RU2018144897A - Композиции пробиотиков и пищеварительных ферментов и способы их получения и применения - Google Patents

Композиции пробиотиков и пищеварительных ферментов и способы их получения и применения Download PDF

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RU2018144897A
RU2018144897A RU2018144897A RU2018144897A RU2018144897A RU 2018144897 A RU2018144897 A RU 2018144897A RU 2018144897 A RU2018144897 A RU 2018144897A RU 2018144897 A RU2018144897 A RU 2018144897A RU 2018144897 A RU2018144897 A RU 2018144897A
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lactobacillus
billion cfu
mixture
probiotics
pharmaceutical composition
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RU2018144897A
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Russian (ru)
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RU2018144897A3 (cg-RX-API-DMAC10.html
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Ким ШЕФЕР
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Ким ШЕФЕР
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Publication of RU2018144897A3 publication Critical patent/RU2018144897A3/ru
Publication of RU2018144897A publication Critical patent/RU2018144897A/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/54—Mixtures of enzymes or proenzymes covered by more than a single one of groups A61K38/44 - A61K38/46 or A61K38/51 - A61K38/53
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01003—Triacylglycerol lipase (3.1.1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01001—Alpha-amylase (3.2.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01003—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01004—Cellulase (3.2.1.4), i.e. endo-1,4-beta-glucanase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01008—Endo-1,4-beta-xylanase (3.2.1.8)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01026—Beta-fructofuranosidase (3.2.1.26), i.e. invertase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01108—Lactase (3.2.1.108)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/22—Cysteine endopeptidases (3.4.22)
    • C12Y304/22002—Papain (3.4.22.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/22—Cysteine endopeptidases (3.4.22)
    • C12Y304/22032—Stem bromelain (3.4.22.32)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Enzymes And Modification Thereof (AREA)
RU2018144897A 2016-05-24 2016-05-24 Композиции пробиотиков и пищеварительных ферментов и способы их получения и применения RU2018144897A (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2016/033976 WO2017204788A1 (en) 2016-05-24 2016-05-24 Composition of probiotics and digestive enzymes and method of preparing and using the same

Publications (2)

Publication Number Publication Date
RU2018144897A3 RU2018144897A3 (cg-RX-API-DMAC10.html) 2020-06-25
RU2018144897A true RU2018144897A (ru) 2020-06-25

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Country Status (12)

Country Link
US (1) US20200323929A1 (cg-RX-API-DMAC10.html)
EP (1) EP3463404A4 (cg-RX-API-DMAC10.html)
JP (1) JP2019516775A (cg-RX-API-DMAC10.html)
KR (1) KR102380198B1 (cg-RX-API-DMAC10.html)
CN (1) CN109451727A (cg-RX-API-DMAC10.html)
AU (1) AU2016408376B2 (cg-RX-API-DMAC10.html)
BR (1) BR112018074355A2 (cg-RX-API-DMAC10.html)
CA (1) CA3025512A1 (cg-RX-API-DMAC10.html)
IL (1) IL263238A (cg-RX-API-DMAC10.html)
MX (1) MX2018014500A (cg-RX-API-DMAC10.html)
RU (1) RU2018144897A (cg-RX-API-DMAC10.html)
WO (1) WO2017204788A1 (cg-RX-API-DMAC10.html)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3055915A1 (en) * 2017-03-10 2018-09-13 Biohm Health Llc Compositions and methods for disrupting biofilms of pathogenic bacteria or fungi
WO2019169179A1 (en) * 2018-02-28 2019-09-06 Shafer Kim Augmenting efficacy of cancer therapies using probiotic based compositions
WO2019173763A1 (en) * 2018-03-09 2019-09-12 Biohm Health Llc Compositions for use in balancing microbiome
CN109528776A (zh) * 2018-06-08 2019-03-29 广东益可维健康科技有限公司 一种预防治疗口腔疾病的复合益生菌含片及其制备方法
CN109566935A (zh) * 2018-12-06 2019-04-05 张秋环 综合益生菌复合粉固体饮料的制备方法
TWI740101B (zh) * 2019-02-12 2021-09-21 大江生醫股份有限公司 降膽固醇之益生菌株的用途
KR102119133B1 (ko) 2019-05-02 2020-06-26 선정완 유산균 분말 및 노니 분말을 포함하는 프로바이오틱스 조성물
CN114341363B (zh) * 2019-08-30 2026-04-24 Hem制药股份有限公司 使用pmas方法的个体化定制型肠道环境改善物质筛选方法
KR102124474B1 (ko) * 2019-08-30 2020-06-19 주식회사 에이치이엠 Pmas방법을 이용한 개인 맞춤형 장내 환경 개선 물질 스크리닝 방법
WO2021066586A1 (ko) * 2019-10-02 2021-04-08 한국생명공학연구원 비만의 예방, 치료 또는 개선용 조성물
CN111213885A (zh) * 2020-01-20 2020-06-02 齐海心 一种具有调节血脂功效的益生菌组合物及其制备方法与应用
TW202203950A (zh) * 2020-03-30 2022-02-01 香港商香港微生物菌群創新中心有限公司 微生物在調節體重和膽固醇水準中的用途
CN111558033A (zh) * 2020-05-14 2020-08-21 广州中昱医学生物科技有限公司 一种口腔清洁组合物及其应用
CN112021575A (zh) * 2020-09-17 2020-12-04 泉州亚林新材料科技有限公司 一种益生菌组合物及其制备方法
EP4280884A1 (en) * 2021-01-19 2023-11-29 ATR Thrive, LLC Compositions of milk and enzymes for adult nutrition
CN113244408A (zh) * 2021-06-02 2021-08-13 河北源民生物科技有限公司 一种适用于肠胃的益生菌组合物
JP2023159522A (ja) * 2022-04-20 2023-11-01 国立大学法人 和歌山大学 短鎖脂肪酸産生促進用組成物
CN115025132B (zh) * 2022-06-09 2024-01-30 康永波 一种合生元组合物及其制备方法和应用
CN116042486B (zh) * 2023-02-22 2024-11-08 高邮市人民医院 一种用于治疗动脉粥样硬化的复合菌制剂
WO2025076281A1 (en) * 2023-10-06 2025-04-10 Biohm Health Inc. Microbiome modulating formula for menopausal-aged women

