RU2166958C2 - Лечение сахарного диабета типа ii агонистами амилина - Google Patents

Лечение сахарного диабета типа ii агонистами амилина Download PDF

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Publication number
RU2166958C2
RU2166958C2 RU97104029/14A RU97104029A RU2166958C2 RU 2166958 C2 RU2166958 C2 RU 2166958C2 RU 97104029/14 A RU97104029/14 A RU 97104029/14A RU 97104029 A RU97104029 A RU 97104029A RU 2166958 C2 RU2166958 C2 RU 2166958C2
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Russia
Prior art keywords
amylin
insulin
patients
pro
diabetes
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RU97104029/14A
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English (en)
Russian (ru)
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RU97104029A (ru
Inventor
Г. КОЛТЕРМАН Орвилл
Г. ТОМПСОН Роберт
Ф. МУЛЛЕЙН Джон
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Амилин Фармасьютикалз, Инк.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/23Calcitonins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU97104029/14A 1995-06-07 1996-06-07 Лечение сахарного диабета типа ii агонистами амилина RU2166958C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/483,188 1995-06-07
US08/483,188 US6143718A (en) 1995-06-07 1995-06-07 Treatment of Type II diabetes mellutis with amylin agonists

Publications (2)

Publication Number Publication Date
RU97104029A RU97104029A (ru) 1999-04-20
RU2166958C2 true RU2166958C2 (ru) 2001-05-20

Family

ID=23919034

Family Applications (1)

Application Number Title Priority Date Filing Date
RU97104029/14A RU2166958C2 (ru) 1995-06-07 1996-06-07 Лечение сахарного диабета типа ii агонистами амилина

Country Status (19)

Country Link
US (2) US6143718A (OSRAM)
EP (1) EP0772451B1 (OSRAM)
JP (1) JP4009319B2 (OSRAM)
AT (1) ATE228849T1 (OSRAM)
AU (1) AU721489B2 (OSRAM)
BG (1) BG101230A (OSRAM)
CA (1) CA2196999C (OSRAM)
CZ (1) CZ289043B6 (OSRAM)
DE (1) DE69625157T2 (OSRAM)
DK (1) DK0772451T3 (OSRAM)
ES (1) ES2187659T3 (OSRAM)
HU (1) HUP9700368A3 (OSRAM)
IN (1) IN181672B (OSRAM)
NO (1) NO970519L (OSRAM)
PT (1) PT772451E (OSRAM)
RU (1) RU2166958C2 (OSRAM)
SK (1) SK18697A3 (OSRAM)
WO (1) WO1996040220A1 (OSRAM)
ZA (1) ZA964838B (OSRAM)

