RU2149636C1 - Method for treating chronic diseases of gastroenteric tract - Google Patents

Abstract

FIELD: medicine. SUBSTANCE: method involves administering magnetized mineral water of low mineral concentration. The water is magnetized in glass reservoir by rotating it in permanent magnetic field. Magnetic field intensity is equal to 0.1-0.2 Tesla units, rotation frequency is 0.75-1.25 Hz, time duration is 30-40 s. Water is drunk 2-3 times a day. The whole course is 12-14 days long. EFFECT: reduced pathologic mucus production; adjusted gastric juice secretion. 3 tbl

Description

 The invention relates to medicine, namely to physiotherapy, and relates to methods for treating chronic diseases of the gastrointestinal tract.

 Known methods of treating chronic gastroduodenitis and non-calculous cholecystitis in children and adults using the drinking intake of mineral water of low mineralization, as well as the combined effect of the internal intake of mineral water and an alternating magnetic field on the organs of the gastroduodenal and hepatobiliary zones [3].

The closest in technical essence to the claimed is a method of treating chronic diseases of the gastrointestinal tract by drinking mineral water of low mineralization of 100-150 ml, at a temperature of 40 ^o C 30-40 minutes before meals, 2 times a day, for 26 -30 days [5].

The disadvantage of this method is that it:
- does not have a quick action, stopping the inflammatory process in the mucous membrane of the stomach and biliary tract;
- does not have a sufficient stimulating effect on gastric secretion in hypocidal conditions;
- has a mild choleretic effect;
- gives insufficiently long remission.

 Common in the claimed method and prototype is the use of low-saline water inside for chronic gastroduodenitis and non-calculous cholecystitis in children and adults.

DISTINCTIVE SIGNS OF THE PROVIDED METHOD ARE:
1) the use of low-mineralization activated mineral constant water magnetic field with a certain arrangement of procedures;
2) the drug is given at room temperature 20-22 ^o C.

The method is carried out as follows: patients with chronic diseases of the gastrointestinal tract are prescribed oral administration of magnetized mineral water with a salinity of 2-5 g / l, in an amount of 100-150 ml per reception, depending on the age and body weight of the patient, for 30-40 min before meals, at a temperature of 20-22 ^o C, 2-3 times a day, for 12-14 days, while the solution is magnetized in a glass container by rotating it in a magnetic field with an induction of 0.1-0.2 T, formed by permanent magnets located on opposite sides of the container, with a frequency of Ia 0.75-1.25 Hz for 30-40 seconds.

 SUBSTANTIATION OF DISTINCTIVE SIGNS.

The use of activation by a constant magnetic field of mineral water can significantly improve its healing properties. It is known that when fluid lines cross the magnetic field lines, hydrated shells are discharged from particles of mineral substances, as a result of which freshly bare surfaces appear in the solution, which act as a catalyst and accelerate chemical and biological processes [1,4]. The effectiveness of the internal intake of magnetized mineral water is due to its effect on the organ and the body as an information factor with a frequency spectrum adequate in amplitude-frequency characteristics to a particular biological system. This was manifested both in the membrane-stabilizing effect of water (a decrease in plasma markers of damage to aspartate aminotransferases and alanine aminotransferases / ACT and ALT /), and in the correction of the body's immune status (increase in the content of T-lymphocytes, T-helpers, T-suppressors), as well as general and local anti-inflammatory effect (decrease in initially high white blood cell count). Based on the first results obtained, it can be concluded that magnetized mineral water, in contrast to non-magnetized, has a normalizing effect on gastric secretion (a decrease in the initially increased acidity of gastric juice, and in patients with an initially reduced acid formation stimulation of acid and pepsin formation was noted). The temperature of mineral water 20-22 ^o C allows you to save the associates (clusters) of water, that is, to increase its structure. At the same time, it is known that for a number of diseases the body lacks precisely structured water. The initial magnetization of water at room temperature increases the efficiency of magnetic treatment and increases the duration of conservation of its altered structure [2]. The use of water with low salinity practically eliminated undesirable side effects that occur when using water with greater salinity. Reception of magnetized mineral water 30-40 minutes before a meal allowed the therapeutic effect to be realized, which decreases with a meal. Under observation were 62 adult patients with chronic non-calculous cholecystitis in the phase of decaying exacerbation and 36 children with chronic gastroduodenitis confirmed endoscopically, aged 8 to 14 years. Of these, 22 people with reduced acid-forming function of the stomach (14 in the stage of remission and submission, 8 in the stage of exacerbation), 6 people with normal acid-forming function (in the stage of remission), 8 people with increased acid formation (3 in the stage of remission, 5 with exacerbation of the process ) The control group consisted of 15 patients with chronic cholecystitis and 14 children with chronic gastroduodenitis who received non-magnetized water. Before and after treatment, each patient had an analysis of complaints and a clinical picture. Patients with chronic gastroduodenitis underwent fractional gastric sounding. In the obtained gastric contents, the total acidity was determined by the method of pH-metry with recalculation of the indicators according to the table of pH-concentration ratios of H ions of gastric juice (Kalinichenko V.V. 1968). The function of the main cells was evaluated by the content of pepsin in the juice (V. Tugolukov). Acid mucopolysaccharides (diphenylamine reaction of Dishe 1966) were also determined in the gastric juice. Patients with chronic non-calculous cholecystitis were determined by the parameters of fractional duodenal sounding, blood biochemical parameters: malondialdehyde (MDA), ALT, ACT. We studied the effect of magnetized and non-magnetized mineral water on the body's immune status. The results of these studies are shown in tables 1, 2, 3.

