RU2019116422A - Фармацевтическое применение композиции пролонгированного действия, содержащей пирфенидон, для лечения и обращения течения стеатогепатита человека (nafld/nash) - Google Patents
Фармацевтическое применение композиции пролонгированного действия, содержащей пирфенидон, для лечения и обращения течения стеатогепатита человека (nafld/nash) Download PDFInfo
- Publication number
- RU2019116422A RU2019116422A RU2019116422A RU2019116422A RU2019116422A RU 2019116422 A RU2019116422 A RU 2019116422A RU 2019116422 A RU2019116422 A RU 2019116422A RU 2019116422 A RU2019116422 A RU 2019116422A RU 2019116422 A RU2019116422 A RU 2019116422A
- Authority
- RU
- Russia
- Prior art keywords
- treatment
- pirfenidone
- nafld
- nash
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2016014775A MX364040B (es) | 2016-11-11 | 2016-11-11 | Uso farmacéutico de una composición que contiene pirfenidona de liberación prolongada (pfd-lp) para la reversión y tratamiento de la esteatohepatitis humana (nafld/nash). |
| MXMX/A/2016/014775 | 2016-11-11 | ||
| PCT/MX2017/000129 WO2018088886A1 (es) | 2016-11-11 | 2017-11-09 | Uso farmacéutico de una composición que contiene pirfenidona de liberación prolongada (pfd-lp) para la reversión y tratamiento de la esteatohepatitis humana (nafld/nash) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2019116422A true RU2019116422A (ru) | 2020-12-11 |
| RU2019116422A3 RU2019116422A3 (cg-RX-API-DMAC7.html) | 2021-04-09 |
Family
ID=61193005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2019116422A RU2019116422A (ru) | 2016-11-11 | 2017-11-09 | Фармацевтическое применение композиции пролонгированного действия, содержащей пирфенидон, для лечения и обращения течения стеатогепатита человека (nafld/nash) |
Country Status (21)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2007009796A (es) | 2007-08-14 | 2009-02-25 | Cell Therapy And Technology S | Gel conteniendo pirfenidona. |
| MX2011007675A (es) | 2011-07-19 | 2012-07-11 | Cell Therapy And Technology S A De C V | Procedimiento para la fabricacion de una composicion farmaceutica en forma de tabletas de liberacion prolongada conteniendo pirfenidona y su aplicacion en la regresion de la insuficiencia renal cronica, contractura capsular mamaria y fibrosis hepatica humanas. |
| MX346763B (es) | 2012-03-28 | 2017-03-31 | Cell Therapy And Tech S A De C V | Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné. |
| MX356551B (es) | 2012-08-23 | 2018-06-04 | Grupo Medifarma S A De C V Star | Composición antiséptica, antiseborreica y exfoliante para eliminar o prevenir el acné. |
| MX366086B (es) | 2017-08-15 | 2019-06-27 | Cell Therapy And Tech S A De C V | Composicion topica semisolida conteniendo un agente antimicrobiano y pirfenidona para el tratamiento de daños cronicos de la piel. |
| JP2021504479A (ja) * | 2017-11-28 | 2021-02-15 | アイガー・バイオファーマシューティカルズ・インコーポレイテッドＥｉｇｅｒ Ｂｉｏｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | 非アルコール性脂肪性肝炎の処置のための方法および医薬組成物 |
| MX368750B (es) | 2018-08-31 | 2019-10-15 | Cell Therapy And Tech S A De C V | Composiciones farmaceuticas semisolidas de base oleosa conteniendo pirfenidona para su aplicacion en la reparacion tisular. |
| WO2020115774A1 (en) | 2018-12-06 | 2020-06-11 | Cipla Limited | High drug load extended release formulations |
| AU2021365528A1 (en) * | 2020-10-23 | 2023-06-15 | Hq Han | Bifunctional antagonists of tumor necrosis factor-alpha and transforming growth factor-beta and uses thereof |
| CN116159056A (zh) * | 2023-03-09 | 2023-05-26 | 中南大学湘雅医院 | 一种氟非尼酮在制备非酒精性脂肪性肝炎药物中的应用 |
| CN117007806A (zh) * | 2023-09-21 | 2023-11-07 | 中国人民解放军军事科学院军事医学研究院 | 靶向肝巨噬细胞内lxr用于控制慢乙肝进展 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60234812D1 (de) * | 2001-01-29 | 2010-02-04 | Shionogi & Co | Arzneipräparat, das als wirkstoff 5-methyl-1-phenyl-2-(1h)-pyridon enthält |
| WO2005000227A2 (en) * | 2003-06-06 | 2005-01-06 | Intermune, Inc. | Methods of treating tnf-mediated disorders |
| CN100542532C (zh) * | 2004-05-24 | 2009-09-23 | 上海睿星基因技术有限公司 | 吡非尼酮在制备治疗肝损伤坏死和急性肺损伤的药物中的用途 |
