RU2011128680A - Механизм привода для устройства подачи лекарственного средства и устройство подачи лекарственного средства - Google Patents

Механизм привода для устройства подачи лекарственного средства и устройство подачи лекарственного средства Download PDF

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Publication number
RU2011128680A
RU2011128680A RU2011128680/14A RU2011128680A RU2011128680A RU 2011128680 A RU2011128680 A RU 2011128680A RU 2011128680/14 A RU2011128680/14 A RU 2011128680/14A RU 2011128680 A RU2011128680 A RU 2011128680A RU 2011128680 A RU2011128680 A RU 2011128680A
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Russia
Prior art keywords
rotation
drive
relative
drive mechanism
housing
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RU2011128680/14A
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English (en)
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RU2515867C2 (ru
Inventor
Филипп НЦИКЕ
Штеффен РААБ
Ульрих БРЮГГЕМАНН
Уве ДАСБАХ
Уве БЕЗЕР
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Санофи-Авентис Дойчланд Гмбх
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44318334&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU2011128680(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Санофи-Авентис Дойчланд Гмбх filed Critical Санофи-Авентис Дойчланд Гмбх
Priority claimed from PCT/EP2009/066742 external-priority patent/WO2010066796A1/en
Publication of RU2011128680A publication Critical patent/RU2011128680A/ru
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16H—GEARING
    • F16H25/00—Gearings comprising primarily only cams, cam-followers and screw-and-nut mechanisms
    • F16H25/18—Gearings comprising primarily only cams, cam-followers and screw-and-nut mechanisms for conveying or interconverting oscillating or reciprocating motions
    • F16H25/20—Screw mechanisms
    • F16H25/2015—Means specially adapted for stopping actuators in the end position; Position sensing means
    • A—HUMAN NECESSITIES
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    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
    • A—HUMAN NECESSITIES
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    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/31581—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by rotationally moving or pivoting actuator operated by user, e.g. an injection lever or handle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16H—GEARING
    • F16H25/00—Gearings comprising primarily only cams, cam-followers and screw-and-nut mechanisms
    • F16H25/08—Gearings comprising primarily only cams, cam-followers and screw-and-nut mechanisms for interconverting rotary motion and reciprocating motion
    • F16H25/12—Gearings comprising primarily only cams, cam-followers and screw-and-nut mechanisms for interconverting rotary motion and reciprocating motion with reciprocation along the axis of rotation, e.g. gearings with helical grooves and automatic reversal or cams
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16H—GEARING
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    • F16H25/18—Gearings comprising primarily only cams, cam-followers and screw-and-nut mechanisms for conveying or interconverting oscillating or reciprocating motions
    • F16H25/20—Screw mechanisms
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
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    • A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31561—Mechanically operated dose setting member using freely adjustable volume steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/3157—Means providing feedback signals when administration is completed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31573—Accuracy improving means
    • A61M5/31575—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T74/00—Machine element or mechanism
    • Y10T74/18—Mechanical movements
    • Y10T74/18568—Reciprocating or oscillating to or from alternating rotary
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T74/00—Machine element or mechanism
    • Y10T74/18—Mechanical movements
    • Y10T74/18568—Reciprocating or oscillating to or from alternating rotary
    • Y10T74/18576—Reciprocating or oscillating to or from alternating rotary including screw and nut
    • Y10T74/18696—Reciprocating or oscillating to or from alternating rotary including screw and nut including means to selectively transmit power [e.g., clutch, etc.]

