RU2017114341A3 - - Google Patents
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- Publication number
- RU2017114341A3 RU2017114341A3 RU2017114341A RU2017114341A RU2017114341A3 RU 2017114341 A3 RU2017114341 A3 RU 2017114341A3 RU 2017114341 A RU2017114341 A RU 2017114341A RU 2017114341 A RU2017114341 A RU 2017114341A RU 2017114341 A3 RU2017114341 A3 RU 2017114341A3
- Authority
- RU
- Russia
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462057541P | 2014-09-30 | 2014-09-30 | |
| US62/057,541 | 2014-09-30 | ||
| US201562172511P | 2015-06-08 | 2015-06-08 | |
| US62/172,511 | 2015-06-08 | ||
| PCT/EP2015/072324 WO2016050721A1 (en) | 2014-09-30 | 2015-09-29 | Pd-l1 antibodies binding canine pd-l1 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2020117210A Division RU2020117210A (ru) | 2014-09-30 | 2015-09-29 | Антитела к pd-l1, связывающие pd-l1 собаки |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2017114341A RU2017114341A (ru) | 2018-11-09 |
| RU2017114341A3 true RU2017114341A3 (ru) | 2019-07-17 |
| RU2722562C2 RU2722562C2 (ru) | 2020-06-01 |
Family
ID=54207505
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2017114341A RU2722562C2 (ru) | 2014-09-30 | 2015-09-29 | Антитела к pd-l1, связывающие pd-l1 собаки |
| RU2020117210A RU2020117210A (ru) | 2014-09-30 | 2015-09-29 | Антитела к pd-l1, связывающие pd-l1 собаки |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2020117210A RU2020117210A (ru) | 2014-09-30 | 2015-09-29 | Антитела к pd-l1, связывающие pd-l1 собаки |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US10550194B2 (ru) |
| EP (1) | EP3201230B1 (ru) |
| JP (1) | JP6797111B2 (ru) |
| CN (2) | CN107074952B (ru) |
| AU (2) | AU2015326996B2 (ru) |
| BR (1) | BR112017006203A2 (ru) |
| CA (1) | CA2961987A1 (ru) |
| DK (1) | DK3201230T3 (ru) |
| ES (1) | ES2853823T3 (ru) |
| RU (2) | RU2722562C2 (ru) |
| WO (1) | WO2016050721A1 (ru) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA109108C2 (ru) | 2008-12-09 | 2015-07-27 | Дженентек, Інк. | Антитело к pd-l1 и его применение для усиления функции t-клеток |
| DK3083694T3 (da) * | 2013-12-20 | 2024-01-29 | Intervet Int Bv | Caniniserede, murine anti-canin-pd-1-antistoffer |
| MX2017011644A (es) | 2015-03-13 | 2017-12-04 | Cytomx Therapeutics Inc | Anticuerpos anti-pdl1, anticuerpos anti-pdl1 activables y metodos de uso de los mismos. |
| EP3954710A3 (en) | 2015-04-02 | 2022-07-20 | Intervet International B.V. | Antibodies to canine interleukin-4 receptor alpha |
| US11091556B2 (en) | 2015-12-18 | 2021-08-17 | Intervet Inc. | Caninized human antibodies to human IL-4R alpha |
| CN109475603B (zh) | 2016-06-20 | 2023-06-13 | 科马布有限公司 | 抗pd-l1抗体 |
| WO2018009921A1 (en) * | 2016-07-08 | 2018-01-11 | AskGene Pharma, Inc. | Fusion protein comprising leptin and methods for producing and using the same |
| CN107686520B (zh) * | 2016-08-04 | 2023-01-03 | 信达生物制药(苏州)有限公司 | 抗pd-l1纳米抗体及其应用 |
| CA3033896A1 (en) * | 2016-08-15 | 2018-02-22 | National University Corporation Hokkaido University | Anti-pd-l1 antibody |
| CN110114369A (zh) * | 2016-10-17 | 2019-08-09 | 威隆股份公司 | 修饰的抗体恒定区 |
| AU2018242880B2 (en) | 2017-03-27 | 2024-05-16 | Fuso Pharmaceutical Industries, Ltd. | Anti-PD-L1 antibody for detecting PD-L1 |
| BR112019025188A2 (pt) | 2017-06-01 | 2020-06-23 | Cytomx Therapeutics, Inc. | Anticorpos anti-pdl1 ativáveis e métodos de uso dos mesmos |
| US20190100587A1 (en) * | 2017-10-02 | 2019-04-04 | Covagen Ag | IgG1 Fc MUTANTS WITH ABLATED EFFECTOR FUNCTIONS |
