RU2014134845A - Терапевтическое средство против диабета - Google Patents
Терапевтическое средство против диабета Download PDFInfo
- Publication number
- RU2014134845A RU2014134845A RU2014134845A RU2014134845A RU2014134845A RU 2014134845 A RU2014134845 A RU 2014134845A RU 2014134845 A RU2014134845 A RU 2014134845A RU 2014134845 A RU2014134845 A RU 2014134845A RU 2014134845 A RU2014134845 A RU 2014134845A
- Authority
- RU
- Russia
- Prior art keywords
- therapeutic
- group
- impaired glucose
- prophylactic agent
- glucose metabolism
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title claims abstract 17
- 206010012601 diabetes mellitus Diseases 0.000 title claims abstract 6
- 230000000069 prophylactic effect Effects 0.000 claims abstract 16
- 239000003795 chemical substances by application Substances 0.000 claims abstract 13
- 201000010099 disease Diseases 0.000 claims abstract 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract 10
- 230000004153 glucose metabolism Effects 0.000 claims abstract 10
- 230000001771 impaired effect Effects 0.000 claims abstract 10
- WYKHSBAVLOPISI-UHFFFAOYSA-N 2-phenyl-1,3-thiazole Chemical class C1=CSC(C=2C=CC=CC=2)=N1 WYKHSBAVLOPISI-UHFFFAOYSA-N 0.000 claims abstract 4
- 150000003839 salts Chemical class 0.000 claims abstract 4
- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims abstract 3
- 125000004195 4-methylpiperazin-1-yl group Chemical group [H]C([H])([H])N1C([H])([H])C([H])([H])N(*)C([H])([H])C1([H])[H] 0.000 claims abstract 2
- 208000002705 Glucose Intolerance Diseases 0.000 claims abstract 2
- 206010022489 Insulin Resistance Diseases 0.000 claims abstract 2
- 239000004480 active ingredient Substances 0.000 claims abstract 2
- 125000003545 alkoxy group Chemical group 0.000 claims abstract 2
- 239000003472 antidiabetic agent Substances 0.000 claims abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims abstract 2
- 229940125904 compound 1 Drugs 0.000 claims abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 claims abstract 2
- BQSJTQLCZDPROO-UHFFFAOYSA-N febuxostat Chemical compound C1=C(C#N)C(OCC(C)C)=CC=C1C1=NC(C)=C(C(O)=O)S1 BQSJTQLCZDPROO-UHFFFAOYSA-N 0.000 claims abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims abstract 2
- 229940126904 hypoglycaemic agent Drugs 0.000 claims abstract 2
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 claims abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims abstract 2
- 125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 claims abstract 2
- 201000009104 prediabetes syndrome Diseases 0.000 claims abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 1
- 125000006828 (C2-C7) alkoxycarbonyl group Chemical group 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012-015351 | 2012-01-27 | ||
| JP2012015351 | 2012-01-27 | ||
| PCT/JP2013/051627 WO2013111870A1 (ja) | 2012-01-27 | 2013-01-25 | 糖尿病の治療薬 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2014134845A true RU2014134845A (ru) | 2016-03-20 |
Family
ID=48873581
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2014134845A RU2014134845A (ru) | 2012-01-27 | 2013-01-25 | Терапевтическое средство против диабета |
Country Status (15)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104628673A (zh) * | 2015-02-10 | 2015-05-20 | 佛山市赛维斯医药科技有限公司 | 一类含叔丁基脒结构的腈基苯噻唑羧酸酰胺类化合物及用途 |
| CN104610188B (zh) * | 2015-02-10 | 2016-07-27 | 佛山市赛维斯医药科技有限公司 | 含苯基脒结构的腈基苯噻唑羧酸酰胺类化合物、其制备及用途 |
| CN104628671B (zh) * | 2015-02-10 | 2016-04-13 | 佛山市赛维斯医药科技有限公司 | 含苯基脒结构的硝基苯噻唑羧酸酰胺类化合物及用途 |
| CN104628672A (zh) * | 2015-02-10 | 2015-05-20 | 佛山市赛维斯医药科技有限公司 | 一类含苯基脒结构的烷氧苯基噻唑羧酸酰胺类化合物及用途 |
| CN104610190B (zh) * | 2015-02-10 | 2016-08-17 | 佛山市赛维斯医药科技有限公司 | 一类含环丙基脒结构的卤代苯基噻唑羧酸酰胺类化合物及用途 |
| KR102473677B1 (ko) * | 2015-08-17 | 2022-12-02 | 삼성디스플레이 주식회사 | 액정 표시 장치 |
| JP6732004B2 (ja) | 2016-02-19 | 2020-07-29 | 国立大学法人鳥取大学 | 認知症治療薬または予防薬 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0513379T3 (da) | 1990-11-30 | 1996-09-30 | Teijin Ltd | 2-Arylthiazolderivater og farmaceutisk præparat indeholdende sådanne |
