RU2021123536A - Сборочные узлы перфузионных биореакторных мешков - Google Patents

Сборочные узлы перфузионных биореакторных мешков Download PDF

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Publication number
RU2021123536A
RU2021123536A RU2021123536A RU2021123536A RU2021123536A RU 2021123536 A RU2021123536 A RU 2021123536A RU 2021123536 A RU2021123536 A RU 2021123536A RU 2021123536 A RU2021123536 A RU 2021123536A RU 2021123536 A RU2021123536 A RU 2021123536A
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Russia
Prior art keywords
port
bioreactor
bag
inlet
bioreactor bag
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RU2021123536A
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English (en)
Russian (ru)
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Паскаль БОШЕН
Крис Дункан ВАЛБУРГ
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Джуно Терапьютикс, Инк.
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Publication of RU2021123536A publication Critical patent/RU2021123536A/ru

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/14—Bags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/40—Manifolds; Distribution pieces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/16—Vibrating; Shaking; Tilting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/24—Recirculation of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
    • C12M3/06—Tissue, human, animal or plant cell, or virus culture apparatus with filtration, ultrafiltration, inverse osmosis or dialysis means

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Clinical Laboratory Science (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Water Supply & Treatment (AREA)
  • Medicinal Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
RU2021123536A 2016-09-12 2017-09-12 Сборочные узлы перфузионных биореакторных мешков RU2021123536A (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662393583P 2016-09-12 2016-09-12
US62/393,583 2016-09-12

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
RU2019110824A Division RU2755725C2 (ru) 2016-09-12 2017-09-12 Сборочные узлы перфузионных биореакторных мешков

Publications (1)

Publication Number Publication Date
RU2021123536A true RU2021123536A (ru) 2022-01-14

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
RU2019110824A RU2755725C2 (ru) 2016-09-12 2017-09-12 Сборочные узлы перфузионных биореакторных мешков
RU2021123536A RU2021123536A (ru) 2016-09-12 2017-09-12 Сборочные узлы перфузионных биореакторных мешков

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RU2019110824A RU2755725C2 (ru) 2016-09-12 2017-09-12 Сборочные узлы перфузионных биореакторных мешков

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Country Link
US (1) US20190211292A1 (enExample)
EP (1) EP3510136A1 (enExample)
JP (1) JP2019526269A (enExample)
KR (1) KR20190045321A (enExample)
CN (1) CN109890952A (enExample)
AU (1) AU2017322752A1 (enExample)
BR (1) BR112019004662A2 (enExample)
CA (1) CA3035829A1 (enExample)
MA (1) MA46194A (enExample)
MX (1) MX2019002765A (enExample)
RU (2) RU2755725C2 (enExample)
WO (1) WO2018049420A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11149244B2 (en) 2018-04-04 2021-10-19 Southwest Research Institute Three-dimensional bioreactor for T-cell activation and expansion for immunotherapy
US11118149B2 (en) * 2018-04-25 2021-09-14 Global Life Sciences Solutions Usa Llc Bioreactor bags
SG11202102986XA (en) 2018-09-24 2021-04-29 Southwest Res Inst Three-dimensional bioreactors
JP7490294B2 (ja) * 2018-11-28 2024-05-27 グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー フィルタを有するバイオリアクタ
KR102716554B1 (ko) * 2019-06-30 2024-10-15 생-고뱅 퍼포먼스 플라스틱스 코포레이션 세포 배양 시스템
KR20220166825A (ko) * 2020-04-10 2022-12-19 사우스웨스트 리서치 인스티튜트 바이러스 벡터 생산을 위한 3차원 생물 반응기
WO2024122708A1 (ko) * 2022-12-07 2024-06-13 주식회사 팡세 생물반응기 시스템 및 이를 이용한 세포 배양방법
WO2024122714A1 (ko) * 2022-12-07 2024-06-13 주식회사 팡세 투석장치 및 이를 포함하는 생물반응기 시스템