 The results showed that the proposed method has a positive effect on the dynamics of the clinical picture of chronic diseases of the gastrointestinal tract: after a course of treatment by the claimed method, 92% of patients stopped complaining of dyspeptic symptoms (nausea, heartburn, belching), 85% stopped complaining of pain in the epigastrium and right hypochondrium. Soreness on palpation of the epigastrium and pyloroduodenal zone disappeared in 40% of patients, in the others it significantly decreased. In 30% of patients, the cystic symptoms of Kehr and Ortner disappeared. However, all patients improved overall well-being, increased appetite.

 The above indicators indicate the anti-inflammatory effect of the proposed method, which is expressed in the reduction of pathological mucus formation (acid mucopolysaccharides). And also the inventive method has a corrective effect on gastric secretion, as indicated by rates of debit hour and pepesin.

 From the data given in the table it is seen that magnetized mineral water has a more pronounced corrective effect on the rate of excretion of cystic bile, as well as local anti-inflammatory effect, which is manifested in a significant reduction in leukocytosis in bile.

The data in the table show that magnetized water has a more pronounced membrane-stabilizing, immunostimulating and anti-inflammatory effect than non-magnetized mineral water
EXAMPLE 1. Nina Petukhova, 11 years old, medical history 86. Received treatment 12.03.96, with a diagnosis of chronic gastroduodenitis with decreased acid-forming stomach function, in the stage of incomplete remission. Concomitant diseases: chronic cholecystitis, chronic compensated tonsillitis. Sick for 3 years, constantly worried about pain in the epigastrium and right hypochondrium, 6 months ago she was in hospital treatment, where opisthorchiasis was detected and treated. Upon receipt of a complaint of fatigue, weakness, headache, nausea, abdominal pain before and after eating. Objectively: the skin is clean, the sclera is icteric, the tongue is densely covered with white coating, pain in the epigastrium and pyloroduodenal zone is palpated, the liver is not enlarged, painful on palpation, the symptoms of Kehr, Ortner are positive. General clinical blood and urine tests within the age norm. Gastric sounding showed a decrease in acid-forming and secretory functions of the stomach: hourly voltage of 20 ml, total acidity 3.14 mmol / l, flow rate-hour 0.062, pepsin 0.08 mmol / l. As a result of a biochemical study, the content of mucoproteins was 0.176 mM / L, of the local immunity factors SYgA 0.47 g / L. The visually obtained gastric contents are cloudy with flakes, mucus strands and streaks of blood. Coarse irregular waves with a frequency of 3.4 per minute and an average amplitude of 0.4 mV were recorded on the electrogastrogram.

The child underwent a course of treatment by the claimed method, namely: drinking low-saline water with a salinity of 2 g / l, activated by a constant magnetic field by induction of 0.2 T, at a temperature of 20 ^o C, 100 ml per reception, 2 times a day, for 30 minutes before meals, for 14 days. After this treatment, complaints of asthenic nature stopped, as well as complaints of nausea and abdominal pain, the tongue cleared of plaque. Palpation of the abdomen did not reveal pain in the epigastrium and pyloroduodenal zone, the liver is painless, the symptoms of Kera, Ortner are negative. The results of gastric sounding showed normalization of the secretory activity of the stomach: hourly voltage of 20 ml, total acidity of 20 mm / l, flow rate-hour of 0.8. The pepsin content in the juice increased to 0.6 mM / L, and indicators indicating the presence of inflammation in the gastric wall decreased: mucoproteins to 0.112 mM / L, SYgA to 0.28 g / L. Visually, the gastric contents are gray, transparent with a little mucus. Waves with a frequency of 2.8 per minute and an average amplitude of 0.32 mV were recorded on the electro-gastrographic curve. After treatment, exacerbations were not observed for 10 months.

