RU2009145011A - NEW APPLICATION OF THE MEDICINAL COMPOSITION OF CHINESE MEDICINE - Google Patents

NEW APPLICATION OF THE MEDICINAL COMPOSITION OF CHINESE MEDICINE Download PDF

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RU2009145011A
RU2009145011A RU2009145011/15A RU2009145011A RU2009145011A RU 2009145011 A RU2009145011 A RU 2009145011A RU 2009145011/15 A RU2009145011/15 A RU 2009145011/15A RU 2009145011 A RU2009145011 A RU 2009145011A RU 2009145011 A RU2009145011 A RU 2009145011A
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bark
filtered
solution
pharmaceutical composition
composition according
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Илинг Ву (Cn)
Илинг ВУ
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Хебей Илинг Медисин Рисоч Инститьют Ко. Лтд. (Китай) (Cn)
Хебей Илинг Медисин Рисоч Инститьют Ко. Лтд. (Китай)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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Abstract

1. Фармацевтическая композиция для лечения кардиомиопатии, приготовленная из сырьевых лекарственных материалов, взятых при следующем массовом соотношении, мас.ч.: ! Астрагал 150-450 Аконит 40-120 Женьшень или коволосистый кодонопсис 75-225 Шалфей многокорневищный 75-225 Быльник 50-150 Кора обвойника или кора шиповатого акантопанакса 60-180 Частуха 75-225 Растение ючжу 25-75 Корица 30-90Сафлон 30-90 Кора мандарина 25-75 ! 2. Фармацевтическая композиция по п.1, отличающаяся тем, что приготовлена из названных сырьевых лекарственных материалов, взятых при следующем массовом соотношении, мас.ч.: ! Астрагал 450 Аконит 112,5 Женьшень или коволосистый кодонопсис 225 Шалфей многокорневищный 225 Быльник 150 Кора обвойника или кора шиповатого акантопанакса 180 Частуха 225 Растение ючжу 75 Корица 90 Сафлон 90 Кора мандарина 75 ! 3. Способ приготовления фармацевтической композиции по любому из пп.1 и 2, включающий следующие стадии: ! 1) экстракция астрагала, быльника, частухи, женьшеня или коволосистого кодонопсиса, коры обвойника или коры шиповатого акантопанакса 70% этиловым спиртом, полученный экстрагированный раствор фильтруют и выпаривают до получения помады с относительной плотностью 1,25-1,30 при температуре 50-70°С; ! 2) экстракция водой нафты из корицы и коры мандарина до получения нафты А, водяного раствора В и остатков С; ! 3) фильтрация остаточного водяного раствора В до получения раствора Е, добавление воды в остатки С, которые варят и фильтруют до получения раствора F; ! 4) варят в воде аконит, шалфей многокорневищный, растение ючжу, сафлон, полученный водный раствор фильтруют до получения раствора D; ! 5) смешивают отфильтрованн� 1. The pharmaceutical composition for the treatment of cardiomyopathy, prepared from raw medicinal materials taken in the following weight ratio, parts by weight:! Astragalus 150-450 Aconite 40-120 Ginseng or kovolosodny codonopsis 75-225 Sage multi-rhizome 75-225 Almonds 50-150 Bark of an obohnik or bark of a prickly acanthopanax 60-180 Chastuha 75-225 Plant yuzhu 25-75 Cinnamon 30-90 Cafflon 30-90 Bark tangerine 25-75! 2. The pharmaceutical composition according to claim 1, characterized in that it is prepared from the named raw medicinal materials taken in the following weight ratio, parts by weight:! Astragalus 450 Aconite 112.5 Ginseng or kovolosodny codonopsis 225 Sage multi-rhizome 225 Epiphany 150 Bark of an upholstered or bark of a prickly acanthopanax 180 Chastukha 225 Plant yuzhu 75 Cinnamon 90 Safflon 90 Bark of mandarin 75! 3. A method of preparing a pharmaceutical composition according to any one of claims 1 and 2, comprising the following steps:! 1) extraction of astragalus, birch bark, gibberish, ginseng or kovolosovy codonopsis, cortex of the fennel or bark of prickly acanthopanax with 70% ethanol, the resulting extracted solution is filtered and evaporated to obtain lipstick with a relative density of 1.25-1.30 at a temperature of 50-70 ° FROM; ! 2) water extraction of naphtha from cinnamon and mandarin bark to obtain naphtha A, aqueous solution B and residues C; ! 3) filtering the residual aqueous solution B to obtain a solution E, adding water to residues C, which are boiled and filtered to obtain a solution F; ! 4) aconite is boiled in water, sage is multi-rhizome, yuzhu plant, safflon, the resulting aqueous solution is filtered to obtain a solution of D; ! 5) mix filtered

Claims (11)

