RU2014110624A - Ингибиторы поли(адф-рибоза)-полимеразы - Google Patents

Ингибиторы поли(адф-рибоза)-полимеразы Download PDF

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Publication number
RU2014110624A
RU2014110624A RU2014110624/04A RU2014110624A RU2014110624A RU 2014110624 A RU2014110624 A RU 2014110624A RU 2014110624/04 A RU2014110624/04 A RU 2014110624/04A RU 2014110624 A RU2014110624 A RU 2014110624A RU 2014110624 A RU2014110624 A RU 2014110624A
Authority
RU
Russia
Prior art keywords
acetamide
methoxyphenyl
benzenesulfinyl
sulfinyl
chlorobenzenesulfinyl
Prior art date
Application number
RU2014110624/04A
Other languages
English (en)
Russian (ru)
Inventor
Ненси-Эллен ХЭЙНС
Николас Джон Сильвестер ХЬЮБИ
Натан Роберт СКОТТ
Original Assignee
Ф. Хоффманн-Ля Рош Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ф. Хоффманн-Ля Рош Аг filed Critical Ф. Хоффманн-Ля Рош Аг
Publication of RU2014110624A publication Critical patent/RU2014110624A/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/18—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
RU2014110624/04A 2011-09-01 2012-08-29 Ингибиторы поли(адф-рибоза)-полимеразы RU2014110624A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161529942P 2011-09-01 2011-09-01
US61/529,942 2011-09-01
PCT/EP2012/066721 WO2013030205A1 (en) 2011-09-01 2012-08-29 Parp inhibitors

Publications (1)

Publication Number Publication Date
RU2014110624A true RU2014110624A (ru) 2015-10-10

Family

ID=46796563

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2014110624/04A RU2014110624A (ru) 2011-09-01 2012-08-29 Ингибиторы поли(адф-рибоза)-полимеразы

Country Status (9)

Country Link
EP (1) EP2758370A1 (ko)
JP (1) JP2014531416A (ko)
KR (1) KR20140062096A (ko)
CN (1) CN103906730A (ko)
BR (1) BR112014005011A2 (ko)
CA (1) CA2846429A1 (ko)
MX (1) MX2014002343A (ko)
RU (1) RU2014110624A (ko)
WO (1) WO2013030205A1 (ko)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5441864A (en) * 1977-09-02 1979-04-03 Sankyo Co Ltd Beta-lactam homolog and its preparation
US7642277B2 (en) * 2002-12-04 2010-01-05 Boehringer Ingelheim International Gmbh Non-nucleoside reverse transcriptase inhibitors
JP2009539963A (ja) * 2006-06-15 2009-11-19 クドス ファーマシューティカルズ リミテッド Ｐａｒｐ阻害剤
WO2010139966A1 (en) * 2009-06-05 2010-12-09 Oslo University Hospital Hf Azole derivatives as wtn pathway inhibitors

Also Published As

Publication number Publication date
EP2758370A1 (en) 2014-07-30
BR112014005011A2 (pt) 2017-05-30
CA2846429A1 (en) 2013-03-07
KR20140062096A (ko) 2014-05-22
MX2014002343A (es) 2014-04-30
CN103906730A (zh) 2014-07-02
JP2014531416A (ja) 2014-11-27
WO2013030205A1 (en) 2013-03-07

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Legal Events

Date Code Title Description
FA93 Acknowledgement of application withdrawn (no request for examination)

Effective date: 20150831