| CN111344305B (zh) * | 2017-11-27 | 2022-09-16 | 山东博安生物技术股份有限公司 | 抗pd-l1的抗体及其用途 |
| KR20210110563A (ko) * | 2018-10-18 | 2021-09-08 | 킨드레드 바이오사이언시스, 인코포레이티드 | 수의학적 용도를 위한 신생아 fc 수용체(fcrn)에 변경된 결합을 갖는 fc 변이체 |
| CN109452229B (zh) * | 2018-11-19 | 2021-10-22 | 百奥赛图(北京)医药科技股份有限公司 | 狗源化pd-1基因改造动物模型的制备方法及应用 |
| EP3902564A4 (en) * | 2018-12-27 | 2022-09-28 | Kindred Biosciences, Inc. | IGG-FC VARIANTS FOR USE IN VETERINARY MEDICINE |
| CN112920276B (zh) * | 2019-06-03 | 2021-11-12 | 北京希诺谷生物科技有限公司 | 抗犬pd-1抗体及其制备方法 |
| US20220251209A1 (en) | 2019-07-15 | 2022-08-11 | Intervet Inc. | Caninized antibodies to human ctla-4 |
| CN114174337A (zh) * | 2019-07-15 | 2022-03-11 | 英特维特国际股份有限公司 | 针对犬ctla-4的犬源化抗体 |
| CN110590959B (zh) * | 2019-09-19 | 2021-01-05 | 北京伟杰信生物科技有限公司 | 重组犬pd-1融合蛋白及其制备方法与应用 |
| WO2021225954A1 (en) * | 2020-05-04 | 2021-11-11 | The Regents Of The University Of California | Inhibiting anti-enpp1 antibodies |
| WO2023012486A1 (en) * | 2021-08-06 | 2023-02-09 | Petmedix Ltd | Antibody fc variants |
| CN117343185B (zh) * | 2023-12-06 | 2024-03-01 | 北京伟杰信生物科技有限公司 | 一种抗犬pd-1抗体及其用途 |
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| PT1068241E (pt) | 1998-04-02 | 2007-11-19 | Genentech Inc | Variantes de anticorpos e respectivos fragmentos |
| US6703360B2 (en) | 2000-04-07 | 2004-03-09 | Heska Corporation | Compositions and methods related to canine IgG and canine IL-13 receptors |
| ATE481985T1 (de) | 2002-07-03 | 2010-10-15 | Ono Pharmaceutical Co | Immunpotenzierende zusammensetzungen |
| TW200902555A (en) | 2005-01-03 | 2009-01-16 | Hoffmann La Roche | Antibodies against IL-13 receptor alpha 1 and uses thereof |
| SI2439273T1 (sl) | 2005-05-09 | 2019-05-31 | Ono Pharmaceutical Co., Ltd. | Človeška monoklonska protitelesa za programirano smrt 1 (PD-1) in postopki za zdravljenje raka z uporabo protiteles proti PD-1 samostojno ali v kombinaciji z ostalimi imunoterapevtiki |
| CN101248089A (zh) * | 2005-07-01 | 2008-08-20 | 米德列斯公司 | 抗程序性死亡配体1（pd-l1）的人单克隆抗体 |
| KR101586617B1 (ko) | 2007-06-18 | 2016-01-20 | 머크 샤프 앤 도메 비.브이. | 사람 프로그램된 사멸 수용체 ｐｄ-1에 대한 항체 |
| WO2009048560A1 (en) * | 2007-10-08 | 2009-04-16 | Intrexon Corporation | Engineered dendritic cells and uses for the treatment of cancer |
| EP2725037A1 (en) | 2008-09-04 | 2014-04-30 | Vet Therapeutics, Inc. | Monoclonal antibodies binding canine CD20 |
| AU2013204861B2 (en) * | 2008-09-26 | 2016-05-12 | Dana-Farber Cancer Institute, Inc. | Human anti-PD-1, PD-L1, and PD-L2 antibodies and uses therefor |
| SI2342226T1 (sl) | 2008-09-26 | 2016-11-30 | Dana-Farber Cancer Institute Inc. | Humana protitelesa proti PD-1, PD-L1 in PD-L2 in njihove uporabe |
| EP2411050A4 (en) | 2009-03-25 | 2013-07-17 | Vet Therapeutics Inc | ANTIBODY REGIONS WITH A CONSTANT DOMAIN AND THEIR USE |
| WO2010117448A2 (en) | 2009-04-05 | 2010-10-14 | Provenance Biopharmaceuticals Corp. | Chimeric immunocytokines and methods of use thereof |
| US20130017199A1 (en) * | 2009-11-24 | 2013-01-17 | AMPLIMMUNE ,Inc. a corporation | Simultaneous inhibition of pd-l1/pd-l2 |
| US9616120B2 (en) | 2010-03-04 | 2017-04-11 | Vet Therapeutics, Inc. | Monoclonal antibodies directed to CD20 |
| CA2791866A1 (en) | 2010-03-04 | 2011-09-09 | Vet Therapeutics, Inc. | Monoclonal antibodies directed to cd52 |
| GB201114858D0 (en) | 2011-08-29 | 2011-10-12 | Nvip Pty Ltd | Anti-nerve growth factor antibodies and methods of using the same |
