RU2013118021A - Способы и композиции для лечения сахарного диабета и дислипидемии - Google Patents
Способы и композиции для лечения сахарного диабета и дислипидемии Download PDFInfo
- Publication number
- RU2013118021A RU2013118021A RU2013118021/15A RU2013118021A RU2013118021A RU 2013118021 A RU2013118021 A RU 2013118021A RU 2013118021/15 A RU2013118021/15 A RU 2013118021/15A RU 2013118021 A RU2013118021 A RU 2013118021A RU 2013118021 A RU2013118021 A RU 2013118021A
- Authority
- RU
- Russia
- Prior art keywords
- alkyl
- cycloalkyl
- alkoxy
- hydroxy
- independently selected
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract 8
- 238000000034 method Methods 0.000 title claims 9
- 206010012601 diabetes mellitus Diseases 0.000 title claims 6
- 208000032928 Dyslipidaemia Diseases 0.000 title claims 3
- 208000017170 Lipid metabolism disease Diseases 0.000 title claims 3
- 125000000217 alkyl group Chemical group 0.000 claims abstract 69
- 125000000753 cycloalkyl group Chemical group 0.000 claims abstract 34
- 125000003545 alkoxy group Chemical group 0.000 claims abstract 26
- 125000004356 hydroxy functional group Chemical group O* 0.000 claims abstract 22
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract 18
- 239000001257 hydrogen Substances 0.000 claims abstract 18
- 150000002431 hydrogen Chemical class 0.000 claims abstract 15
- 125000004432 carbon atom Chemical group C* 0.000 claims abstract 14
- 150000001875 compounds Chemical class 0.000 claims abstract 14
- 125000004122 cyclic group Chemical group 0.000 claims abstract 14
- 150000001412 amines Chemical group 0.000 claims abstract 13
- 125000001188 haloalkyl group Chemical group 0.000 claims abstract 10
- 229910052760 oxygen Inorganic materials 0.000 claims abstract 10
- 150000003839 salts Chemical class 0.000 claims abstract 10
- 125000001931 aliphatic group Chemical group 0.000 claims abstract 7
- 125000003118 aryl group Chemical group 0.000 claims abstract 7
- 125000000524 functional group Chemical group 0.000 claims abstract 7
- 125000004093 cyano group Chemical group *C#N 0.000 claims abstract 5
- 125000001072 heteroaryl group Chemical group 0.000 claims abstract 5
- 125000000592 heterocycloalkyl group Chemical group 0.000 claims abstract 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract 3
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims abstract 3
- 239000001301 oxygen Substances 0.000 claims abstract 3
- 125000005842 heteroatom Chemical group 0.000 claims 6
- 239000003937 drug carrier Substances 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 208000024172 Cardiovascular disease Diseases 0.000 claims 1
- 206010022489 Insulin Resistance Diseases 0.000 claims 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/51—Y being a hydrogen or a carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/58—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/60—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C255/46—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C31/27—Polyhydroxylic alcohols containing saturated rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/04—Saturated ethers
- C07C43/115—Saturated ethers containing carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/132—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/12—Saturated polycyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/15—Saturated compounds containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/608—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a ring other than a six-membered aromatic ring in the acid moiety
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38444610P | 2010-09-20 | 2010-09-20 | |
| US61/384,446 | 2010-09-20 | ||
| PCT/US2011/052318 WO2012040177A1 (en) | 2010-09-20 | 2011-09-20 | Methods and compositions for treatment of diabetes and dyslipidemia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2013118021A true RU2013118021A (ru) | 2014-10-27 |
Family
ID=45818296
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2013118021/15A RU2013118021A (ru) | 2010-09-20 | 2011-09-20 | Способы и композиции для лечения сахарного диабета и дислипидемии |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8623897B2 (https=) |
| EP (1) | EP2618824A4 (https=) |
| JP (1) | JP2013537240A (https=) |
| KR (1) | KR20140009125A (https=) |
| CN (1) | CN103327974A (https=) |
