JPS5441864A - Beta-lactam homolog and its preparation - Google Patents
Beta-lactam homolog and its preparationInfo
- Publication number
- JPS5441864A JPS5441864A JP10570377A JP10570377A JPS5441864A JP S5441864 A JPS5441864 A JP S5441864A JP 10570377 A JP10570377 A JP 10570377A JP 10570377 A JP10570377 A JP 10570377A JP S5441864 A JPS5441864 A JP S5441864A
- Authority
- JP
- Japan
- Prior art keywords
- lactam
- alkyl
- preparation
- homolog
- beta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:β-Lactams of formulaI[R1 is (alkyl, aryl or aralkyl)-(thio or sulfinyl), akloxycarbonyl; R2 is alkyl, cycloalkyl, aralkyl, acyl; R3 is H, alkyl].
EXAMPLE: 3-Phenylthio-N-n-butyl-2-azetidinone.
USE: Synthetic intermediates for cardicin with β-lactam ring, and antibiotic.
PREPARATION: An acidamide of formula II is treated with more than 2 equivalent quantities of a base to form a dianion of formula III, to which is made to act an alkyl dihalide of formula IV (X is Br or I) to afford a β-lactam of formulaI.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10570377A JPS5441864A (en) | 1977-09-02 | 1977-09-02 | Beta-lactam homolog and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10570377A JPS5441864A (en) | 1977-09-02 | 1977-09-02 | Beta-lactam homolog and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5441864A true JPS5441864A (en) | 1979-04-03 |
Family
ID=14414713
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10570377A Pending JPS5441864A (en) | 1977-09-02 | 1977-09-02 | Beta-lactam homolog and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5441864A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103906730A (en) * | 2011-09-01 | 2014-07-02 | 霍夫曼-拉罗奇有限公司 | Parp inhibitors |
-
1977
- 1977-09-02 JP JP10570377A patent/JPS5441864A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103906730A (en) * | 2011-09-01 | 2014-07-02 | 霍夫曼-拉罗奇有限公司 | Parp inhibitors |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PH15706A (en) | Esters of penicillanic acid 1,1-dioxide | |
ES8207498A1 (en) | Aminocyclopentane alkenoic acids and esters and pharmaceutical compositions | |
HK49688A (en) | Antifibrinolytically active compounds | |
IT8022585A0 (en) | PROCEDURE FOR THE PRODUCTION OF ANTIBIOTIC MIXTURES FROM THE CULTIVATION OF ASPERGILLUS NIDULANS ROSEUS VARIETY | |
EP0189960A3 (en) | Novel insecticidal 1,3-thiazole derivatives | |
JPS5441864A (en) | Beta-lactam homolog and its preparation | |
JPS56100771A (en) | Benzoxazole derivative | |
JPS5690088A (en) | Novel cephalosporin analog compound | |
JPS554337A (en) | Cephalosporin analogs | |
IE820342L (en) | Penicillins | |
JPS55120575A (en) | Cis-2,3-epoxy-4-lower alkoxyphenylbutanoic acid derivative and its production | |
FI834594A (en) | ANTIBIOTICS A51568 FACTOR ANA OCH B. | |
JPS56142282A (en) | Penem-3-carboxylic acid derivative and its preparation | |
JPS5414956A (en) | Novel 3-amino-4-homoisotwistan derivative | |
JPS53135996A (en) | Preparation of cephalosporin compounds | |
JPS5587788A (en) | Cephalosporin analog | |
IL57084A (en) | Production of semi-synthetic beta-lactam antibiotics | |
JPS5446799A (en) | Penicillins and cephalosporins | |
JPS5759897A (en) | Thiazolineazatidinone | |
JPS5495506A (en) | Ring breakage method of 2*6*66trimethyll 5*66dihydroo4hhpyrane | |
EP0177897A3 (en) | Antibacterial 7beta-heterocyclic-cephem | |
IL63743A0 (en) | Production of alkyl and alkoxyalkyl substituted benzene compounds | |
NZ193020A (en) | Preparation of penicillanic acid 1,1-dioxide and intermediates therefor | |
JPS57120591A (en) | Novel penem derivative | |
JPS53128638A (en) | Colored organic compounds, their preparation, and coloring method using the m |