RU2014111078A - Композиции и способы для лечения нейродегенеративного заболевания - Google Patents

Композиции и способы для лечения нейродегенеративного заболевания Download PDF

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RU2014111078A
RU2014111078A RU2014111078/15A RU2014111078A RU2014111078A RU 2014111078 A RU2014111078 A RU 2014111078A RU 2014111078/15 A RU2014111078/15 A RU 2014111078/15A RU 2014111078 A RU2014111078 A RU 2014111078A RU 2014111078 A RU2014111078 A RU 2014111078A
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compound
alkyl
sigma
haloalkyl
halogen
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RU2014111078/15A
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Russian (ru)
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Сьюзан М. КАТАЛАНО
Гилберт РИШТОН
Николас Дж. ИЗЗО
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Когнишн Терапьютикс, Инк.
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    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
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    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
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RU2014111078/15A 2011-08-25 2012-08-27 Композиции и способы для лечения нейродегенеративного заболевания RU2014111078A (ru)

Applications Claiming Priority (5)

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US201161527584P 2011-08-25 2011-08-25
US61/527,584 2011-08-25
US201161527963P 2011-08-26 2011-08-26
US61/527,963 2011-08-26
PCT/US2012/052578 WO2013029060A2 (en) 2011-08-25 2012-08-27 Compositions and methods for treating neurodegenerative disease

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EP (1) EP2747768A4 (https=)
JP (1) JP2014529613A (https=)
CN (2) CN104053436A (https=)
AU (2) AU2012298617B2 (https=)
BR (1) BR112014004416A2 (https=)
CA (1) CA2846611A1 (https=)
HK (1) HK1202246A1 (https=)
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RU2014111079A (ru) * 2011-08-25 2015-09-27 Когнишн Терапьютикс, Инк. Композиции и способы для лечения нейродегенеративного заболевания
WO2015066019A1 (en) * 2013-10-28 2015-05-07 Drexel University Novel treatments for attention and cognitive disorders, and for dementia associated with a neurodegenerative disorder
DK3099296T3 (en) * 2014-01-31 2019-04-15 Cognition Therapeutics Inc ISO-INDOLINE DERIVATIVES, COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE
WO2016178852A1 (en) * 2015-05-04 2016-11-10 The Trustees Of The University Of Pennsylvania 211-astatine containing radiotherapeutics for the treatment of cancer
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