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WO1995007098A1 (en) * 1993-09-07 1995-03-16 Amylin Pharmaceuticals, Inc. Methods for regulating gastrointestinal motility
US6143718A (en) * 1995-06-07 2000-11-07 Amylin Pharmaceuticals, Inc. Treatment of Type II diabetes mellutis with amylin agonists
US6410511B2 (en) 1997-01-08 2002-06-25 Amylin Pharmaceuticals, Inc. Formulations for amylin agonist peptides
US7312196B2 (en) 1997-01-08 2007-12-25 Amylin Pharmaceuticals, Inc. Formulations for amylin agonist peptides
US7101853B2 (en) * 1997-05-06 2006-09-05 Amylin Pharmaceuticals, Inc. Method for treating or preventing gastritis using amylin or amylin agonists
US7910548B2 (en) * 1997-06-06 2011-03-22 Amylin Pharmaceuticals, Inc. Methods for treating obesity
DK1044015T3 (da) * 1998-01-09 2008-12-08 Amylin Pharmaceuticals Inc Formuleringer med amylinagonistpeptider og insulin
US6087334A (en) * 1998-08-21 2000-07-11 Amylin Pharmaceuticals, Inc. Anti-diabetic peptides
CA2475173A1 (en) * 2002-01-08 2003-07-17 Amylin Pharmaceuticals, Inc. Use of amylin agonists to modulate triglycerides
EP1656368A4 (en) * 2002-07-09 2009-08-26 Bristol Myers Squibb Co SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS ANTIDIABETIC AGENTS AND ANTIABESITY AND THEIR MANUFACTURING PROCESS
US20050009748A1 (en) * 2003-05-14 2005-01-13 Emisphere Technologies, Inc. Compositions for delivering peptide YY and PYY agonists
WO2005014022A1 (en) * 2003-07-16 2005-02-17 Develogen Aktiengesellschaft Use of pleitrophin for preventing and treating pancreatic diseases and/or obesity and/or metabolic syndrome
ES2345113T3 (es) 2004-02-11 2010-09-15 Amylin Pharmaceuticals, Inc. Peptidos de la familia amilina y metodos para su obtencion y utilizacion.
JP2007523196A (ja) * 2004-02-20 2007-08-16 ライナット ニューロサイエンス コーポレイション Nt−4/5を用いて肥満または糖尿病を処置する方法
US7399744B2 (en) * 2004-03-04 2008-07-15 Amylin Pharmaceuticals, Inc. Methods for affecting body composition
EA015793B1 (ru) * 2005-03-11 2011-12-30 Индевус Фармасеутикалс, Инк. Способ лечения акромегалии и связанных с ней симптомов и имплант, применяемый в этом способе
US7759312B2 (en) * 2005-03-11 2010-07-20 Endo Pharmaceuticals Solutions Inc. Delivery of dry formulations of octreotide
EP1988920A1 (en) * 2006-02-02 2008-11-12 Rinat Neuroscience Corp. Methods for treating obesity by administering a trkb antagonist
CA2637826A1 (en) * 2006-02-02 2007-08-09 Rinat Neuroscience Corporation Methods for treating unwanted weight loss or eating disorders by administering a trkb agonist
MX2009006794A (es) * 2006-12-20 2009-07-02 Rinat Neuroscience Corp Agonistas del receptor tirosina quinasa b para el tratamiento de trastornos autoinmunes.
AU2007360979B2 (en) * 2007-11-14 2014-04-10 Amylin Pharmaceuticals, Llc Methods for treating obesity and obesity related diseases and disorders
WO2009158412A2 (en) * 2008-06-25 2009-12-30 Endo Pharmaceuticals Solutions Inc. Sustained delivery of exenatide and other polypeptides
AU2009262263B2 (en) 2008-06-25 2014-08-14 Endo Pharmaceuticals Solutions Inc. Octreotide implant having a release agent
LT2349324T (lt) 2008-10-17 2017-12-27 Sanofi-Aventis Deutschland Gmbh Insulino ir glp-1 agonisto derinys
JP2009149684A (ja) * 2009-03-11 2009-07-09 Amylin Pharmaceut Inc アミリン作動薬ペプチド用製剤
CN102369018B (zh) * 2009-03-12 2016-08-03 关键生物科学有限公司 糖尿病和代谢综合征的治疗
JP5832439B2 (ja) 2009-11-13 2015-12-16 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Glp−1アゴニスト、インスリン及びメチオニンを含む薬学的組成物
US20110118180A1 (en) * 2009-11-13 2011-05-19 Sanofi-Aventis Deutschland Gmbh Method of treatment of diabetes type 2 comprising add-on therapy to metformin
CN102711804B (zh) 2009-11-13 2015-09-16 赛诺菲-安万特德国有限公司 包含glp-1激动剂和甲硫氨酸的药物组合物
US20110118178A1 (en) * 2009-11-13 2011-05-19 Sanofi-Aventis Deutschland Gmbh Method of treatment of diabetes type 2 comprising add-on therapy to insulin glargine and metformin
CN103179978A (zh) 2010-08-30 2013-06-26 赛诺菲-安万特德国有限公司 Ave0010用于制造供治疗2型糖尿病用的药物的用途
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
WO2013030160A1 (en) 2011-08-29 2013-03-07 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for use in glycemic control in diabetes type 2 patients
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
BR102013017626A2 (pt) * 2013-06-14 2015-02-10 Univ Rio De Janeiro Bioconjugados não aglomerantes de amilinomiméticos com polietilenoglicol, uso de bioconjugados não aglomerantes de amilinomiméticos com polietilenoglicol, composições farmacêuticas de baixa toxicidade, adjuvante para a prevenção ou tratamento das doenças, medicamento, método de tratamento ou prevenção de doenças.
CN106687474A (zh) * 2014-09-04 2017-05-17 诺和诺德股份有限公司 新型胰淀素和降钙素受体激动剂
MA41138B1 (fr) 2014-12-12 2023-07-31 Sanofi Aventis Deutschland Formulation à rapport fixe d'insuline glargine/lixisenatide
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患之治療

