs, normalize the work of a number of vital systems of the body, in particular, the functioning of the pelvic organs, improve vision, improve performance.

 The essence of the proposed method lies in the fact that the treatment of patients is carried out by transcutaneous (percutaneous) laser irradiation with a wavelength in the range of 700-1000 nm of the areas of the affected nerve tissue, namely, the areas of the spinal cord are irradiated percutaneously in the projection areas of the selected areas from the back and brain brain - from the occipital and temporal cranial openings, as well as the projections of the axillary and inguinal lymph nodes.

 Irradiation of the spinal cord is carried out with an average power of 20-150 mW in a scanning mode for 10-120 minutes, the brain through the occipital and temporal cranial openings for 5-60 minutes for each hole and lymph nodes for 1-10 minutes per every node. To ensure the necessary contribution of laser energy to nerve tissues that absorb laser radiation about 10 times weaker than muscle tissue, for reasonable times (less than a working day - 8 hours) in the absence of the effect of damage to surrounding tissue by laser radiation, it is recommended to use lasers with matrix emitters in in accordance with the invention "Device for percutaneous irradiation of blood and tissues" [8].

 Laser irradiation of these parts of the body is carried out sequentially in one session or in several sessions during the day. The sequence of irradiation of the sites does not matter.

 Laser therapy sessions are carried out daily for 1-3 months with possible breaks on weekends. A repetition of the course of laser treatment is possible after 3-6 months, depending on the individual characteristics of the course of the disease.

 The proposed method is combined with drug treatment.

 The technical result of using the proposed method is to stop the progression of the disease, improve the patient’s condition and partially restore the work of some affected systems and organs of the patient. A partial restoration of the normal functioning of nerve tissues is obtained both from the direct effect of laser radiation on nerve tissues, which under the influence of IR laser radiation can restore the ability to conduct signals of nerve excitation [9], and from the effect of increased microcirculation of blood in irradiated areas under the influence of laser irradiation.

 The therapeutic effect of laser irradiation of lymph nodes is expressed in the restoration of their patency, the functioning of the lymphatic drainage system and detoxification.

 Examples of treatment of patients with multiple sclerosis by laser radiation.

 1. Patient TM, 21, is ill with a cerebrospinal form of PC with a predominant visual impairment, an increase in the pyramidal cerebellar defect and pelvic organ dysfunction. The disease is 11 years old, a disabled person of the 2nd group for this disease. Treatment with traditional methods using hormones (prednisone) helped for a short time, the disease progressed. The demyelinating process is confirmed by magnetic resonance imaging of the brain.

 She gave her voluntary consent to the course of laser treatment after a demonstration session confirming the harmlessness of laser radiation, which one of the inventors carried out on himself.

 Laser treatment was carried out in the form of monotherapy on the area of the scales of the temporal bones, the large occipital foramen and the projection of the spinal cord. An improvement in the patient’s condition was noted after two weeks: “it became easier to walk, and earlier, when walking, it swayed, legs were braided, the body was like a cotton”. After 3 weeks, the good condition became stable, eyesight improved: "earlier, when the eyes were clouded, compulsory medication was required, after laser treatment 30-60 minutes of rest were enough," the work of the vestibular apparatus improved. After 1.5 months of laser treatment, subjective remission was achieved: gradual regression of motor and visual disturbances, improved functioning of the pelvic organs, which lasted more than a year. Side effects of laser therapy were not observed. Throughout the summer she lived and worked in the country. In the future, this patient was repeated a course of laser treatment also with positive results.

 2. Patient P.M., 21, suffers from a cerebro-spinal form of progressive PC, the leading neurological defect is represented by central tetraparesis with plegia of the lower extremities, 2-sided amblyopia with limited vision roles, impaired urination control. Demyelination of the central nervous system is verified using magnetic resonance imaging. Radionuclide imaging of retroperitoneal lymph nodes showed a symmetric block of lymph outflow. Disabled group 1 for this disease.

 Laser treatment was performed by irradiation of the spinal column and head; starting from the 2nd week, laser irradiation of the inguinal lymph nodes was added.

 The first positive results were noted after a week: bending of the legs while lying on the stomach, there was control over urination. Three weeks later, an improvement in vision was noted - "there is no" haze "when reading a small text." After a month of laser treatment, “elasticity” appeared in the knees when bending the legs, I was able to get on my feet with support, in the future, sometimes I could take 1-2 steps with support. Two months later, the swelling of the legs gradually began to disappear, the blue skin on the legs disappeared. Bubble atony was replaced by imperative urges to urinate, lymphostatic discirculation passed. By the end of the course of laser therapy (3 months), the ability to independently adopt a vertical position and with the help of doing several step movements appeared. Efficiency increased - printed two stories. Significantly improved well-being, vision and self-control.

