RU2142274C1 - Агент для лечения состояния тревоги - Google Patents

Агент для лечения состояния тревоги Download PDF

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Publication number
RU2142274C1
RU2142274C1 RU94034109A RU94034109A RU2142274C1 RU 2142274 C1 RU2142274 C1 RU 2142274C1 RU 94034109 A RU94034109 A RU 94034109A RU 94034109 A RU94034109 A RU 94034109A RU 2142274 C1 RU2142274 C1 RU 2142274C1
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RU
Russia
Prior art keywords
anxiety
compound
animals
test
oxo
Prior art date
Application number
RU94034109A
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English (en)
Russian (ru)
Other versions
RU94034109A (ru
Inventor
Вульферт Эрнст
Гобер Жан
Гауэр Алма
Коссеман Эрик
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Юцб
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Юцб filed Critical Юцб
Publication of RU94034109A publication Critical patent/RU94034109A/ru
Application granted granted Critical
Publication of RU2142274C1 publication Critical patent/RU2142274C1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
RU94034109A 1993-09-24 1994-09-23 Агент для лечения состояния тревоги RU2142274C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939319732A GB9319732D0 (en) 1993-09-24 1993-09-24 Use of (s)-alpha-ethyl-2-oxo-l-pyrrolidineacetamide for the treatment of anxiety
GB9319732.5 1993-09-24

Publications (2)

Publication Number Publication Date
RU94034109A RU94034109A (ru) 1997-12-10
RU2142274C1 true RU2142274C1 (ru) 1999-12-10

Family

ID=10742476

Family Applications (1)

Application Number Title Priority Date Filing Date
RU94034109A RU2142274C1 (ru) 1993-09-24 1994-09-23 Агент для лечения состояния тревоги

Country Status (17)

Country Link
US (1) US5447952A (enExample)
EP (1) EP0645139B1 (enExample)
JP (1) JP3688735B2 (enExample)
KR (1) KR950007848A (enExample)
AT (1) ATE191849T1 (enExample)
AU (1) AU672334B2 (enExample)
CA (1) CA2132509A1 (enExample)
DE (1) DE69424009T2 (enExample)
ES (1) ES2145818T3 (enExample)
GB (1) GB9319732D0 (enExample)
HU (1) HU217124B (enExample)
NO (1) NO943521L (enExample)
NZ (1) NZ264506A (enExample)
RU (1) RU2142274C1 (enExample)
SG (1) SG86284A1 (enExample)
TW (1) TW283642B (enExample)
ZA (1) ZA947444B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5525347A (en) * 1995-01-31 1996-06-11 Medical University Of South Carolina Composition and methods for treating performance anxiety
CA2392879C (en) 1999-12-01 2005-03-29 Ucb, S.A. A pyrrolidineacetamide derivative alone or in combination for treatment of cns disorders
GB0004297D0 (en) 2000-02-23 2000-04-12 Ucb Sa 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses
ES2317452T3 (es) * 2006-01-24 2009-04-16 Teva Pharmaceutical Industries Limited Formulaciones de levetiracetam y procedimientos para su preparacion.
EA015256B1 (ru) * 2006-03-15 2011-06-30 Актелион Фармасьютикалз Лтд. Производные тетрагидроизохинолина для повышения функции памяти
EP2051696A2 (en) * 2006-08-18 2009-04-29 Morton Grove Pharmaceuticals, Inc. Stable liquid levetiracetam compositions and methods
US8106215B2 (en) * 2007-07-03 2012-01-31 Actelion Pharmaceuticals Ltd. 3-aza-bicyclo[3.3.0]octane compounds
KR20100046047A (ko) * 2007-07-27 2010-05-04 액테리온 파마슈티칼 리미티드 2-아자-비시클로[3.3.0]옥탄 유도체
EP2346500B1 (en) 2008-10-16 2017-05-17 The Johns Hopkins University Methods and compositions for improving cognitive function
US8191547B2 (en) * 2008-10-23 2012-06-05 S-2Tech Llc Portable solar-heating system having an inflatable solar collector
US20100172979A1 (en) * 2008-12-24 2010-07-08 Zhongshui Yu Controlled-release formulations
US20100159009A1 (en) * 2008-12-24 2010-06-24 Zhongshui Yu Controlled-release formulations
EP2533645B1 (en) * 2010-02-09 2016-07-27 The Johns Hopkins University Methods and compositions for improving cognitive function
EP2672822A4 (en) * 2011-02-09 2014-08-27 Univ Johns Hopkins METHOD AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTIONS
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
US10806717B2 (en) 2013-03-15 2020-10-20 The Johns Hopkins University Methods and compositions for improving cognitive function
CA2904767C (en) 2013-03-15 2022-06-21 Agenebio, Inc. Methods and compositions for improving cognitive function
EA034167B8 (ru) 2015-05-22 2021-04-27 Эйджинбайо, Инк. Фармацевтические композиции леветирацетама пролонгированного высвобождения
JP2022510363A (ja) * 2018-12-04 2022-01-26 メティス ファーマシューティカルズ アクチェンゲゼルシャフト （ｒ）－２－（２－オキソピロリジン－１－イル）ブタンアミドと（ｓ）－２－（２－オキソピロリジン－１－イル）ブタンアミドを非ラセミ比で含む相乗的組成物

