RU2144921C1 - Кристаллическая форма цвиттериона тровафлоксацина и способ ее получения - Google Patents

Кристаллическая форма цвиттериона тровафлоксацина и способ ее получения Download PDF

Info

Publication number
RU2144921C1
RU2144921C1 RU98103873/04A RU98103873A RU2144921C1 RU 2144921 C1 RU2144921 C1 RU 2144921C1 RU 98103873/04 A RU98103873/04 A RU 98103873/04A RU 98103873 A RU98103873 A RU 98103873A RU 2144921 C1 RU2144921 C1 RU 2144921C1
Authority
RU
Russia
Prior art keywords
polymorph
hygroscopic
compound
formula
pentahydrate
Prior art date
Application number
RU98103873/04A
Other languages
English (en)
Russian (ru)
Other versions
RU98103873A (ru
Inventor
Джон Мелдрем Аллен Дуглас (US)
Джон Мелдрем Аллен Дуглас
Брунинг Джозеф Дэвид (US)
Брунинг Джозеф Дэвид
Норрис Тимоти (US)
Норрис Тимоти
Original Assignee
Пфайзер Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Инк. filed Critical Пфайзер Инк.
Publication of RU98103873A publication Critical patent/RU98103873A/ru
Application granted granted Critical
Publication of RU2144921C1 publication Critical patent/RU2144921C1/ru

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Physical Water Treatments (AREA)
  • Processing Of Solid Wastes (AREA)
RU98103873/04A 1995-08-29 1996-07-29 Кристаллическая форма цвиттериона тровафлоксацина и способ ее получения RU2144921C1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US297595P 1995-08-29 1995-08-29
US60/002975 1995-08-29
US60/002,975 1995-08-29
PCT/IB1996/000756 WO1997007800A1 (en) 1995-08-29 1996-07-29 Zwitterionic forms of trovafloxacin

Publications (2)

Publication Number Publication Date
RU98103873A RU98103873A (ru) 1999-12-10
RU2144921C1 true RU2144921C1 (ru) 2000-01-27

Family

ID=21703460

Family Applications (1)

Application Number Title Priority Date Filing Date
RU98103873/04A RU2144921C1 (ru) 1995-08-29 1996-07-29 Кристаллическая форма цвиттериона тровафлоксацина и способ ее получения

Country Status (30)

Country Link
EP (1) EP0850060A1 (sh)
JP (1) JP3188476B2 (sh)
KR (1) KR100343909B1 (sh)
CN (1) CN1190889A (sh)
AP (1) AP636A (sh)
AR (1) AR003985A1 (sh)
AU (1) AU704115B2 (sh)
BR (1) BR9609998A (sh)
CA (1) CA2229786C (sh)
CO (1) CO4480739A1 (sh)
CZ (1) CZ56698A3 (sh)
DZ (1) DZ2087A1 (sh)
GT (1) GT199600072A (sh)
HR (1) HRP960395B1 (sh)
HU (1) HUP9900170A3 (sh)
IL (1) IL122651A (sh)
MA (1) MA23966A1 (sh)
MY (1) MY113874A (sh)
NO (1) NO309814B1 (sh)
NZ (1) NZ312199A (sh)
OA (1) OA10669A (sh)
PE (1) PE12598A1 (sh)
PL (1) PL325170A1 (sh)
RU (1) RU2144921C1 (sh)
SK (1) SK23898A3 (sh)
TN (1) TNSN96109A1 (sh)
TR (1) TR199800339T1 (sh)
WO (1) WO1997007800A1 (sh)
YU (1) YU48396A (sh)
ZA (1) ZA967282B (sh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HN1998000106A (es) 1997-08-01 1999-01-08 Pfizer Prod Inc Composiciones parenterales de alatroflaxacino
US7019142B2 (en) 1998-01-16 2006-03-28 Pfizer Inc. Process for preparing naphthyridones and intermediates
PA8466701A1 (es) * 1998-01-21 2000-09-29 Pfizer Prod Inc Comprimido de mesilato de trovafloxacino
US6114531A (en) * 1998-07-28 2000-09-05 Pfizer Inc. Process for preparing quinolone and naphthyridone carboxylic acids
HN1999000141A (es) * 1998-09-03 2000-06-19 Pfizer Prod Inc Procedimiento para preparar sales de trovafloxacina de adicion de acidos.
US6239141B1 (en) 1999-06-04 2001-05-29 Pfizer Inc. Trovafloxacin oral suspensions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164402A (en) * 1989-08-16 1992-11-17 Pfizer Inc Azabicyclo quinolone and naphthyridinone carboxylic acids

