RU2015111229A3 - - Google Patents
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- Publication number
- RU2015111229A3 RU2015111229A3 RU2015111229A RU2015111229A RU2015111229A3 RU 2015111229 A3 RU2015111229 A3 RU 2015111229A3 RU 2015111229 A RU2015111229 A RU 2015111229A RU 2015111229 A RU2015111229 A RU 2015111229A RU 2015111229 A3 RU2015111229 A3 RU 2015111229A3
- Authority
- RU
- Russia
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Transplantation (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08168865 | 2008-11-11 | ||
| EP08168865.7 | 2008-11-11 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2011123371/04A Division RU2549899C2 (ru) | 2008-11-11 | 2009-11-10 | Кристаллические формы гидрохлорида финголимода |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2015111229A RU2015111229A (ru) | 2015-11-20 |
| RU2015111229A3 true RU2015111229A3 (https=) | 2018-11-08 |
Family
ID=40521487
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2011123371/04A RU2549899C2 (ru) | 2008-11-11 | 2009-11-10 | Кристаллические формы гидрохлорида финголимода |
| RU2015111229/04A RU2015111229A (ru) | 2008-11-11 | 2009-11-10 | Кристаллические формы гидрохлорида финголимода |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2011123371/04A RU2549899C2 (ru) | 2008-11-11 | 2009-11-10 | Кристаллические формы гидрохлорида финголимода |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8530522B2 (https=) |
| EP (1) | EP2356090B1 (https=) |
| JP (4) | JP2012508216A (https=) |
| KR (2) | KR101393994B1 (https=) |
| CN (3) | CN104788325A (https=) |
| AU (1) | AU2009315736B2 (https=) |
| BR (1) | BRPI0921826A2 (https=) |
| CA (1) | CA2743232C (https=) |
| ES (1) | ES2643161T3 (https=) |
| MX (1) | MX2011004962A (https=) |
| PL (1) | PL2356090T3 (https=) |
| PT (1) | PT2356090T (https=) |
| RU (2) | RU2549899C2 (https=) |
| WO (1) | WO2010055028A2 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2621889B1 (en) | 2010-10-01 | 2019-07-17 | Synthon BV | Process for making fingolimod hydrochloride crystals |
| PL2632889T3 (pl) | 2010-10-28 | 2019-04-30 | Mapi Pharma Ltd | Związki pośrednie i sposób wytwarzania fingolimodu |
| WO2012071524A1 (en) | 2010-11-24 | 2012-05-31 | Ratiopharm Gmbh | Arylsulfonate salts of fingolimod and processes for preparation thereof |
| US9266816B2 (en) | 2010-11-25 | 2016-02-23 | Shilpa Medicare Limited | Fingolimod polymorphs and their processes |
| EP2658840B1 (en) | 2010-12-28 | 2019-07-03 | Synthon BV | Process for making fingolimod hydrochloride crystals |
| WO2012097330A2 (en) * | 2011-01-14 | 2012-07-19 | University Of Washington | Compositions and methods for treating degenerative muscle conditions |
| EP2702034A4 (en) | 2011-04-29 | 2015-03-25 | Reddys Lab Ltd Dr | PREPARATION OF FINGOLIMOD AND ITS SALTS |
| US9751834B2 (en) | 2011-05-26 | 2017-09-05 | Gri Bio, Inc. | Oxygenated amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives and their medical use |
| EP2739606B1 (en) | 2011-05-26 | 2016-04-27 | Jado Technologies GmbH | Hydroxy-substituted amino and ammonium derivatives and their medical use |
| DK2809318T3 (da) | 2011-05-26 | 2019-07-22 | Gri Bio Inc | Ammoniumholdige sulfonsyre-, phosphonsyre- og carboxylsyrederivater og disses medicinske anvendelse |
| WO2013019872A1 (en) | 2011-08-01 | 2013-02-07 | Teva Pharmaceutical Industries Ltd. | Process for preparing pharmaceutical compositions comprising fingolimod |
| WO2013091704A1 (en) * | 2011-12-22 | 2013-06-27 | Synthon Bv | Pharmaceutical composition comprising fingolimod |