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Abstract

1. Механизм привода для устройства (1) подачи лекарственного средства, содержащий:- корпус (13, 17, 40), имеющий проксимальный конец и дистальный конец,- элемент (21) вращения, выполненный с возможностью вращения в первом направлении относительно корпуса во время установки дозы лекарственного средства (5) и с возможностью вращения во втором направлении относительно корпуса во время подачи дозы, причем второе направление противоположно первому направлению,- шток (12) поршня, выполненный с возможностью перемещения в дистальном направлении относительно корпуса для подачи дозы,- элемент (20) привода, который следует за вращательным движением элемента вращения во втором направлении во время подачи дозы, и- элемент (26) остановки, предотвращающий вращательное движение элемента привода относительно корпуса в первом направлении во время установки дозы,в котором- вращательное движение элемента привода во втором направлении преобразуется в перемещение штока поршня в дистальном направлении относительно корпуса.2. Механизм привода по п.1,в котором механизм привода содержит дозирующий элемент (16, 34, 41), который может двигаться относительно корпуса (13, 17, 40) во время установки и подачи дозы и в котором движение дозирующего элемента относительно корпуса преобразуется во вращательное движение элемента вращения относительно корпуса.3. Механизм привода по п.2,в котором дозирующий элемент (16, 34, 41) крепится, не допуская его вращательного движения относительно корпуса (13, 17, 40).4. Механизм привода, по любому одному из предшествующих пунктов,в котором элемент (20) привода и элемент (21) вращения могут вращаться вокруг общей оси вращения.5. Механизм

Claims (16)

1. Механизм привода для устройства (1) подачи лекарственного средства, содержащий:
- корпус (13, 17, 40), имеющий проксимальный конец и дистальный конец,
- элемент (21) вращения, выполненный с возможностью вращения в первом направлении относительно корпуса во время установки дозы лекарственного средства (5) и с возможностью вращения во втором направлении относительно корпуса во время подачи дозы, причем второе направление противоположно первому направлению,
- шток (12) поршня, выполненный с возможностью перемещения в дистальном направлении относительно корпуса для подачи дозы,
- элемент (20) привода, который следует за вращательным движением элемента вращения во втором направлении во время подачи дозы, и
- элемент (26) остановки, предотвращающий вращательное движение элемента привода относительно корпуса в первом направлении во время установки дозы,
в котором
- вращательное движение элемента привода во втором направлении преобразуется в перемещение штока поршня в дистальном направлении относительно корпуса.
2. Механизм привода по п.1,
в котором механизм привода содержит дозирующий элемент (16, 34, 41), который может двигаться относительно корпуса (13, 17, 40) во время установки и подачи дозы и в котором движение дозирующего элемента относительно корпуса преобразуется во вращательное движение элемента вращения относительно корпуса.
3. Механизм привода по п.2,
в котором дозирующий элемент (16, 34, 41) крепится, не допуская его вращательного движения относительно корпуса (13, 17, 40).
4. Механизм привода, по любому одному из предшествующих пунктов,
в котором элемент (20) привода и элемент (21) вращения могут вращаться вокруг общей оси вращения.
5. Механизм привода по п.4,
в котором шток (12) поршня перемещается в дистальном направлении относительно корпуса (13, 17, 40) вдоль оси вращения или в котором шток (12) поршня перемещается в дистальном направлении относительно корпуса (13, 17, 40) поперек оси вращения.
6. Механизм привода, по любому одному из пп.1-3,
в котором элемент (20) привода устанавливается между элементом (26) остановки и элементом (21) вращения.
7. Механизм привода по п.2 или 3,
в котором дозирующий элемент (16, 34, 41) и элемент (21) вращения находятся в резьбовом зацеплении.
8. Механизм привода по п.2 или 3,
в котором дозирующий элемент (16, 34, 41) и элемент (21) вращения (21) соединены друг с другом рычагом (55), причем рычаг шарнирно вращается вокруг оси вращения во время движения дозирующего элемента для установки и подачи дозы.
9. Механизм привода, по любому одному из пп.1-3,
в котором элемент (20) привода и элемент (21) вращения соединяются друг с другом первым однонаправленным механизмом фрикционного зажимного устройства, выполненным с возможностью разрешения относительного вращательного движения между элементом вращения и элементом привода во время вращения элемента вращения в первом направлении для установки дозы и предотвращения относительного вращательного движения элемента вращения и элемента привода во время вращения элемента вращения во втором направлении для подачи дозы.
10. Механизм привода, по любому одному из пп.1-3,
в котором элемент (20) привода и элемент (26) остановки соединяются друг с другом вторым однонаправленным механизмом фрикционного зажимного устройства, выполненным с возможностью предотвращения относительного вращательного движения между элементом остановки и элементом привода во время вращения элемента (21) вращения в первом направлении для установки дозы и разрешения относительного вращательного движения элемента остановки и элемента привода во время вращения элемента вращения во втором направлении для подачи дозы.
11. Механизм привода, по любому одному из пп.1-3,
в котором элемент (26) остановки крепится, не допуская вращательного движения относительно корпуса (13, 17, 40).
12. Механизм привода, по любому одному из пп.1-3,
в котором элемент (26) остановки может двигаться в осевом направлении относительно корпуса (13, 17, 40).
13. Механизм привода, по любому одному из пп.1-3,
в котором
- элемент (21) вращения выполнен с возможностью вращения в первом направлении вокруг оси вращения,
- элемент привода содержит зубчатое зацепление (22) со множеством зубьев (24) и элемент вращения содержит зубчатое зацепление (23) со множеством зубьев (25), в котором зубчатое зацепление элемента привода сопрягается с зубчатым зацеплением элемента вращения, и зубья зубчатого зацепления элемента вращения и зубья зубчатого зацепления элемента привода располагаются вдоль оси вращения,
- элемент привода упирается в элемент остановки и элемент вращения во время движения элемента вращения для установки и подачи дозы, и
- элемент вращения и элемент остановки поддерживаются в состоянии упора в элемент привода силой, обеспечиваемой элементом (31) пружины во время установки и подачи дозы.
14. Механизм привода по п.13,
в котором элемент (26) остановки имеет зубчатое зацепление (27), и элемент (20) привода имеет дополнительное зубчатое зацепление (28), причем зубчатое зацепление (22) элемента привода и дополнительное зубчатое зацепление элемента привода располагаются противоположно.
15. Механизм привода по п.13,
в котором зубья соответствующего зубчатого соединения имеют пилообразную форму.
16. Устройство (1) подачи лекарственного средства, содержащее механизм привода, по любому одному из пп. 1-3, и картридж (4), причем картридж содержит множество доз лекарственного средства (5).
RU2011128680/14A 2008-12-12 2009-12-09 Механизм привода для устройства подачи лекарственного средства и устройство подачи лекарственного средства RU2515867C2 (ru)