Also Published As

Publication number Publication date
TR199800339T1 (xx) 1998-06-22
KR19990044232A (ko) 1999-06-25
AU704115B2 (en) 1999-04-15
MX9801664A (es) 1998-08-30
JPH10511692A (ja) 1998-11-10
IL122651A0 (en) 1998-08-16
MY113874A (en) 2002-06-29
HUP9900170A2 (hu) 1999-05-28
EP0850060A1 (en) 1998-07-01
NO980862D0 (no) 1998-02-27
CA2229786A1 (en) 1997-03-06
CN1190889A (zh) 1998-08-19
CZ56698A3 (cs) 1999-02-17
IL122651A (en) 2000-02-17
HRP960395A2 (en) 1998-06-30
ZA967282B (en) 1998-03-02
YU48396A (sh) 1998-12-23
CO4480739A1 (es) 1997-07-09
JP3188476B2 (ja) 2001-07-16
GT199600072A (es) 1998-02-14
BR9609998A (pt) 1999-07-06
CA2229786C (en) 2002-02-19
HRP960395B1 (en) 2001-12-31
AU6367696A (en) 1997-03-19
SK23898A3 (en) 1999-05-07
AR003985A1 (es) 1998-09-30
KR100343909B1 (ko) 2003-04-10
WO1997007800A1 (en) 1997-03-06
DZ2087A1 (fr) 2002-07-22
AP9600853A0 (en) 1996-10-31
HUP9900170A3 (en) 1999-11-29
TNSN96109A1 (fr) 2005-03-15
AP636A (en) 1998-04-09
OA10669A (en) 2000-11-06
NO980862L (no) 1998-02-27
MA23966A1 (fr) 1997-04-01
NZ312199A (en) 1999-06-29
PL325170A1 (en) 1998-07-06
NO309814B1 (no) 2001-04-02
PE12598A1 (es) 1998-03-20

Similar Documents

Publication Publication Date Title
RU2125571C1 (ru) СОЛЬ 7-([1α,5α,6α]-6-АМИНО-3-АЗАБИЦИКЛО [3.1.0] ГЕКС-3-ИЛ)-6-ФТОР-1-(2,4-ДИФТОРФЕНИЛ)-1,4- ДИГИДРО-4-ОКСО-1,8-НАФТИРИДИН-3-КАРБОНОВОЙ И МЕТАНСУЛЬФОНОВОЙ КИСЛОТ И СПОСОБ ЕЕ ПОЛУЧЕНИЯ
RU2144921C1 (ru) Кристаллическая форма цвиттериона тровафлоксацина и способ ее получения
DK170645B1 (da) Krystallinsk vandfrit amoxycillin, fremgangsmåde til fremstilling heraf, samt præparater indeholdende dette
US6066647A (en) Zwitterionic forms of trovafloxacin
US6514965B1 (en) Substituted 1-benzazepines and derivatives thereof
RU2151152C1 (ru) Полиморфы 6-n-(l-ala-l-ala)-тровафлоксацина
SK64098A3 (en) Production of a salt of clavulanic acid
JP2005501819A (ja) ピンク色化合物の形成を制限する塩酸パロキセチン調製プロセス
JPS59199693A (ja) インドリルグリシルセフアロスポリン誘導体
MXPA98001664A (en) Zwitterionic forms of trovafloxacin, procedure for its preparation, compositions that contain them and use of the mis
WO2002018344A1 (fr) Nouveaux derives esteriques ou amidiques
CA2258960C (en) A process for preparing naphthyridones and intermediates
JPS6230776A (ja) キノリン誘導体、そのエステルおよびその塩
AP788A (en) Novel crystal form of anhydrous 7-(1a, 5a, 6a)-6-Amino-3-Azabicyclo(3.1.0) hex-3-YI)-6-Fluoro-1-(2,4- Difluorophenyl)-1,4-Dihydro-4-Oxo-1, 8-Naphthyridine-3-Carboxylic Acid, Methanesulfonic acid salt.
MXPA98001665A (en) Polymorphoses of profarmaco of 6-n- (l-ala-l-ala) -trovafloxacin, procedure for its preparation and use of mis

Legal Events

Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20030730