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452773A (en) 1982-04-05 1984-06-05 Canadian Patents And Development Limited Magnetic iron-dextran microspheres
US4795698A (en) 1985-10-04 1989-01-03 Immunicon Corporation Magnetic-polymer particles
US5219740A (en) 1987-02-13 1993-06-15 Fred Hutchinson Cancer Research Center Retroviral gene transfer into diploid fibroblasts for gene therapy
WO1990007380A2 (en) 1988-12-28 1990-07-12 Stefan Miltenyi Methods and materials for high gradient magnetic separation of biological materials
CA2066645A1 (en) * 1989-09-14 1991-03-15 Richard A. Knazek Method for the production of in vitro expanded lymphoid cells for use in adoptive immunotherapy
US5200084A (en) 1990-09-26 1993-04-06 Immunicon Corporation Apparatus and methods for magnetic separation
US5827642A (en) 1994-08-31 1998-10-27 Fred Hutchinson Cancer Research Center Rapid expansion method ("REM") for in vitro propagation of T lymphocytes
DE19608753C1 (de) 1996-03-06 1997-06-26 Medigene Gmbh Transduktionssystem und seine Verwendung
US6451995B1 (en) 1996-03-20 2002-09-17 Sloan-Kettering Institute For Cancer Research Single chain FV polynucleotide or peptide constructs of anti-ganglioside GD2 antibodies, cells expressing same and related methods
ATE186235T1 (de) 1996-04-24 1999-11-15 Claude Fell Zelltrennungsvorrichtung für biologische flüssigkeiten wie blut
WO2000014257A1 (en) 1998-09-04 2000-03-16 Sloan-Kettering Institute For Cancer Research Fusion receptors specific for prostate-specific membrane antigen and uses thereof
AU2472400A (en) 1998-10-20 2000-05-08 City Of Hope CD20-specific redirected T cells and their use in cellular immunotherapy of CD20+ malignancies
WO2000038762A1 (en) 1998-12-24 2000-07-06 Biosafe S.A. Blood separation system particularly for concentrating hematopoietic stem cells
WO2001094944A2 (en) 2000-06-02 2001-12-13 Memorial Sloan-Kettering Cancer Center Artificial antigen presenting cells and methods of use thereof
JP5312721B2 (ja) 2000-11-07 2013-10-09 シティ・オブ・ホープ Ｃｄ１９特異的再指向免疫細胞
US6544788B2 (en) * 2001-02-15 2003-04-08 Vijay Singh Disposable perfusion bioreactor for cell culture
US7070995B2 (en) 2001-04-11 2006-07-04 City Of Hope CE7-specific redirected immune cells
US20090257994A1 (en) 2001-04-30 2009-10-15 City Of Hope Chimeric immunoreceptor useful in treating human cancers
US7446190B2 (en) 2002-05-28 2008-11-04 Sloan-Kettering Institute For Cancer Research Nucleic acids encoding chimeric T cell receptors
US20050129671A1 (en) 2003-03-11 2005-06-16 City Of Hope Mammalian antigen-presenting T cells and bi-specific T cells
EP2936984A1 (en) * 2003-05-01 2015-10-28 Medgenics, Inc. Apparatus and method for harvesting a dermal micro-organ
RU45733U1 (ru) * 2004-11-23 2005-05-27 Давыдов Владимир Николаевич Установка для осуществления микробиологических процессов
DK1893253T3 (da) 2005-03-23 2010-08-16 Biosafe Sa Integreret system til opsamling, forarbejdning og transplantation af celledelmængder, omfattende voksenstamceller til regenerativ medicin
JP5840837B2 (ja) 2007-03-30 2016-01-06 メモリアル スローン−ケタリング キャンサー センター 養子移入ｔリンパ球における副刺激リガンドの構成性発現
EP2433713B1 (en) 2007-12-07 2017-07-26 Miltenyi Biotec GmbH Cell processing systems and methods