| HUP9902721A2 (hu) * | 1997-11-25 | 1999-12-28 | The Procter & Gamble Co. | Tömény textillágyító készítmény és ehhez alkalmazható magas telítetlenségű textillágyító vegyület |
| US20050074442A1 (en) * | 2002-03-13 | 2005-04-07 | Natarajan Ranganathan | Compositions and methods for augmenting kidney function |
| WO2006012438A2 (en) * | 2004-07-21 | 2006-02-02 | University Of Florida Research Foundation, Inc. | Compositions and methods for treatment and prevention of insulin resistance |
| JP2009501795A (ja) * | 2005-07-21 | 2009-01-22 | ユニバーシティ オブ フロリダ リサーチファウンデーション インコーポレイティッド | 高尿酸血に関連する健康状態の治療及び予防のための組成物及び方法 |
| JP5242393B2 (ja) | 2005-08-03 | 2013-07-24 | タケダ ファーマシューティカルズ ユー．エス．エー． インコーポレイティド | 高血圧症の治療方法 |
| EP1957064A4 (en) * | 2005-11-21 | 2010-01-06 | Tap Pharmaceutical Prod Inc | TREATMENT OF QT INTERVAL EXTENSION AND RELEVANT DISEASES |
| JP2007210978A (ja) * | 2006-02-13 | 2007-08-23 | Hiroshima Univ | 耐糖能障害、ｉｉ型糖尿病、高脂血症、メタボリックシンドローム、内臓脂肪型肥満、脂肪肝または非アルコール性脂肪性肝炎の予防・治療剤 |
| JP2010509372A (ja) | 2006-11-13 | 2010-03-25 | タケダ・フアーマシユーテイカルズ・ノース・アメリカ・インコーポレイテツド | キサンチン酸化還元酵素阻害剤を使用する腎機能保持方法 |
| US8084483B2 (en) * | 2007-11-27 | 2011-12-27 | Ardea Biosciences, Inc. | Compounds and compositions and methods of use |
| CN102015726B (zh) * | 2008-03-31 | 2014-07-23 | C&C新药研究所 | 杂环衍生物 |
| CA2722624C (en) * | 2008-04-30 | 2017-03-21 | Wellstat Therapeutics Corporation | Tetrazole compounds for reducing uric acid |
| US8791077B2 (en) * | 2008-05-22 | 2014-07-29 | Astrazeneca Ab | Method for treating hyperuricemia employing an SGLT2 inhibitor and composition containing same |
| EP2398319A4 (en) * | 2008-10-19 | 2012-11-14 | Richard J Johnson | THERAPEUTIC COMPOSITIONS AND METHODS FOR TREATING CHRONIC NEPHITIA ASSOCIATED WITH METABOLIC IMBALANCE |
| EP2470268A4 (en) * | 2009-08-24 | 2012-12-26 | Wound Man Pty Ltd | PURING-ORIENTED DIAGNOSIS AND THERAPY OF WOUNDS |
| JP5865904B2 (ja) * | 2010-06-16 | 2016-02-17 | タケダ ファーマシューティカルズ ユー．エス．エー． インコーポレイティド | キサンチンオキシドレダクターゼ阻害剤またはキサンチンオキシダーゼ阻害剤の新規の調節放出剤形 |
| KR20130088755A (ko) * | 2010-06-25 | 2013-08-08 | 데이진 화-마 가부시키가이샤 | 서방성 고혈압 및 신 기능 장애 치료제 |
-
2013
- 2013-01-25 RU RU2014134845A patent/RU2014134845A/ru not_active Application Discontinuation
- 2013-01-25 MX MX2014008484A patent/MX2014008484A/es unknown
- 2013-01-25 IN IN5972DEN2014 patent/IN2014DN05972A/en unknown
- 2013-01-25 TW TW102102886A patent/TW201334779A/zh unknown
- 2013-01-25 US US14/372,961 patent/US20150005506A1/en not_active Abandoned
- 2013-01-25 WO PCT/JP2013/051627 patent/WO2013111870A1/ja not_active Ceased
- 2013-01-25 EP EP13740913.2A patent/EP2808018B1/en not_active Not-in-force
- 2013-01-25 JP JP2013555326A patent/JP5924699B2/ja not_active Expired - Fee Related
- 2013-01-25 HK HK15101890.2A patent/HK1201209A1/xx unknown
- 2013-01-25 CA CA2862602A patent/CA2862602A1/en not_active Abandoned
- 2013-01-25 BR BR112014017902A patent/BR112014017902A2/pt not_active IP Right Cessation
- 2013-01-25 KR KR1020147020342A patent/KR20140134266A/ko not_active Withdrawn
- 2013-01-25 AU AU2013212865A patent/AU2013212865A1/en not_active Abandoned
- 2013-01-25 CN CN201380006730.6A patent/CN104066430A/zh active Pending
- 2013-01-25 AR ARP130100233A patent/AR089812A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2808018A1 (en) | 2014-12-03 |
| BR112014017902A2 (pt) | 2017-08-22 |
| CN104066430A (zh) | 2014-09-24 |
| AR089812A1 (es) | 2014-09-17 |
| JPWO2013111870A1 (ja) | 2015-05-11 |
| AU2013212865A1 (en) | 2014-08-14 |
| HK1201209A1 (en) | 2015-08-28 |
| EP2808018B1 (en) | 2018-03-14 |
| WO2013111870A1 (ja) | 2013-08-01 |
| IN2014DN05972A (cg-RX-API-DMAC7.html) | 2015-06-26 |
| CA2862602A1 (en) | 2013-08-01 |
| JP5924699B2 (ja) | 2016-05-25 |
| KR20140134266A (ko) | 2014-11-21 |
| TW201334779A (zh) | 2013-09-01 |
| US20150005506A1 (en) | 2015-01-01 |
| MX2014008484A (es) | 2014-10-14 |
| EP2808018A4 (en) | 2015-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20160830 |