RU2011152518A - Применение композиции для лечения мукозита - Google Patents
Применение композиции для лечения мукозита Download PDFInfo
- Publication number
- RU2011152518A RU2011152518A RU2011152518/15A RU2011152518A RU2011152518A RU 2011152518 A RU2011152518 A RU 2011152518A RU 2011152518/15 A RU2011152518/15 A RU 2011152518/15A RU 2011152518 A RU2011152518 A RU 2011152518A RU 2011152518 A RU2011152518 A RU 2011152518A
- Authority
- RU
- Russia
- Prior art keywords
- composition
- specified
- range
- chitosan
- mucositis
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract 47
- 238000011282 treatment Methods 0.000 title claims abstract 6
- 229920001661 Chitosan Polymers 0.000 claims abstract 19
- 150000004676 glycans Chemical class 0.000 claims abstract 17
- 229920001282 polysaccharide Polymers 0.000 claims abstract 17
- 239000005017 polysaccharide Substances 0.000 claims abstract 17
- 206010028116 Mucosal inflammation Diseases 0.000 claims abstract 15
- 201000010927 Mucositis Diseases 0.000 claims abstract 15
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims abstract 7
- 229920000669 heparin Polymers 0.000 claims abstract 7
- 229960002897 heparin Drugs 0.000 claims abstract 7
- 229920002971 Heparan sulfate Polymers 0.000 claims abstract 4
- 241000124008 Mammalia Species 0.000 claims abstract 4
- 229960000633 dextran sulfate Drugs 0.000 claims abstract 4
- 230000006196 deacetylation Effects 0.000 claims abstract 3
- 238000003381 deacetylation reaction Methods 0.000 claims abstract 3
- 239000002518 antifoaming agent Substances 0.000 claims abstract 2
- 239000004599 antimicrobial Substances 0.000 claims abstract 2
- 238000000034 method Methods 0.000 claims 6
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 238000002512 chemotherapy Methods 0.000 claims 2
- 210000000214 mouth Anatomy 0.000 claims 2
- 238000001959 radiotherapy Methods 0.000 claims 2
- 238000009168 stem cell therapy Methods 0.000 claims 2
- 238000009580 stem-cell therapy Methods 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000002324 mouth wash Substances 0.000 claims 1
- 229940051866 mouthwash Drugs 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 238000011200 topical administration Methods 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/722—Chitin, chitosan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/721—Dextrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0950441-6 | 2009-06-10 | ||
| SE0950441 | 2009-06-10 | ||
| PCT/SE2010/050650 WO2010144044A1 (en) | 2009-06-10 | 2010-06-10 | Use of a composition for the treatment of mucositis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2011152518A true RU2011152518A (ru) | 2013-07-20 |
Family
ID=43309105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2011152518/15A RU2011152518A (ru) | 2009-06-10 | 2010-06-10 | Применение композиции для лечения мукозита |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8906883B2 (enExample) |
| EP (1) | EP2440216A4 (enExample) |
| JP (1) | JP2012529506A (enExample) |
| CN (1) | CN102458419A (enExample) |
| AU (1) | AU2010259284A1 (enExample) |
| BR (1) | BRPI1009741A2 (enExample) |
| CA (1) | CA2763092A1 (enExample) |
| RU (1) | RU2011152518A (enExample) |
| WO (1) | WO2010144044A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2555760B1 (en) | 2010-04-06 | 2019-10-16 | Synedgen, Inc. | Chitosan derivatives for the treatment of mucositis or ulceration |
| CA2883704C (en) | 2012-09-20 | 2021-09-28 | Synedgen, Inc. | Methods for treatment or prevention of damage resulting from radiation, trauma or shock |
| WO2015022907A1 (ja) * | 2013-08-13 | 2015-02-19 | 生化学工業株式会社 | カチオン化キトサンを含有する医薬 |