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0162036A1 (fr) * 1984-05-15 1985-11-21 U C B, S.A. (S)-alpha-éthyl-2-oxo-1-pyrrolidineacétamide
SU1320707A1 (ru) * 1985-01-24 1987-06-30 Ивано-Франковский Институт Нефти И Газа Способ определени износостойкости материалов ма тниковым склерометром
SU1414845A1 (ru) * 1984-03-23 1988-08-07 Всесоюзный Научно-Исследовательский Химико-Фармацевтический Институт Им.С.Орджоникидзе 1-Тиокарбамоилметилпирролидин-2-тион,обладающий ноотропной активностью, и способ его получени
EP0408782A1 (en) * 1989-07-18 1991-01-23 Nauchnoissledovatelski Chimikopharmatzevtichen Institut Antihypoxic agent
US5143912A (en) * 1990-08-21 1992-09-01 Hoffmann-La Roche, Inc. Tricyclic pyridone derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8827389D0 (en) 1988-11-23 1988-12-29 Ucb Sa Process for preparation of(s)alpha-ethyl-2-oxo-1-pyrrolidineacetamide

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1414845A1 (ru) * 1984-03-23 1988-08-07 Всесоюзный Научно-Исследовательский Химико-Фармацевтический Институт Им.С.Орджоникидзе 1-Тиокарбамоилметилпирролидин-2-тион,обладающий ноотропной активностью, и способ его получени
EP0162036A1 (fr) * 1984-05-15 1985-11-21 U C B, S.A. (S)-alpha-éthyl-2-oxo-1-pyrrolidineacétamide
SU1320707A1 (ru) * 1985-01-24 1987-06-30 Ивано-Франковский Институт Нефти И Газа Способ определени износостойкости материалов ма тниковым склерометром
EP0408782A1 (en) * 1989-07-18 1991-01-23 Nauchnoissledovatelski Chimikopharmatzevtichen Institut Antihypoxic agent
US5143912A (en) * 1990-08-21 1992-09-01 Hoffmann-La Roche, Inc. Tricyclic pyridone derivatives

Also Published As

Publication number Publication date
HUT68299A (en) 1995-06-28
NO943521D0 (no) 1994-09-22
NZ264506A (en) 1997-09-22
DE69424009D1 (de) 2000-05-25
ATE191849T1 (de) 2000-05-15
EP0645139A1 (fr) 1995-03-29
AU7416994A (en) 1995-04-06
CA2132509A1 (en) 1995-03-25
US5447952A (en) 1995-09-05
HU217124B (hu) 1999-11-29
JPH07149639A (ja) 1995-06-13
NO943521L (no) 1995-03-27
DE69424009T2 (de) 2000-09-14
KR950007848A (ko) 1995-04-15
ZA947444B (en) 1995-05-11
GB9319732D0 (en) 1993-11-10
TW283642B (enExample) 1996-08-21
EP0645139B1 (fr) 2000-04-19
ES2145818T3 (es) 2000-07-16
SG86284A1 (en) 2002-02-19
AU672334B2 (en) 1996-09-26
JP3688735B2 (ja) 2005-08-31

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