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7432097B2 (en) * 1997-08-13 2008-10-07 Verenium Corporation Phytases, nucleic acids encoding them and methods of making and using them
US6436451B1 (en) * 1999-03-26 2002-08-20 Eggland's Best, Inc. Method of reducing cholesterol in chicken eggs
US6368617B1 (en) * 2001-05-15 2002-04-09 Reliv' International, Inc. Dietary supplement
US20040071685A1 (en) * 2002-10-09 2004-04-15 Devin Houston Compositions and methods for increasing the bioavailability of plant polyphenols
GB2465814B (en) * 2008-06-19 2011-10-26 Tarig Sayed Mustafa Arbab Method,composition and device for the treatment of enzymes and saccharides disorders
US8257694B2 (en) * 2009-05-14 2012-09-04 Product Partners, Llc Nutritional compositions for reducing oxidative damage
RU2573907C2 (ru) * 2010-04-26 2016-01-27 Новозимс А/С Гранула для применения в порошковых моющих средствах и композиция гранулированного моющего средства
US9301983B2 (en) * 2014-03-07 2016-04-05 Genmont Biotech Inc. Composition and method of Lactobacillus reuteri GMNL-89 in treating type 2 diabetes
WO2015172191A1 (en) * 2014-05-12 2015-11-19 Medlab Ip Pty Ltd Probiotic compositions and uses thereof for treatment of obesity-related disorders
AU2015100952A4 (en) * 2014-07-17 2015-08-20 Pharm-A-Care Laboratories Pty Ltd Probiotic- and enzyme-containing compositions and uses thereof

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Publication number Publication date
RU2018144897A3 (cg-RX-API-DMAC10.html) 2020-06-25
CN109451727A (zh) 2019-03-08
AU2016408376A1 (en) 2019-01-17
BR112018074355A2 (pt) 2019-03-06
US20200323929A1 (en) 2020-10-15
KR102380198B1 (ko) 2022-03-29
CA3025512A1 (en) 2017-11-30
EP3463404A4 (en) 2020-03-11
JP2019516775A (ja) 2019-06-20
AU2016408376B2 (en) 2020-10-22
KR20190015718A (ko) 2019-02-14
EP3463404A1 (en) 2019-04-10
IL263238A (en) 2018-12-31
WO2017204788A1 (en) 2017-11-30
MX2018014500A (es) 2019-04-15

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