RU2142274C1 - Агент для лечения состояния тревоги - Google Patents

Агент для лечения состояния тревоги Download PDF

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Publication number
RU2142274C1
RU2142274C1 RU94034109A RU94034109A RU2142274C1 RU 2142274 C1 RU2142274 C1 RU 2142274C1 RU 94034109 A RU94034109 A RU 94034109A RU 94034109 A RU94034109 A RU 94034109A RU 2142274 C1 RU2142274 C1 RU 2142274C1
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RU
Russia
Prior art keywords
anxiety
compound
animals
test
oxo
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RU94034109A
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English (en)
Russian (ru)
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RU94034109A (ru
Inventor
Вульферт Эрнст
Гобер Жан
Гауэр Алма
Коссеман Эрик
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Юцб
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Publication of RU94034109A publication Critical patent/RU94034109A/ru
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Publication of RU2142274C1 publication Critical patent/RU2142274C1/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
RU94034109A 1993-09-24 1994-09-23 Агент для лечения состояния тревоги RU2142274C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9319732.5 1993-09-24
GB939319732A GB9319732D0 (en) 1993-09-24 1993-09-24 Use of (s)-alpha-ethyl-2-oxo-l-pyrrolidineacetamide for the treatment of anxiety

Publications (2)

Publication Number Publication Date
RU94034109A RU94034109A (ru) 1997-12-10
RU2142274C1 true RU2142274C1 (ru) 1999-12-10

Family

ID=10742476

Family Applications (1)

Application Number Title Priority Date Filing Date
RU94034109A RU2142274C1 (ru) 1993-09-24 1994-09-23 Агент для лечения состояния тревоги

Country Status (17)

Country Link
US (1) US5447952A (enExample)
EP (1) EP0645139B1 (enExample)
JP (1) JP3688735B2 (enExample)
KR (1) KR950007848A (enExample)
AT (1) ATE191849T1 (enExample)
AU (1) AU672334B2 (enExample)
CA (1) CA2132509A1 (enExample)
DE (1) DE69424009T2 (enExample)
ES (1) ES2145818T3 (enExample)
GB (1) GB9319732D0 (enExample)
HU (1) HU217124B (enExample)
NO (1) NO943521L (enExample)
NZ (1) NZ264506A (enExample)
RU (1) RU2142274C1 (enExample)
SG (1) SG86284A1 (enExample)
TW (1) TW283642B (enExample)
ZA (1) ZA947444B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5525347A (en) * 1995-01-31 1996-06-11 Medical University Of South Carolina Composition and methods for treating performance anxiety
YU37602A (sh) 1999-12-01 2005-07-19 Ucb S.A. Derivat pirolidinacetamida sam ili u kombinaciji za tretman poremećaja cns
GB0004297D0 (en) * 2000-02-23 2000-04-12 Ucb Sa 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses
ATE413875T1 (de) * 2006-01-24 2008-11-15 Teva Pharma Zusammensetzungen enthaltend levetiracetam und verfahren zu deren herstellung.
AU2007226203A1 (en) * 2006-03-15 2007-09-20 Actelion Pharmaceuticals Ltd Tetrahydroisoquinoline derivatives to enhance memory function
EP2051696A2 (en) * 2006-08-18 2009-04-29 Morton Grove Pharmaceuticals, Inc. Stable liquid levetiracetam compositions and methods
PL2164847T3 (pl) * 2007-07-03 2012-02-29 Actelion Pharmaceuticals Ltd Związki 3-azabicyklo[3.3.0]oktanowe
BRPI0814593A2 (pt) * 2007-07-27 2015-01-20 Actelion Pharmaceuticals Ltd Composto, composição farmacêutica que o contém e uso do composto.
CN107243007A (zh) 2008-10-16 2017-10-13 约翰斯.霍普金斯大学 改善认知功能的方法和组合物
US8191547B2 (en) * 2008-10-23 2012-06-05 S-2Tech Llc Portable solar-heating system having an inflatable solar collector
US20100172979A1 (en) * 2008-12-24 2010-07-08 Zhongshui Yu Controlled-release formulations
US20100159009A1 (en) * 2008-12-24 2010-06-24 Zhongshui Yu Controlled-release formulations
CA2789014C (en) * 2010-02-09 2019-01-15 Michela Gallagher Methods and compositions for improving cognitive function
BR112013020283A2 (pt) * 2011-02-09 2016-07-19 Univ Johns Hopkins "uso de inibidor de proteína de vesícula sináptica 2a (sv2a), valproato, levetiracetam, brivarecetam e seletracetam no tratamento de deficiência cognitiva, bem como composição farmacêutica compreendendo os mesmos"
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神分裂病を処置するための方法および組成物
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
HK1218623A1 (zh) 2013-03-15 2017-03-03 艾吉因生物股份有限公司 用於改善認知功能的方法和組合物
US10925834B2 (en) 2015-05-22 2021-02-23 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam
EP3890833B1 (en) * 2018-12-04 2023-06-07 Metys Pharmaceuticals AG Synergistic compositions comprising (r)-2-(2-oxopyrrolidin-1-yl)butanamide and (s)-2-(2-oxopyrrolidin-1-yl)butanamide in a non-racemic ratio