| AU (1) | AU2011305610A1 (https=) |
| BR (1) | BR112013008675A2 (https=) |
| CA (1) | CA2812109A1 (https=) |
| MX (1) | MX2013003078A (https=) |
| RU (1) | RU2013118021A (https=) |
| SG (1) | SG188996A1 (https=) |
| WO (1) | WO2012040177A1 (https=) |
| ZA (1) | ZA201301936B (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2812109A1 (en) * | 2010-09-20 | 2012-03-29 | Kareus Therapeutics, Sa | Methods and compositions for treatment of diabetes and dyslipidemia |
| US20140121267A1 (en) * | 2011-09-20 | 2014-05-01 | Kareus Therapeutics, Sa | Methods and compositions for treatment of diabetes and dyslipidemia |
| WO2014162320A2 (en) * | 2013-04-04 | 2014-10-09 | Sphaera Pharma Pvt. Ltd. | Novel analogues of epicatechin and related polyphenols |
| US9827222B2 (en) | 2013-07-01 | 2017-11-28 | Emory University | Treating or preventing nephrogenic diabetes insipidus |
| WO2015143276A1 (en) * | 2014-03-20 | 2015-09-24 | Esperion Therapeutics, Inc. | Carboxy-cyclopropyl undecanol compounds for treatment of liver disease and other medical disorders |
| RU2022102472A (ru) | 2015-03-13 | 2022-03-15 | Эсперион Терапеутикс, Инк. | Фиксированные комбинации и составы, содержащие etc-1002 и эзетимиб, и способы лечения или уменьшения риска развития сердечно-сосудистого заболевания |
| MA41793A (fr) | 2015-03-16 | 2018-01-23 | Esperion Therapeutics Inc | Associations de doses fixes comprenant du etc1002 et une ou plusieurs statines permettant de traiter ou de réduire un risque cardiovasculaire |
| CN107118098B (zh) * | 2016-02-25 | 2020-07-14 | 中国科学院上海药物研究所 | 一类脂肪酸类化合物、其制备方法及其用途 |
| PT3618821T (pt) * | 2017-01-31 | 2025-05-14 | Nephrodi Therapeutics Inc | Manejo da diabetes insípida nefrogénica |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3280169A (en) * | 1962-09-18 | 1966-10-18 | Union Carbide Corp | Sulfo-substituted aromatic dicarboxylic compounds |
| US3773946A (en) | 1969-09-02 | 1973-11-20 | Parke Davis & Co | Triglyceride-lowering compositions and methods |
| US3853951A (en) * | 1971-07-14 | 1974-12-10 | American Cyanamid Co | Preparation of 9-oxo-13-trans-prostenoic acid esters by alanate addition to cyclopentenone |
| IL64542A0 (en) | 1981-12-15 | 1982-03-31 | Yissum Res Dev Co | Long-chain alpha,omega-dicarboxylic acids and derivatives thereof and pharmaceutical compositions containing them |
| DE3423166A1 (de) | 1984-06-22 | 1986-01-02 | Epis S.A., Zug | Alpha-, omega-dicarbonsaeuren, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
| US4739113A (en) * | 1986-05-30 | 1988-04-19 | Merck & Co., Inc. | Bis(cyclopropanecarboxamido)alkadienedioic acids as renal dipeptidase inhibitors |
| JPS63246351A (ja) * | 1987-04-02 | 1988-10-13 | Rikagaku Kenkyusho | ポリケト−ル系化合物及びその合成法 |
| US5648387A (en) | 1995-03-24 | 1997-07-15 | Warner-Lambert Company | Carboxyalkylethers, formulations, and treatment of vascular diseases |
| FR2740135B1 (fr) | 1995-10-20 | 1997-12-19 | Roussel Uclaf | Nouveaux derives de pyrazoles acides, leur procede de preparation, leur application a titre de medicaments, leur nouvelle utilisation et les compositions pharmaceutiques les renfermant |
| IL119971A (en) | 1997-01-07 | 2003-02-12 | Yissum Res Dev Co | Pharmaceutical compositions containing dicarboxylic acids and derivatives thereof and some novel dicarboxylic acids |
| JPH10273469A (ja) * | 1997-02-03 | 1998-10-13 | Takeda Chem Ind Ltd | ２環性キノン誘導体、製造法および剤 |
| DE19837620A1 (de) | 1997-08-22 | 1999-02-25 | Novartis Ag | Organische Verbindungen |
| BRPI9909191B8 (pt) | 1998-03-27 | 2021-07-06 | Janssen Pharmaceutica Nv | derivados de pirimidina inibidores do hiv, seu uso e composição farmacêutica que os compreende |
| CZ299380B6 (cs) | 1998-03-27 | 2008-07-09 | Janssen Pharmaceutica N. V. | Pyrimidinová sloucenina, použití této slouceniny pro prípravu léciva, farmaceutický prostredek tutoslouceninu obsahující, zpusob prípravy tohoto prostredku a uvedené slouceniny a kombinace a produktuvedenou slouceninu obsahující |
| US6387897B1 (en) | 1998-06-30 | 2002-05-14 | Neuromed Technologies, Inc. | Preferentially substituted calcium channel blockers |
| AU769260B2 (en) | 1998-10-07 | 2004-01-22 | Georgetown University | Monomeric and dimeric heterocycles, and therapeutic uses thereof |
| EP1130469A1 (en) | 2000-02-22 | 2001-09-05 | Lucent Technologies Inc. | A radiation-sensitive resist material and a process for device fabrication using the same |