| EP3060243A4 (en) * | 2013-10-22 | 2017-03-29 | Cantex Pharmaceuticals, Inc. | Methods of treating and preventing radiation damage |
| US20180228832A1 (en) * | 2015-08-18 | 2018-08-16 | Pharma Seeds Create, Llc | Stomatological composition containing nsaid or heparin compound |
| EP3787593A1 (en) * | 2018-05-04 | 2021-03-10 | Bonoss Medical Aktiebolag | A composition for reduction of scar formation |
| WO2019236453A1 (en) | 2018-06-03 | 2019-12-12 | Glycomira Therapeutics, Inc. | Methods for preventing a serious health consequence and/or tissue damage after exposure to ionizing radiation and /or chemotherapy |
| US20230181624A1 (en) * | 2020-04-24 | 2023-06-15 | Intact Therapeutics, Inc. | Compositions and methods for treatment of gastrointestinal bleeding |
| EP3981505B1 (en) * | 2020-10-12 | 2024-11-27 | Gambro Lundia AB | Membrane with immobilized anticoagulant and process for producing same |
| EP4401784A4 (en) * | 2021-09-17 | 2025-09-10 | Shawn Walker | USE OF CHITOSAN COMPLEXES OR COMPOSITIONS TO REDUCE THE INFILTRATION OF ENVIRONMENTAL FACTORS INTO THE BRAIN |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9402529D0 (sv) * | 1994-07-19 | 1994-07-19 | Astra Ab | Anti-adherensmedel |
| SE9402531L (sv) * | 1994-07-19 | 1996-01-20 | Medicarb Ab | Sårläkningsmedel |
| SE507028C2 (sv) | 1996-08-06 | 1998-03-16 | Medicarb Ab | Ny medicinsk användning |
| US6989156B2 (en) * | 2001-04-23 | 2006-01-24 | Nucryst Pharmaceuticals Corp. | Therapeutic treatments using the direct application of antimicrobial metal compositions |
| US7547433B2 (en) * | 2001-02-15 | 2009-06-16 | Access Pharmaceuticals, Inc. | Liquid formulations for the prevention and treatment of mucosal diseases and disorders |
| EP1539192A1 (en) | 2002-04-24 | 2005-06-15 | Medicarb AB | Composition and kit for the treatment of inflammatory bowel diseases |
| JP2006508075A (ja) * | 2002-10-07 | 2006-03-09 | オラファーマ， インコーポレイテッド | 粘膜付着性テトラサイクリン製剤 |
| AU2005285040A1 (en) * | 2004-09-14 | 2006-03-23 | Molecular Therapeutics, Inc. | D-methionine formulation with improved biopharmaceutical properties |
| US20080118542A1 (en) | 2005-01-19 | 2008-05-22 | Bonoss Medical Ab | Growth Factor Composition |
| DE102006024831B4 (de) | 2006-05-24 | 2008-03-27 | Heraeus Quarzglas Gmbh & Co. Kg | Verfahren zur Herstellung eines Halbzeugs aus synthetischem Quarzglas |
| US20080299050A1 (en) | 2006-10-05 | 2008-12-04 | Drugtech Corporation | Topical therapies for oral mucositis and other conditions |
-
2010
- 2010-06-10 RU RU2011152518/15A patent/RU2011152518A/ru not_active Application Discontinuation
- 2010-06-10 CA CA2763092A patent/CA2763092A1/en not_active Abandoned
- 2010-06-10 EP EP10786461.3A patent/EP2440216A4/en not_active Withdrawn
- 2010-06-10 WO PCT/SE2010/050650 patent/WO2010144044A1/en not_active Ceased
- 2010-06-10 AU AU2010259284A patent/AU2010259284A1/en not_active Abandoned
- 2010-06-10 CN CN2010800254173A patent/CN102458419A/zh active Pending
- 2010-06-10 JP JP2012514923A patent/JP2012529506A/ja active Pending
- 2010-06-10 BR BRPI1009741A patent/BRPI1009741A2/pt not_active IP Right Cessation
- 2010-06-10 US US13/376,947 patent/US8906883B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI1009741A2 (pt) | 2016-03-15 |
| CN102458419A (zh) | 2012-05-16 |
| WO2010144044A1 (en) | 2010-12-16 |
| AU2010259284A1 (en) | 2011-12-15 |
| JP2012529506A (ja) | 2012-11-22 |
| EP2440216A4 (en) | 2013-09-11 |
| CA2763092A1 (en) | 2010-12-16 |
| US8906883B2 (en) | 2014-12-09 |
| EP2440216A1 (en) | 2012-04-18 |
| US20120077773A1 (en) | 2012-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA94 | Acknowledgement of application withdrawn (non-payment of fees) |
Effective date: 20150716 |