 EXAMPLE 2

 Patient Novoseltsev O.A. Born 1972, medical history N 336, was admitted for treatment on 02/13/96 with a diagnosis of chronic non-calculous cholecystitis in the stage of decaying exacerbation. With complaints of general malaise, headache, increased irritability, pain in the right hypochondrium, dyspeptic disorders with a slight violation of the diet (intake of fatty or spicy foods). Three years ago I was treated in a clinic where I was diagnosed with chronic non-calculous cholecystitis in the acute stage. An ultrasound scan confirms the presence of signs of chronic non-calculous cholecystitis. I did not receive spa treatment. An objective examination revealed: dry skin, the tongue is coated with a white coating, the type of constitution is asthenic. The abdomen is painful on palpation in the right hypochondrium, the point of the gallbladder. The liver is not enlarged, the symptoms of Ortner and Mussi are positive. The spleen is not palpable. A paraclinical study found: an increase in total bilirubin to 28 mM / L and alkaline phosphatase to 350 ME, an increase in malondialdehyde activity to 4.2 mM / L. The content of direct bilirubin, the level of aminotransferases (ALT and ACT) was within normal limits. After duodenal sounding by microscopic examination of bile, in portion B there was an increase in leukocytes to 15 in the field of view, a large amount of sand. In the blood, a decrease in T- and B-lymphocytes to 33% and 19.5%, as well as a decrease in the content of T-helpers and T-suppressors to 18% and 14.8%, respectively.

The patient was prescribed treatment in accordance with the claimed method, namely: the internal intake of mineral water "Karachinskaya" (mineralization 3 g / l), activated by a magnetic field by induction of 0.2 T, at a temperature of 22 ^o C, 150 ml, 3 times a day , 30 minutes before meals, daily, for 12 days. As a result of treatment, the patient's well-being improved significantly, the patient gained 1 kg in weight. The palpation of the liver is painless, the positive symptoms of Ortner and Musse disappeared. The content of initially elevated bilirubin and alkaline phosphatase decreased to normal. The activity of initially elevated malondialdehyde was normalized, and T- and B-cell immunity indices increased. After a course of treatment, a single leukocyte content in the field of view and a small amount of sand are microscopically observed in the contents of duodenal sounding (portion B). The patient was discharged with significant improvement; after discharge, an exacerbation of the process is not observed during the year.

ADVANTAGES OF THE INVENTED METHOD:
a) the method is more economical, since the course of treatment with magnetized mineral water is 2 times less than non-magnetized;
b) achievement of stable remission up to 10-12 months;
c) a more pronounced choleretic effect;
g) a normalizing effect on gastric secretion.

 LITERARY SOURCES.

 1. Efanov L. N. On the level of interaction of water with an external magnetic field. Questions of the theory and practice of magnetic treatment of water and water systems. M., 1969 p. 8-9.

 2. Klassen V.I. Magnetization of water systems. M., 1978.

 3. Kucherova T.Ya. A method for the rehabilitation of patients radically operated on for cancer of the stomach. Patent N 2043126 dated 09/10/95, bull. N 25.

 4. Mikhelson M. L. Merkulova I. U. On the biological and bactericidal action of magnetized water. Questions of balneology, physiotherapy and physiotherapy. 1994, N 2, p. 35-37.

 5. Shemetilo I.G. Vorobiev M.G. Therapeutic mineral water. L., Medicine, 1982.

Claims (1)

A method of treating chronic diseases of the gastrointestinal tract, including the intake of mineral water of low mineralization in an amount of 100 to 150 ml per intake, 30 to 40 minutes before meals, characterized in that magnetized mineral water is taken by mineralization of 2 to 3 g / l, which is magnetized in a glass container by rotating it in a magnetic field with an induction of 0.1 - 0.2 T, formed by permanent magnets located on opposite sides of the vessel, with a rotation frequency of 0.75 - 1.25 Hz, for 30 - 40 s water intake is carried out 2 to 3 times per day b, at its temperature of 20 - 22 ^o C, the course of 12 - 14 days.

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