| CN102887829B (zh) * | 2012-09-05 | 2014-07-02 | 中国科学院上海药物研究所 | 芬戈莫德粘酸盐及其晶体的制备方法和用途 |
| EP2945927A4 (en) * | 2013-01-17 | 2017-01-18 | Shilpa Medicare Limited | Process for preparation of fingolimod and its salts |
| US9815772B2 (en) * | 2013-03-05 | 2017-11-14 | Biocon Limited | Process for the preparation of 2-amino-1,3-propane diol compounds and salts thereof |
| EP3027174B1 (en) | 2013-07-29 | 2019-07-24 | Aizant Drug Research Solutions Private Limited | Pharmaceutical compositions of fingolimod |
| WO2016042493A1 (en) * | 2014-09-19 | 2016-03-24 | Aizant Drug Research Pvt. Ltd | Pharmaceutical compositions of fingolimod |
| US9925138B2 (en) | 2015-01-20 | 2018-03-27 | Handa Pharmaceuticals, Llc | Stable solid fingolimod dosage forms |
| RU2627691C1 (ru) * | 2016-07-06 | 2017-08-10 | Олег Ростиславович Михайлов | Кристаллическая η-модификация 2-амино-2-(2-(4-октилфенил)этил)пропан-1,3-диол гидрохлорида, способ её получения и фармацевтическая композиция на её основе |
| CN106860440A (zh) * | 2017-01-16 | 2017-06-20 | 南京医科大学第二附属医院 | 盐酸芬戈莫德在制备治疗系统性红斑狼疮脑病药物中的应用 |
| CN106667981B (zh) * | 2017-01-16 | 2019-05-14 | 南京医科大学第二附属医院 | 盐酸芬戈莫德在制备治疗药物性肝损伤药物中的应用 |
| GR1009654B (el) | 2018-08-31 | 2019-11-18 | Φαρματεν Α.Β.Ε.Ε. | Φαρμακευτικο σκευασμα που περιλαμβανει εναν ανοσοτροποποιητικο παραγοντα και μεθοδος για την παρασκευη αυτου |
| WO2020245775A1 (en) * | 2019-06-05 | 2020-12-10 | Biocon Limited | Crystalline forms of 2-amino-2-(2-(4-octylphenyl) ethyl) propane-1,3-diol |
| AU2020372647B2 (en) | 2019-10-31 | 2026-02-05 | Idorsia Pharmaceuticals Ltd | Combination of a CXCR7 antagonist with an S1P1 receptor modulator |
| JP2024521882A (ja) | 2021-05-31 | 2024-06-04 | 上海雲晟研新生物科技有限公司 | フィンゴリモド薬用塩、製造方法、それを含む医薬組成物及び使用 |
| EP4212156A1 (en) | 2022-01-13 | 2023-07-19 | Abivax | Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a s1p receptor modulator |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5604229A (en) | 1992-10-21 | 1997-02-18 | Yoshitomi Pharmaceutical Industries, Ltd. | 2-amino-1,3-propanediol compound and immunosuppressant |
| US6476004B1 (en) * | 1996-07-18 | 2002-11-05 | Mitsubishi Pharma Corporation | Pharmaceutical composition |
| JP4079505B2 (ja) * | 1998-04-28 | 2008-04-23 | 田辺三菱製薬株式会社 | ２−アミノ−２−［２−（４−オクチルフェニル）エチル］プロパン−１，３−ジオールの新規な製造法 |
| EP1457478B1 (en) * | 1998-11-11 | 2017-07-19 | Novartis AG | Production of 2-amino-2-[2-(4-alkyl-phenyl)ethyl]propane-1,3-diols |
| PT1031347E (pt) * | 1999-01-27 | 2002-09-30 | Idea Ag | Transporte/imunizacao transnasal com veiculos muitissimo adaptaveis |
| CN1230421C (zh) * | 1999-02-10 | 2005-12-07 | 三菱制药株式会社 | 酰胺化合物及其药物用途 |
| CN1144779C (zh) * | 1999-03-11 | 2004-04-07 | 杭州中美华东制药有限公司 | 制备2-[2-(4-烷基苯基)-乙基]-2-氨基-丙二醇的方法以及其中制得的中间产物 |
| ES2322442T3 (es) * | 2001-06-08 | 2009-06-22 | Novartis Ag | Tratamiento o profilaxis del rechazo de injertos de celulas productoras de insulina. |
| US20030144712A1 (en) * | 2001-12-20 | 2003-07-31 | Jackson Streeter, M.D. | Methods for overcoming organ transplant rejection |
| PL372103A1 (en) * | 2002-05-16 | 2005-07-11 | Novartis Ag | Use of edg receptor binding agents in cancer |
| GB0217152D0 (en) * | 2002-07-24 | 2002-09-04 | Novartis Ag | Organic compounds |
| CA2521325C (en) | 2003-04-08 | 2010-09-14 | Novartis Ag | Solid pharmaceutical compositions comprising a s1p receptor agonist and a sugar alcohol |
| CN1212308C (zh) * | 2003-07-24 | 2005-07-27 | 漆又毛 | 2－氨基－2－（2－（4－辛基苯基）乙基）－1，3－丙二醇盐酸盐的制备方法 |
| CN1241903C (zh) * | 2003-10-14 | 2006-02-15 | 马启明 | 制备2－对辛基苯乙基－2－氨基丙二醇的方法 |
| TWI418350B (zh) * | 2005-06-24 | 2013-12-11 | Sankyo Co | 含有ｐｐａｒ調節劑之醫藥組成物的用途 |