US8479118B2 (en) 2007-12-10 2013-07-02 Microsoft Corporation Switching search providers within a browser search box
JP5173594B2 (ja) 2008-05-27 2013-04-03 キヤノン株式会社 管理装置、画像形成装置及びそれらの処理方法
US20120329151A1 (en) * 2009-07-06 2012-12-27 F. Hoffmann-La Roche Ag Method of culturing eukaryotic cells
WO2011142670A1 (en) * 2010-05-12 2011-11-17 Xpand Biotechnology B.V. Cell-culture-bag
PH12013501201A1 (en) 2010-12-09 2013-07-29 Univ Pennsylvania Use of chimeric antigen receptor-modified t cells to treat cancer
JP5923529B2 (ja) * 2011-03-18 2016-05-24 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ 細胞培養用可撓性バッグ
MX359513B (es) 2011-03-23 2018-10-01 Hutchinson Fred Cancer Res Metodo y composiciones para inmunoterapia celular.
US8398282B2 (en) 2011-05-12 2013-03-19 Delphi Technologies, Inc. Vehicle front lighting assembly and systems having a variable tint electrowetting element
EP2776451B1 (en) 2011-11-11 2018-07-18 Fred Hutchinson Cancer Research Center Cyclin a1-targeted t-cell immunotherapy for cancer
TWM434774U (en) * 2012-01-19 2012-08-01 Taiwan Advance Bio Pharmaceutical Inc Suspension type closed cell culturing system allowing supply of culture additive
WO2013114845A1 (ja) * 2012-02-01 2013-08-08 東洋製罐グループホールディングス株式会社 細胞培養用キット、及び細胞培養用キットの使用方法
EP2814846B1 (en) 2012-02-13 2020-01-08 Seattle Children's Hospital d/b/a Seattle Children's Research Institute Bispecific chimeric antigen receptors and therapeutic uses thereof
WO2013126726A1 (en) 2012-02-22 2013-08-29 The Trustees Of The University Of Pennsylvania Double transgenic t cells comprising a car and a tcr and their methods of use
EP2639294A1 (fr) * 2012-03-15 2013-09-18 CellProthera Automate et procédé automatisé de culture cellulaire
CN107557334B (zh) 2012-05-03 2021-06-25 弗雷德哈钦森癌症研究中心 增强亲和力的t细胞受体及其制备方法
IL293944A (en) 2012-08-20 2022-08-01 Hutchinson Fred Cancer Res Method and preparations for cellular immunotherapy
KR102198058B1 (ko) 2012-10-02 2021-01-06 메모리얼 슬로안 케터링 캔서 센터 면역치료용 조성물 및 방법
WO2014097442A1 (ja) 2012-12-20 2014-06-26 三菱電機株式会社 車載装置及びプログラム
CN203048949U (zh) * 2012-12-29 2013-07-10 上海乐纯生物技术有限公司 细胞培养袋
US9108442B2 (en) 2013-08-20 2015-08-18 Ricoh Company, Ltd. Image forming apparatus
CN106459917B (zh) 2014-04-23 2021-03-09 朱诺治疗学股份有限公司 分离、培养和遗传工程改造用于过继治疗的免疫细胞群的方法
GB201416362D0 (en) * 2014-07-25 2014-10-29 Ge Healthcare Bio Sciences Ab Method and system for suspension culture
CN204138670U (zh) * 2014-10-09 2015-02-04 沈阳澔源生物科技有限公司 一种细胞培养袋及其支架
CN204198747U (zh) * 2014-10-22 2015-03-11 天津灏洋华科生物科技有限公司 一种便于操作的细胞培养袋
HUE050264T2 (hu) 2014-11-05 2020-11-30 Juno Therapeutics Inc Eljárások transzdukálásra és sejtfeldolgozásra
CN105385597B (zh) * 2015-12-23 2018-10-12 上海吉倍生物技术有限公司 一种细胞培养袋及其应用

Also Published As

Publication number Publication date
KR20190045321A (ko) 2019-05-02
MA46194A (fr) 2019-07-17
NZ752132A (en) 2022-03-25
CA3035829A1 (en) 2018-03-15
BR112019004662A2 (pt) 2019-05-28
RU2019110824A (ru) 2020-10-12
WO2018049420A1 (en) 2018-03-15
EP3510136A1 (en) 2019-07-17
AU2017322752A1 (en) 2019-03-21
CN109890952A (zh) 2019-06-14
MX2019002765A (es) 2019-05-09
JP2019526269A (ja) 2019-09-19
RU2019110824A3 (enExample) 2021-01-22
RU2755725C2 (ru) 2021-09-20
US20190211292A1 (en) 2019-07-11

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