Citations (1)

* Cited by examiner, † Cited by third party
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US5281581A (en) * 1988-01-11 1994-01-25 Amylin Pharmaceuticals, Inc. Treatment of insulin resistance

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GB8720115D0 (en) * 1987-08-26 1987-09-30 Cooper G J S Treatment of diabetes mellitus
US5367052A (en) * 1987-04-27 1994-11-22 Amylin Pharmaceuticals, Inc. Amylin peptides
US5175145A (en) * 1988-08-26 1992-12-29 Amylin Pharmaceuticals, Inc. Treatment of diabetes mellitus with amylin agonists
US5264372A (en) * 1991-03-15 1993-11-23 Amylin Pharmaceuticals, Inc. Receptor-based screening methods for amylin agonists and antagonists
US5321008A (en) * 1991-01-10 1994-06-14 Amylin Pharmaceuticals, Inc. Methods and compositions for treatment of diabetes mellitus, hypoglycemia, and other conditions
US5234906A (en) * 1991-01-10 1993-08-10 Amylin Pharmaceuticals, Inc. Hyperglycemic compositions
HU222249B1 (hu) * 1991-03-08 2003-05-28 Amylin Pharmaceuticals Inc. Eljárás amilin agonista peptidszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
ES2161697T3 (es) * 1991-11-19 2001-12-16 Amylin Pharmaceuticals Inc Peptidos agonistas de amilina y usos de los mismos.
US5376638A (en) * 1992-09-01 1994-12-27 Amylin Pharmaceuticals, Inc. Methods for treating renin-related disorders with amylin antagonists
WO1995007098A1 (en) * 1993-09-07 1995-03-16 Amylin Pharmaceuticals, Inc. Methods for regulating gastrointestinal motility
US6143718A (en) * 1995-06-07 2000-11-07 Amylin Pharmaceuticals, Inc. Treatment of Type II diabetes mellutis with amylin agonists
US6087334A (en) 1998-08-21 2000-07-11 Amylin Pharmaceuticals, Inc. Anti-diabetic peptides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5281581A (en) * 1988-01-11 1994-01-25 Amylin Pharmaceuticals, Inc. Treatment of insulin resistance

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Применение акарбозы и амилина в терапии сахарного диабета. - Медицинские новости, 1997, № 10, стр. 58-60. *

Also Published As

Publication number Publication date
HUP9700368A2 (hu) 1998-06-29
AU6268596A (en) 1996-12-30
ZA964838B (en) 1997-02-24
CZ289043B6 (cs) 2001-10-17
US6417164B1 (en) 2002-07-09
EP0772451B1 (en) 2002-12-04
PT772451E (pt) 2003-04-30
EP0772451A4 (en) 1998-09-30
JPH10503785A (ja) 1998-04-07
EP0772451A1 (en) 1997-05-14
DE69625157D1 (de) 2003-01-16
US6143718A (en) 2000-11-07
WO1996040220A1 (en) 1996-12-19
DK0772451T3 (da) 2003-01-06
JP4009319B2 (ja) 2007-11-14
IN181672B (OSRAM) 1998-08-29
CZ33797A3 (en) 1997-07-16
SK18697A3 (en) 1998-02-04
NO970519L (no) 1997-04-07
NO970519D0 (no) 1997-02-05
ES2187659T3 (es) 2003-06-16
CA2196999C (en) 2012-09-04
HUP9700368A3 (en) 2001-03-28
AU721489B2 (en) 2000-07-06
HU9700368D0 (en) 1997-04-28
BG101230A (en) 1997-10-31
DE69625157T2 (de) 2003-04-17
CA2196999A1 (en) 1996-12-19
ATE228849T1 (de) 2002-12-15

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Effective date: 20131003

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Effective date: 20150608