1. Фармацевтическая композиция для лечения кардиомиопатии, приготовленная из сырьевых лекарственных материалов, взятых при следующем массовом соотношении, мас.ч.:1. The pharmaceutical composition for the treatment of cardiomyopathy, prepared from raw medicinal materials taken in the following weight ratio, parts by weight: АстрагалAstragalus 150-450150-450 АконитAconite 40-12040-120 Женьшень или коволосистый кодонопсисGinseng or Hairy Codonopsis 75-22575-225 Шалфей многокорневищныйSage multi-root 75-22575-225 БыльникBilnik 50-15050-150 Кора обвойника или кора шиповатого акантопанаксаAcornopanax bark or barbed bark 60-18060-180 ЧастухаChastuha 75-22575-225 Растение ючжуYuzhu plant 25-7525-75 КорицаCinnamon 30-9030-90 СафлонSafflon 30-9030-90 Кора мандаринаMandarin Bark 25-7525-75
2. Фармацевтическая композиция по п.1, отличающаяся тем, что приготовлена из названных сырьевых лекарственных материалов, взятых при следующем массовом соотношении, мас.ч.:2. The pharmaceutical composition according to claim 1, characterized in that it is prepared from the named raw medicinal materials taken in the following weight ratio, parts by weight: АстрагалAstragalus 450450 АконитAconite 112,5112.5 Женьшень или коволосистый кодонопсисGinseng or Hairy Codonopsis 225225 Шалфей многокорневищныйSage multi-root 225225 БыльникBilnik 150150 Кора обвойника или кора шиповатого акантопанаксаAcornopanax bark or barbed bark 180180 ЧастухаChastuha 225225 Растение ючжуYuzhu plant 7575 КорицаCinnamon 9090 СафлонSafflon 9090 Кора мандаринаMandarin Bark 7575
3. Способ приготовления фармацевтической композиции по любому из пп.1 и 2, включающий следующие стадии:3. A method of preparing a pharmaceutical composition according to any one of claims 1 and 2, comprising the following steps: 1) экстракция астрагала, быльника, частухи, женьшеня или коволосистого кодонопсиса, коры обвойника или коры шиповатого акантопанакса 70% этиловым спиртом, полученный экстрагированный раствор фильтруют и выпаривают до получения помады с относительной плотностью 1,25-1,30 при температуре 50-70°С;1) extraction of astragalus, bilberry, bark, ginseng or kovonosodnogo codonopsis, bark obvnika or bark of prickly acantopanax 70% ethanol, the resulting extracted solution is filtered and evaporated to obtain lipstick with a relative density of 1.25-1.30 at a temperature of 50-70 ° FROM; 2) экстракция водой нафты из корицы и коры мандарина до получения нафты А, водяного раствора В и остатков С;2) water extraction of naphtha from cinnamon and mandarin bark to obtain naphtha A, aqueous solution B and residues C; 3) фильтрация остаточного водяного раствора В до получения раствора Е, добавление воды в остатки С, которые варят и фильтруют до получения раствора F;3) filtering the residual aqueous solution B to obtain a solution E, adding water to residues C, which are boiled and filtered to obtain a solution F; 4) варят в воде аконит, шалфей многокорневищный, растение ючжу, сафлон, полученный водный раствор фильтруют до получения раствора D;4) aconite is boiled in water, sage is multi-rhizome, yuzhu plant, safflon, the resulting aqueous solution is filtered to obtain a solution of D; 5) смешивают отфильтрованные водные растворы D, Е и F и при перемешивании добавляют этиловый спирт до получения концентрации спирта в растворе, равной 60-80%, настаивают, фильтруют и выпаривают отфильтрованный раствор до получения помады G с относительной плотностью 1,25-1,30 при температуре 60-70°С;5) the filtered aqueous solutions of D, E and F are mixed and ethanol is added with stirring to obtain an alcohol concentration of 60-80% in the solution, insisted, filtered and the filtered solution is evaporated to obtain lipstick G with a relative density of 1.25-1, 30 at a temperature of 60-70 ° C; 6) из полученных помады на стадии 1), нафты А и помады G на стадии 5) готовят лекарственные препараты в формах, приемлемых в клинической практике.6) from the lipstick obtained in stage 1), naphtha A and lipstick G in stage 5), drugs are prepared in forms acceptable in clinical practice. 4. Способ приготовления фармацевтической композиции по любому из пп.1 и 2, характеризующийся следующими стадиями:4. A method of preparing a pharmaceutical composition according to any one of claims 1 and 2, characterized by the following stages: 1) экстрагируют астрагал, быльник, частуху, женьшень или коволосистый кодонопсис, кору обвойника или кору шиповатого акантопанакса 70% этиловым спиртом, полученный экстрагированный раствор фильтруют и выпаривают до получения помады с относительной плотностью 1,25-1,30 при температуре 60°С;1) extraction of astragalus, bilberry, bark, ginseng or kovolosovy codonopsis, bark of the obochnik or bark of prickly acantopanax with 70% ethyl alcohol, the resulting extracted solution is filtered and evaporated to obtain lipstick with a relative density of 1.25-1.30 at a temperature of 60 ° C; 2) экстрагируют нафту из корицы и коры мандарина;2) extract naphtha from cinnamon and mandarin bark; 3) варят аконит, шалфей