| RU2008116578A (ru) * | 2005-09-30 | 2009-11-10 | Новартис АГ (CH) | Применение ингибиторов dpp-iv для лечения аутоиммунных заболеваний и отторжения трансплантата |
| CN1310869C (zh) * | 2005-11-22 | 2007-04-18 | 江苏吴中苏药医药开发有限责任公司 | 2－氨基－2－[2－(4－烷基苯基)乙基]－1,3－丙二醇的制备方法 |
| CN100548968C (zh) * | 2006-03-01 | 2009-10-14 | 徐州师范大学 | 一种制备2-对辛基苯乙基-2-氨基丙二醇盐酸盐的方法 |
| ES2414205T3 (es) * | 2006-06-02 | 2013-07-18 | The Ohio State University Research Foundation | Agentes terapéuticos para el tratamiento de linfoma de células del manto |
| KR20090057399A (ko) * | 2006-09-26 | 2009-06-05 | 노파르티스 아게 | Ｓ１ｐ 조정제를 포함하는 제약 조성물 |
| KR20110020928A (ko) * | 2008-06-20 | 2011-03-03 | 노파르티스 아게 | 다발성 경화증을 치료하기 위한 소아용 조성물 |
| EP2621889B1 (en) | 2010-10-01 | 2019-07-17 | Synthon BV | Process for making fingolimod hydrochloride crystals |
-
2009
- 2009-11-10 CA CA2743232A patent/CA2743232C/en active Active
- 2009-11-10 US US13/128,825 patent/US8530522B2/en not_active Expired - Fee Related
- 2009-11-10 WO PCT/EP2009/064891 patent/WO2010055028A2/en not_active Ceased
- 2009-11-10 CN CN201510141353.8A patent/CN104788325A/zh active Pending
- 2009-11-10 PL PL09748350T patent/PL2356090T3/pl unknown
- 2009-11-10 CN CN201710377640.8A patent/CN107233336A/zh active Pending
- 2009-11-10 EP EP09748350.7A patent/EP2356090B1/en active Active
- 2009-11-10 RU RU2011123371/04A patent/RU2549899C2/ru active
- 2009-11-10 AU AU2009315736A patent/AU2009315736B2/en not_active Ceased
- 2009-11-10 JP JP2011535130A patent/JP2012508216A/ja not_active Withdrawn
- 2009-11-10 RU RU2015111229/04A patent/RU2015111229A/ru not_active Application Discontinuation
- 2009-11-10 CN CN200980144998XA patent/CN102209705A/zh active Pending
- 2009-11-10 KR KR1020117010560A patent/KR101393994B1/ko not_active Expired - Fee Related
- 2009-11-10 KR KR1020137024001A patent/KR20130109254A/ko not_active Withdrawn
- 2009-11-10 MX MX2011004962A patent/MX2011004962A/es active IP Right Grant
- 2009-11-10 BR BRPI0921826A patent/BRPI0921826A2/pt not_active Application Discontinuation
- 2009-11-10 ES ES09748350.7T patent/ES2643161T3/es active Active
- 2009-11-10 PT PT97483507T patent/PT2356090T/pt unknown
-
2013
- 2013-08-12 US US13/964,817 patent/US20140051766A1/en not_active Abandoned
-
2014
- 2014-02-06 JP JP2014020950A patent/JP2014139179A/ja not_active Withdrawn
-
2015
- 2015-09-03 JP JP2015173474A patent/JP2016028056A/ja not_active Withdrawn
-
2017
- 2017-09-07 JP JP2017172276A patent/JP2018035160A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010055028A3 (en) | 2010-07-08 |
| WO2010055028A2 (en) | 2010-05-20 |
| EP2356090A2 (en) | 2011-08-17 |
| ES2643161T3 (es) | 2017-11-21 |
| AU2009315736A1 (en) | 2010-05-20 |
| PL2356090T3 (pl) | 2017-12-29 |
| US20110229501A1 (en) | 2011-09-22 |
| JP2014139179A (ja) | 2014-07-31 |
| JP2016028056A (ja) | 2016-02-25 |
| RU2549899C2 (ru) | 2015-05-10 |
| KR101393994B1 (ko) | 2014-05-14 |
| PT2356090T (pt) | 2017-10-16 |
| AU2009315736B2 (en) | 2013-08-29 |
| RU2011123371A (ru) | 2012-12-20 |
| JP2012508216A (ja) | 2012-04-05 |
| CA2743232C (en) | 2015-12-29 |
| JP2018035160A (ja) | 2018-03-08 |
| CN104788325A (zh) | 2015-07-22 |
| BRPI0921826A2 (pt) | 2016-01-12 |
| KR20130109254A (ko) | 2013-10-07 |
| CN107233336A (zh) | 2017-10-10 |
| US8530522B2 (en) | 2013-09-10 |
| CN102209705A (zh) | 2011-10-05 |
| MX2011004962A (es) | 2011-05-30 |
| US20140051766A1 (en) | 2014-02-20 |
| CA2743232A1 (en) | 2010-05-20 |
| RU2015111229A (ru) | 2015-11-20 |
| EP2356090B1 (en) | 2017-07-05 |
| KR20110069156A (ko) | 2011-06-22 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20191010 |