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EP08021628A EP2196232A1 (en) 2008-12-12 2008-12-12 Drive mechanism for a medication delivery device and medication delivery device
US12/333,459 US8840591B2 (en) 2008-12-12 2008-12-12 Drive mechanism for a medication delivery device and medication delivery device
EP08021628.6 2008-12-12
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US20160001008A1 (en) 2016-01-07
CN102281910A (zh) 2011-12-14
US20150174332A1 (en) 2015-06-25
MY155197A (en) 2015-09-15
SG172112A1 (en) 2011-07-28
TW201026349A (en) 2010-07-16
RU2515867C2 (ru) 2014-05-20
IL213383A0 (en) 2011-07-31
NZ593301A (en) 2012-11-30
EP2196232A1 (en) 2010-06-16
IL213383A (en) 2014-12-31
EP2926850A1 (en) 2015-10-07
US20100152671A1 (en) 2010-06-17
JP5599406B2 (ja) 2014-10-01
AU2009324405B2 (en) 2014-10-09
EP3335749A1 (en) 2018-06-20
AU2009324405A1 (en) 2011-06-30
US9539396B2 (en) 2017-01-10
DK3335749T3 (da) 2020-01-06
US9457152B2 (en) 2016-10-04
US8840591B2 (en) 2014-09-23
DE202009019077U1 (de) 2016-04-08
TR201810016T4 (tr) 2018-09-21
EP2926850B1 (en) 2018-04-18
EP3335749B1 (en) 2019-10-09
KR20110099030A (ko) 2011-09-05
DK2376148T3 (en) 2018-07-23
TR201809841T4 (tr) 2018-09-21
CN102281910B (zh) 2014-08-20
JP2012511358A (ja) 2012-05-24
DK2926850T3 (en) 2018-07-30
MX2011005879A (es) 2011-06-27
CA2746014A1 (en) 2010-06-17
ZA201103707B (en) 2012-01-25

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