многокорневищный, растение ючжу, сафлон в воде, фильтруют полученный водный раствор; после экстракции нафты из корицы и коры мандарина фильтруют остаточный водный раствор, получают отфильтрованный водный раствор и остатки; добавляют воду в остатки и варят, фильтрируют, после чего полученные вышеприведенные водяные растворы смешивают и во время перемешивания добавляют этиловый спирт до того, что концентрация спирта составляет 70%, настаивают, фильтруют, отфильтрованный раствор выпаривают до того, что до того, что получается помада с относительной плотностью 1,25-1,30 при температуре 60°С.3) boil aconite, sage, multi-rhizome, yuzhu plant, safflon in water, filter the resulting aqueous solution; after extraction of naphtha from cinnamon and mandarin bark, the residual aqueous solution is filtered, a filtered aqueous solution and residues are obtained; water is added to the residues and boiled, filtered, after which the resulting above aqueous solutions are mixed and ethanol is added to the mixture until the alcohol concentration is 70%, insisted, filtered, the filtered solution is evaporated until the lipstick is obtained with a relative density of 1.25-1.30 at a temperature of 60 ° C. 5. Способ приготовления фармацевтической композиции по п.3, характеризующийся тем, что получают лекарственные формы, приемлемые в клинической практике, такие как капсула, таблетка, сыпучий компонент, порошковой компонент, пероральный раствор или пилюля.5. The method of preparing the pharmaceutical composition according to claim 3, characterized in that they obtain dosage forms acceptable in clinical practice, such as a capsule, tablet, granular component, powder component, oral solution or pill. 6. Способ приготовления фармацевтической композиции по п.4, характеризующийся тем, что получают лекарственные формы, приемлемые в клинической практике, такие как капсула, таблетка, сыпучий компонент, порошковой компонент, пероральный раствор или пилюля.6. The method of preparing the pharmaceutical composition according to claim 4, characterized in that the dosage form is acceptable, which is acceptable in clinical practice, such as a capsule, tablet, granular component, powder component, oral solution or pill. 7. Применение фармацевтической композиции по любому из пп.1 и 2 для приготовления лекарственного препарата для лечения кардиомиопатии, например дилатационной кардиомиопатии.7. The use of the pharmaceutical composition according to any one of claims 1 and 2 for the preparation of a medicament for the treatment of cardiomyopathy, for example dilated cardiomyopathy. 8. Применение фармацевтической композиции по любому из пп.1 и 2 для приготовления лекарственного препарата для лечения хронической сердечной недостаточности из-за дилатационной кардиомиопатии.8. The use of the pharmaceutical composition according to any one of claims 1 and 2 for the preparation of a medicament for the treatment of chronic heart failure due to dilated cardiomyopathy. 9. Применение фармацевтической композиции по любому из пп.1 и 2 для приготовления лекарственного препарата для уменьшения концентрации мозгового натрийуретического пептида в плазме.9. The use of the pharmaceutical composition according to any one of claims 1 and 2 for the preparation of a medicinal product to reduce the concentration of cerebral natriuretic peptide in plasma. 10. Применение фармацевтической композиции по любому из пп.1 и 2 для приготовления лекарственного препарата для уменьшения некроза миокарда.10. The use of the pharmaceutical composition according to any one of claims 1 and 2 for the preparation of a medicinal product to reduce myocardial necrosis. 11. Применение фармацевтической композиции по любому из пп.1 и 2 для приготовления лекарственного препарата для уменьшения фиброза миокарда. 11. The use of the pharmaceutical composition according to any one of claims 1 and 2 for the preparation of a medicinal product to reduce myocardial fibrosis.
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CN102048895B (en) * 2011-01-17 2012-08-22 王仁平 Pure traditional Chinese medicine preparation for treating dilated cardiomyopathy
CN102416036B (en) * 2011-12-09 2014-05-07 上海市中医医院 Traditional Chinese medicinal compositions for preventing and treating ventricular reconstruction due to coronary heart disease and use thereof
CN102526673B (en) * 2012-02-06 2013-09-04 王健 Chinese medicine capsule, Chinese medicine liquid and health-care oral liquid for treating dilated cardiomyopathy and manufacture method
CN102526676B (en) * 2012-02-09 2013-09-25 青岛华仁技术孵化器有限公司 Traditional Chinese medicine for treating chronic heart failure, preparation method and administration mode
CN102670965A (en) * 2012-05-29 2012-09-19 成都绿迪科技有限公司 Traditional Chinese medicine preparation for curing dilated cardiomyopathy
CN102697875A (en) * 2012-06-15 2012-10-03 李良 Safflower carthamus traditional Chinese medicine decoction for treating palpitation and preparation method for decoction
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