JPS5441864A - Beta-lactam homolog and its preparation - Google Patents

Beta-lactam homolog and its preparation

Info

Publication number
JPS5441864A
JPS5441864A JP10570377A JP10570377A JPS5441864A JP S5441864 A JPS5441864 A JP S5441864A JP 10570377 A JP10570377 A JP 10570377A JP 10570377 A JP10570377 A JP 10570377A JP S5441864 A JPS5441864 A JP S5441864A
Authority
JP
Japan
Prior art keywords
lactam
alkyl
preparation
homolog
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10570377A
Other languages
Japanese (ja)
Inventor
Koichi Hirai
Yuji Iwano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Priority to JP10570377A priority Critical patent/JPS5441864A/en
Publication of JPS5441864A publication Critical patent/JPS5441864A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:β-Lactams of formulaI[R1 is (alkyl, aryl or aralkyl)-(thio or sulfinyl), akloxycarbonyl; R2 is alkyl, cycloalkyl, aralkyl, acyl; R3 is H, alkyl].
EXAMPLE: 3-Phenylthio-N-n-butyl-2-azetidinone.
USE: Synthetic intermediates for cardicin with β-lactam ring, and antibiotic.
PREPARATION: An acidamide of formula II is treated with more than 2 equivalent quantities of a base to form a dianion of formula III, to which is made to act an alkyl dihalide of formula IV (X is Br or I) to afford a β-lactam of formulaI.
COPYRIGHT: (C)1979,JPO&Japio
JP10570377A 1977-09-02 1977-09-02 Beta-lactam homolog and its preparation Pending JPS5441864A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10570377A JPS5441864A (en) 1977-09-02 1977-09-02 Beta-lactam homolog and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10570377A JPS5441864A (en) 1977-09-02 1977-09-02 Beta-lactam homolog and its preparation

Publications (1)

Publication Number Publication Date
JPS5441864A true JPS5441864A (en) 1979-04-03

Family

ID=14414713

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10570377A Pending JPS5441864A (en) 1977-09-02 1977-09-02 Beta-lactam homolog and its preparation

Country Status (1)

Country Link
JP (1) JPS5441864A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103906730A (en) * 2011-09-01 2014-07-02 霍夫曼-拉罗奇有限公司 Parp inhibitors

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103906730A (en) * 2011-09-01 2014-07-02 霍夫曼-拉罗奇有限公司 Parp inhibitors

Similar Documents

Publication Publication Date Title
PH15706A (en) Esters of penicillanic acid 1,1-dioxide
ES8207498A1 (en) Aminocyclopentane alkenoic acids and esters and pharmaceutical compositions
HK49688A (en) Antifibrinolytically active compounds
IT8022585A0 (en) PROCEDURE FOR THE PRODUCTION OF ANTIBIOTIC MIXTURES FROM THE CULTIVATION OF ASPERGILLUS NIDULANS ROSEUS VARIETY
EP0189960A3 (en) Novel insecticidal 1,3-thiazole derivatives
JPS5441864A (en) Beta-lactam homolog and its preparation
JPS56100771A (en) Benzoxazole derivative
JPS5690088A (en) Novel cephalosporin analog compound
JPS554337A (en) Cephalosporin analogs
IE820342L (en) Penicillins
JPS55120575A (en) Cis-2,3-epoxy-4-lower alkoxyphenylbutanoic acid derivative and its production
FI834594A (en) ANTIBIOTICS A51568 FACTOR ANA OCH B.
JPS56142282A (en) Penem-3-carboxylic acid derivative and its preparation
JPS5414956A (en) Novel 3-amino-4-homoisotwistan derivative
JPS53135996A (en) Preparation of cephalosporin compounds
JPS5587788A (en) Cephalosporin analog
IL57084A (en) Production of semi-synthetic beta-lactam antibiotics
JPS5446799A (en) Penicillins and cephalosporins
JPS5759897A (en) Thiazolineazatidinone
JPS5495506A (en) Ring breakage method of 2*6*66trimethyll 5*66dihydroo4hhpyrane
EP0177897A3 (en) Antibacterial 7beta-heterocyclic-cephem
IL63743A0 (en) Production of alkyl and alkoxyalkyl substituted benzene compounds
NZ193020A (en) Preparation of penicillanic acid 1,1-dioxide and intermediates therefor
JPS57120591A (en) Novel penem derivative
JPS53128638A (en) Colored organic compounds, their preparation, and coloring method using the m