RU2016152151A3 - - Google Patents

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Publication number
RU2016152151A3
RU2016152151A3 RU2016152151A RU2016152151A RU2016152151A3 RU 2016152151 A3 RU2016152151 A3 RU 2016152151A3 RU 2016152151 A RU2016152151 A RU 2016152151A RU 2016152151 A RU2016152151 A RU 2016152151A RU 2016152151 A3 RU2016152151 A3 RU 2016152151A3
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RU
Russia
Application number
RU2016152151A
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RU2016152151A (ru
RU2714154C2 (ru
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Publication of RU2016152151A publication Critical patent/RU2016152151A/ru
Publication of RU2016152151A3 publication Critical patent/RU2016152151A3/ru
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Publication of RU2714154C2 publication Critical patent/RU2714154C2/ru

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • A61K38/37Factors VIII
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/06Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
RU2016152151A 2014-06-06 2015-06-08 Препарат, содержащий фактор viii и пептиды фактора фон виллебранда RU2714154C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14171579.7 2014-06-06
EP14171579 2014-06-06
PCT/EP2015/062730 WO2015185758A2 (en) 2014-06-06 2015-06-08 Preparation comprising factor viii and von willebrand factor peptides

Publications (3)

Publication Number Publication Date
RU2016152151A RU2016152151A (ru) 2018-07-10
RU2016152151A3 true RU2016152151A3 (ru) 2019-02-06
RU2714154C2 RU2714154C2 (ru) 2020-02-12

Family

ID=50884302

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2016152151A RU2714154C2 (ru) 2014-06-06 2015-06-08 Препарат, содержащий фактор viii и пептиды фактора фон виллебранда

Country Status (13)

Country Link
US (1) US10251940B2 (ru)
EP (2) EP3360895B1 (ru)
JP (1) JP6605593B2 (ru)
KR (1) KR20170010895A (ru)
CN (1) CN106414492B (ru)
AU (1) AU2015270394B2 (ru)
BR (1) BR112016026842A2 (ru)
CA (1) CA2949323A1 (ru)
DK (2) DK3152230T3 (ru)
ES (2) ES2747815T3 (ru)
IL (1) IL249294A0 (ru)
RU (1) RU2714154C2 (ru)
WO (1) WO2015185758A2 (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6851381B6 (ja) * 2016-01-07 2021-04-21 ツェー・エス・エル・ベーリング・レングナウ・アクチエンゲゼルシャフト 変異切断型フォンウィルブランド因子
JP2019522962A (ja) 2016-05-20 2019-08-22 オクタファルマ アクチェン ゲゼルシャフト 改善された薬物動態を有する、グリコシル化vwf融合タンパク質
SG10201912768YA (en) 2016-11-11 2020-02-27 CSL Behring Lengnau AG Truncated von willebrand factor polypeptides for extravascular administration in the treatment or prophylaxis of a blood coagulation disorder
KR20200018690A (ko) 2017-06-22 2020-02-19 체에스엘 베링 렝나우 아게 절단된 vwf에 의한 fviii 면역원성의 조절
SG11202010767SA (en) 2018-05-18 2020-11-27 Bioverativ Therapeutics Inc Methods of treating hemophilia a
KR20220029733A (ko) 2019-07-04 2022-03-08 체에스엘 베링 렝나우 아게 응고 인자 viii의 시험관내 안정성을 증가시키기 위한 절단된 폰 빌레브란트 인자 (vwf)
WO2021032646A1 (en) 2019-08-16 2021-02-25 Octapharma Ag Stabilizing buffer for factor viii and vwf

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE504074C2 (sv) 1993-07-05 1996-11-04 Pharmacia Ab Proteinberedning för subkutan, intramuskulär eller intradermal administrering
IL113010A0 (en) 1994-03-31 1995-10-31 Pharmacia Ab Pharmaceutical formulation comprising factor VIII or factor ix with an activity of at least 200 IU/ml and an enhancer for improved subcutaneous intramuscular or intradermal administration
WO2008151817A1 (en) 2007-06-13 2008-12-18 Csl Behring Gmbh Use of vwf stabilized fviii preparations and of vwf preparations without fviii for extravascular administration in the therapy and prophylactic treatment of bleeding disorders
ES2298096B1 (es) * 2008-01-08 2009-01-01 Grifols, S.A. Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacionde los mismos.
MX2011001624A (es) 2008-08-21 2011-03-28 Octapharma Ag Factor viii y ix humano producido en forma recombinante.
EP2467399B2 (en) * 2009-08-20 2023-02-01 Baxalta Incorporated Purification of vWF for increased removal of non-lipid enveloped viruses
WO2011020866A2 (en) 2009-08-20 2011-02-24 Csl Behring Gmbh Albumin fused coagulation factors for non-intravenous administration in the therapy and prophylactic treatment of bleeding disorders
EP2768522B1 (en) 2011-10-18 2016-07-27 CSL Behring GmbH Use of sulfated glycosaminoglycans for improving the bioavailability of factor viii
CN104411323A (zh) * 2012-04-24 2015-03-11 诺和诺德A/S(股份有限公司) 适用于治疗血友病的药物组合物
EP2841451A1 (en) * 2012-04-24 2015-03-04 Novo Nordisk A/S Compounds suitable for treatment of haemophilia

Also Published As

Publication number Publication date
CN106414492A (zh) 2017-02-15
EP3360895A2 (en) 2018-08-15
JP2017518376A (ja) 2017-07-06
US10251940B2 (en) 2019-04-09
CA2949323A1 (en) 2015-12-10
JP6605593B2 (ja) 2019-11-13
RU2016152151A (ru) 2018-07-10
WO2015185758A3 (en) 2016-02-11
DK3360895T3 (da) 2021-11-15
ES2895798T3 (es) 2022-02-22
DK3152230T3 (da) 2019-11-11
EP3360895B1 (en) 2021-08-11
WO2015185758A2 (en) 2015-12-10
EP3152230A2 (en) 2017-04-12
EP3360895A3 (en) 2018-10-17
AU2015270394A1 (en) 2016-11-24
US20180185455A1 (en) 2018-07-05
EP3152230B1 (en) 2019-08-07
AU2015270394B2 (en) 2017-12-21
RU2714154C2 (ru) 2020-02-12
BR112016026842A2 (pt) 2017-12-12
ES2747815T3 (es) 2020-03-11
IL249294A0 (en) 2017-02-28
CN106414492B (zh) 2021-07-06
KR20170010895A (ko) 2017-02-01

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