| DE10010430A1 (de) | 2000-03-03 | 2001-09-06 | Bayer Ag | Substituierte 5-Ethyl-dihydropyridazinone und ihre Verwendung |
| WO2002030860A2 (en) | 2000-10-11 | 2002-04-18 | Esperion Therapeutics, Inc. | Ketone compounds and compositions for cholesterol management and related uses |
| US6905525B2 (en) | 2001-04-02 | 2005-06-14 | Ciba Specialty Chemicals Corporation | Candle wax stabilized with piperazinones |
| US6544305B2 (en) | 2001-04-02 | 2003-04-08 | Ciba Specialty Chemicals Corporation | Candle wax stabilized with piperazinones |
| US6540795B2 (en) | 2001-04-02 | 2003-04-01 | Ciba Specialty Chemicals Corporation | Candle wax stabilized with oxazolidines |
| US6544304B2 (en) | 2001-04-02 | 2003-04-08 | Ciba Specialty Chemicals Corporation | Candle wax stabilized with morpholinones |
| US6562084B2 (en) | 2001-04-02 | 2003-05-13 | Ciba Specialty Chemicals Corporation | Candle wax stabilized with piperazindiones |
| WO2002079313A1 (en) | 2001-04-02 | 2002-10-10 | Ciba Specialty Chemicals Holding Inc. | Stabilized candle wax |
| US6547840B2 (en) | 2001-04-02 | 2003-04-15 | Ciba Specialty Chemicals Corporation | Candle wax stabilized with imidazolidines |
| US7375115B2 (en) * | 2001-10-09 | 2008-05-20 | Kyorin Pharmaceutical Co., Ltd. | 4-(2-furoyl) aminopiperidines, intermediates in synthesizing the same, process for producing the same and medicinal use of the same |
| US20040082641A1 (en) | 2002-10-28 | 2004-04-29 | Rytved Klaus Asger | Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases |
| HUE036646T2 (hu) | 2003-01-23 | 2018-07-30 | Esperion Therapeutics Inc | Hidroxilvegyületek és kompozícióik koleszterin szabályozására és kapcsolódó alkalmazásokra |
| JP2007525408A (ja) * | 2003-12-24 | 2007-09-06 | エスペリオン セラピューティクス，インコーポレイテッド | コレステロール管理および関連使用のためのケトン化合物および組成物 |
| AU2003300438A1 (en) | 2003-12-24 | 2005-08-03 | Esperion Therapeutics, Inc. | Ether compounds and compositions for cholesterol management and related uses |
| FR2903695B1 (fr) | 2006-07-13 | 2008-10-24 | Merck Sante Soc Par Actions Si | Utilisation de derives d'imidazole activateurs de l'ampk, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| IL181577A0 (en) * | 2007-02-26 | 2007-07-04 | Jacob Bar Tana | Combination therapy composition and methods for the treatment of cardiovascular disorders and immune-related disorders |
| JP5345293B2 (ja) | 2007-03-29 | 2013-11-20 | 株式会社Ａｄｅｋａ | 重合性化合物及び重合性組成物 |
| ATE530621T1 (de) | 2007-09-25 | 2011-11-15 | Merck Patent Gmbh | Mesogene dimere |
| CA2812109A1 (en) * | 2010-09-20 | 2012-03-29 | Kareus Therapeutics, Sa | Methods and compositions for treatment of diabetes and dyslipidemia |
-
2011
- 2011-09-20 CA CA2812109A patent/CA2812109A1/en not_active Abandoned
- 2011-09-20 EP EP11827340.8A patent/EP2618824A4/en not_active Withdrawn
- 2011-09-20 MX MX2013003078A patent/MX2013003078A/es not_active Application Discontinuation
- 2011-09-20 AU AU2011305610A patent/AU2011305610A1/en not_active Abandoned
- 2011-09-20 JP JP2013529411A patent/JP2013537240A/ja active Pending
- 2011-09-20 SG SG2013018833A patent/SG188996A1/en unknown
- 2011-09-20 RU RU2013118021/15A patent/RU2013118021A/ru not_active Application Discontinuation
- 2011-09-20 CN CN2011800558120A patent/CN103327974A/zh active Pending
- 2011-09-20 BR BR112013008675A patent/BR112013008675A2/pt not_active IP Right Cessation
- 2011-09-20 KR KR1020137007110A patent/KR20140009125A/ko not_active Withdrawn
- 2011-09-20 US US13/236,807 patent/US8623897B2/en active Active
- 2011-09-20 WO PCT/US2011/052318 patent/WO2012040177A1/en not_active Ceased
-
2013
- 2013-03-14 ZA ZA2013/01936A patent/ZA201301936B/en unknown
-
2014
- 2014-01-06 US US14/148,580 patent/US20140142178A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013537240A (ja) | 2013-09-30 |
| US20140142178A1 (en) | 2014-05-22 |
| BR112013008675A2 (pt) | 2016-06-21 |
| EP2618824A4 (en) | 2015-05-06 |
| CN103327974A (zh) | 2013-09-25 |
| KR20140009125A (ko) | 2014-01-22 |
| MX2013003078A (es) | 2013-09-26 |
| AU2011305610A1 (en) | 2013-03-14 |
| SG188996A1 (en) | 2013-05-31 |
| WO2012040177A1 (en) | 2012-03-29 |
| US20120071528A1 (en) | 2012-03-22 |
| EP2618824A1 (en) | 2013-07-31 |
| ZA201301936B (en) | 2014-05-28 |
| US8623897B2 (en) | 2014-01-07 |
| CA2812109A1 (en) | 2012-03-29 |
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