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0162036A1 (fr) * 1984-05-15 1985-11-21 U C B, S.A. (S)-alpha-éthyl-2-oxo-1-pyrrolidineacétamide
SU1320707A1 (ru) * 1985-01-24 1987-06-30 Ивано-Франковский Институт Нефти И Газа Способ определени износостойкости материалов ма тниковым склерометром
SU1414845A1 (ru) * 1984-03-23 1988-08-07 Всесоюзный Научно-Исследовательский Химико-Фармацевтический Институт Им.С.Орджоникидзе 1-Тиокарбамоилметилпирролидин-2-тион,обладающий ноотропной активностью, и способ его получени
EP0408782A1 (en) * 1989-07-18 1991-01-23 Nauchnoissledovatelski Chimikopharmatzevtichen Institut Antihypoxic agent
US5143912A (en) * 1990-08-21 1992-09-01 Hoffmann-La Roche, Inc. Tricyclic pyridone derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8827389D0 (en) 1988-11-23 1988-12-29 Ucb Sa Process for preparation of(s)alpha-ethyl-2-oxo-1-pyrrolidineacetamide

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1414845A1 (ru) * 1984-03-23 1988-08-07 Всесоюзный Научно-Исследовательский Химико-Фармацевтический Институт Им.С.Орджоникидзе 1-Тиокарбамоилметилпирролидин-2-тион,обладающий ноотропной активностью, и способ его получени
EP0162036A1 (fr) * 1984-05-15 1985-11-21 U C B, S.A. (S)-alpha-éthyl-2-oxo-1-pyrrolidineacétamide
SU1320707A1 (ru) * 1985-01-24 1987-06-30 Ивано-Франковский Институт Нефти И Газа Способ определени износостойкости материалов ма тниковым склерометром
EP0408782A1 (en) * 1989-07-18 1991-01-23 Nauchnoissledovatelski Chimikopharmatzevtichen Institut Antihypoxic agent
US5143912A (en) * 1990-08-21 1992-09-01 Hoffmann-La Roche, Inc. Tricyclic pyridone derivatives

Also Published As

Publication number Publication date
NO943521D0 (no) 1994-09-22
KR950007848A (ko) 1995-04-15
AU7416994A (en) 1995-04-06
TW283642B (enExample) 1996-08-21
AU672334B2 (en) 1996-09-26
JPH07149639A (ja) 1995-06-13
EP0645139B1 (fr) 2000-04-19
NO943521L (no) 1995-03-27
ZA947444B (en) 1995-05-11
NZ264506A (en) 1997-09-22
ES2145818T3 (es) 2000-07-16
HU217124B (hu) 1999-11-29
SG86284A1 (en) 2002-02-19
ATE191849T1 (de) 2000-05-15
EP0645139A1 (fr) 1995-03-29
CA2132509A1 (en) 1995-03-25
JP3688735B2 (ja) 2005-08-31
DE69424009D1 (de) 2000-05-25
DE69424009T2 (de) 2000-09-14
GB9319732D0 (en) 1993-11-10
HUT68299A (en) 1995-06-28
US5447952A (en) 1995-09-05

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