 3. Patient N. M., 63 g., Cerebrospinal form of PC with a slowly progressive course, sick 12 years old, disabled person of the 2nd group for this disease. Complaints of impaired gait, poor urination control, gradually worsening vision.

 Laser therapy: irradiation of the spine and head.

 An improvement in voluntary leg movements on the same day is noted - “after the laser therapy session, the legs went easily themselves,” but this effect was short-term, no more than a day. After a month, fatigue decreased while walking, can walk without raising her legs, go up and down the stairs to the 3rd floor on her own, headaches decreased, and visual function was restored. In the summer she was able to live and work in the country, continuing laser treatment. At the end of the course of laser treatment, partial clinical remission was observed.

 4. Patient LK, 48 years old, cerebrospinal form of PC, disease duration 11 years, hospitalized: inability to move independently, to sit, stiffness in the hands, inability to service oneself. Severe lymphodynamic disturbances on both sides were verified using radionuclide scintigraphy.

 Laser treatment - irradiation of zeros of the inguinal lymph nodes was carried out.

 After the end of treatment, he can independently eat and sit. Scintigraphy shows a bilateral improvement in lymphodynamics.

 5. Patient Yu.B., 44, cerebrospinal form of PC with a slowly progressive course, the disease lasted 9 years, was hospitalized with impaired pelvic organs and moderate hemiparesis. Violation of lymphodynamics in the retroperitoneal lymph nodes on both sides is confirmed by scintigraphy.

 Laser treatment - irradiation was carried out according to the projections of the lymph nodes.

 At the end of the laser treatment course on lymphoscintigraphy, only a small degree of lymphodynamic disturbance on the right was observed, that is, a significant improvement compared with the disorder before laser treatment. According to clinical observations - an improvement in motor activity and the absence of disturbances in the work of the pelvic organs.

Sources of information
1. Savin A.A., Karlov V.A., Seleznev A.N., Kozlov S.A., Kitaeva L.V. Domestic drugs of metabolic therapy in patients with multiple sclerosis. - Journal. Neuropathol. and psychiatrist. 1995, 2, p. 37-40.

 2. Poser Charles M. Multiple sclerosis (observation and reflection). - Journal. Neuropathol. and psychiatrist. 1993, 4, p. 77-88.

 3. Gusev E.I., Demina T.L., Boyko A.N. Multiple Sclerosis -M., 1997, 463c.

 4. Khodos Kh. G., Kozhova II, Berdennikova VV On the value of autonomic nervous system dysfunction in the pathogenesis of the nervous system. - Journal. Neuropathol. and psychiatrist. 1990, 8, p. 112-115.

 5. Elchaninov A.P., Artyushkin A.V., Skoromets A.A. Diagnostic value of radionuclide imaging of the reticuloendothelial system of macrophages in patients with multiple sclerosis. - Journal. Neuropathol. and psychiatrist. 1986, 2, p. 200-203.

 6. Ovsyannikov V. A., Sizova N. V. RF patent for invention 2142828 "Laser method for the treatment of AIDS", priority from 03.15.96.

 7. Scherbakova E. G., Dzhutova E. D., Karneev A. N. Laser puncture and acupuncture in the treatment of pelvic disorders with multiple sclerosis - In Sat. abstracts of reports of the international congress "Laser and Health - 99" M ,. 1999.

 8. Ovsyannikov V.A. et al. RF patent for invention 2112567 "Device for transdermal irradiation of blood and tissues", priority from 03.15.96.

 9. Rochkind S. et al, Peripheral Nerves and Brachial Plexus Injuries: Microsurgical reconstruction and Laser Therapy - Laser Therapy Vol. 8,. 1, p. 32.

Claims (1)

 A method of treating patients with multiple sclerosis, which consists in the fact that the treatment is carried out by transcutaneous exposure to infrared laser radiation with a wavelength of 700-1000 nm and an average power of 20-150 mW on the projection of the affected areas of the spinal cord from the back in a scanning mode for 10-120 min, brain - through the occipital and temporal foramen for 5-60 min for each foramen and axillary and inguinal lymph nodes for 1-10 min for each focal point, irradiation of these areas is carried out sequentially in one session, sessions are carried out daily with possible breaks on weekends for 3-6 months.