| US20110288134A1 (en) * | 2008-10-29 | 2011-11-24 | Pacific Therapeutics Ltd. | Composition and method for treating fibrosis |
| US7635707B1 (en) * | 2008-11-10 | 2009-12-22 | Intermune, Inc. | Pirfenidone treatment for patients with atypical liver function |
| CN101972236A (zh) * | 2010-10-13 | 2011-02-16 | 北京诚创康韵医药科技有限公司 | 一种含吡非尼酮的缓释制剂 |
| MX2011007675A (es) * | 2011-07-19 | 2012-07-11 | Cell Therapy And Technology S A De C V | Procedimiento para la fabricacion de una composicion farmaceutica en forma de tabletas de liberacion prolongada conteniendo pirfenidona y su aplicacion en la regresion de la insuficiencia renal cronica, contractura capsular mamaria y fibrosis hepatica humanas. |
| CN102488660A (zh) * | 2011-12-15 | 2012-06-13 | 西安天一秦昆制药有限责任公司 | 一种含吡非尼酮的缓释微丸 |
| CN103550242B (zh) * | 2013-11-22 | 2015-07-15 | 四川国康药业有限公司 | 一种治疗肝纤维化的药物组合物及其制备方法 |
-
2016
- 2016-11-11 MX MX2016014775A patent/MX364040B/es active IP Right Grant
-
2017
- 2017-06-16 JO JOP/2019/0102A patent/JOP20190102A1/ar unknown
- 2017-11-09 CN CN202211265065.XA patent/CN115969802A/zh active Pending
- 2017-11-09 KR KR1020247015017A patent/KR20240065330A/ko not_active Ceased
- 2017-11-09 KR KR1020197014274A patent/KR20190084056A/ko not_active Ceased
- 2017-11-09 UY UY0001037478A patent/UY37478A/es not_active Application Discontinuation
- 2017-11-09 PE PE2019000946A patent/PE20191149A1/es unknown
- 2017-11-09 MA MA45754A patent/MA45754A1/fr unknown
- 2017-11-09 CA CA3043300A patent/CA3043300A1/en active Pending
- 2017-11-09 JP JP2019547064A patent/JP2019535822A/ja active Pending
- 2017-11-09 AU AU2017358367A patent/AU2017358367B2/en active Active
- 2017-11-09 WO PCT/MX2017/000129 patent/WO2018088886A1/es not_active Ceased
- 2017-11-09 RU RU2019116422A patent/RU2019116422A/ru unknown
- 2017-11-09 US US16/348,189 patent/US20190262325A1/en not_active Abandoned
- 2017-11-09 EP EP17840578.3A patent/EP3539537B1/en active Active
- 2017-11-09 CN CN201780076430.3A patent/CN110248646A/zh active Pending
- 2017-11-10 AR ARP170103142A patent/AR110057A1/es unknown
-
2019
- 2019-05-08 IL IL266519A patent/IL266519A/en unknown
- 2019-05-08 EC ECSENADI201931851A patent/ECSP19031851A/es unknown
- 2019-05-09 CL CL2019001280A patent/CL2019001280A1/es unknown
- 2019-05-10 PH PH12019501047A patent/PH12019501047A1/en unknown
- 2019-05-10 CO CONC2019/0004799A patent/CO2019004799A2/es unknown
- 2019-05-14 ZA ZA2019/03012A patent/ZA201903012B/en unknown
-
2022
- 2022-09-26 JP JP2022152261A patent/JP2022173344A/ja active Pending
- 2022-11-02 US US18/051,937 patent/US20230181550A1/en not_active Abandoned
-
2024
- 2024-02-07 AU AU2024200737A patent/AU2024200737A1/en not_active Abandoned
- 2024-12-02 US US18/965,593 patent/US20250325530A1/en active Pending
-
2026
- 2026-01-16 AU AU2026200298A patent/AU2026200298A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20190262325A1 (en) | 2019-08-29 |
| KR20190084056A (ko) | 2019-07-15 |
| MX364040B (es) | 2019-04-11 |
| IL266519A (en) | 2019-07-31 |
| JP2019535822A (ja) | 2019-12-12 |
| US20250325530A1 (en) | 2025-10-23 |
| PE20191149A1 (es) | 2019-09-02 |
| AU2024200737A1 (en) | 2024-02-22 |
| JP2022173344A (ja) | 2022-11-18 |
| CN115969802A (zh) | 2023-04-18 |
| EP3539537B1 (en) | 2026-07-15 |
| EP3539537A1 (en) | 2019-09-18 |
| CO2019004799A2 (es) | 2019-07-31 |
| CA3043300A1 (en) | 2018-05-17 |
| RU2019116422A3 (cg-RX-API-DMAC7.html) | 2021-04-09 |
| AR110057A1 (es) | 2019-02-20 |
| MA45754A1 (fr) | 2019-12-31 |
| AU2017358367B2 (en) | 2023-11-09 |
| CN110248646A (zh) | 2019-09-17 |
| MX2016014775A (es) | 2018-05-10 |
| US20230181550A1 (en) | 2023-06-15 |
| CL2019001280A1 (es) | 2019-07-19 |
| ECSP19031851A (es) | 2019-06-30 |
| WO2018088886A1 (es) | 2018-05-17 |
| AU2017358367A1 (en) | 2019-05-30 |
| PH12019501047A1 (en) | 2019-12-11 |
| ZA201903012B (en) | 2020-09-30 |
| KR20240065330A (ko) | 2024-05-14 |
| UY37478A (es) | 2018-05-31 |
| AU2026200298A1 (en) | 2026-02-05 |
| JOP20190102A1 (ar) | 2019-05-06 |
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