| ES2704007T3 (es) | 2011-05-06 | 2019-03-13 | Nexvet Australia Pty Ltd | Anticuerpos anti-factor de crecimiento nervioso y procedimientos de preparación y uso de los mismos |
| US9328164B2 (en) | 2011-05-06 | 2016-05-03 | Nvip Pty Ltd | Anti-nerve growth factor antibodies and methods of preparing and using the same |
| GB2528401A (en) | 2011-05-06 | 2016-01-20 | Nvip Pty Ltd | Anti-nerve growth factor antibodies and methods of preparing and using the same |
| CA2835094C (en) | 2011-05-06 | 2020-12-22 | David Gearing | Anti-nerve growth factor antibodies and methods of preparing and using the same |
| KR20140063752A (ko) | 2011-08-30 | 2014-05-27 | 엔브이아이피 피티와이 리미티드 | 견화(犬化) 종양 괴사 인자 항체 및 그의 이용방법 |
| BR112014010008A2 (pt) | 2011-10-26 | 2018-09-04 | Novartis Ag | anticorpos monoclonais, seus usos e ácidos nucleicos |
| DK2785375T3 (da) * | 2011-11-28 | 2020-10-12 | Merck Patent Gmbh | Anti-pd-l1-antistoffer og anvendelser deraf |
| DK3083694T3 (da) * | 2013-12-20 | 2024-01-29 | Intervet Int Bv | Caniniserede, murine anti-canin-pd-1-antistoffer |
| WO2016006241A1 (ja) | 2014-07-09 | 2016-01-14 | 日本全薬工業株式会社 | 抗イヌｐｄ－１抗体又は抗イヌｐｄ－ｌ１抗体 |
| JP6945444B2 (ja) * | 2014-08-08 | 2021-10-06 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 高親和性ｐｄ−１薬剤とその使用方法 |
| US20160129097A1 (en) * | 2014-11-06 | 2016-05-12 | Jeremy Delk | Method of processing a veterinary tumor vaccine and a veterinary tumor vaccine processing kit |
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2015
- 2015-09-29 EP EP15771582.2A patent/EP3201230B1/en active Active
- 2015-09-29 RU RU2017114341A patent/RU2722562C2/ru active
- 2015-09-29 JP JP2017516842A patent/JP6797111B2/ja active Active
- 2015-09-29 CN CN201580052709.9A patent/CN107074952B/zh active Active
- 2015-09-29 CA CA2961987A patent/CA2961987A1/en active Pending
- 2015-09-29 RU RU2020117210A patent/RU2020117210A/ru unknown
- 2015-09-29 BR BR112017006203-8A patent/BR112017006203A2/pt active Search and Examination
- 2015-09-29 DK DK15771582.2T patent/DK3201230T3/da active
- 2015-09-29 WO PCT/EP2015/072324 patent/WO2016050721A1/en active Application Filing
- 2015-09-29 AU AU2015326996A patent/AU2015326996B2/en active Active
- 2015-09-29 US US15/514,920 patent/US10550194B2/en active Active
- 2015-09-29 ES ES15771582T patent/ES2853823T3/es active Active
- 2015-09-29 CN CN202110355046.5A patent/CN112851816B/zh active Active
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2019
- 2019-12-18 US US16/718,729 patent/US11447561B2/en active Active
-
2021
- 2021-08-18 AU AU2021218094A patent/AU2021218094B2/en active Active
-
2022
- 2022-08-15 US US17/819,745 patent/US20220389114A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP6797111B2 (ja) | 2020-12-09 |
| US20220389114A1 (en) | 2022-12-08 |
| RU2017114341A (ru) | 2018-11-09 |
| WO2016050721A1 (en) | 2016-04-07 |
| RU2020117210A (ru) | 2020-06-16 |
| CA2961987A1 (en) | 2016-04-07 |
| US10550194B2 (en) | 2020-02-04 |
| AU2015326996A1 (en) | 2017-03-23 |
| RU2722562C2 (ru) | 2020-06-01 |
| DK3201230T3 (da) | 2021-02-15 |
| JP2017534267A (ja) | 2017-11-24 |
| CN112851816B (zh) | 2024-03-08 |
| AU2021218094A1 (en) | 2021-09-09 |
| BR112017006203A2 (pt) | 2018-05-02 |
| CN107074952B (zh) | 2021-04-09 |
| US20200109212A1 (en) | 2020-04-09 |
| CN107074952A (zh) | 2017-08-18 |
| CN112851816A (zh) | 2021-05-28 |
| US11447561B2 (en) | 2022-09-20 |
| AU2015326996B2 (en) | 2021-05-20 |
| AU2021218094B2 (en) | 2023-04-20 |
| ES2853823T3 (es) | 2021-09-17 |
| EP3201230B1 (en) | 2020-12-23 |
| US20180237535A1 (en) | 2018-08-23 |
| EP3201230A1 (en) | 2017-08-09 |