RU2104282C1 - Фосфолипидные производные нуклеозидов и фармацевтическая композиция - Google Patents

Фосфолипидные производные нуклеозидов и фармацевтическая композиция Download PDF

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Publication number
RU2104282C1
RU2104282C1 RU93005146A RU93005146A RU2104282C1 RU 2104282 C1 RU2104282 C1 RU 2104282C1 RU 93005146 A RU93005146 A RU 93005146A RU 93005146 A RU93005146 A RU 93005146A RU 2104282 C1 RU2104282 C1 RU 2104282C1
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RU
Russia
Prior art keywords
phosphoric acid
deoxy
decyloxy
compounds
mercapto
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Application number
RU93005146A
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English (en)
Russian (ru)
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RU93005146A (ru
Inventor
Цильх Харальд
Ляйнерт Херберт
Мертенс Альфред
Херрманн Дитер
Original Assignee
Берингер Маннхайм ГмбХ
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Priority claimed from DE4026265A external-priority patent/DE4026265A1/de
Application filed by Берингер Маннхайм ГмбХ filed Critical Берингер Маннхайм ГмбХ
Publication of RU93005146A publication Critical patent/RU93005146A/ru
Application granted granted Critical
Publication of RU2104282C1 publication Critical patent/RU2104282C1/ru

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • C07H19/10Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • C07H19/20Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
RU93005146A 1990-08-20 1991-08-14 Фосфолипидные производные нуклеозидов и фармацевтическая композиция RU2104282C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4026265A DE4026265A1 (de) 1990-08-20 1990-08-20 Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel
DEP4026265.0 1990-08-20
PCT/EP1991/001541 WO1992003462A1 (de) 1990-08-20 1991-08-14 Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel

Publications (2)

Publication Number Publication Date
RU93005146A RU93005146A (ru) 1996-12-20
RU2104282C1 true RU2104282C1 (ru) 1998-02-10

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ID=6412536

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93005146A RU2104282C1 (ru) 1990-08-20 1991-08-14 Фосфолипидные производные нуклеозидов и фармацевтическая композиция

Country Status (10)

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JP (1) JP3032576B2 (US07026469-20060411-C00007.png)
KR (1) KR970011307B1 (US07026469-20060411-C00007.png)
CZ (1) CZ287942B6 (US07026469-20060411-C00007.png)
HU (1) HU220611B1 (US07026469-20060411-C00007.png)
MX (1) MX9100676A (US07026469-20060411-C00007.png)
NZ (1) NZ239422A (US07026469-20060411-C00007.png)
RO (1) RO115163B1 (US07026469-20060411-C00007.png)
RU (1) RU2104282C1 (US07026469-20060411-C00007.png)
TW (1) TW207544B (US07026469-20060411-C00007.png)
ZA (1) ZA916542B (US07026469-20060411-C00007.png)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004011480A1 (fr) * 2002-07-26 2004-02-05 Zakrytoe Aktsionernoe Obshcestvo 'proizvodstvenno -Kommercheskaya Assotsiatsiya Azt' 5'-choline phosphate 3'-azido 3'-desoxythyimidine

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7026469B2 (en) * 2000-10-19 2006-04-11 Wake Forest University School Of Medicine Compositions and methods of double-targeting virus infections and cancer cells

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J. of Med.Chem.- 34, 1991, N 4, р.1408 - 1414. Chem. and Pharm. Bull. 34, N 1, 1988, p.209 - 217. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004011480A1 (fr) * 2002-07-26 2004-02-05 Zakrytoe Aktsionernoe Obshcestvo 'proizvodstvenno -Kommercheskaya Assotsiatsiya Azt' 5'-choline phosphate 3'-azido 3'-desoxythyimidine

Also Published As

Publication number Publication date
JPH06500543A (ja) 1994-01-20
JP3032576B2 (ja) 2000-04-17
RO115163B1 (ro) 1999-11-30
NZ239422A (en) 1993-09-27
KR930701470A (ko) 1993-06-11
MX9100676A (es) 1992-04-01
CZ18093A3 (en) 1993-06-16
HU9300468D0 (en) 1993-05-28
KR970011307B1 (ko) 1997-07-09
HU220611B1 (hu) 2002-03-28
ZA916542B (en) 1992-05-27
TW207544B (US07026469-20060411-C00007.png) 1993-06-11
HUT62910A (en) 1993-06-28
CZ287942B6 (cs) 2001-03-14

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20090815