RU2011123582A - METHOD FOR PRODUCING 3- (o-, m-, p-METHOXYPHENYL) -TETRAHYDRO-2H-1, 5, 3-DIOXAZEPINES - Google Patents

METHOD FOR PRODUCING 3- (o-, m-, p-METHOXYPHENYL) -TETRAHYDRO-2H-1, 5, 3-DIOXAZEPINES Download PDF

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RU2011123582A
RU2011123582A RU2011123582/04A RU2011123582A RU2011123582A RU 2011123582 A RU2011123582 A RU 2011123582A RU 2011123582/04 A RU2011123582/04 A RU 2011123582/04A RU 2011123582 A RU2011123582 A RU 2011123582A RU 2011123582 A RU2011123582 A RU 2011123582A
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dioxazepines
tetrahydro
methoxyphenyl
methoxyaniline
ethanediol
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RU2011123582/04A
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RU2478096C2 (en
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Усеин Меметович Джемилев
Наталия Наильевна Мурзакова
Кирилл Игоревич Прокофьев
Внира Рахимовна Ахметова
Асхат Габдрахманович Ибрагимов
Любовь Фёдоровна Коржова
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Учреждение Российской Академии Наук Институт Нефтехимии И Катализа Ран
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Abstract

Способ получения 3-(о-,м-,п-метоксифенил)-тетрагидро-2Н-1,5,3-диоксазепинов общей формулы (1):отличающийся тем, что к предварительно полученной при 20°С в течение 30 мин смеси формальдегида с 1,2-этандиолом добавляют катализатор Sm(NO)·6HO, о-(или м-, или n-)метоксианилин при мольном соотношении о-(или м-, или n-)метоксианилин:формальдегид:1,2-этандиол:Sm(NO)·6HO=10:20:10:0.5, с последующим перемешиванием при комнатной (~20°С) температуре в течение 50-70 мин в хлороформе.The method of obtaining 3- (o-, m-, p-methoxyphenyl) -tetrahydro-2H-1,5,3-dioxazepines of the general formula (1): characterized in that to the formaldehyde mixture previously obtained at 20 ° C for 30 minutes Sm (NO) 6HO, o- (or m-, or n-) methoxyaniline is added with 1,2-ethanediol at a molar ratio of o- (or m-, or n-) methoxyaniline: formaldehyde: 1,2-ethanediol : Sm (NO) 6HO = 10: 20: 10: 0.5, followed by stirring at room temperature (~ 20 ° С) for 50-70 min in chloroform.

Claims (1)

Способ получения 3-(о-,м-,п-метоксифенил)-тетрагидро-2Н-1,5,3-диоксазепинов общей формулы (1):The method of obtaining 3- (o-, m-, p-methoxyphenyl) -tetrahydro-2H-1,5,3-dioxazepines of the general formula (1):
Figure 00000001
Figure 00000001
 отличающийся тем, что к предварительно полученной при 20°С в течение 30 мин смеси формальдегида с 1,2-этандиолом добавляют катализатор Sm(NO3)3·6H2O, о-(или м-, или n-)метоксианилин при мольном соотношении о-(или м-, или n-)метоксианилин:формальдегид:1,2-этандиол:Sm(NO3)3·6H2O=10:20:10:0.5, с последующим перемешиванием при комнатной (~20°С) температуре в течение 50-70 мин в хлороформе. characterized in that a catalyst Sm (NO 3 ) 3 · 6H 2 O, o- (or m-, or n-) methoxyaniline is added to a mixture of formaldehyde with 1,2-ethanediol preliminarily obtained for 30 minutes the ratio of o- (or m-, or n-) methoxyaniline: formaldehyde: 1,2-ethanediol: Sm (NO 3 ) 3 · 6H 2 O = 10: 20: 10: 0.5, followed by stirring at room temperature (~ 20 ° C) temperature for 50-70 minutes in chloroform.
RU2011123582/04A 2011-06-09 2011-06-09 METHOD OF PRODUCING 3-(o-,m-,n-METHOXYPHENYL)-TETRAHYDRO-2H-1,3,3-DIOXAZEPINES RU2478096C2 (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
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RU2605445C1 (en) * 2015-06-10 2016-12-20 Федеральное государственное бюджетное учреждение науки Институт нефтехимии и катализа Российской академии наук Method for production of 10-halophenyl-7,8,12,13-tetraoxa-10-azaspiro[5_7]tridecanes

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RU2584950C1 (en) * 2014-12-11 2016-05-20 Федеральное государственное бюджетное учреждение науки Институт нефтехимии и катализа Российской академии наук Method of producing 10-aryl-7,8,12,13-tetraoxa-10-aza-spiro[5,7]tridecanes

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RU2002123631A (en) * 2002-09-04 2004-03-20 ГУ Институт нефтехимии и катализа АН РБ и УНЦ РАН METHOD FOR PRODUCING 5- [ORTO- (META-, PARA-) METHOXYPHENYL] -1,3,5-Dithiazines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2605445C1 (en) * 2015-06-10 2016-12-20 Федеральное государственное бюджетное учреждение науки Институт нефтехимии и катализа Российской академии наук Method for production of 10-halophenyl-7,8,12,13-tetraoxa-10-azaspiro[5_7]tridecanes

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